Clinical trials: Sleep Disorder (Disorder)
Health Personnel, Stress
Cereset Research In Healthcare Workers During COVID-19
The purpose of this study is to evaluate the use of Cereset Research to improve the symptoms of stress in healthcare workers in an open label, waitlist controlled pilot clinical trial, during the period of COVID-19.
- Conditions
- Health Personnel, Stress, Anxiety, Insomnia
- Trial name
- NCT04682197
- Testing
- Cereset Research
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sleep Apnea, Obstructive
Evaluating the Relationship Between Sleep-Disordered Breathing and Daytime Alertness
Obstructive sleep apnea (OSA) is a serious sleep disorder in which a person repeatedly stops breathing, or experiences shallow breathing for short periods of time during sleep.
- Trial name
- NCT00393913
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Obstructive Sleep Apnea, Snoring
Childhood Adenotonsillectomy Study for Children With OSAS
The purpose of this research is to determine the effect of adenotonsillectomy surgery (removal of tonsils and adenoids) on obstructive sleep apnea syndrome (OSAS) in children.
- Trial name
- CHAT (NCT00560859)
- Testing
- Adenotonsillectomy (AT) - removal of adenoids and tonsils, Watchful Waiting
- Where
- 6 sites in United States
- Volunteers
- 453 people
- Sponsor
- University of Pennsylvania
HIV, AIDS
Atripla to Stribild Switch Study to Evaluate Sleep Disturbances
Switch patients from Atripla to Stribild will be evaluated to see if patients have less sleep disturbances.
- Conditions
- HIV, AIDS, Sleep Disorders
- Trial name
- NCT02477527
- Testing
- Stribild
- Volunteers
- 21 people
- Sponsor
- Midtown Medical Center, Tampa, FL
Restless Legs Syndrome, Restless Legs Syndrome (RLS)
Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)
This is a multi-center, Phase III study to evaluate the safety and tolerability of proposed dose conversion recommendations for RLS subjects converting from ropinirole immediate release to ropinirole controlled-release for RLS.
- Trial name
- NCT00256854
- Testing
- Ropinirole IR 1 mg, Ropinirole IR 2 mg, Ropinirole CR 2 mg
- Where
- 30 sites in United States
- Volunteers
- 135 people
- Sponsor
- GlaxoSmithKline
Women's Health, Insomnia
A Study of MUSE Device for Midlife Women
The purpose of this study is to see if it is feasible for midlife women to wear a brain activity sensing headband (Muse-S) for management of sleep disturbances such as insomnia and sleep disruption
- Conditions
- Women's Health, Insomnia, Sleep Disturbance
- Trial name
- NCT05972486
- Testing
- Muse-S™ headband system
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Migraine, Headache
RELAXaHEAD for Headache Patients (Phase II)
The goal of this research is to assess the utility of smartphone-based progressive muscle relaxation (PMR) for the treatment of migraine and sleep.
- Conditions
- Migraine, Headache, Multiple Sclerosis, Insomnia
- Trial name
- NCT05466682
- Testing
- Smartphone-Based Progressive Muscle Relaxation Therapy (PMR), Monitored Usual Care (MUC)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- NYU Langone Health
Insomnia, Spinal Cord Injury
Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia
The purpose of this study is to determine if replacing melatonin function with a melatonin agonist (ramelteon) in individuals that lack endogenous melatonin production (tetraplegia) helps to alleviate self-reported sleep…
- Conditions
- Insomnia, Spinal Cord Injury, Tetraplegia, Sleep Disorders
- Trial name
- NCT00507546
- Testing
- Ramelteon
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Central Apnea, Heart Failure
Buspirone as a Potential Treatment for Recurrent Central Apnea
The purpose of this study is to determine whether buspirone compared to acetazolamide and to placebo will reduce the number and/or severity of breathing pauses during sleep that occur in some patients with Heart Failure.
- Trial name
- CSA treatment (NCT00746954)
- Testing
- Acetazolamide, Buspirone
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- VA Office of Research and Development
Insomnia, Fatigue
Cognitive Behavioral Therapy +/- Armodafinil for Insomnia and Fatigue Following Chemotherapy
This is a four-arm, randomized, controlled, clinical trial examining the efficacy of of cognitive behavioral therapy (CBT)-I and armodafinil in reducing insomnia in 226 female breast cancer patients who report sleep disturbances…
- Conditions
- Insomnia, Fatigue, Breast Cancer
- Trial name
- NCT01091974
- Testing
- armodafinil, CBT-I
- Where
- 2 sites in United States
- Volunteers
- 138 people
- Sponsor
- University of Rochester
Posttraumatic Stress Disorders, Chronic Insomnia
Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study)
This study aims to examine whether integrating insomnia and PTSD treatment will enhance sleep, PTSD, and quality of life outcomes.
