Clinical trials: Skull
Vestibular Schwannoma
Gentamicin Treatment Prior to Schwannoma Surgery - No Residual Function
The purpose of the study is to determine whether vestibular and postural compensation following schwannoma surgery is improved by ablating vestibular function prior to surgery, even if vestibular function is absent according to…
- Trial name
- NCT02415257
- Testing
- Gentamicin
- Where
- Sweden
- Sponsor
- Lund University
Mandible Tumor
Mandibular Reconstruction Bone Plate
The purpose of this study is to evaluate the reliability of using mandibular osteosynthesis a 2.3mm reconstruction bone plate in the maintenance of the space, contour, and mandibular bone preservation during marginal mandibular…
- Trial name
- NCT06099431
- Testing
- Mandibular marginal resection and reconstruction, mandibular osteosynthesis a 2.3mm reconstruction bone plate
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanta University
CSF Leak
The Paediatric EVICEL® Neuro Study
The purpose of this study is to evaluate the safety and efficacy of EVICEL® when used for suture-line sealing in dura-mater closure in elective or urgent paediatric cranial neurosurgery to provide intraoperative watertight…
- Trial name
- NCT02309645
- Testing
- EVICEL® Fibrin Sealant, Sutures Only
- Where
- 7 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Ethicon, Inc.
Trigeminal Neuralgia
Magnetic Resonance Imaging Study on Patients With Trigeminal Neuralgia
Up to now, multiplanar reconstruction (MPR) has been widely used to detect the neurovascular compressions (NVC) on the patients with idiopathic trigeminal neuralgia (ITN).
- Trial name
- MRI-TN (NCT02713646)
- Where
- China
- Volunteers
- 55 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Brain Injuries, Hematoma of Head
Comparison of Cranioplasty With PEEK and Titanium
Decompressive craniectomy is suggested as an effective surgical intervention for patients with high intracranial pressure. Recently, various customized artificial materials are increasingly employed, e.g., titanium and…
- Conditions
- Brain Injuries, Hematoma of Head, Skull Defect
- Trial name
- NCT04707404
- Testing
- Cranioplasty
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Mandibular Nerve Injury
Study on the Risk of Inferior Alveolar Nerve Damage During Lower Third Molar Surgery
Objective The present study aimed to evaluate which factors were statistically associated with a greater probability of inferior alveolar nerve (IAN) damage during lower third molar surgery.
- Trial name
- NCT04807946
- Testing
- lower third molar extraction
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor
Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01
RATIONALE: Treatment for pediatric extracranial germ cell tumors may cause side effects and secondary cancers later in life. A study that evaluates patients after receiving combination chemotherapy or surgery may help doctors…
- Conditions
- Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Gastrointestinal Complications, Infertility
- Trial name
- NCT00436774
- Testing
- assessment of therapy complications, quality-of-life assessment
- Where
- 13 sites in Ireland, United Kingdom
- Volunteers
- 60 people
- Sponsor
- Children's Cancer and Leukaemia Group
Strabismus
Mobile Medical Application for Cost-effective Strabismus Screening
Develop and evaluate a new smartphone based app to screen for and measure eye misalignment (strabismus). The investigators will validate the app against simulated strabismus of known magnitude and common clinical tests.
- Trial name
- NCT03450980
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Dissociated Vertical Deviation, Inferior Oblique Overaction
Inferior Oblique Muscle Anteriorization Versus Anteriorization and Resection in DVD With IOOA
The goal of this clinical trial is to compare the results of two surgical modalities in patients with Dissociated vertical deviation with inferior oblique muscle overaction .
- Trial name
- NCT05980962
- Testing
- Inferior oblique anteriorization, Inferior oblique anteriorization together with unliateral resction
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Kasr El Aini Hospital
Vestibular Schwannoma
Enhancing Facial Nerve Function With Omega-3 After Resection of Vestibular Schwannoma
The purpose of this research is to develop a therapeutic agent to help improve facial nerve outcomes and ultimately improve long-term quality-of-life following surgical resection of vestibular schwannomas.
