Clinical trials: Skull
Primary Extra-cranial Solid Tumor, Recurrent or Refractory Glypican 3 (GPC3)
A Study of Codrituzumab in Children and Young Adults With Solid Tumors and Have Not Responded to Treatment or Have Come Back After Treatment
The purpose of this study to find out whether codrituzumab is a safe treatment that causes few or mild side effects in children and young adults who have solid tumors that express the protein GPC3.
- Trial name
- NCT04928677
- Testing
- Codrituzumab
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder
A Randomized Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO (PREVENT Study)
The objectives of this time-to-event study were to assess the efficacy and safety of eculizumab as compared with placebo in participants with neuromyelitis optica spectrum disorder (NMOSD) who were anti-aquaporin-4 (AQP4)…
- Trial name
- NCT01892345
- Testing
- Eculizumab
- Where
- 70 sites in United States, Argentina and 16 more
- Volunteers
- 143 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Chronic Pain, Anxiety
Phase II Trial of Nu-V3 Non-Invasive Nerve Stimulation Device for Chronic Pain, Anxiety, Depression, Sleeplessness
This Nu-V3 clinical study is a randomized, phase II, open-label study evaluating the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3P2RCT (NCT05394545)
- Testing
- Nu-V3
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nu-Life Solutions
Bell's Palsy
Efficacy of Laser Acupuncture for Idiopathic Bell's Palsy
Objective: Bell's palsy is characterized by acute, unilateral onset that compromises function and esthetics, exerting a considerable impact on the social, professional, and psychological aspects of the lives of affected…
- Trial name
- NCT06280794
- Testing
- Laser acupuncture, Steroids
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Beijing Tongren Hospital
Bladder Cancer
Prophylactic Cranial Irradiation (PCI) for Small Cell Carcinoma of the Urothelium
The goal of this clinical research study is to learn if whole brain radiation can lower the chances of developing brain tumors in patients with small cell carcinoma of the urinary tract, including the bladder.
- Trial name
- NCT00756639
- Testing
- Prophylactic Cranial Irradiation (PCI), Brain X-ray
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- M.D. Anderson Cancer Center
Recurrent Paralysis of Vocal Cords
Efficacy of Oral Corticosteroid Therapy in Recurrent Paralyzes After Thyroidectomy
Thyroidectomy is a common surgical procedure in France. Recurrent paralysis is one of the main complications. Oral corticosteroid therapy are frequently used at a dosage of 1mg/kg for seven days, in case of recurrent paralysis to…
- Trial name
- NCT03553342
- Testing
- Corticoids
- Where
- France
- Volunteers
- 156 people
- Sponsor
- Poitiers University Hospital
Bell Palsy
Laser Acupuncture for Idiopathic Bell's Palsy
Bell's palsy is characterized by acute, unilateral onset that compromises function and esthetics, exerting a considerable impact on the social, professional, and psychological aspects of the lives of affected individuals.
- Trial name
- NCT06732622
- Testing
- Laser acupuncture, Steroids
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Beijing Tongren Hospital
NMO Spectrum Disorder
Efficacy and Safety of Transcranial Temporal Interference Stimulation (tTIS) for Neuropathic Pain in Neuromyelitis Optica Spectrum Disorder (NMOSD)
This is an open-label, single-arm, single-center prospective pilot study to assess the efficacy and safety of transcranial temperol interference stimulation in patients with neuromyelitis optica spectrum disorder (NMOSD)…
- Trial name
- NCT07377305
- Testing
- 10Hz tTIS (2-4mA) Intervention
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Tang-Du Hospital
Surgical Procedure, Unspecified, Ocular Discomfort
Lateral Rectus Muscle Tendon Elongation
To evaluate a technique using resected medial rectus muscle transplantation for elongation of Lateral rectus tendon as a monocular surgery for large angle sensory exotropia.
