Clinical trials: Sleep Apnea Syndrome (OSAS)
Comorbid Insomnia and Sleep Apnea, Insomnia
Wearable Voice-Guided BBTi for Comorbid Insomnia and Sleep Apnea (COMISA)
This study investigates the efficacy of a wearable voice-guided Brief Behavioral Therapy for Insomnia (BBTi) combined with a smart eye-mask device for individuals with Comorbid Insomnia and Sleep Apnea (COMISA).
- Conditions
- Comorbid Insomnia and Sleep Apnea, Insomnia, Obstructive Sleep Apnea
- Trial name
- BBTi-COMISA (NCT07521319)
- Testing
- Brief Behavioral Therapy for Insomnia (BBTi), Smart Eye-Mask with Voice-Guided Modules
- Where
- Taiwan
- Volunteers
- 361 people
- Sponsor
- National Sun Yat-sen University
Obstructive Sleep Apnea
Humidification Needs
A study undertaken to investigate mouth leak for airway discomfort/dryness while using CPAP. This study will also measure how much humidification is required to treat subsequent upper airway discomfort/dryness from mouth leak by…
- Trial name
- NCT03247907
- Testing
- Condition A: CPAP with No Humidification, Condition B: CPAP with No Humidification, Condition C: CPAP with Cold Passover
- Where
- New Zealand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fisher and Paykel Healthcare
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
The Impact of Obstructive Sleep Apnoea in Women With Polycystic Ovary Syndrome.
Women with PCOS and OSA, compared to women with PCOS only, have more severe clinical and biochemical features of PCOS and impaired QoL.
- Trial name
- NCT03065322
- Testing
- To assess risk of OSA
- Where
- United Kingdom
- Volunteers
- 38 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Hypertension, Blood Pressure
Feasibility and Effectiveness of a Ring-type Blood Pressure Measurement Device
The goal of this clinical trial is to evaluate the feasibility and effectiveness of a ring-type blood pressure measurement device compared to a 24-hour ambulatory blood pressure monitoring device in patients with hypertension or…
- Conditions
- Hypertension, Blood Pressure, Systolic Hypertension, Diastolic Hypertension
- Trial name
- NCT06084065
- Testing
- CART-I Plus
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Obstructive Sleep Apnea, Sleep Disorder (Disorder)
Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation
Atrial fibrillation (AF) is one of the most common clinical arrhythmias. Catheter ablation is an effective therapeutic strategy; however, recurrence rates remain substantial, ranging from 20% to 45%.
- Conditions
- Obstructive Sleep Apnea, Sleep Disorder (Disorder), Atrial Fibrillation (AF), Sleep Disordered Breathing (SDB)
- Trial name
- STOP-AFib (NCT07444372)
- Testing
- Continuous Positive Airway Pressure (CPAP), Usual Care
- Where
- 30 sites in China
- Volunteers
- 658 people
- Sponsor
- Beijing Anzhen Hospital
Sleep Apnea, Obstructive
Obstructive Sleep Apnea - Patient Specific Factors, Success Rate and Compliance
Obstructive sleep apnea (OSA) is a condition where the patient's breathing cease during sleep due to collapse of the oro-pharynx.
- Trial name
- NCT02953028
- Testing
- CPAP, Mandibular Advancing Splint
- Where
- 2 sites in Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
Sleep-disordered Breathing, Sleep Apnea, Obstructive
Behavioral Effects of Obstructive Sleep Apnea in Children
Sleep-disordered breathing (SDB) in children may be responsible for disruptive daytime behaviors such as inattention and hyperactivity. Many children undergo tonsillectomy for SDB and disruptive daytime behaviors.
- Conditions
- Sleep-disordered Breathing, Sleep Apnea, Obstructive, ADHD
- Trial name
- NCT00060723
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obstructive Sleep Apnea, Neurocognitive Disorders
Postoperative Neurocognitive Disorders
The purpose of this study is to examine the mechanisms of brain injury contributing to postoperative neurocognitive disorders (PNCD) in an at-risk population (obstructive sleep apnea (OSA)) undergoing surgery.
- Trial name
- PNCD (NCT04244162)
- Testing
- Brain Imaging, Cognitive testing, Blood Biomarkers
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital
Obstructive Sleep Apnea, Comorbid Insomnia and Sleep Apnea
Does the Timing of Insomnia Therapy (CBT-i) Impact the Usage and Compliance of Upper Airway Stimulation (UAS) Treatment of Obstructive Sleep Apnea (OSA)
Obstructive sleep apnea, or OSA, affects over 1 billion adults worldwide. OSA is one of many sleep disorders. Individuals can suffer from more than one sleep disorder at a time.
- Conditions
- Obstructive Sleep Apnea, Comorbid Insomnia and Sleep Apnea, Insomnia
- Trial name
- CBT-i and UAS (NCT07838870)
- Testing
- Digital Cognitive Behavioral Therapy (CBT-i)-COAST
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Thomas Kaffenberger
Obstructive Sleep Apnea, Surgery
Mini-dose Dexmedetomidine-Esketamine Supplemented Analgesia in Patients at High-risk of OSA
Patients with obstructive sleep apnea (OSA) are at increased risk of developing sleep disturbances after surgery. Dexmedetomidine is a highly selective α2-adrenergic agonist with sedative, analgesic, and anxiolytic effects.
