Clinical trials: Sleep Apnea Syndromes in Children
Obstructive Sleep Apnea Syndrome
Didgeridoo Treatment to Improve Pharyngeal Compliance in Obstructive Sleep Apnea-hypopnea Syndrome in Children
The therapeutic management of Obstructive Sleep Apnoea Syndrome in children remains a debated subject, only otorhinolaryngology surgery (adenoidectomy) has been studied on a large scale.
- Trial name
- SASDICO (NCT05164211)
- Testing
- Didgeridoo
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obstructive Sleep Apnea Hypopnea Syndrome
Feasibility in Every Day Pratice in an ENT Department and Value of the Automatic Detection of Respiratory Events
The use of respiratory polygraphy (RP) in children for the diagnosis of obstructive sleep apnea hypopnea syndrome (OSAHS) can be challenging: device acceptance, sensors displacement.
- Trial name
- NCT03817762
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Montpellier
Cleft Palate
Sleep and Behavior in Children With Cleft Palate
The purpose of this study is to determine whether cleft palate repair increases the risk for obstructive sleep apnea in children and whether sleep apnea could explain learning and behavior difficulties that are often observed.
- Trial name
- NCT01046591
- Testing
- Polysomnography
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cerebral Palsy (CP), Sleep Disordered Breathing (SDB)
Epidemiology of Sleep Disordered Breathing in Children and Young People With Cerebral Palsy
Cerebral palsy (CP) refers to a non-progressive movement disorder, which occurs due to damage to the developing brain around the time of birth.
- Conditions
- Cerebral Palsy (CP), Sleep Disordered Breathing (SDB), Respiratory Support
- Trial name
- UK_CPSSS (NCT06737302)
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Edinburgh
Sleep Disordered Breathing (SDB), Endothelial Dysfunction
Sleep Disordered Breathing in Children: Inflammation and Oxidative Stress
The purpose of the study is to measure markers of inflammatory and oxidative stress known to be associated with cardiovascular morbidity in snoring children.
- Trial name
- NCT02040701
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obstructive Sleep Apnea, Difficult Airway
Airway Ultrasound Prediction and Correlation
This is a novel approach to assess the use of ultrasound to support the identification of obstructive sleep apnea syndrome (OSAS) on a screening questionnaire, and potentially to predict a difficult pediatric airway.
- Trial name
- NCT03313947
- Testing
- Ultrasound, Questionnaire
- Where
- United States
- Sponsor
- Vidya Raman
Pediatric Sleep Apnea, Obesity
Sleep Apnea and Obesity Affects on Morphine Pharmacokinetics
Adenotonsillectomy (AT) is one of the most common pediatric surgeries performed, and is estimated to comprise 530,000 procedures in children under 15 years of age.
- Conditions
- Pediatric Sleep Apnea, Obesity, Morphine Metabolism
- Trial name
- NCT02732795
- Testing
- Morphine pharmacokinetic evaluation
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obstructive Sleep Apnea (OSA)
The Effects of Hypoxic Burden on Executive Function (EF) in Preschool Children With Obstructive Sleep Apnea
The goal of this observational study is to study the effect of hypoxic burden on executive function in preschool children aged 2-6 years who have OSA.
- Trial name
- NCT07023458
- Testing
- Brief-P
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Mahidol University
Obstructive Sleep Apnea
Evaluation of Adherence and Therapeutic Effectiveness of Bi-Flex Versus CPAP in Children With OSA
Context: The obstructive sleep apnea syndrome (OSAS), i.e., snoring with difficulty breathing during sleep, is common in children.
- Trial name
- NCT00458406
- Testing
- Bi-Flex, CPAP
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Philadelphia
Obstructive Sleep Apnea, Balance
Functional Assessment and Sleep Apnea in Obese Children and Adolescents
Childhood obesity increases significantly, and determines several complications in childhood and adulthood, and the worldwide prevalence of childhood obesity has shown a rapid increase in recent decades.
- Conditions
- Obstructive Sleep Apnea, Balance, Obesity, Childhood
- Trial name
- NCT05563311
- Testing
- Exercise on High-intensity interval training
- Where
- Brazil
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Sleep Apnea, Obstructive, Tonsillectomy
The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA).
This is a research study using caffeine in children who have an obstructive sleep apnea (OSA). OSA means children who stop breathing during their sleep due to obstruction in their airway.
