Clinical trials: Skin Wrinkling
Healthy, Wrinkle
Safety and Efficacy Study of Vasu Facial Beauty Oil
This is an open-label, single-arm, single-center, proof-of-concept, exploratory, safety and efficacy, clinical study of a Vasu Facial Beauty Oil in healthy adult human subjects.
- Conditions
- Healthy, Wrinkle, Dry Skin, Skin Pigment
- Trial name
- NCT05646953
- Testing
- Facial Beauty Oil
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Skin Manifestations, Wrinkle
A 56-day Clinical Study on Facial Skin Rejuvenation
This clinical trial aims to learn about the efficacy of MLYAAT-1002® (a proprietary anti-aging complex, MLYAAT is short for "multi-layer anti-ageing technology" ) in female subjects who have newly received the rejuvenation…
- Conditions
- Skin Manifestations, Wrinkle, Photoaging
- Trial name
- NCT06188338
- Testing
- Fractional picosecond laser treatment followed by daily use of formulations containing MLYAAT-1002®., Fractional picosecond laser treatment followed by daily use of formulations without MLYAAT-1002®
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Botanee Group Co., Ltd.
Skin Wrinkling
Emervel Classic Lidocaine Versus Juvederm® Ultra in Treatment of Moderate to Severe Facial Wrinkles and Folds
The purpose of this study is to compare the effectiveness and safety of Emervel Classic Lidocaine versus Juvederm® Ultra in the treatment of moderate to severe facial wrinkles and folds.
- Trial name
- NCT01205048
- Testing
- Emervel Classic Lidocaine, Juvederm® Ultra
- Where
- 12 sites in United States
- Volunteers
- 171 people
- Sponsor
- Galderma R&D
Skin Laxity, Wrinkles
Safety and Efficacy Evaluation of High Intensity Focused Ultrasound Device in Eyebrow Lifting
The goal of this clinical trial is to assess the safety and efficacy of the high-intensity focused ultrasound (HIFU) device, ULTRAFORMER MPT (UF4-M400), developed by CLASSYS Inc., for eyebrow lifting.
- Conditions
- Skin Laxity, Wrinkles, Facial Wrinkles and Rhytides Reduction
- Trial name
- NCT06724510
- Testing
- HIFU treatment with ULTRAFOMER MPT
- Where
- 4 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Senescence Wrinkles, Acne, Pitting Scar
Safety Study of Filler Agent Composed of Umbilical Cord Mesenchymal Stem Cells and Hyaluronic Acid
The overall goal of this study is to evaluate the safety and exploratory efficacy of the injectable filler agent composed of umbilical cord mesenchymal stem cells and hyaluronic acid for the improvement of wrinkles, acne, pitting…
- Trial name
- NCT02698813
- Testing
- umbilical cord mesenchymal stem cells and hyaluronic acid, hyaluronic acid
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- South China Research Center for Stem Cell and Regenerative Medicine
Décolletage
Sculptra for Décolletage Crepiness and Wrinkling
The purpose of this study is to evaluate the safety and efficacy of Sculptra as a volume agent to improve décolletage crepiness and wrinkling.
- Trial name
- NCT03508973
- Testing
- Sculpta
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Skin Laser & Surgery Specialists
Wrinkle, Fatigue
Anti-ageing Efficacy of a Cosmetic Formulation Containing NMN (2%) Versus Placebo
The study aims at evaluating skin wrinkling, puffiness and fatigue and dark circle appearance on asian and african-american healthy volunteer cohorts receiving a cosmetic formulation containing NMN (2%).
- Conditions
- Wrinkle, Fatigue, Puffiness Around the Eyes
- Trial name
- NCT04685096
- Testing
- Test product creme, Reference creme
- Where
- 2 sites in United States, China
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Seneque SA
Facial Wrinkles, Skin Aging
A Study to Evaluate the Safety and Effectiveness of the Cryo-Touch II Device for the Treatment of Forehead and/or Glabellar Lines
A prospective, non-randomized, multicenter study to evaluate the safety and effectiveness of the cryo-touch II device for the treatment of forehead and/or glabellar lines
- Trial name
- NCT01447342
- Testing
- Cryo-Touch II
- Where
- 3 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Skin Aging
Efficacy of a Dietary Supplement on Parameters of Skin Aging in Men and Women
As the body ages, the skin experiences natural changes in structure and composition. These changes may manifest visibly as increased skin dryness, wrinkling, and a loss of firmness/elasticity.
- Trial name
- NCT06083402
- Testing
- HyaCera™
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Natals, Inc. dba Ritual
Skin Aging, Facial Rhytides
AnteAGE Biosomes With Radiofrequency Microneedling for Facial Skin Rejuvenation
This prospective, randomized controlled study evaluated the efficacy and tolerability of AnteAGE Biosome Solution used in conjunction with facial radiofrequency microneedling.
