Clinical trials: Sleep Disorders, Intrinsic
Sleep Disordered Breathing, Sleep Hypopnea
Apnea Hypopnea Index Severity Versus Head Position During Sleep
This study evaluates the correlation of the position of the head during sleep, independent of the position of the torso, and the severity of apnea hypopneas in obstructive sleep apnea.
- Conditions
- Sleep Disordered Breathing, Sleep Hypopnea, Sleep Apnea, Sleep Apnea, Obstructive
- Trial name
- NCT04086407
- Testing
- Dual-axis inclinometer attached to the subject's forehead with tape
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sleep Systems
Stress, Psychological, Sleep Initiation and Maintenance Disorders
Who Benefits More? Optimising Mindfulness Based Interventions for Improved Psychological Outcomes
Mindfulness training has been gaining popularity in the past decade as a means of improving general well-being. This trend appears in response to the new stressors that have arisen with the increased stress of the 21st century.
- Trial name
- NCT04417153
- Testing
- Mindfulness Based Intervention
- Where
- Singapore
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Hemodialysis
Erciyes University Faculty of Health Sciences
Sleep disorders are important to place among the symptoms frequently seen in hemodialysis patients. Among sleep disorders, restless legs syndrome is the most common.
- Trial name
- NCT06156930
- Testing
- Intervention group lavender oil
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Congestive Heart Failure, Sleep Apnea Syndromes
Reducing Heart Failure Re-admissions by Enhancing Sleep Apnea Treatment Adherence
Sleep apnea, characterized by abnormal breathing at night, is often untreated in patients with heart failure. Helping patients to effectively use the most common form of treatment for sleep apnea, positive airway pressure…
- Trial name
- NCT02312765
- Testing
- AirCare App
- Volunteers
- 146 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea
Metabolomics of Obstructive Sleep Apnea
This is an R01 funded project that focuses on the utility of metabolomics as a biomarker for OSA. Aims 1 and 3 leverages banked samples previously collected from subjects with and without OSA at the University of Pennsylvania and…
- Trial name
- MOSA (NCT04572269)
- Testing
- No Intervention
- Where
- 2 sites in United States, Iceland
- Volunteers
- 388 people
- Sponsor
- University of Pennsylvania
Sleep Apnea, Sudden Cardiac Death
European Sleep Apnea and Sudden CArdiac Death ProjEct
The objective of ESCAPE-SCD Study is assessment of the effect of sleep apnea on sudden cardiac death risk and cardiovascular outcomes in patients with ischemic cardiomyopathy.
- Conditions
- Sleep Apnea, Sudden Cardiac Death, Heart Failure, Ischemic Cardiomyopathy
- Trial name
- ESCAPE-SCD (NCT02506166)
- Testing
- Positive Airway Pressure Therapy
- Volunteers
- 900 people
- Sponsor
- University Hospital Olomouc
Hypersomnia, Idiopathic
Idiopathic Hypersomnia
Idiopathic hypersomnia (IH) is characterized by non-restoring night-time sleep, excessive daytime sleepiness, sleep inertia, impaired cognitive functioning and autonomic symptoms.
- Trial name
- IDAHO (NCT05150977)
- Testing
- Polysomnography
- Where
- Sweden
- Volunteers
- 69 people
- Sponsor
- Uppsala University
Obstructive Sleep Apnea (OSA), Sleep Apnea - Obstructive
Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea (OASIS)
The objective of this study is to evaluate the safety and effectiveness of the Cryosa System when used as intended to perform the Cryosa Procedure.
- Conditions
- Obstructive Sleep Apnea (OSA), Sleep Apnea - Obstructive, OSA
- Trial name
- (OASIS) (NCT07720219)
- Testing
- Cryosa Procedure
- Volunteers
- 130 people
- Sponsor
- Cryosa, Inc.
Sleep Apnea, Obstructive, Stroke
Stroke and CPAP Outcome Study 2
Obstructive sleep apnea (OSA) is associated with impaired stroke recovery. Treatment with continuous positive airway pressure (CPAP) may prevent this but is limited by poor adherence.
