Clinical trials: Sleep Apnea Syndromes, Obstructive
Obstructive Sleep Apnea
Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea
This research study is designed to learn, first, whether two anesthetics have different effects on collapse seen within the upper airway during sleep endoscopy.
- Trial name
- NCT05303987
- Testing
- Propofol sedation, Dexmedetomidine sedation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Erin Kirkham
Afib, Sleep Apnea Syndrome, Obstructive
Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):
A pilot N-of-1 randomized controlled trial evaluating the effectiveness of a personalized CPAP intervention in reducing atrial fibrillation (AF) burden and improving AF-related quality of life in patients with moderate to severe…
- Conditions
- Afib, Sleep Apnea Syndrome, Obstructive, CPAP
- Trial name
- SPARTA (NCT07087587)
- Testing
- CPAP
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Sleep Apnea, Obstructive
Compliance With Continuous Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea Syndrome
The aim of the study is to know the adherence to treatment and compliance of patients diagnosed with SAHS and with indication of CPAP from the sleep unit of the Hospital de Sabadell.
- Trial name
- CPAPSH (NCT03776084)
- Testing
- Continuous Positive Airway Pressure
- Where
- Spain
- Volunteers
- 405 people
- Sponsor
- Corporacion Parc Tauli
Obstructive Sleep Apnea, Overhydration
Effect of Intermittent Hemodialysis on Sleep Apnea Syndrome in End Stage Renal Disease Patients
The purpose of this study is to investigate the effect of decreasing fluid overload by hemodialysis on the severity of obstructive sleep apnea, in patients with end stage chronic kidney disease on intermittent hemodialysis.
- Conditions
- Obstructive Sleep Apnea, Overhydration, End Stage Renal Disease
- Trial name
- SASinHD (NCT01860209)
- Testing
- Hemodialysis
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
OSA, Adherence, Patient
Adherence to CPAP in Patients With OSA. Ten Year Follow up
The management of OSA is aimed to improve symptoms and mitigate reduce other health consequences. Continuous Positive Airway Pressure (CPAP) is the recognized treatment for OSA, able to reverse the pathophysiology of OSA and…
- Conditions
- OSA, Adherence, Patient, CPAP
- Trial name
- NCT03644121
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Maugeri Foundation
Obstructive Sleep Apnea
Ultrasound Against Obstructive Sleep Apnea
To investigate the accuracy of neck ultrasound in identifying and discriminating the severity of obstructive sleep apnea (OSA). Primary objective: To test the hypothesis that ultrasound can be used as a reliable tool for…
- Trial name
- NCT02788149
- Testing
- Ultrasound Exam, Polysomnography
- Where
- United States
- Sponsor
- Henry Ford Health System
Diabetes Mellitus, Periodontal Diseases
Periodontitis as Signal for an Underlying Disease
This study investigates the differences between subjects with and without periodontitis in: the prevalence of (pre)diabetes mellitus, the risk of atherosclerotic cardiovascular disease, the prevalence of metabolic syndrome and…
- Conditions
- Diabetes Mellitus, Periodontal Diseases, Cardiovascular Diseases, Obstructive Sleep Apnea Syndrome
- Trial name
- PACMEL (NCT03459638)
- Testing
- Screening for DM, ASCVD, MetS and OSAS
- Where
- Netherlands
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Academic Centre for Dentistry in Amsterdam
Sleep Apnea Syndromes in Children, Functional Orthodontic Treatment
Evaluation of Functional Orthodontic Treatment on Sleep Quality
Functional appliances are used in the treatment of Class II anomalies caused by mandibular rethrognathia. Herbst which is a fixed and rigid functional appliance and TWB which is removable appliance can be successful in the…
- Conditions
- Sleep Apnea Syndromes in Children, Functional Orthodontic Treatment, Mandibular Retrognathia, Upper Airway
- Trial name
- NCT06660771
- Testing
- Functional orthodontic treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Gökçenur Gökçe Kara
Transient Global Amnesia
PRevalence Of Transient Global Amnesia in Obstructive Sleep Apnea Syndrome
Amnesic stroke is an amnestic syndrome lasting less than 24 hours characterized by the occurrence of anterograde amnesia often associated with retrograde amnesia, the pathophysiology of which is still poorly understood at…
- Trial name
- PROTOS (NCT06903026)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Strasbourg, France
Observation
Influence of Craniofacial Restriction on Rebound of Obstructive Sleep Apnea Following Weight Gain
Apart from obesity, craniofacial factors are well recognized in the pathogenesis of obstructive sleep apnea (OSA) and are likely to play an important role in influencing the response to weight loss.