- Conditions
- Skin Aging, Facial Rhytides, Skin Tone
- Trial name
- NCT07849556
- Testing
- AnteAGE Biosome Treatment Solution, Radiofrequency Microneedling, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Wrinkle, Skin Laxity
A 28-day Clinical Study on Facial Skin Rejuvenation
This clinical trial aims to learn about the efficacy of MLYAAT-1002® (a proprietary anti-aging complex, MLYAAT is short for "multi-layer anti-ageing technology" ) in female subjects who have newly received the rejuvenation…
- Conditions
- Wrinkle, Skin Laxity, Skin Manifestations, Skin
- Trial name
- NCT06140628
- Testing
- Fotona4D Pro® treatment followed by daily use of formulations containing MLYAAT-1002®, Fotona4D Pro® treatment followed by daily use of formulations without MLYAAT-1002®
- Where
- China
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Botanee Group Co., Ltd.
Skin Wrinkles on Face and Neck Areas
Study to Determine Effectiveness of Activation Mist on Facial Skin Wrinkles
To determine the effect of Activation Mist (AM) on skin wrinkles and appearance.
- Trial name
- NCT01939964
- Testing
- Activation Mist
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- California Allergy and Asthma Medical Group, Inc.
Wrinkle
Topical Palm Tocotrienols on Skin Biophysical Properties
A single-center, double-blind, randomised, placebo-controlled parallel-group study. Selected subjects will be randomised into active and control groups in a ratio of 1:1.
- Trial name
- NCT05787743
- Testing
- Facial cream with 2% palm tocotrienols extract, Base cream
- Where
- Malaysia
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Hirsutism, Hypertrichosis
Enhanced Safety Aesthetic Laser System
The purpose of this study is to determine whether a new laser system provides better safety and efficacy than existing lasers in popular cosmetic procedures such as hair removal, treatment of cosmetically disturbing vascular…
- Conditions
- Hirsutism, Hypertrichosis, Telangiectases, Rhytides
- Trial name
- NCT00495443
- Testing
- Peterio
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Scilex Ltd.
Skin Health
Nutritional Study of Fish Oil in Skin Quality in Healthy Women
The skin acts as a barrier against the external environment and prevents water loss from the body. Aging is a natural process leading to changes in the skin and fish oil has been shown to prevent inflammation, hyperpigmentation…
- Trial name
- OPTIHUD (NCT05128240)
- Testing
- Ceto 10
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Epax Norway AS
Skin Wrinkles
Study on the Safety, Efficacy of Home RF Cosmetic Instrument in the Treatment of Facial or Periorbital Wrinkles（F-MFR300-RD-003）
This is a multicenter trial with randomized control and evaluator blind method, which meets the screening criteria total of 224 subjects were enrolled and randomly divided into control group and experiment according to 1:1 ratio…
- Trial name
- NCT06565884
- Testing
- Home radiofrequency skin treatment instrument, Ultrasonic coupler for medical purposes
- Where
- China
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Flossom (GD) Beauty Technology Co., Ltd.
Perioral Lines
A Study to Assess Adverse Events and Effectiveness of Intradermally Injected JUVÉDERM® VOLITE™ Gel Filler in Adult Participants in China With Fine Lines Around the Mouth
Facial fine lines and wrinkles are caused by skin thinning, loss of moisture, and loss of elasticity due to factors such as age, ultraviolet (UV) radiation, and environmental exposures.
- Trial name
- NCT05454033
- Testing
- JUVÉDERM® VOLITE™, Control
- Where
- 11 sites in China
- Volunteers
- 198 people
- Sponsor
- AbbVie
Aging
Evaluation of Anti-aging Performance and Tolerance of a Hyaluronic Acid-based Filler NCTF135HA®
The NCTF135HA medical device from Laboratoires FILL-MED by FILORGA Company is an injectable solution for the treatment of wrinkles and biorevitalization of injected mature skin using a multi-injection technique with CE marking.
- Trial name
- HEBE2 (NCT05609617)
- Testing
- injection, Cream application
- Where
- France
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Laboratoires FILLMED
Skin, Skin Manifestations
Placebo Controlled Efficacy Evaluation of the Hydrolyzed Collagen Peptide In Adult Females
The aim of this study is to evaluate the contribution of hydrolized collagen products to elasticity, hydration and roughness of the skin of female volunteers.
- Conditions
- Skin, Skin Manifestations, Wrinkle
- Trial name
- NCT05235997
- Testing
- Hydrolized Collagen Peptide
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sel Sanayi Urunleri Ticaret ve Pazarlama A.S.
Peri-orbital Rhytides
Ablative Fractional Lasers to Treat Peri-orbital Rhytides
Ablative fractional lasers were introduced for treating facial rhytides in an attempt to achieve results comparable to traditional ablative resurfacing but with fewer side effects.
- Trial name
- NCT00990431
- Testing
- Fractional carbon dioxide laser treatment, Fractional erbium:YAG laser treatment
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Laserklinik Karlsruhe