Clinical trials: Sleep Apnea Hypopnea Syndrome
Obstructive Sleep Apnea, Down Syndrome
Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome
The goal of this observational study is to learn about the use of non-invasive ventilation for treatment of obstructive sleep apnoea syndrome in children with Down Syndrome.
- Conditions
- Obstructive Sleep Apnea, Down Syndrome, Quality of Life, Behavior
- Trial name
- REFRESHED (NCT06030349)
- Testing
- Non-invasive ventilation
- Where
- 6 sites in Ireland, United Kingdom
- Volunteers
- 200 people
- Sponsor
- Children's Health Ireland
Apnea
Efficacy of Different Treatments for Obstructive Sleep Apnea
This was a prospective randomized controlled clinical trial that aimed to evaluate the efficacy of three treatments for obstructive sleep Apnea OSA: 1. Conventionally constructed mandibular advancement device (MAD). 2.
- Trial name
- NCT06352658
- Testing
- Conventional mandibular advancement device, CAD CAM mandibular advancement device, Uvuloplatopharyngeoplasty UPPP
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Nourhan M.Aly
Obstructive Sleep Apnea
Benefits of Telemedicine in CPAP Treatment
Continuous positive airway pressure (CPAP) is the first choice of treatment for moderate to severe obstructive sleep apnea syndrome (OSAS).
- Trial name
- NCT03202602
- Testing
- Telemonitoring of CPAP treatment, Standard care
- Where
- Sweden
- Volunteers
- 216 people
- Sponsor
- Uppsala University
Obstructive Sleep Apnea
The Impact of Daily Sinus Irrigation on Nasal Symptoms in Continuous Positive Airway Pressure (CPAP) Users - A Pilot Study
Continuous positive airway pressure (CPAP) is the most commonly used treatment for obstructive sleep apnea. Nasal symptoms such as dryness, itching and congestion are common in CPAP users.
- Trial name
- NCT01121445
- Testing
- NeilMed nose and sinus irrigation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Bridgeport Hospital
Obesity Hypoventilation Syndrome (OHS), Obstructive Sleep Apnea (OSA)
Transdisciplinary Intervention for Obesity Hypoventilation Syndrome
The aims of this prospective observational cohort study are threefold: (1) to assess the prevalence of obesity hypoventilation syndrome (OHS) in individuals with obesity and obstructive sleep apnea (OSA) and identify associated…
- Trial name
- CABS for OHS (NCT07020689)
- Testing
- CABS
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Obstructive Sleep Apnea
Trazodone on OSA Endotypes
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive event and do not have time for…
- Trial name
- NCT06286189
- Testing
- Trazodone Hydrochloride
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea, Vascular Stiffness
CPAP to Reduce Arterial Stiffness in Non Sleepy, Moderate to Severe Obstructive Sleep Apnea (STIFFSLEEP)
This study intends to determine whether continuous positive airway pressure (CPAP) can reduce arterial stiffness (measured by pulse wave velocity) in nonsleepy as well as in sleepy patients with obstructive sleep apnea .
- Conditions
- Obstructive Sleep Apnea, Vascular Stiffness, Sleep Disorder Daytime Somnolence
- Trial name
- STIFFSLEEP (NCT02273089)
- Testing
- CPAP (ResMed S9 AutoSet)
- Where
- 2 sites in Portugal
- Volunteers
- 45 people
- Sponsor
- Centro Hospitalar de Lisboa Central
Childhood Obstructive Sleep Apnea Syndrome (OSAS)
Mechanism of Action of Fluticasone Furoate in Childhood Obstructive Sleep Apnea Syndrome
The purpose of this research is to find out how a nasal spray (fluticasone furoate), sometimes given to children with obstructive sleep apnea syndrome (OSAS), works on certain cells within a child's adenoids.
- Trial name
- NCT00603044
- Testing
- fluticasone furoate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Chicago
Obstructive Sleep Apnea (OSA)
Data Collection Study to Review Novel Methods for Diagnosing Obstructive Sleep Apnea
This study will collect data on a range of signals such as facial scans, videos (including speaking, blinking and swallowing) and heart rate variability to assess whether any of these measures are useful for diagnosing…
- Trial name
- Ignite (NCT06930404)
- Testing
- facial scans, videos and heart rate variability measurements
- Where
- Australia
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- ResMed
Obstructive Sleep Apnea
The Effect of Continuous Positive Airway Pressure on Diastolic Function in Patients With Obstructive Sleep Apnea
The association of obstructive sleep apnea (OSA) and cardiac diastolic dysfunction have been reported, and improvement of diastolic function after continuous positive airway pressure (CPAP) in OSA patients was observed.
