Clinical trials: Skin to Skin
Cutaneous Lupus Erythematosus
To Evaluate the Preliminary Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of CC-11050 in Subjects With Discoid Lupus Erythematosus and Subacute Cutaneous Lupus Erythematosus
This is the first study in cutaneous lupus erythematosus subjects to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of CC-11050.
- Trial name
- NCT01300208
- Testing
- CC-11050
- Where
- 19 sites in United States
- Volunteers
- 48 people
- Sponsor
- Amgen
Skin Recovery
A Study to Gain Information How Well Dexpanthenol Dermal Spray Helps the Skin to Recover After Laser Hair Removal in the Groin and Intimate Area
In this study, researchers want to learn more about the effect of dexpanthenol dermal spray on skin recovery after a dermatological procedure for hair removal (laser depilation) in the groin and intimate area in adult women.
- Trial name
- NCT03853525
- Testing
- BAY207543 (Bepanthol, Bepantol® Derma Spray), Semisolid vaseline
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Chronic Spontaneous Urticaria
A Study to Investigate the Use of Benralizumab in Patients With Chronic Spontaneous Urticaria Who Are Symptomatic Despite the Use of Antihistamines (ARROYO)
The purpose of this study is to investigate the use of benralizumab is effective in the treatment of chronic spontaneous urticaria (CSU) who are symptomatic despite the use of antihistamines.
- Trial name
- ARROYO (NCT04612725)
- Testing
- Benralizumab
- Where
- 40 sites in United States, Bulgaria and 5 more
- Volunteers
- 159 people
- Sponsor
- AstraZeneca
Plaque Psoriasis
A Study to Assess the Effects of Switching From a Biologic Treatment to Tildrakizumab Using Patient-reported Outcomes in Adult Participants With Moderate to Severe Plaque Psoriasis
The main aim of this study is to assess the effects of switching from another biologic to tildrakizumab on patient-reported outcomes and to assess psoriasis intensity, patient's quality of life prior and after switching and the…
- Trial name
- NCT06030076
- Testing
- Tildrakizumab
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Almirall, S.A.
Rheumatoid Arthritis
Efficacy Study of MM-093 in Rheumatoid Arthritis Patients on Methotrexate (MTX)
The purpose of this clinical study is to see if an experimental drug, called MM-093, is safe and effective in the treatment of rheumatoid arthritis.
- Trial name
- NCT00105976
- Testing
- MM-093
- Where
- 38 sites in United States
- Volunteers
- 260 people
- Sponsor
- Merrimack Pharmaceuticals
Leg Ulcers
Safety Evaluation of Biatain Ibu in Painful Chronic Venous Leg Ulcers
The objective of this open label extension study (extension to study DK143WS) is to evaluate the safety of Biatain Ibu during 6 -12 weeks of exposure and during a 40 - 46 weeks safety follow-up period.
- Trial name
- NCT00628004
- Testing
- Biatain Ibu, Local best practice
- Where
- 5 sites in Denmark, Germany and 1 more
- Volunteers
- 93 people
- Sponsor
- Coloplast A/S
Incontinence-associated Dermatitis
Prospective Explorative Research Study of Comparison of Biomarkers Related to Incontinence Associated Dermatitis (IAD) From Skin Swabs
The aim of this explorative study is to collect information about biomarkers that differentiate skin affected by Incontinence Associated Dermatitis (IAD) from non-affected skin.
- Trial name
- BioSens (NCT07816549)
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Essity Hygiene and Health AB
Acne Vulgaris
A Study to Evaluate the Efficacy and Safety of Topical Administration of FMX101 in the Treatment of Moderate-to-Severe Acne Vulgaris
A Randomized, Double-Blind, Vehicle-Controlled Study to Evaluate the Efficacy and Safety of Topical Administration of FMX101 for 12 Weeks in the Treatment of Moderate-to-Severe Acne Vulgaris (Study FX2017-22)
- Trial name
- NCT03271021
- Testing
- FMX101, Vehicle Foam
- Where
- 98 sites in United States
- Volunteers
- 1,488 people
- Sponsor
- Vyne Therapeutics Inc.
Atopic Dermatitis
A Clinical Trial to Compare Topical Agents in Adults With Mild to Moderate Atopic Dermatitis (AD)
An Explorative Clinical Trial to Evaluate an Intra Patient Comparison Design of Topical Agents in Adults with Mild to Moderate Atopic Dermatitis.
- Trial name
- NCT02376049
- Testing
- Pimecrolimus cream, Betamethasone dipropionate cream, Clobetasol propionate cream
- Where
- 2 sites in Canada, Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Rheumatoid Arthritis
A Study to Evaluate the Pharmacokinetics of ASP1707 and Methotrexate in Patients With Rheumatoid Arthritis
The primary purpose of the study is to evaluate the effect of ASP1707 twice daily on the pharmacokinetics of once weekly oral methotrexate (MTX).