- Conditions
- Sleep Apnea, Obstructive, Tonsillectomy, Adenoidectomy, Postoperative Complications
- Trial name
- OSA (NCT00273754)
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- The University of Texas Health Science Center, Houston
Obstructive Sleep Apnea, Down Syndrome
Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)
The overall objective of this randomized clinical trial is to test the effectiveness of a personalized approach to the surgical treatment of OSA in children with Down syndrome (DS).The estimated prevalence of obstructive sleep…
- Trial name
- TOPS-DS (NCT05508971)
- Testing
- DISE-Directed Surgery, Adenotonsillectomy
- Where
- 7 sites in United States
- Volunteers
- 304 people
- Sponsor
- Oregon Health and Science University
Obstructive Sleep Apnea, Pediatric Sleep Apnea
Measurement of Cerebral rSO2 Levels During Sleep in Children With Suspected Obstructive Sleep Apnea
The gold standard of obstructive sleep apnea (OSA) is (PSG)POLYSOMNOGRAPHY. During the examination, the patient is monitored by saturation, EEG and other measurements.
- Trial name
- O2SLEEP (NCT04321083)
- Testing
- INVOS
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obstructive Sleep Disordered Breathing
Characterization of the Tongue in Children With Obstructive Sleep-disordered Breathing
The tongue plays a key role in maintaining upper airway patency during sleep, mainly through the genioglossus, the principal pharyngeal dilator muscle.
- Trial name
- NCT07861230
- Testing
- Cross-sectional assessment
- Where
- Belgium
- Volunteers
- 39 people
- Sponsor
- Université Catholique de Louvain
Obstructive Sleep Apnea
Screening for Obstructive Sleep Apnea Syndrome in Children
To be able to diagnose obstructive sleep apnea syndrome (OSAS) in a patient, polysomnography (PSG) remains the gold standard. However, this is expensive, involves a considerable workload and is quite complex.
- Trial name
- NCT05896176
- Testing
- a clinical examination and anamnesis
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Sleep Apnea
Controlled Trial on Effect of Montelukast Treatment in Children With Obstructive Sleep Apnea Syndrome
Oral therapy with montelukast may lead to improved polysomnographic findings in children with mild to moderate OSAS with and without allergic rhinitis who a priori require T\&A for OSAS.
- Trial name
- NCT00599534
- Testing
- Montelukast
- Where
- 2 sites in United States
- Sponsor
- University of Louisville
Obstructive Sleep Apnea (Mild, Moderate, Severe) as Per Polysomnography
Intranasal Mometasone in Children With Obstructive Sleep Apnea Due to Adenotonsillar Hypertrophy
Obstructive sleep apnea (OSA) in children is a disorder of breathing during sleep characterized by prolonged partial upper airway obstruction and/or intermittent complete obstruction (obstructive apnea) that disrupts normal…
- Trial name
- Nasonex OSA (NCT01671852)
- Testing
- Mometasone furoate nasal spray
- Where
- Canada
- Sponsor
- Children's & Women's Health Centre of British Columbia
Obstructive Sleep Apnea, Nasal Obstruction
Assessment of Adenoidal Obstruction in Children : Clinical Signs Versus Flexible Nasal Endoscopy and Roentgenographic Findings
The term adenoids describes lymphoid tissue on the superior and posterior walls of the nasopharynx, and their hypertrophy is a common condition of childhood.
- Trial name
- NCT01965457
- Where
- Israel
- Volunteers
- 36 people
- Sponsor
- Carmel Medical Center
Difficult Airway, Obstructive Sleep Apnea
Ultrasound to Predict a Pediatric Difficult Airway and Obstructive Sleep Apnea Syndrome in Children
This is a prospective study to see whether ultrasonography can predict difficult airway and/or predict obstructive sleep apnea syndrome (OSAS) in children.
- Trial name
- NCT02227134
- Testing
- Ultrasound
- Where
- United States
- Sponsor
- Vidya Raman
Sleep Apnea, Obstructive, Hypotonia
Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia
Children with hypotonic upper airway obstruction have a high prevalence of severe obstructive sleep apnea, which if not treated has significant clinical consequence.
- Conditions
- Sleep Apnea, Obstructive, Hypotonia, Child, Only
- Trial name
- ssNPA (NCT04846400)
- Testing
- ssNPA
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Michigan