Clinical trials: Sleep Disorder (Disorder)
Obstructive Sleep Apnea, Pregnancy
Incidence of Obstructive Sleep Apnea in Pregnancy
Obstructive sleep apnea is a condition characterized by obstruction of the upper airways and episodes of apnea and hypopnea during sleep. It is associated with significant adverse health effects.
- Trial name
- OSA (NCT00462306)
- Testing
- Survey: Berlin questionnaire
- Where
- United States
- Volunteers
- 4,577 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Chronic Insomnia
Treating Chronic Insomnia in Breast Cancer Patients
This study is being conducted to evaluate the effectiveness of ramelteon 8mgs in the treatment of insomnia in patients that have completed their first chemotherapy treatment for breast cancer.
- Trial name
- NCT00337272
- Testing
- Ramelteon
- Where
- 10 sites in United States
- Volunteers
- 16 people
- Sponsor
- Accelerated Community Oncology Research Network
Smoking Cessation, Stress
Efficacy and Tolerability of Combination Varenicline With Hydroxyzine as a Potential Smoking Cessation Treatment
This open-label study will evaluate hydroxyzine, a first-generation antihistamine, combined with varenicline, to help smokers abstain from smoking during a 12-week trial period by diminishing the nausea, stress, anxiety, and…
- Conditions
- Smoking Cessation, Stress, Sleep Disturbance, Nausea
- Trial name
- HAVE (NCT04188106)
- Testing
- Varenicline Pill, Hydroxyzine Pill
- Where
- 2 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Insomnia
Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia
The objective of this study is to directly compare 6 sessions of in-person and Internet administered Cognitive-Behavior Therapy for Insomnia (CBTi) to a Minimal Contact control (MC), within an active duty military population to…
- Trial name
- NCT01549899
- Testing
- In-person Cognitive Behavioral Therapy of Insomnia, Internet Cognitive Behavioral Therapy of Insomnia
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Daniel J. Taylor, Ph.D.
Overweight or Obesity
Sleep Extension or Regularity to Reduce Diabetes Risk
The goal of this study is to identify an intervention that improves sleep health and consequently metabolic health by examining whether sleep extension or enforced regularity in short sleepers will have beneficial effects on…
- Trial name
- NCT06128265
- Testing
- Sleep Extension, Sleep Regularity
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Chicago
Narcolepsy
A Study of the Safety and Effectiveness of ADX-N05 in the Treatment of Excessive Daytime Sleepiness
This is a study to evaluate the safety and effectiveness of ADX-N05 compared to placebo in the treatment of excessive daytime sleepiness in adults with narcolepsy.
- Trial name
- NCT01485770
- Testing
- ADX-N05
- Where
- 10 sites in United States
- Volunteers
- 33 people
- Sponsor
- Jazz Pharmaceuticals
Obstructive Sleep Apnea
Comparison of High Flow Nasal Cannula Therapy to Nasal Oxygen as a Treatment for Obstructive Sleep Apnea in Infants
This is a small pilot study that will compare High Flow Nasal Cannula (HFNC) therapy to oxygen nasal cannula therapy on infants who have obstructive sleep apnea (OSA) and are scheduled for a clinically ordered sleep study called…
- Trial name
- NCT02858154
- Testing
- HFNC, Low flow oxygen by nasal cannula
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Insomnia, Posttraumatic Stress Disorder
Suvorexant and Trauma Related Insomnia
Problems sleeping are common after exposure to highly threatening experiences and can occur with and without a diagnosis of posttraumatic stress disorder (PTSD).
- Trial name
- NCT02704754
- Testing
- suvorexant
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Howard University
Obstructive Sleep Apnea
Revised Algorithm for Next Generation DeVilbiss Healthcare AutoAdjust Continuous Positive Airway Pressure (CPAP)
The purpose of this protocol is to improve the current FDA-approved continuous positive pressure auto-titration algorithm, including treatment precision, residual disease detection characteristics and phenotyping with the…
- Trial name
- NCT01797705
- Testing
- DeVilbiss AutoAdjust CPAP with revised algorithm
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- DeVilbiss Healthcare LLC
Obesity
Evaluation of Safety and Health Involvement For Truck Drivers
The current project is a randomized, controlled evaluation of a new weight loss and health promotion intervention for truck drivers.
