Clinical trials: Sleep Disorders, Intrinsic
Obesity, Morbid, Postoperative Pain
Study of the Effect of the Drug Gabapentin on Postoperative Pain and Incidence of Postoperative Nausea and Vomiting
The purpose of this research study is to evaluate the drug gabapentin (Neurontin®) for its ability to reduce postoperative pain, the need for morphine-like pain medication, and the severity and frequency of postoperative nausea…
- Conditions
- Obesity, Morbid, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT00886236
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Medical University of South Carolina
Insomnia
Investigation of the Safety and Efficacy of Long Term Administration of Eszopiclone in Insomnia Patients
To investigate the safety and efficacy of administration of eszopiclone for 6 months in insomnia participants.
- Trial name
- NCT02455271
- Testing
- Eszopiclone
- Where
- 2 sites in Japan
- Volunteers
- 438 people
- Sponsor
- Eisai Co., Ltd.
Sarcoidosis, Sleep Apnea, Obstructive
Prevalence of Obstructive Sleep Apnea Syndrome in Sarcoidosis and Impact of CPAP Treatment on Associated Fatigue Status
Sarcoidosis is a multisystemic granulomatous disease that affects individuals worldwide without known pathogenesis, and the role of comorbidities has not been fully assessed in the scientific literature.
- Conditions
- Sarcoidosis, Sleep Apnea, Obstructive, Fatigue
- Trial name
- SARCOIDOSAS (NCT03926832)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sleep Initiation and Maintenance Disorders
A Study of FK199B to Compare Efficacy With Zolpidem by Polysomnography in Patients With Insomnia
This study is to investigate the efficacy and safety of FK199B (Zolpidem MR Tablet) by polysomnography in patients with insomnia, excluding patients with schizophrenia or manic-depressive psychosis.
- Trial name
- NCT00999219
- Testing
- FK199B, Zolpidem
- Where
- 7 sites in Japan
- Volunteers
- 55 people
- Sponsor
- Astellas Pharma Inc
Sleep Quality , Physical Fitness and Body Mass Index
Correlation Between Sleep Quality , Physical Fitness and Body Mass Index
It is estimated that 10-13% of adults suffer from chronic insomnia. Short sleep duration is linked to obesity, type 2 diabetes, high blood pressure, and cardiovascular diseases.
- Trial name
- NCT06815900
- Testing
- one group .observational study
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Cairo University
Apnea, Obstructive, Tonsillitis
Evaluation of the Functional Impact of Adenotonsilectomy
Spirometric assessment of respiratory function before and after adenotonsillectomy surgery
- Conditions
- Apnea, Obstructive, Tonsillitis, Tonsillar Hypertrophy, Respiratory Function Impaired
- Trial name
- NCT05532228
- Testing
- Adenotonsillectomy
- Where
- Portugal
- Volunteers
- 78 people
- Sponsor
- Instituto de Ciências Biomédicas Abel Salazar
Musculoskeletal Pain, Insomnia
Insomnia in Patients Participating in Interdisciplinary Pain Rehabilitation
The main purpose of this project is to conduct a prospective cohort study in order to better understand the importance of insomnia symptoms in patients referred to interdisciplinary rehabilitation due to chronic pain.
- Trial name
- NCT06478628
- Testing
- Inpatient rehabilitation, Outpatient day rehabilitation
- Where
- Norway
- Volunteers
- 1,500 people
- Sponsor
- Norwegian University of Science and Technology
Nasal Obstruction, Nasopharyngeal Obstruction
Administration of Dexamethasone in PONV Prophylaxis in Children Undergoing Adenotomy
Adenotomy, together with tonsillectomy, belongs among the most frequently performed surgical procedures in paediatric patients. These surgical procedures are associated with the second highest incidence of post-operative nausea…
- Conditions
- Nasal Obstruction, Nasopharyngeal Obstruction, Snoring, Apnea, Obstructive
- Trial name
- NCT03398044
- Testing
- Dexamethasone
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Ostrava
Insomnia
A Long-Term Safety and Efficacy Study of Eszopiclone in Elderly With Primary Chronic Insomnia
To evaluate the long-term safety and efficacy of eszopiclone administered for 12 weeks in elderly subjects with primary chronic insomnia.Administration of eszopiclone 2 mg daily at bedtime for 12 weeks in elderly subjects with a…
- Trial name
- NCT00386334
- Testing
- Eszopiclone
- Where
- 82 sites in United States
- Volunteers
- 388 people
- Sponsor
- Sumitomo Pharma America, Inc.