- Conditions
- Surgical Procedure, Unspecified, Ocular Discomfort, Strabismus, Divergent
- Trial name
- NCT04286945
- Testing
- LATERAL RECTUS MUSCLE AUGMENTED RECESSION BY ELONGATION OF THE TENDON WITH AUTOGRAFT FROM RESECTED MEDIAL RECTUS MUSCLE
- Volunteers
- 16 people
- Sponsor
- Tanta University
Myofacial Pain Syndrome
Intramuscular Electrical Stimulation on Upper Trapezius With Trigger Points
The prevalence of myofascial pain ranges from 30 to 93% and can result in sensorimotor and autonomic deficits. In routine neuromuscular electrical stimulation, conventional electrode placement (CEP) and inverse electrode…
- Trial name
- NCT06604962
- Testing
- IMES using IEP, IMES using CEP
- Where
- United Arab Emirates
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Optic Neuritis
Initial Clinical Presentation of Inflammatory Optic Neuritis Associated or Not With Autoantibodies Anti-Myelin-oligodendrocyte-glycoprotein
In eight ophthalmic units, the investigator will include all inflammatory optic neuritis (ON) during acute phase and rank them in two groups: 1/ ON with autoantibodies anti-myelin-oligodendrocyte-glycoprotein (ON MOG+) 2/ ON…
- Trial name
- MOG (NCT03345537)
- Testing
- Non interventional study
- Where
- 8 sites in France
- Volunteers
- 103 people
- Sponsor
- Nantes University Hospital
Depression, Domestic Violence
Acupuncture for Women Victims of Domestic Violence With Psychiatric Sequelae
This is an assessor-blinded, randomized controlled trial. A total of 110 women victims of domestic violence aged 18-65 years will be recruited from local community centers and domestic violence shelters (refugee centers).
- Conditions
- Depression, Domestic Violence, Psychiatric Disorder
- Trial name
- NCT05102253
- Testing
- Dense cranial electroacupuncture stimulation (DCEAS), Transcutaneous electrical acupoint stimulation (TEAS), Wait-list control: Routine care
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- The University of Hong Kong
Amblyopia, Strabismus
VISION-3D: Visual Skills Improvement With On-screen 3D Movies.
This clinical study investigates whether watching 3D films can help improve the vision of children with residual amblyopia (lazy eye), that is, those children who, despite having undergone usual treatments such as glasses or…
- Trial name
- VISION3D (NCT07301645)
- Testing
- Stereoscopic (3D) Movie Viewing, 2D Movie Viewing
- Volunteers
- 40 people
- Sponsor
- Universitat Politècnica de Catalunya
Skull Fractures
Skull Fractures in Pediatric Emergency Department: the Ultrasound Protocol
The aim of this clinical trial is to compare musculoskeletal ultrasound with the reference standard diagnostic test (cranial CT scan) in patients with minor head trauma associated with scalp hematoma and suspected skull fracture.
- Trial name
- SPEED-UP (NCT07636902)
- Testing
- Skull ultrasound
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Giannina Gaslini
Chordoma
Proton Beam Therapy for Chordoma Patients
The goal of this clinical research study is to learn if proton beam therapy, with or without photon beam radiation therapy, is effective in the treatment of skull base chordoma. The safety of this treatment will also be studied.
- Trial name
- NCT00496119
- Testing
- Proton Beam Therapy, Photon Beam Therapy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- M.D. Anderson Cancer Center
Plagiocephaly, Scaphocephaly
Cranial Cup Use for the Prevention of Positional Head Shape Deformity in the NICU
Many hospitalized infants can develop a flattening of the back or sides of their head. This condition develops gradually when an infant's head rests on a firm or semi-firm surface for a prolonged period of time.
- Conditions
- Plagiocephaly, Scaphocephaly, Brachycephaly
- Trial name
- NCT01218087
- Testing
- Cranial cup device and Moldable positioner, Moldable positioner device
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Boston Children's Hospital
Supranuclear Palsy, Progressive
Extension Study of BIIB092 in Participants With Progressive Supranuclear Palsy (PSP) Who Participated in CN002003
The purpose of this study is to evaluate the long-term safety and tolerability of multiple intravenous (IV) infusions of BIIB092 in participants with Progressive Supranuclear Palsy (PSP).
- Trial name
- NCT02658916
- Testing
- BIIB092
- Where
- 13 sites in United States
- Volunteers
- 47 people
- Sponsor
- Biogen
Anesthesia Complication, Surgical Blood Loss
Cerebral Oxygenation, Different Measurement Points and Their Correlation in Pediatric Population
Children who undergo surgery routinely for surgery that risk high levels of circulatory changes (eg heart surgery) is currently used routinely monitoring as regional oxygenation technology of the brain (NIRS).
- Trial name
- NCT03136952
- Testing
- NIRS frontal and occipital
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Göteborg University
Head and Neck Cancer
Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants
RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future.
- Trial name
- NCT00898638
- Testing
- biologic sample preservation procedure, medical chart review
- Where
- 4 sites in United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Optic Neuropathy
STReetlab Assessment Tool of Activities Daily Living in Glaucoma Patient
The impact of glaucomatous optic neuropathy on the daily life of patients is poorly characterized and does not benefit from standardized tests.
- Trial name
- STRATAL-GL (NCT05747781)
- Testing
- Pilot Phase: standardized behavioral task, Validation Phase: standardized behavioral task
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
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