Clinical trials: Sleep Apnea Syndromes, Obstructive
Sleep Apnea, Sleep Apnea, Obstructive
Evaluation of the Effects of Hypoglossal Nerve Stimulation in Humans With Obstructive Sleep Apnea
This proof-of-concept study is being performed to evaluate whether the hypoglossal nerve can be stimulated using a small series of electrodes placed surgically via a percutaneous approach.
- Conditions
- Sleep Apnea, Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes
- Trial name
- NCT06283017
- Testing
- Hypoglossal nerve stimulation
- Where
- Australia
- Volunteers
- 14 people
- Sponsor
- Invicta Medical Inc.
Obstructive Sleep Apnoea, Obesity
Peripheral Vascular Function in Obstructive Sleep Apnoea
Peripheral vascular function is impaired in people with obstructive sleep apnoea who are untreated compared with age-, weight- and sex-matched healthy controls.
- Trial name
- NCT01619748
- Where
- 2 sites in United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Sleep Apnea Syndromes, Sleep Apnea, Obstructive
Targeted Hypoglossal Neurostimulation Study #2
The objective of the study is to confirm the safety and efficacy in patients utilizing the aura6000 System for the treatment of Obstructive Sleep Apnea (OSA).
- Conditions
- Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Respiration Disorders, Signs and Symptoms, Respiratory
- Trial name
- THN2 (NCT01796925)
- Testing
- aura6000 THN System
- Where
- 9 sites in United States, Belgium and 3 more
- Volunteers
- 57 people
- Sponsor
- ImThera Medical, Inc.
Obstructive Sleep Apnea
Improving the Efficiency of the Digital Sleep Workflow Using MATRx Plus
Sleep apnea (OSA) is a condition in which the air passage in the throat closes or partly closes during sleep and repeatedly interrupts breathing.
- Trial name
- NCT03579225
- Testing
- MATRx plus test
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Zephyr Sleep Technologies
Obstructive Sleep Apnea
Use of Blood Biomarkers and Biomarker Index to Aid in the Diagnosis of Obstructive Sleep Apnea (OSA)
This multicenter prospective trial will evaluate the association between obstructive sleep apnea (OSA) and blood biomarkers in a representative population of consecutively enrolled symptomatic patients with a clinical suspicion…
- Trial name
- NCT03122483
- Testing
- blood biomarker
- Where
- 3 sites in United States
- Volunteers
- 250 people
- Sponsor
- Beckman Coulter, Inc.
Obstructive Sleep Apnea
Developement of TipTraQ Home Sleep Test
The clinical study aims to develop and fine-tune the TipTraQ system, created by PranaQ, for home sleep apnea screening. The system comprises a wearable device and a cloud-based AI for estimating Total Sleep Time (TST) and…
- Trial name
- NCT06474351
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- PranaQ Pte. Ltd.
Pediatric Obstructive Sleep Apnea, Pediatric Obesity
Treating Children With Obstructive Sleep Apnea After Surgery Failure
The aim of this study is to evaluate the potential improvement of sleep quality in children who have residual obstructive sleep apnea, using either an orthodontic intervention or continuous positive airway pressure (CPAP), versus…
- Trial name
- NCT03821831
- Testing
- Continuous Positive Airway Pressure, Orthodontic intervention
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Alberta
Obstructive Sleep Apnea
Evaluation of Post-surgical Improvement in OSA Patients After Imaging of Upper Airway Using CBCT and DISE vs DISE Only
CBCT is considered an innovative imaging modality that can view the upper respiratory airway anatomy in a 3D manner. Recent studies tried to evaluate the accuracy of CBCT in analyzing the upper respiratory airway and its related…
- Trial name
- NCT04727346
- Testing
- CBCT, DISE
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sleep-disordered Breathing (SDB), Aortic Valve Stenosis
Impact of Transcatheter Aortic Valve Implantation and Mitral Valve Repair on Sleep-Disordered Breathing
This prospective observational study aims to investigate the impact of transcatheter aortic valve implantation (TAVI) and transcatheter mitral valve edge-to-edge repair (M-TEER) on sleep-disordered breathing (SDB) in patients…
- Conditions
- Sleep-disordered Breathing (SDB), Aortic Valve Stenosis, Mitral Valve Regurgitation
- Trial name
- SLEEP-VALVE (NCT07520656)
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Aristides Plaitis
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
In this study, the researchers are trying to learn more about the relationship between Polycystic Ovary Syndrome and Obstructive Sleep Apnea (OSA).
- Trial name
- NCT05920694
- Testing
- Continuous Positive Airway Pressure Device (CPAP), Delayed Continuous Positive Airway Pressure Device (CPAP)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Obstructive Sleep Apnea
Unrecognised Obstructive Sleep Apnea Study
Plan of investigation: This is an observational cohort study to determine the effect of OSA, independent of other risk factors, on postoperative vascular events.
- Trial name
- OSA (NCT01494181)
- Where
- 4 sites in Canada, Hong Kong and 2 more
- Volunteers
- 1,200 people
- Sponsor
- University Health Network, Toronto
Sleep Apnea
Telemedicine Interventions for Obstructive Sleep Apnea (OSA)
This project is investigating whether both moderate-intensity physical activity and dietary weight loss will independently reduce sleep apnea symptoms and improve quality of life.
- Trial name
- NCT01108081
- Testing
- Physical activity, Diet, Health education
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea, Obstructive Sleep Apnea
Effect on Sleep of Surgical Treatment of Severe Nasal Obstruction
The aim of the study is to evaluate the effect of nasal desobstruction surgery (septoplasty, septorhinoplasty or total ethmoidectomy) on sleep quality, assessed by the variation of the Wake after sleep onset (WASO), in patients…
- Conditions
- Sleep Apnea, Obstructive Sleep Apnea, Nasal Obstruction
- Trial name
- SOMNOSE (NCT05582070)
- Testing
- actigraphy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Sleep Apnea, Obstructive
The Phenotyping and Genotyping of Taiwanese Patients With Obstructive Sleep Apnea
The growing evidence showed that the OSA is a heritable complex genetic disease where the genetic basis contributed the development of OSA and its sequel. The phenotyping of OSA include high level and intermediate level.
- Trial name
- NCT02038751
- Where
- Taiwan
- Volunteers
- 360 people
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnea
Efficacy of High Flow Nasal Oxygen During Sleep Endoscopy in Patients of Obstructive Sleep Apnea
The purpose of this study is to investigate the utility of high-flow nasal oxygen during sleep endoscopy in obstructive sleep apnea patients.
- Trial name
- NCT03777202
- Testing
- High-flow nasal oxygen, Low-flow nasal oxygen
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Yonsei University
Obstructive Sleep Apnea
Pediatric Post-Approval Registry
This registry is a prospective, multi-center, single-arm study of pediatric subjects (ages 18-21 years) who are undergoing implant of the Inspire Upper Airway Stimulation (UAS) System for the treatment of moderate or severe…
- Trial name
- NCT04457154
- Testing
- Inspire Upper Airway Stimulation System
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- Inspire Medical Systems, Inc.
Obstructive Sleep Apnea Hypopnea Syndrome
Comparison of the SUNRISE© Device With Ventilatory Polygraphy for the Diagnosis of Obstructive Sleep Apnea Hypopnea Syndrome: Collection of Preliminary Data
Additional data on screening for obstructive sleep apnea/hypopnea syndrome (OSAHS) in patients with co-morbidities, such as diabetics and those with chronic respiratory diseases would enable current recommendations to evolve…
- Trial name
- SUNPV (NCT06460441)
- Testing
- SUNRISE© device
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Sleep Apnea, Obstructive
Adherence to Continuous Positive Airway Pressure Among Obstructive Sleep Apnoea Patients.
Prospective study designed to identify factors that would predict patient adherence to CPAP (Continuous Positive Airway Pressure) therapy.
- Trial name
- NCT02055027
- Testing
- Comparison between groups
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Astes
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Prospective Study to Evaluate Outcomes From Transoral BOT Resection for OSAHS
This is a prospective observational study that will collect outcome data for patients who choose to undergo transoral tongue base operations for Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)as part of their standard of care…
- Trial name
- NCT01107795
- Testing
- Transoral Robotic Surgery
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Alabama at Birmingham
Obstructive Sleep Apnea Syndrome, Brain Infarction
Consequences of Obstructive Sleep Apnea Syndrome (OSAS) After Ischemic Subtentorial Stroke.
Obstructive Sleep Apnea Syndrome (OSAS) is associated with stroke as a risk factor but little is known about the consequences of OSAS on the outcome and the survival after stroke.
- Trial name
- NCT01561677
- Testing
- Continuous Positive Airway pressure-RESPIRONICS
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
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