Clinical trials: Sleep Disordered Breathing
Elective Coronary Artery Bypass Grafting (CABG) Surgery, Coronary Artery Disease
Sleep-disordered Breathing and Perioperative Atrial Fibrillation in Cardiac Surgery
In patients undergoing elective coronary artery bypass grafting (CABG) surgery, coronary artery disease, sleep-disordered breathing (SDB), atrial fibrillation (AF) perioperative atrial fibrillation and complications will be…
- Conditions
- Elective Coronary Artery Bypass Grafting (CABG) Surgery, Coronary Artery Disease, Sleep-disordered Breathing (SDB), Atrial Fibrillation
- Trial name
- CONSIDER-AF (NCT02877745)
- Testing
- Stratification, no intervention
- Where
- Germany
- Volunteers
- 1,200 people
- Sponsor
- Michael Arzt
Sleep Disordered Breathing, Apnea of Prematurity
The PARS Study: Paediatric Advanced Respiratory Service Study - An Observational Diagnostic Feasibility Study
Diagnostic investigations in paediatric respiratory and sleep medicine are often challenging due to patient size (due to prematurity), tolerability, and compliance with "gold standard equipment".
- Conditions
- Sleep Disordered Breathing, Apnea of Prematurity, Respiratory Rate, Sudden Unexpected Death in Epilepsy
- Trial name
- PARS (NCT06292299)
- Testing
- Pneumowave
- Where
- 2 sites in United Kingdom
- Volunteers
- 225 people
- Sponsor
- NHS Greater Clyde and Glasgow
Pregnancy Complicated by Cardiovascular Disorders as Postpartum Condition, Delivered During Previous Episode, Breathing-Related Sleep Disorder
nuMoM2b Heart Health Study
This study is looking at the relationship between experiences during pregnancy and cardiovascular health 2 to 3½ years later. The investigators are recruiting women from the approximately 10,000 women who were enrolled and…
- Trial name
- nuMoM2b-HHS (NCT02231398)
- Where
- 15 sites in United States
- Volunteers
- 4,509 people
- Sponsor
- RTI International
Sleep-disordered Breathing, Obstructive Sleep Apnea
Comparison of Sleep Study Results After Partial Intracapsular Tonsillectomy Versus Total Tonsillectomy
The purpose of this study is to demonstrate similar improvements in sleep-disordered breathing as determined by sleep study with microdebrider-assisted partial intracapsular tonsillectomy and adenoidectomy versus total Bovie…
- Trial name
- NCT00887471
- Testing
- PITA or T&A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- State University of New York - Downstate Medical Center
Autonomic Dysfunction
Autonomic Regulation in Prader-Willi Syndrome
To evaluate autonomic regulation in patients with Prader-Willi syndrome with sleep-disordered breathing.
- Trial name
- NCT04118816
- Testing
- Polysomnography, Multiple sleep latency test, Continuous positive airway pressure
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Hypertension, Obstructive Sleep Apnea
Impact of Sleep-Disordered Breathing Management in Systemic Hypertension Control: METASLEEP Project
Hypertension is a frequent condition affecting 11M Spanish citizens and is the leading modifiable contributor to cardiovascular disease and death.
- Trial name
- NCT05986487
- Testing
- CPAP or usual practice, Monitoring and intervention in follow-up
- Where
- Spain
- Volunteers
- 1,523 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Snoring, OSA - Obstructive Sleep Apnea
Serene Sleep Palatal Implant System Clinical Confirmatory Trial in Participants Who Snore or Are Diagnosed With Mild-to-moderate Obstructive Sleep Apnea (OSA).
This clinical investigation is a prospective, non-randomized, parallel-group clinical investigation conducted at two (2) investigative sites.
- Trial name
- NCT07613281
- Testing
- Palatal Implant System
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Serene Sleep, Inc.
Obstructive Sleep Apnea, Obesity
Obesity and Obstructive Sleep Apnea (OSA) in Children
The goal of this research is to study the prevalence of sleep disordered breathing and associated morbidity in obese children and to examine the role of diet and physical activity in the treatment of sleep-disordered breathing in…
- Trial name
- NCT01135147
- Testing
- Diet, Surgery
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Lung Cancer
Early Diagnosis and Treatment of Sleep Disordered Breathing in Lung Cancer
Sleep-disordered breathing at night is a common medical problem. It leads to daytime fatigue, impairment in concentration and daily activities, and a higher risk of cardiovascular disease and life-threatening events.
- Trial name
- NCT03443908
- Testing
- CPAP
- Where
- United States
- Sponsor
- Mark M. Fuster, MD
Sleep Apnea
AirSense 10 AHI Validation Study
The AirSense 10 platform is able to detect respiratory events at night and report these data via telemonitoring. The accuracy of the AirSense 10 will be compared with scoring with polysomnography (PSG).