- Trial name
- NCT02867306
- Testing
- ASP1707, methotrexate (MTX)
- Where
- Moldova
- Volunteers
- 10 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Plaque Psoriasis
LAS41008 in Moderate to Severe Chronic Plaque Psoriasis
The aim of the study is to evaluate the efficacy and safety of LAS41008 in comparison to active control and placebo in patients with moderate to severe chronic plaque psoriasis
- Trial name
- NCT01726933
- Testing
- LAS41008, LASW1835
- Where
- 4 sites in Austria, Germany and 2 more
- Volunteers
- 839 people
- Sponsor
- Almirall, S.A.
Lax Skin
Renuvion APR Device to Improve the Appearance of Lax Tissue in the Neck and Submental Region
This is a prospective, multi-center, multi-phase, evaluator-blinded study of subjects undergoing a procedure with the Renuvion APR Device to improve the appearance of lax tissue in the neck and submental region.
- Trial name
- NCT04146467
- Testing
- Renuvion APR Device
- Where
- 6 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Apyx Medical
Venous Leg Ulcer
Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of Therapy-resistant CVU (Phase III)
The aim of this clinical trial is to investigate the efficacy and safety of allo-APZ2-CVU, administered topically on therapy-resistant non-healing CVUs compared to placebo.
- Trial name
- NCT06489028
- Testing
- allo-APZ2-CVU
- Where
- 15 sites in United States, Austria and 10 more
- Volunteers
- 250 people
- Sponsor
- RHEACELL GmbH & Co. KG
Atopy, Skin Barrier to Water Loss
Clinical Evaluation of an Atopic Skin Product Containing Picea Abies Resin Extract
This study evaluates the repairing efficacy of a cosmetic cream containing Picea abies extract compared to a placebo (cream without extract) and a benchmark product.
- Trial name
- NCT07573592
- Testing
- Atopic cream with Picea abies resin extract, Aqualan-L Cream
- Where
- Italy
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Repolar Pharmaceuticals Oy
Ankylosing Spondylitis, Psoriatic Arthritis
Study Evaluating Epidemiology of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis in Australia
The study is a cross sectional, epidemiology study of disease severity for rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis in four geographic regions in Australia (Illawarra, Sutherland, Hunter Urban and…
- Conditions
- Ankylosing Spondylitis, Psoriatic Arthritis, Rheumatoid Arthritis
- Trial name
- NCT00751387
- Where
- 4 sites in Australia
- Volunteers
- 559 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Cutaneous Melanoma, Uveal Melanoma
A Study of RO7293583 in Participants With Unresectable Metastatic Tyrosinase Related Protein 1 (TYRP1)-Positive Melanomas
This is a first-in-human, multi-center clinical study to determine the safety, Maximum Tolerated Dose (MTD) and/or Optimal Biological Dose (OBD) as well as the optimal schedule for intravenous (IV) and/or subcutaneous (SC)…
- Conditions
- Cutaneous Melanoma, Uveal Melanoma, Mucosal Melanoma
- Trial name
- NCT04551352
- Testing
- RO7293583, Tocilizumab, Obinutuzumab
- Where
- 14 sites in United States, Australia and 4 more
- Volunteers
- 20 people
- Sponsor
- Hoffmann-La Roche
Eczema
Study to Evaluate the Efficacy and Safety of ZL-3101 in Subjects With Subacute Eczema
This is a double-blind, randomized, placebo-controlled multi-center phase IIA study to evaluate the clinical efficacy and safety of Fugan ointment versus placebo applied to involved skin of subjects with mild to moderate subacute…
- Trial name
- NCT03134352
- Testing
- ZL-3101
- Where
- 6 sites in China
- Volunteers
- 290 people
- Sponsor
- Zai Lab Pty. Ltd.
Laparoscopy, Tissue Adhesion, Surgery-Induced
The Efficacy and Safety of Medicurtain® in Patients With Total Laparoscopic Hysterectomy (Pivotal Study)
This study was designed to assess the safety and efficacy of MEDICURTAIN. Patients who underwent total laparoscopic hysterectomy were randomly assigned either into Medicurtain® treatment group or non-treatment control group.
- Conditions
- Laparoscopy, Tissue Adhesion, Surgery-Induced, Leiomyoma of the Uterine Body
- Trial name
- NCT04672421
- Testing
- Medicurtain®
- Where
- South Korea
- Volunteers
- 107 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Xeroderma Pigmentosum
A Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Xeroderma Pigmentosum (XP)
The CUV156 study will evaluate the safety of afamelanotide in XP-C patients, as well as the drug's ability to assist reparative processes following ultraviolet (UV) provoked DNA damage of the skin.
- Trial name
- NCT05159752
- Testing
- Afamelanotide
- Where
- Germany
- Volunteers
- 6 people
- Sponsor
- Clinuvel Europe Limited
Dermatitis, Atopic Dermatitis
Efficacy and Safety Study of Apremilast in Subjects With Moderate to Severe Atopic Dermatitis
A study to evaluate the efficacy and safety of apremilast (CC-10004) in subjects with moderate to severe atopic dermatitis
- Trial name
- NCT02087943
- Testing
- Apremilast
- Where
- 31 sites in United States, Canada and 1 more
- Volunteers
- 191 people
- Sponsor
- Amgen
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