Preterm Labor, Anxiety
Bryophyllum Pinnatum Treatment of Anxiety Related to Signs of Preterm Birth
The present IIT (Investigator-Initiated Trial) study is a prospective, randomised, placebo-controlled, double blind trial. Women hospitalised with signs of preterm birth can be recruited for the study.
- Trial name
- NCT05110599
- Testing
- Bryophyllum 50% chewable tablets
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Christian Haslinger
Sleep Apnea, Obstructive, Endothelial Dysfunction
Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal
Obstructive sleep apnea hypopnea syndrome (OSAS) is a frequent disease with neuropsychological and cardiovascular (CV) consequences.
- Trial name
- ORTAP (NCT05939934)
- Testing
- Mandibular advancement device treatment
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Angers
Sleep Apnea, Obstructive, Stroke
Stroke and CPAP Outcome Study 2
Obstructive sleep apnea (OSA) is associated with impaired stroke recovery. Treatment with continuous positive airway pressure (CPAP) may prevent this but is limited by poor adherence.
- Conditions
- Sleep Apnea, Obstructive, Stroke, Patient Adherence
- Trial name
- SCOUTS2 (NCT02809430)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Washington
Insomnia, Sleep
Blue Blockers at Night and Insomnia Symptoms
Under entrained conditions, humans maintain a consolidated nocturnal sleep episode that coincides with environmental darkness and endogenous melatonin secretion.
- Trial name
- NCT02698800
- Testing
- Blue blocking (BB) lenses, Clear lenses
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obstructive Sleep Apnea
Delphi Consensus Excessive Daytime Sleepiness in OSA
The objective of this study is to generate expert consensus statements on the differential diagnosis, definition, and management of EDS in patients with OSA who are adequately treated with primary therapy.
- Trial name
- NCT05055271
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King's College London
Obstructive Sleep Apnea
Cardiopulmonary Exercise Test in Patient With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) can be described as a condition characterized by repetitive obstruction of the upper airway resulting in oxygen desaturation and awakening from sleep, loud snoring, and increased daytime sleepiness .
- Trial name
- NCT03300700
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Sleep Apnea, Heart Failure
Cardiac Function After CPAP Therapy in Patients With Chronic Heart Failure and Sleep Apnea. A Multicenter Study
The role of continuous positive airway pressure (CPAP) in cardiac function in patients with CSA and OSA has been studied with varying results.
- Conditions
- Sleep Apnea, Heart Failure, Cardiovascular Diseases
- Trial name
- NCT00404807
- Testing
- CPAP(Continuous Positive Airway Pressure)
- Where
- Spain
- Volunteers
- 245 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Obstructive Sleep Apnea
Efficacy of Stellate Ganglion Block in Obstructive Sleep Apnea
The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are: Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were…
- Trial name
- OSA (NCT06265792)
- Testing
- routine rehabilitation treatment, Stellate ganglion block
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Zeng Changhao
Obstructive Sleep Apnea Syndrome, Glaucoma
Obstructive Sleep Apnea Syndrome in Glaucoma
The aim of the study is to determine if plasma matrix-metalloproteinase activity can predict glaucoma in patients with OSAS and if the level of plasma matrix-metalloproteinase activity will decrease after one month of…
- Trial name
- NCT00313092
- Testing
- nCPAP treatment
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Selim Orguel
Insomnia, Anesthesia
Orexin-A Levels in Insomnia Patients
In the pathophysiology of insomnia, the increase of the orexin-A (OXA) peptide released from orexin neurons in the lateral hypothalamus plays an important role. Orexins takes part at the emergence of anesthesia.
- Trial name
- NCT05664295
- Testing
- Jenkins Sleep Disorders scale and Epworth Sleepiness scale
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Restless Legs Syndrome (RLS), End-Stage Renal Disease
Effect of Intra-Dialytic Muscle Energy Technique on Restless Leg Syndrome in Hemodialysis Patients
The goal of this clinical trial is to learn if intra-dialytic Muscle Energy Technique (MET) can reduce symptoms of restless legs syndrome (RLS) in people with end-stage renal disease (ESRD) receiving maintenance hemodialysis.
- Trial name
- MET-RLS (NCT07748065)
- Testing
- Muscle Energy Technique, Routine Medical Treatment and Hemodialysis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
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