- Trial name
- SHIFT (NCT02105571)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 452 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Insomnia
Research on Expecting Moms and Sleep Therapy
The overarching goal is to utilize a randomized control design to examine efficacy of web-based cognitive behavior therapy (CBT-I) plus treatment as usual compared to treatment as usual alone for insomnia and depression outcomes…
- Trial name
- REST (NCT02805998)
- Testing
- Web-based CBT-I, Treatment as Usual
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of California, San Francisco
Restless Legs Syndrome
Rotigotine Effect on All-day Functioning and Quality of Life in Subjects With Moderate to Severe Restless Legs Syndrome (RLS)
The purpose of the study is to show that Rotigotine improves Restless Legs Syndrome (RLS) symptoms in subjects with moderate to severe RLS during both day and evening.
- Trial name
- RESTORE (NCT01569464)
- Testing
- Rotigotine
- Where
- 18 sites in United States
- Volunteers
- 150 people
- Sponsor
- UCB Pharma
Obstructive Sleep Apnea Syndrome
Steroids for Pediatric Apnea Research in Kids
This double-blind, randomized controlled trial will evaluate the use of nasal corticosteroids for the treatment of the childhood obstructive sleep apnea syndrome (OSAS).
- Trial name
- SPARK (NCT02180672)
- Testing
- Nasal Fluticasone
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Children's Hospital of Philadelphia
Traumatic Brain Injury, TBI
TWILIGHT Study: Effect of Light Exposure During Acute Rehabilitation on Sleep After TBI
This study proposes to investigate how well Bright White Light Therapy will work in the acute inpatient rehabilitation units for people whom have experienced a traumatic brain injury for the purpose of treating sleep disruption.
- Conditions
- Traumatic Brain Injury, TBI, Sleep
- Trial name
- TWILIGHT (NCT02214212)
- Testing
- Bright White Light (BWL), Red Light (RL)
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Washington
Aging, Sleep Quality
Effects of Multi-component Exercise on Physical Performance and Sleep Quality in Older Adults
This quasi-experimental study evaluated the effects of an 8-week multi-component group exercise program on physical performance and sleep quality among community-dwelling older adults in Taiwan.
- Conditions
- Aging, Sleep Quality, Physical Performance
- Trial name
- NCT07598123
- Testing
- Multi-component Group Exercise Program
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tunghai University
Renal Pelvis Cancer, Restless Legs Syndrome
Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD)
High doses of gabapentin are associated with pancreatic acinar cell tumors in rats, but there has been no post marketing pancreatic carcinogenicity signal with gabapentin as reported by spontaneous reports in the Adverse Events…
- Conditions
- Renal Pelvis Cancer, Restless Legs Syndrome, Epilepsy, Neuropathic Pain
- Trial name
- NCT01138124
- Testing
- Gabapentin prescriptions
- Volunteers
- 54,202 people
- Sponsor
- GlaxoSmithKline
Insomnia, Insomnia Chronic
Partial Reinforcement II: Three Approaches to Maintenance Therapy for Chronic Insomnia
The study is a three phase sequential study of the medical treatment of insomnia with zolpidem. All participating subjects will receive one month of standard nightly treatment.
- Trial name
- R01 (NCT03774810)
- Testing
- Zolpidem tartrate
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- University of Pennsylvania
Insomnia, Chronic Pain
A Cognitive-Behaviour Therapy (CBT) Self-Management Approach for Insomnia in Chronic Pain: A Randomized Control Trial
This study will test the impact of a cognitive-behavioural self-management approach for the management of insomnia among patients with chronic pain.
- Trial name
- NCT01188460
- Testing
- Self-help manual for insomnia, Sleep diary
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
CSF Circulation
Influence of Yogic Breathwork on CSF Circulation
The purpose of this research study is to determine the influence of yoga breathing practices on cerebrospinal fluid (CSF) circulation, and to find out primarily if a regular practice of 8-week yoga breathing would enhance CSF…
- Trial name
- CSF (NCT03858309)
- Testing
- Breathing Group 1, Breathing Group 2
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sleep-disordered Breathing, Snoring
Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome
Upper airway obstruction (UAO) is an unrecognized source of hemodynamic stress that may contribute to aortic adverse events in persons with Marfan Syndrome (MFS).
- Trial name
- MSB (NCT03985657)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
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