- Trial name
- NCT03051815
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Sleep Apnea, Obstructive
A Trial to Learn More About How Well BAY2586116 Works and How Safe it is in Participants With Moderate to Severe Obstructive Sleep Apnea
Researchers are looking for a better way to treat people with obstructive sleep apnea (OSA). In people with OSA, the upper airways can narrow or close repetitively while sleeping.
- Trial name
- SPRAY-SMART (NCT04713826)
- Testing
- BAY2586116
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 93 people
- Sponsor
- Bayer
Asthma (Diagnosis), OSA - Obstructive Sleep Apnea
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
The OSADA (Obstructive Sleep Apnoea in Difficult Asthma) trial is an open-label, randomized control trial investigating the impact of diagnosing and treating obstructive sleep apnoea (OSA) on a asthma control in patients with…
- Conditions
- Asthma (Diagnosis), OSA - Obstructive Sleep Apnea, CPAP Treatment
- Trial name
- OSADA (NCT07160868)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- St. James's Hospital, Ireland
Obstructive Sleep Apnea, Adherence, Patient
Increasing Adherence to Oral Appliance Therapy for Obstructive Sleep Apnea
Obstructive sleep apnea is a chronic condition that has serious health consequences including increased risk of hypertension, type-2 diabetes, heart disease, stroke and reduced life expectancy.
- Trial name
- NCT05038215
- Testing
- adherence promotion techniques, Routine Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Ohio State University
Obstructive Sleep Apnoea (OSA)
Breath Analysis in Obstructive Sleep Apnoea
Clinical trial in patients with obstructive sleep apnoea that are randomised to either continue or withdraw continuous positive airway pressure therapy to identify a disease-specific exhaled breath pattern by mass spectrometry.
- Trial name
- NCT02050425
- Testing
- CPAP
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Obstructive Sleep Apnea Syndrome
Trained Patient Involvement to Promote the Resumption of CPAP in Patients Who Have Discontinued Its Use
The primary objective of this randomized clinical trial is to evaluate the role of patient researchers in promoting the resumption of CPAP therapy in apneic patients who had previously stopped CPAP
- Trial name
- NCT04538274
- Testing
- peer-driven intervention
- Volunteers
- 208 people
- Sponsor
- AGIR à Dom
Obstructive Sleep Apnea (Mild, Moderate, Severe) as Per Polysomnography
Intranasal Mometasone in Children With Obstructive Sleep Apnea Due to Adenotonsillar Hypertrophy
Obstructive sleep apnea (OSA) in children is a disorder of breathing during sleep characterized by prolonged partial upper airway obstruction and/or intermittent complete obstruction (obstructive apnea) that disrupts normal…
- Trial name
- Nasonex OSA (NCT01671852)
- Testing
- Mometasone furoate nasal spray
- Where
- Canada
- Sponsor
- Children's & Women's Health Centre of British Columbia
Sleep Apnea, Metabolic Syndrome
Improving the STOP-Bang Screening Questionnaire for Patients With Sleep Apnea
The study is being conducted to test the ability of a simple questionnaire to detect mild, moderate or severe obstructive sleep apnea.
- Trial name
- NCT01610648
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Tufts Medical Center
Obstructive Sleep Apnea
Telemedici ne Management of Veterans With Newly Diagnosed Obstructiv e Sleep Apnea (OSA)
Automatically titrating continuous positive airway pressure (APAP) and continuous positive airway pressure (CPAP) are considered first-line treatments for obstructive sleep apnea.
- Trial name
- NCT02159885
- Testing
- Telemonitoring
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Corporal Michael J. Crescenz VA Medical Center
Ventilator-Induced Lung Injury
Intraop Ventilation Management and Postop Pulmonary Complications in High Risk Patients for OSA
Lung protective ventilation (LPV) has been proposed to reduce the incidence of postoperative pulmonary complications (PPCs), and protect against ventilator induced lung injury (VILI).
- Trial name
- NCT03135691
- Where
- United States
- Sponsor
- Ohio State University
Obstructive Sleep Apnea
Asthma Outcomes in Children After Adenotonsillectomy
The aim of the study is to assess the effect of adenotonsillectomy on level of asthma control in preschool children with obstructive sleep apnea.
- Trial name
- NCT03842618
- Volunteers
- 60 people
- Sponsor
- Assiut University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.