Clinical trials: Sleep Deprivation
Chronic Respiratory Failure
Adaptation to Nocturnal Noninvasive Ventilation in Patients With Chronic Respiratory Failure (ROOMILA)
BACKGROUND: Adaptation to noninvasive ventilation (NIV) is a critical step for acceptability and efficacy of this treatment during sleep in patients with chronic respiratory failure.
- Trial name
- ROOMILA (NCT01255111)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Groupe de Recherche sur le Handicap Respiratoire
Sleep Deprivation
Call- Associated Acute Fatigue in Surgical Residency
The study aimed to evaluate the effects of 24-Hour-Call-associated acute partial sleep deprivation on surgical residents' technical and cognitive performance in a virtual reality (VR) setting.
- Trial name
- CAFIS (NCT01284842)
- Testing
- 24-Hour-Call
- Where
- Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Sleep Deprivation
Sleep Promotion in Critically Ill and Injured Patients Cared for in the Intensive Care Unit
Sleep deprivation in healthy volunteers is associated with immune dysfunction. This adverse effect of sleep deprivation likely occurs in patients suffering from acute injury and critical illness requiring intensive care unit…
- Trial name
- NCT01082016
- Testing
- Sleep Enhancement Program (SEP)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Arizona
Gastroesophageal Disease
To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure
The purpose of this study is to determine if sleep deprivation results in increased esophageal acid exposure in healthy controls and gastroesophageal reflux disease (GERD) patients.
- Trial name
- IRUSESOM0428 (NCT01093339)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Southern Arizona VA Health Care System
Sleep Deprivation, Depression
Work Hour Reductions, Medical Errors, and Intern Well-Being at Providence St. Vincent Medical Center Intensive Care Unit
The purpose of this study is to determine whether reducing intern work hours and eliminating extended shifts in the intensive care unit will reduce prescribing errors and improve intern well-being.
- Trial name
- NCT00996320
- Testing
- Reduced work hour schedule
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Providence Health & Services
Healthy
Effects of Sleep Deprivation on Food Intake and Motor Activity in Man
Evidence that shortened period of sleep could be a risk factor for weight gain and obesity has grown over the past decade. Concurrent with the obesity epidemic, numerous studies have reported a parallel epidemic of chronic sleep…
- Trial name
- NCT00986492
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Major Depression
Chronos: the Use of Chronobiological Treatment in Depression
The primary objective of the present study is to examine whether the combination of the antidepressant duloxetine and chronotherapeutic methods (including sleep deprivation, light therapy, and maintaining a regular sleep-wake…
- Trial name
- NCT00149110
- Testing
- Sleep deprivation, Light therapy, Diurnal rhythms
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Hillerod Hospital, Denmark
Aging, Sleep Deprivation
Effects of Chronic Sleep Restriction in Young and Older People
The purpose of this study is to examine the consequences of chronic sleep restriction on nighttime sleep, daytime alertness, performance and memory functions, and metabolic and cardiovascular function, and to determine if the…
- Conditions
- Aging, Sleep Deprivation, Metabolic Syndrome
- Trial name
- NCT00506428
- Testing
- chronic sleep restriction
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Sleep Deprivation
Effect of Work Load and Sleep Deprivation on Medical Staff's Driving Skills
Long and unorthodox working hours (e.g. 24 hours or 23pm-07am shifts for doctors and nurses respectively) combined with sleep deprivation, may affect cognitive functions such as response time and concentration.
- Trial name
- NCT00849706
- Testing
- Study participants will work their regular shifts, and tested after night shifts.No shifts will be added because of the study.
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Sleep Deprivation
Cardiovascular Effects of Partial Sleep Deprivation
Background: Sleep curtailment is common and is associated with increased mortality due to cardiovascular causes. However, the mechanisms are not completely understood.We hypothesized that partial sleep deprivation caused however…
- Trial name
- NCT00669513
- Testing
- Partial sleep deprivation
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sleep Deprivation, Epilepsies, Partial
A Study of Lyrica as Treatment for Sleep Problems in Patients With Sleep Problems and Seizures
The purpose of this study is to determine the effects of pregabalin on sleep problems in patients with seizures.
- Trial name
- NCT00643136
- Testing
- Pregabalin
- Where
- 2 sites in Netherlands
- Volunteers
- 17 people
- Sponsor
- Pfizer
Epilepsy
Activating Effects of Sleep Deprivation on Synchronized MEG-EEG Recordings of Epilepsy Patients With Non-Diagnostic EEG
This study will evaluate how the state of being completely deprived of sleep has an effect on recordings of magnetoencephalography (MEG) and electroencephalography (EEG), in relation to how alert someone is and how sleepy someone…
- Trial name
- NCT00071370
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Obstructive Sleep Apnea, Metabolic Syndrome X
Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress
The purpose of this study is to define the mechanism(s) through which Obstructive Sleep Apnea/Hypopnea (OSAH) promotes abnormal metabolic processes which characterize the metabolic syndrome.
- Trial name
- NCT00177892
- Testing
- sleep disruption, sleep with and without positive pressure
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Insomnia, Sleep Disorder
Single Dose Pharmacokinetic and Pharmacodynamic Evaluation of Three Different Doses of Zolpidem in Children
This is a multicenter trial to evaluate the single-dose safety, tolerability and pharmacokinetics-pharmacodynamics of Zolpidem in a group of children with sleep disturbances stratified by age and dose.
- Trial name
- NCT00494468
- Testing
- Zolpidem
- Where
- 11 sites in United States
- Volunteers
- 63 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Sleep Deprivation
Effects of Sleep Loss on Endothelial Function and Cytokine Levels in Internal Medicine Residents
Work requirements for medical trainees result in substantial sleep loss. Sleep loss has been associated with increased levels of certain inflammatory hormones that could have negative impact on blood vessel function.
- Trial name
- NCT00272233
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yale University
Sleep Deprivation
A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation
The purpose of this study is to determine whether or not a low calorie, low glycemic index diet with omega-3 fatty acid supplements can prevent some of the negative consequences of sleep deprivation.
- Trial name
- NCT00123214
- Testing
- Controlled Dietary Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- St. Vincent's Medical Center