- Trial name
- NCT02774642
- Testing
- CBTI-PE, Hygiene-PE
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- VA Office of Research and Development
Idiopathic Hypersomnia, Narcolepsy
A Study to Investigate the Effect of XYWAV on Sleepiness, Polysomnography, and Functional Outcomes in Participants With Idiopathic Hypersomnia or Narcolepsy
This study will assess the safety and efficacy of JZP258 (XYWAV) on sleepiness, polysomnography, and functional outcomes in patients with idiopathic hypersomnia (IH) or narcolepsy.
- Trial name
- NCT05875974
- Testing
- JZP258 (XYWAV)
- Where
- 32 sites in United States, Canada
- Volunteers
- 199 people
- Sponsor
- Jazz Pharmaceuticals
Restless Legs Syndrome
A Follow-up Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome
The purpose of this study is to assess the long-term safety, tolerability and the long-term efficacy of rotigotine treatment in adolescents with idiopathic Restless Legs Syndrome (RLS).
- Trial name
- NCT03992196
- Testing
- Rotigotine 1 mg/24 h, Rotigotine 2 mg/24 h, Rotigotine 3 mg/24 h
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- UCB Biopharma SRL
Insomnia, Sleep Disorders
Treating Sleep Problems in VA Adult Day Health Care
The Veterans Millennium Health Care and Benefits Act (Millennium Act) of 1999 mandated the Department of Veterans Affairs (VA) to provide non-institutional long-term care to veterans.
- Trial name
- HERO-ADHC (NCT01259401)
- Testing
- Sleep Intervention Program, Sleep Education control
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- VA Office of Research and Development
Excessive Daytime Sleepiness, Narcolepsy
Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome
The purpose of this study is to assess patient reported outcomes with armodafinil treatment in terms of improvement in sleepiness, satisfaction with treatment, impact on ability to engage in life activities (ie, daily or work and…
- Conditions
- Excessive Daytime Sleepiness, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)
- Trial name
- NCT00228566
- Testing
- Armodafinil
- Where
- 43 sites in United States
- Volunteers
- 247 people
- Sponsor
- Cephalon
Sleep Disordered-breathing
Comparison of 2 Different Hook-up Protocols to Perform Home-based Polysomnography
Comparison of 2 hook-up protocols to perform home-based sleep studies in patients suspected of sleep-disordered breathing. First one: hook-up is performed in the hospital, around 4 PM, and the patient go home with the portable…
- Trial name
- NCT01361854
- Testing
- polysomnography
- Where
- Belgium
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Insomnia, Sleep Deprivation
Study of the Effects of HIRREM-SOP for Insomnia
Prior research studies have shown benefit for use of a technique called High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), to reduce symptoms of moderate to severe insomnia.
- Trial name
- NCT03607994
- Testing
- HIRREM-SOP, NCC
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Insomnia, Depression
A Novel Use of a Sleep Intervention to Target the Emotion Regulation Brain Network to Treat Depression and Anxiety
Several lines of evidence suggest that unhealthy sleep patterns contribute to depressive symptoms through disruption of brain networks that regulate emotional functions.
- Trial name
- NCT04424407
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Stanford University
Primary Fibromyalgia
BEdtime Sublingual TNX-102 SL as Fibromyalgia Intervention Therapy (BESTFIT)
TNX-102 capsules [formerly known as very low dose (VLD) cyclobenzaprine] at bedtime have shown promise as a treatment of fibromyalgia, but the drug required new formulation technology for bedtime use.
- Trial name
- BESTFIT (NCT01903265)
- Testing
- TNX-102 SL 2.8mg
- Where
- 17 sites in United States
- Volunteers
- 205 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Nocturia, Daytime Sleepiness
Cross-over Study of Armodafinil Treatment of Daytime Sleepiness Associated With Treated Nocturia
The objective of the study is to evaluate armodafinil as a wakefulness-promoting therapy as a means of improving residual daytime sleepiness in patients with treated nocturia.
- Trial name
- NCT02151253
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Duke University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.