- Trial name
- NCT03043703
- Testing
- AirSense 10 AutoSet for Her
- Where
- 2 sites in Germany
- Sponsor
- ResMed
Parkinson's Disease, Sleep Disordered Breathing
Sleep Disordered Breathing and Its Impact on Neuro-cognitive Performance and Quality of Life in Parkinson Disease
The purpose of this study is to determine the impact of sleep and breathing problems during sleep on memory, attention, and general well being (quality of life) in people with Parkinson Disease.
- Conditions
- Parkinson's Disease, Sleep Disordered Breathing, Sleep Obstructive Apnea
- Trial name
- NCT02034357
- Testing
- Neurocognitive function, Sleep evaluations
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Miami
Critically Ill, Obstructive Sleep Apnea
Predictors of Upper Airway Function and Sleep-disordered Breathing in the Critically Ill
This is part 2 of the #NCT01618240 under the same IRB protocol #2010P001919. The primary objective of this study is to examine factors that are related to sleep-disordered breathing and upper airway patency in critically ill…
- Trial name
- NCT02112604
- Testing
- Ventilator, Alice PDx, Pulmonary function test
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Sleep Disordered Breathing, Obstructive Sleep Apnea
The Impact of Interscalene Block on Sleep Disordered Breathing
This is a randomized controlled trial evaluating the impact of interscalene block on worsening of upper airway collapse in sleep disordered breathing for patients undergoing ambulatory shoulder surgery.
- Trial name
- OSA-ISB (NCT03718858)
- Testing
- Interscalene Block, Superior Trunk Nerve Block
- Where
- 2 sites in Canada
- Volunteers
- 76 people
- Sponsor
- Women's College Hospital
Sleep-Disordered Breathing, Pulmonary Arterial Hypertension
Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment
Evaluation of the effect of CPAP (continuous positive airway pressure ) treatment in PAH (pulmonary arterial hypertension) and CTEPH (chronic thromboembolic pulmonary hypertension) patients suffering from sleep disordered…
- Conditions
- Sleep-Disordered Breathing, Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
- Trial name
- NCT02583906
- Testing
- CPAP
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sleep Disordered Breathing (SDB), Sleep Apnea
Detection of Sleep Stages and Arousals Using Neural Network Classifiers
The objective of this clinical study is to evaluate the accuracy of the Smart Mask V1 System (herein 'Smart Mask') in measuring sleep stages-Stage N1/N2, Stage N3, Rapid Eye Movement (herein 'REM'), and WAKE-arousals, and the…
- Trial name
- SSAM (NCT07136272)
- Testing
- SSAM, Polysomnography, EnsoSleep
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pathway Medtech, LLC.
Obstructive Sleep Apnea, Sleep Disordered Breathing
Nasal High Flow Therapy in Surgical Patients with Unrecognized Obstructive Sleep Apnea
In this study the investigators will determine whether using high flow oxygen in moderate-to-severe Obstructive Sleep Apnea patients following a major non cardiac surgery is more efficacious than usual care in preventing decrease…
- Trial name
- POSAII (NCT03964376)
- Testing
- Nasal High Flow, Usual Care
- Where
- 8 sites in Canada, Hong Kong and 2 more
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Apnea Syndrome, Apnea, Obstructive
Effect of Hypnosis on Adherence to Continuous Positive Airway Pressure.
The prevalence of sleep-disordered breathing is high, with an apnea-hypopnea index of over 15 per hour found in 49.7% of men and 23.4% of women in the general population (1).
- Trial name
- HypnOSA (NCT06397365)
- Testing
- medical hypnosis
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Solelhac Geoffroy
Sleep Apnea, Sleep Disordered Breathing
Multinight CPAP for Sleep Apnea Patients
Obstructive sleep apnea (OSA) is a prevalent disorders characterized by intermittent obstructions of the upper airway during sleep.
- Trial name
- NCT02635100
- Testing
- CPAP machine with MNT algorithm
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Sleep Disordered Breathing, Obstructive Sleep Apnea
Adenotonsillectomy for Obstructive Sleep-Disordered Breathing in Childhood:The Chania Community Oximetry-Based Study
Obstructive sleep-disordered breathing (SDB) in childhood is a disorder of breathing during sleep characterized by intermittent upper airway obstruction.
- Conditions
- Sleep Disordered Breathing, Obstructive Sleep Apnea, Snoring, Obstructive Sleep Disordered Breathing
- Trial name
- NCT01918007
- Testing
- Adenotonsillectomy (AT)
- Where
- 2 sites in Greece
- Volunteers
- 186 people
- Sponsor
- Chania General Hospital "St. George"
Duchenne Muscular Dystrophy (DMD), Respiratory Function Decline
Respiratory Progression in Adults With Duchenne Muscular Dystrophy.
This is a multicenter, longitudinal observational study aimed at characterizing the natural history of respiratory progression in adults with genetically confirmed Duchenne muscular dystrophy (DMD).
- Conditions
- Duchenne Muscular Dystrophy (DMD), Respiratory Function Decline, Restrictive Lung Disease, Respiratory Failure
- Trial name
- GUP24005 (NCT07879989)
- Where
- 13 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Giannina Gaslini