- Conditions
- Sleep Apnea, Obstructive, Stroke, Patient Adherence
- Trial name
- SCOUTS2 (NCT02809430)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Washington
Substance Withdrawal Syndrome
The Effect of Melatonin Upon Post-Acute Withdrawal Among Males in a Residential Treatment Program
Individuals recovering from drug and/or alcohol addiction initially experience the symptoms of acute withdrawal before experiencing the symptoms of post-acute withdrawal (PAWS).
- Trial name
- M-PAWS (NCT02431728)
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Duquesne University
COPD Asthma
The Effect of Progressive Relaxation and Breathing Exercise on Sleep Quality and Exercise Self-Efficacy in Patients With COPD
Aim: This study was conducted to determine the effect of progressive muscle relaxation and breathing exercise on sleep quality and exercise self-efficacy in chronic obstructive pulmonary patients.
- Trial name
- NCT05397275
- Testing
- progressive muscle relaxation+breathe exercises, breathe exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Osmaniye Korkut Ata University
OSA - Obstructive Sleep Apnea
Characterizing Bilateral Hypoglossal Nerve Stimulation During Drug-Induced Sleep Endoscopy
The study will investigate the treatment effect of bilateral genioglossus muscle stimulation on upper airway collapsibility during drug-induced sleep endoscopy in patients implanted with the Inspire hypoglossal nerve stimulator.
- Trial name
- BLISS (NCT06661629)
- Testing
- Nerve stimulation
- Sponsor
- University of Pennsylvania
Postpoliomyelitis Syndrome
Modafinil to Treat Fatigue in Post-Polio Syndrome
This study, conducted at the Walter Reed Army Medical Center, the National Rehabilitation Hospital, and the National Institutes of Health, will examine whether the drug Modafinil can decrease fatigue in patients with post-polio…
- Trial name
- NCT00067496
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sleep Disturbance
Feasibility Study of Personalized Trials to Improve Sleep Quality
The purpose of this pilot study is to assess the feasibility of using N-of-1 methods in a virtual research study of melatonin intervention for poor sleep quality.
- Trial name
- NCT05349188
- Testing
- Melatonin 3 mg, Melatonin 0.5 mg
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Telenursing
Telephone Counseling in the Education of the Patient With Gastritis
It is planned to investigate the effect of telephone counseling on pain and sleep quality in patients with gastritis who have received gastritis management training.
- Trial name
- NCT04669275
- Testing
- Telephone Counselıng
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Eskisehir Osmangazi University
Obesity Hypoventilation Syndrome
Prevalence Rate, and Clinical Characteristics of Obesity Hypoventilation Syndrome Via Screening Patients Admitted to Medical Intensive Care Units
A prospective observation study to screen adult obese (BMI ≥30 kg/m2) patients who were newly admitted to the medical intensive care units and turned out to be diagnosed as Obesity hypoventilation syndrome(OHS).
- Trial name
- NCT02934581
- Where
- Taiwan
- Volunteers
- 52 people
- Sponsor
- National Taiwan University Hospital
Obesity, Sleep Disordered Breathing
Postpartum Weight Loss and Sleep Amongst Obese Women
This study will be a randomized controlled trial involving obese women obtaining prenatal care at an obstetric care clinic. Study subjects will undergo prenatal care in a group setting or prenatal care with a behavioral…
- Conditions
- Obesity, Sleep Disordered Breathing, Weight Loss, Postpartum
- Trial name
- NCT01968330
- Testing
- Go!®to sleep
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of South Florida
Insomnia
Electrophysiologic Changes in Blacks Treated With CBT for Insomnia
Insomnia is a highly prevalent, often debilitating, and economically burdensome condition. Reviews of the literature indicate that there are ethnic differences in sleep behavior, with African Americans objectively and…
- Trial name
- NCT02741336
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Self-Monitoring
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- State University of New York - Downstate Medical Center
Insomnia
the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of HEC83518 Tablets
Multiple Dose Safety, Tolerability, PK ，PD and Food Effect Study of HEC83518 in Healthy Subjects
- Trial name
- NCT04667429
- Testing
- Food, HEC83518
- Where
- China
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
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