Clinical trials: Sleep Apnea Syndromes
Sleep Apnea - Obstructive
A Study of the Sleepnet Elara APAP Device
The goal of this study is to evaluate the effectiveness of the Elara APAP device.
- Trial name
- NCT07559708
- Testing
- Sleepnet Elara Treatment
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Sleepnet Corporation
Sleep Apnea
Phenotypic Characteristics of Responders to Obstructive Sleep Apnea Treatment Using Mandibular Advancement Devices
Currently, mandibular advancement devices (MAD) are recommended by the American Academy of Sleep Medicine (AASM) as the first treatment a line in cases of mild and moderate OSAS in patients without severe cardiovascular…
- Trial name
- NCT05596825
- Testing
- Mandibular Advancement Device
- Volunteers
- 75 people
- Sponsor
- University of Valencia
Lung Diseases, Sleep Apnea Syndromes
Prevalence of Sleep-Disordered Breathing in Children
To investigate the prevalence and clinical significance of sleep-disordered breathing (SDB) in children.
- Trial name
- NCT00022789
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Milton S. Hershey Medical Center
Sleep Disordered Breathing, Sleep Apnea, Central
Evaluation of the Philips Respironics BiPAP autoSV Devices in Subjects With Sleep Disorders
Comparing two BiPAP autoSV devices in participants with complex sleep apnea and determining if the new device will treat those participants no worse than when compared to its predecessor device.
- Trial name
- NCT01626989
- Testing
- BiPAP auto Advanced, BiPAP auto SV4
- Where
- 3 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Philips Respironics
Neuromuscular Disorders
Screening Questionnaire for Respiratory Muscle Weakness and Sleep-disordered Breathing in Neuromuscular Disorders
It is the aim of this project to develop and validate a German language screening questionnaire for symptoms of respiratory muscle weakness and sleep-disordered breathing (SDB) in patients with neuromuscular disorders.
- Trial name
- NCT02833168
- Testing
- patient-filled questionnaires, spiromanometry
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Universität Münster
Obstructive Sleep Apnea, Obesity
Effect of Nasal Positive Airway Pressure Versus Standard Care on Oxygenation and Ventilation During Propofol-based Sedation for Colonoscopy in Patients With High Risk of Airway Obstruction
The purpose of this study is to to compare oxygenation and ventilation on spontaneously ventilating obese patients or those with diagnosed or undiagnosed Obstructive sleep apnea (OSA) undergoing day colonoscopy under Propofol…
- Trial name
- NCT05524220
- Testing
- Standard care with a facemask., SuperNO2VA™EtCO2 (Nasal Oxygenating Ventilating Apparatus)
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- The University of Texas Health Science Center, Houston
Sleep Apnoea, Obstructive Sleep Apnoea
Developing a Non-contact Sleep Apnoea Detector, Suitable for Home Studies- The Safescan Study
Sleep apnoea (SA) is a common condition in adults and children that causes disturbed sleep and daytime symptoms. It is characterised by disrupted breathing with disturbed sleep patterns.
- Trial name
- NCT04071860
- Where
- United Kingdom
- Volunteers
- 445 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Obstructive Sleep Apnea
The Evaluation of a Nasal Pillows Mask for the Treatment of Obstructive Sleep Apnea (OSA) in NZ
This investigation is designed to evaluate the performance (leak and comfort) as well as the participant's overall acceptance of the nasal pillows mask amongst Obstructive Sleep Apnea (OSA) participants.
- Trial name
- NCT02741635
- Testing
- New Nasal Pillows Mask
- Where
- New Zealand
- Volunteers
- 15 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Field Usability Study of Eclipse Mask
The study is designed to assess the usability of a novel CPAP human interface compared to a traditional nasal mask. Human subjects will interact with two different CPAP interfaces including a traditional CPAP mask and the 2nd…
- Trial name
- NCT05559047
- Testing
- Eclipse mask
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bleep, LLC
Obstructive Sleep Apnea (OSA)
DAW2020 on OSA Endotypic Traits
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. Some OSA patients with low arousal threshold wake up prematurely during an obstructive event and do not have time for…
- Trial name
- SedOSA (NCT04538755)
- Testing
- DAW2020 oral capsule
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Sleep Disorders, Sleep Apnea, Obstructive
Sleep Disorders Management, Health and Safety in Police
The purpose of the study is to test the effect of a sleep disorders detection and treatment program for police officers on their safety, quality of life, and job performance. The program is called Operation Healthy Sleep.