- Conditions
- Obstructive Sleep Apnea, Surgery, Dexmedetomidine, Esketamine
- Trial name
- NCT06566482
- Testing
- Dexmedetomidine-esketamine combination
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University First Hospital
Obstructive Sleep Apnea
Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype
The primary objective of this study is to determine the longer-term (6 months) effect of CPAP therapy on change in 24-hour mean blood pressure (24hMBP) in OSA subjects with the excessively sleepy symptom subtype.
- Trial name
- NCT05742360
- Testing
- CPAP therapy
- Where
- 2 sites in United States
- Volunteers
- 227 people
- Sponsor
- Ohio State University
Obstructive Sleep Apnea
Stimulation Therapy for Apnea Reduction (Www.theSTARtrial.Com)
The purpose of this clinical trial is to demonstrate long-term safety and efficacy of the Inspire system. The Inspire Upper Airway Stimulation (UAS) therapy is intended to treat moderate-to-severe obstructive sleep apnea by…
- Trial name
- STAR (NCT01161420)
- Testing
- Inspire Upper Airway Stimulation System
- Where
- 22 sites in United States, Belgium and 3 more
- Volunteers
- 929 people
- Sponsor
- Inspire Medical Systems, Inc.
Obstructive Sleep Apnea of Adult, Difficult or Failed Intubation
Changes in Difficult Airway Markers After Surgery for Obstructive Sleep Apnoea Syndrome
This study investigates the changes in difficult airway markers at 6 months post operatively in patients undergoing obstructive sleep apnoea surgery
- Trial name
- NCT06447818
- Testing
- Change in airway markers
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Kocaeli City Hospital
Memory Deficit
Protocol Memory Deficit in Patients With Obstructive Sleep Apnea Syndrome
The main objective of this study is to evaluate the evolution of memory deficit (verbal episodic memory, procedural memory, working memory, short-term memory) in Sleep Apnea Obstructive Syndrome (SAOS) patients after treatment by…
- Trial name
- NCT00464659
- Testing
- Effective CPAP
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Pregnancy Related
Prevalence Study and Identification of Factors Prognosis of Obstructive Sleep Apnea Syndrome Sleep in Pregnant Women
The exact prevalence of sleep-disordered breathing in pregnant women is not known. The results of a analysis of a small cohort of 105 pregnant women adjusted to body mass index estimate a prevalence of 8.4% in first quarter and…
- Trial name
- SAOSPRONOS (NCT05725642)
- Testing
- Polysomnography
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Sleep Apnea - Obstructive
A Study of the Sleepnet Elara APAP Device
The goal of this study is to evaluate the effectiveness of the Elara APAP device.
- Trial name
- NCT07559708
- Testing
- Sleepnet Elara Treatment
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Sleepnet Corporation
Sleep Apnea, Obstructive, Pregnancy
OSA in Pregnant Women With Chronic HTN
The purpose of this study is to identify whether pregnant women with chronic hypertension are at significantly higher risk of having undiagnosed OSA and should be routinely screened with home sleep tests.
- Conditions
- Sleep Apnea, Obstructive, Pregnancy, Hypertension
- Trial name
- OSA-CHTN (NCT03230110)
- Testing
- WP200U home sleep study device
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Duke University
Obstructive Sleep Apnea
Inspire® Upper Airway Stimulation (UAS) System German Post-Market Study
The purpose of this study is to obtain additional safety and efficacy data on the use of Inspire® therapy for the treatment of subjects with moderate to severe Obstructive Sleep Apnea.
- Trial name
- NCT02293746
- Testing
- Inspire® Upper Airway Stimulation (UAS) System
- Where
- 3 sites in Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inspire Medical Systems, Inc.
Asthma (Diagnosis), OSA - Obstructive Sleep Apnea
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
The OSADA (Obstructive Sleep Apnoea in Difficult Asthma) trial is an open-label, randomized control trial investigating the impact of diagnosing and treating obstructive sleep apnoea (OSA) on a asthma control in patients with…
- Conditions
- Asthma (Diagnosis), OSA - Obstructive Sleep Apnea, CPAP Treatment
- Trial name
- OSADA (NCT07160868)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- St. James's Hospital, Ireland
Obstructive Sleep Apnea, Hypopnea Syndrome
Retinal Nerve Fiber Layer Thickness Measurements in Patients With Sleep Apnea Syndrome
The purpose of this study was to measure the retinal nerve fiber layer (RNFL) thickness in eyes of Obstructive Sleep Apnea/hypopnea syndrome (OSAHS) using optical coherence tomography (OCT), and assess whether it is decreased.
- Conditions
- Obstructive Sleep Apnea, Hypopnea Syndrome, Glaucoma
- Trial name
- NCT01188291
- Where
- Israel
- Volunteers
- 166 people
- Sponsor
- Carmel Medical Center