- Trial name
- NCT01854398
- Testing
- CPAP group
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Obstructive Sleep Apnea (OSA)
Fractional Exhaled Nitric Oxide as Possible Non - Invasive Biomarker to Assess Obstructive Sleep Apnea Severity
Aim of work 1. Primary aim: Asses correlation between FeNO level, OSA severity 2. Secondary aim: Clarifying FeNO's role as a biomarker to assess airway inflammation, Cut off value prediction to moderate and severe OSA and its…
- Trial name
- NCT07606898
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Obstructive Sleep Apnea
Implant Supported Oral Appliance Treatment of OSA
Mandibular advancing oral appliances (OAm) are an effective and increasingly common treatment modality for the management of obstructive sleep apnea (OSA) in adults.
- Trial name
- BIMA (NCT03362671)
- Testing
- Implant Supported Mandibular Advancement Oral Appliance, Orthodontic Mini Implant
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of British Columbia
Obstructive Sleep Apnea
Structural and Functional Left Ventricular Remodelling in Patients With Obstructive Sleep Apnea
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in left ventricular function and structure after 06 months of continuous positive airway pressure treatment.
- Trial name
- NCT00768807
- Testing
- CPAP (continuous positive airway pressure)
- Where
- Brazil
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Sleep Apnea Syndromes, Snoring
Effects From a Mandibular Repositioning Appliance in Patients With Obstructive Sleep Apnea and Snoring
The purpose of this study is to evaluate effects from a mandibular repositioning appliance on obstructive sleep apneas, symptoms, blood pressure and markers of stress, inflammation and cardiovascular health in patients with mild…
- Conditions
- Sleep Apnea Syndromes, Snoring, Disorders of Excessive Somnolence
- Trial name
- NCT00477009
- Testing
- Mandibular repositioning appliance, adjustable
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Umeå University
Sarcoidosis, Sleep Apnea, Obstructive
Prevalence of Obstructive Sleep Apnea Syndrome in Sarcoidosis and Impact of CPAP Treatment on Associated Fatigue Status
Sarcoidosis is a multisystemic granulomatous disease that affects individuals worldwide without known pathogenesis, and the role of comorbidities has not been fully assessed in the scientific literature.
- Conditions
- Sarcoidosis, Sleep Apnea, Obstructive, Fatigue
- Trial name
- SARCOIDOSAS (NCT03926832)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sleep-Disordered Breathing, Chronic Opioid Use
Comprehensive Opioid Management and Breathing During Sleep
The REDUCE study will evaluate whether referral to a comprehensive opioid management program improves breathing stability during sleep in adults with chronic opioid use and sleep-disordered breathing.
- Trial name
- REDUCE (NCT07923721)
- Testing
- Comprehensive Opioid Management, Usual Care
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea, Sleep Disorder
Validation of Pediatric Sleep Questionnaire on a Swedish Cohort
This study is aimed to validate the questionnaire called Pediatric Sleep Questionnaire on a Swedish cohort of children from 18 months to 15 years old with obstructive sleep disordered breathing.
- Conditions
- Obstructive Sleep Apnea, Sleep Disorder, Sleep Disorders in Children, Obstructive Sleep Apnea of Child
- Trial name
- NCT06367400
- Testing
- Pediatric Sleep Questionnaire
- Where
- Sweden
- Volunteers
- 520 people
- Sponsor
- Uppsala University
Obstructive Sleep Apnea
The Impact of Venlafaxine on Apnea Hypopnea Index in Obstructive Sleep Apnea
The investigators hypothesis is that obstructive sleep apnea (OSA) patients with a low arousal threshold may wake up too early during a respiratory event, before upper airway muscles can be activated to achieve stable…
- Trial name
- NCT02714400
- Testing
- Venlafaxine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Sleep Apnea, Obstructive
Treatment Study of Soft Palatal Implants in Obstructive Sleep Apnea
The purpose of the study is to compare the effectiveness of soft palatal implants with placebo and continuous positive airway pressure treatment in obstructive sleep apnea.
- Trial name
- NCT00263770
- Testing
- soft palate implant, Positive airway pressure (PAP)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Mayo Clinic
Normotensive, Sleep Apnea, Obstructive
Normotensive OSA Patients With Dipper Circadian Blood Pressure Pattern
The principal objective is to evaluate the effect of CPAP treatment on blood pressure (BP) in normotensive patients with dipper circadian pattern with sleep apnea-hypopnea syndrome (SAHS).
- Trial name
- NCT03948373
- Testing
- CPAP treatment
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
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