- Conditions
- Sleep Disorders, Sleep Apnea, Obstructive, Restless Legs Syndrome, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT00207285
- Testing
- Sleep Hygiene Education, Screening and Treatment of Sleep Disorders
- Where
- United States
- Volunteers
- 731 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Spinal Cord Injuries, Spine Disease
Outcomes Post Treatment: Impact on Motor Impairment of Sleep Efficiency in SCI (OPTIMISE SCI Trial)
This randomized clinical trial will compare three groups of individuals with cervical/thoracic, complete or incomplete spinal cord injury (SCI) that will undergo: (i) early CPAP therapy in the management of moderate-to-severe…
- Trial name
- NCT05473689
- Testing
- Continuous positive airway pressure (CPAP) therapy
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University Health Network, Toronto
Obstructive Sleep Apnea
Exercise Intolerance in Obstructive Sleep Apnea Syndrome Patients
The syndrome of obstructive sleep apnea (OSAS) is a public health problem that affects 2 to 4% of the general population. The patients with OSAS frequently complain of intolerance to exercise muscle fatigue and a significant even…
- Trial name
- EXAOS (NCT00837018)
- Testing
- physical exercise program
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Sleep Apnea Syndromes
Comparison of Sleep Disordered Breathing Events Detected by the CPAP Device "prismaLine" With Polysomnography
Evaluation of residual sleep disordered breathing (SDB) under continuous positive airway pressure (CPAP) therapy with comparison of the automatic detected SDB event indices from CPAP machines with manual scored polysomnography…
- Trial name
- NCT04407949
- Testing
- CPAP Treatment
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Institut für Pneumologie Hagen Ambrock eV
Sleep Apnea, Obstructive
Cardiovascular Variability and Heart Rate Response Associated With Obstructive Sleep Apnea
Obstructive sleep apnea is often associated with microarousals and a stimulation of the sympathetic nervous system. The knowledge of this autonomic activation may help understanding the increase of cardiac risk observed in…
- Trial name
- OSAS (NCT03075787)
- Testing
- standard 24-h ambulatory polysomnography
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Insulin Sensitivity, Obstructive Sleep Apnea
Obesity, Sleep Apnea, and Insulin Resistance
Obstructive sleep apnea (OSA) and type 2 diabetes confer increasing economic, social, and public health burdens in the United States.
- Trial name
- NCT02192684
- Testing
- Pioglitazone
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obstructive Sleep Apnoea
Efficacy of PAP Therapy on Blood Pressure
The aim of the study was to determine the long term effects of compliance with positive airway pressure therapy on blood pressure in both hypertensive and normotensive patients with obstructive sleep apnoea hypopnoea syndrome.
- Trial name
- NCT02417584
- Testing
- positive airway pressure (PAP)
- Where
- Greece
- Volunteers
- 1,168 people, healthy volunteers welcome
- Sponsor
- University of Crete
Sleep Apnea, Obstructive, Chronic Obstructive Pulmonary Disease
Integrated Management of Chronic Respiratory Diseases
Chronic respiratory diseases such as obstructive sleep apnea syndrome (OSA) and chronic obstructive pulmonary disease (COPD) constitute a major public health problem, due to their high prevalence, but especially because of their…
- Trial name
- eMEUSE-SANTE (NCT04963192)
- Testing
- Connected actimeter to measure physical activity in OSA patients, Connected BORA Band to measure physical activity in COPD patients only, IPAQ to evaluated physical activity
- Where
- 2 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea, Obesity
The Relationship Between Obesity-related Molecular Typing and Traditional Chinese Medicine Constitution
Obesity is an epidemic and a growing problem in the world. There are numerous causes of obesity, the most novel and personalized of which is genetic inheritance.
- Trial name
- NCT04326244
- Testing
- blood test, genetic test, Constitution in Chinese Medicine Questionnaire
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
Sleep Apnea
Sleep Apnea in Acromegaly After Surgery
Sleep apnea is common in acromegaly and both diseases are independently associated with hypertension and insulin resistance contributing to increased morbidity and mortality.
- Trial name
- NCT03526016
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital