Clinical trials: Sleep Deprivation
Cognitive, Mood and Cognitive Performance
The Acute Effects of Onnit Alpha Brain on Cognition and Mood States
The purpose of this randomized, double-blind, placebo-controlled crossover study is to evaluate the efficacy of the acute effects of an investigational supplement (Alpha Brain or Alpha Brain 2.0) on improving cognitive…
- Conditions
- Cognitive, Mood and Cognitive Performance, Sleep Deprivation, Executive Function (Cognition)
- Trial name
- NCT07495592
- Testing
- Alpha Brain proprietary cognitive dietary supplement, Alpha Brain 2.0 proprietary cognitive dietary supplement
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Stress Disorders, Stress
Measuring the Effectiveness of Forest Therapy to Alleviate Stress Among International Students
International students often face high levels of stress, leading to mental health conditions, from factors including cultural and social change, educational system, financial insecurity and family responsibilities.
- Conditions
- Stress Disorders, Stress, Anxiety, Anxiety Depression (Mild or Not Persistent)
- Trial name
- FTIS-2024 (NCT06792656)
- Testing
- standardized Forest Therapy session (120 min)
- Where
- Australia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- International Nature and Forest Therapy Alliance
Obesity, Diabetes
The Effects of Work Schedule and Sleep Patterns on Caregivers' Health
BACKGROUND. Sleep deficiency (not getting enough sleep) is widespread in American adults and can lead to many harmful health outcomes such as a higher risk of obesity, heart disease, and diabetes.
- Conditions
- Obesity, Diabetes, Cancer, Metabolic Syndrome
- Trial name
- NCT01443156
- Where
- United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sleep Deprivation
The Effects of Sleep Deprivation on Physiological and Perceptual Responses During Exercise
Sleep deprivation has been found to impact exercise performance. The effects of both partial (several hours) and full (24+ hours) sleep deprivation on exercise performance has shown effects on rating of perceived exertion, rate…
- Trial name
- NCT05313932
- Testing
- Sleep deprivation
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Respiratory Disease, Inflammation
Partners in Children's Health (CSN): A Randomized Trial of an Attachment Based Intervention
The goal of this randomized controlled trial is to evaluate the impacts of an attachment-based intervention (Attachment Biobehavioral Catch-Up (ABC) and Home Book-of-the-Week (HBOW) program on emerging health outcomes (i.e.…
- Conditions
- Respiratory Disease, Inflammation, Insufficient Sleep, Digestive Disease
- Trial name
- NCT06002685
- Testing
- Attachment and Biobehavioral Catch-Up, Home-Based Book-of-the-Week
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Mood Disorders, Major Depressive Disorder
Immune Activation, Neural Plasticity and Depression
Major depressive disorder (MDD) is a chronic, recurring and potentially life-threatening illness that affects up to 10% of the population across the globe.Increasing evidence indicates a clear link between immune dysfunction and…
- Conditions
- Mood Disorders, Major Depressive Disorder, Sleep Deprivation
- Trial name
- NCT06306248
- Testing
- Total sleep deprivation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS San Raffaele
Sleep Deprivation
Study of Single Doses of HBS-104 in Acutely Sleep-deprived Healthy Participants
This is a study to evaluate the pharmacodynamic effects, safety, tolerability, and pharmacokinetics of HBS-104 in acutely sleep-deprived healthy adult participants.
- Trial name
- NCT07848659
- Testing
- HBS-104
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Harmony Biosciences Management, Inc.
Sleep, Intensive Care Unit Syndrome
Sleep Bundle for Improving Sleep in ICU Patients
Summary of the project : Lack or disturbances of sleep are major problems in patients staying in intensive care unit (ICU) due to the particular environment.