- Trial name
- EFFORTS (NCT05116878)
- Testing
- Omega-3
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Vestibular Diseases, Vestibular Neuronitis
Prednisone Treatment for Vestibular Neuronitis
The purpose of the study is to investigate the value of steroids in the treatment of vestibular neuronitis. The potential benefits of steroid therapy would be analyzed by the clinical response, self-perceived handicap and…
- Trial name
- NCT00271791
- Testing
- Prednisone
- Where
- 4 sites in Israel
- Volunteers
- 17 people
- Sponsor
- Carmel Medical Center
Trigeminal Neuralgia
The Clinical Benefits of the Combination Use of Acupuncture and Antihistamine on Trigeminal Neuralgia
Trigeminal neuralgia is a paroxysmal extreme pain and is an unmet clinical need, we hope that our discovery about the antihistamine and acupuncture can be used in the treatment trigeminal neuralgia.
- Trial name
- NCT04384224
- Testing
- acupuncture
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- China Medical University Hospital
Dystonia Disorder
Impact of rTMS on Abnormal Cortical fMRI in Patients With Dystonia
By tracking resting-state fMRI scans, we aim to discover how repetitive transcranial magnetic stimulation (rTMS) changes brain connectivity in individuals with dystonia.
- Trial name
- NCT07626216
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Northwell Health
Fibromyalgia
Randomized Controlled Trial of CES for Fibromyalgia
Given recent increasing opioid-related deaths and evidence showing against the use of opioids for non-malignant chronic pain, there is growing need for non-narcotic pain management.
- Trial name
- NCT04115033
- Testing
- Alpha-stim
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Mandible Fracture
Forensic Dental Age Estimation : Validation of Computed Tomography for Third Molar Demirjian's Staging
Age can be estimated in different ways by using skeletal age and dental age. Currently, bone age is determine thanks to the wrist x-rayed, and the dental age using variation in mineralization (Demirjian's score) on the dental…
- Trial name
- SCAO (NCT04907552)
- Where
- France
- Volunteers
- 557 people
- Sponsor
- University Hospital, Montpellier
Myofacial Pain Syndromes
KT vs IASTM on Upper Trapezius Myofascial Trigger Points To Compare Effect of KT VS IASTM on Pain Intensity, Pain Pressure Threshold, Cervical Range of Motion and Functional Disability Level.
This study would answer the following question: Is there a difference in the effects between IASTM and KT on pain intensity level, pain pressure threshold, cervical range of motion (ROM), functional disability level and…
- Trial name
- NCT06899685
- Testing
- tradional physical therapy treatment, KT, IASTM
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Reham Sayed Mesaed
Optic Neuritis
Lipoic Acid as a Treatment for Acute Optic Neuritis
The purpose of this study is to determine if oral lipoic acid can safely help relieve permanent optic nerve injury in patients diagnosed with acute optic neuritis.
- Trial name
- NCT01294176
- Testing
- Lipoic Acid
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Oregon Health and Science University
Leak, Cerebrospinal Fluid
CraniSeal Post Approval Study
To collect post-approval data comparing the safety and effectiveness of CraniSeal Dural Sealant to DuraSeal Dural Sealant. The study has been powered specifically to determine whether the CraniSeal device when used as an adjunct…
- Trial name
- NCT06406790
- Testing
- CraniSeal, DuraSeal
- Where
- 8 sites in United States
- Volunteers
- 224 people
- Sponsor
- Pramand LLC
Subcondylar Process of Mandible Open Fracture, Facial Nerve Injuries
Evaluation of Preauricular Retromandibular Anteroparotid Versus Retromandibular Through Parotid Approach
Of all the bones in the maxillofacial area, the condylar process is the most susceptible to fracture. The incidence of condylar fracture accounts for 25% to 50% of all mandibular fractures.
- Trial name
- NCT03803150
- Testing
- PRA approach, RT approach
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vocal Cord Paralysis
Voice Rest and Injection Laryngoplasty
The purpose of this study is to evaluate the subjective, objective, and aerodynamic impact of voice rest following injection augmentation and compare the outcomes to patients with no post-procedure voice restrictions.
- Trial name
- NCT05542550
- Testing
- Voice Rest, No Voice Rest
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Virginia
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