- Trial name
- NCT03247062
- Testing
- Quality improvement - sleep bundle
- Volunteers
- 130 people
- Sponsor
- University Hospital, Geneva
Sleep Deprivation
Impact of THN102 on Attention, Wakefulness and Cognitive Performance During Total Sleep Deprivation
Study Objectives: THN102 is a new combination between modafinil and flecainide low-dose, a documented glial connexin inhibitor. Efficacy of THN102 was compared to modafinil and to placebo on parameters impaired by total sleep…
- Trial name
- NCT03182413
- Testing
- Modafinil, THN102
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Theranexus
Sleep Deprivation
EEG Analysis for the Objective Assessment of Drowsiness
The objective of this clinical study is to develop solutions for the evaluation and management of drowsiness, based on 2 EEG sensors only, aiming at reducing the risk of accidents related to secondary hypersomnolence (sleepiness…
- Trial name
- MEEGASAFE (NCT05453643)
- Testing
- sleep deprivation patterns
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Physip S.A
Sleep Deprivation, Obesity
Sleep and Metabolism
The goal of this study is to uncover sleep and circadian mechanisms contributing to adverse metabolic health. The protocol is a 21 day (7 outpatient days, 14 inpatient days) mechanistic randomized-crossover study designed to…
- Conditions
- Sleep Deprivation, Obesity, Glucose Intolerance, Weight Gain
- Trial name
- SAM (NCT05775627)
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sleep Deprivation, Sleep
Metabolic and Cognitive Parameters Following Partial Sleep Deprivation
The purpose of this study is to determine whether partial sleep deprivation, as compared with normal sleep, influences certain metabolic and cognitive parameters, related to food intake, hunger and memory functions, when…
- Trial name
- NCT01823263
- Testing
- Portion Size Task, Blood sample, Interference task
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Lifestyle Factors, Overweight and Obesity
Effect of Sleep Extension on Ceramides in People With Overweight and Obesity
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity.
- Conditions
- Lifestyle Factors, Overweight and Obesity, Insulin Sensitivity, Eating Habit
- Trial name
- NCT06180837
- Testing
- Sleep Extension Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sleep Deprivation, Sleep
The Effects of Acute Total Sleep Deprivation Versus Normal Sleep on Metabolism
The study proposes to investigate whether acute total deprivation affects metabolism as measured through blood and peripheral tissues.
- Trial name
- NCT01800253
- Testing
- Inhibitory task, Blood samples, Tissue samples
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Acute Coronary Syndromes (ACS), Sleep Quality
Eye-Ear Sleep Band for Sleep Quality in Coronary Care Unit
Sleep disturbances are common in patients admitted to the coronary care unit (CCU), where continuous light, noise, and monitoring equipment disrupt normal sleep.
- Conditions
- Acute Coronary Syndromes (ACS), Sleep Quality, Sleep Deprivation
- Trial name
- EESQ-CCU (NCT07490743)
- Testing
- Eye-Ear Sleep Band, Standard CCU Care
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Koç University
Post Traumatic Stress Disorder, Sleep Deprivation
Explanation About Sleep in Post Trauma Patients
This study is designed to test the effect of an explanation about the first sleep following trauma exposure, on the development of Post Traumatic Stress Disorder (PTSD) in the months following the traumatic event.
- Trial name
- NCT01684085
- Testing
- Explanation encouraging sleep, Explanation discouraging sleep, Lorazepam
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Poor Quality Sleep, Sleep Deprivation
The Comparison of Dexmedetomidine and Midazolam for the Sleep in Intensive Care Unit
The investigators are going to compare the sleep quality and quantity between dexmedetomidine group and midazolam group using 24 hour polysomnography in critically ill patients.
- Conditions
- Poor Quality Sleep, Sleep Deprivation, Sleep Arousal Disorders, Delirium
- Trial name
- NCT01966315
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Seoul National University Hospital
Sleep Deprivation, Sleep
Sleep Headphones and HDU: a Novel Intervention and Sound Evaluation
It is well established that patients sleep poorly in the Intensive Care Unit (ICU), and excessive noise is considered to be a modifiable cause of this.
- Trial name
- SHH: Noise! (NCT03774212)
- Testing
- Active noise cancelling headphones
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- University of Edinburgh
Cognitive Dysfunction, Sleep Deprivation
Effects of Partial Sleep Deprivation on Cognitive Function of Anesthesiologists
The purpose of this study was to evaluate differences in cognitive functions at baseline and following night shift at a trauma center among faculty anesthesiologists.
- Trial name
- sleep (NCT03784560)
- Testing
- The Psychomotor Vigilance Task (PVT), Epworth Sleepiness Scale, Karolinska sleeping scale
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Prematurity, Parenting
Study of the Quality of Sleep of Parents of Premature Children Compared to Parents of Full-term Children
This study evaluate the incidence of sleep disorders in parents of premature children hospitalized in unit care of neonatalogy or intensive unit care of neonatalogy, compared to parents of full-term child in maternity.
- Conditions
- Prematurity, Parenting, Sleep Deprivation
- Trial name
- SLEEP-PP (NCT03693651)
- Where
- France
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest