Clinical trials: Sleep Disorders, Intrinsic
Sleep Apnea
Artificial Neural Network Directed Therapy of Severe Obstructive Sleep Apnea
The investigators have developed a simple, accurate, and a point-of-care, computer-based clinical decision support system (CDSS) not only to detect the presence of sleep apnea but also to predict its severity.
- Trial name
- NCT01286636
- Testing
- computer model, Polysomnogram
- Where
- United States
- Sponsor
- State University of New York at Buffalo
Rotator Cuff Syndrome, Rotator Cuff Injury
Effect Of Sleeping Posture Guidance On Sleep Quality In Patients With Rotator Cuff Syndrome
This study investigates sleep quality in patients with Rotator Cuff Syndrome (RCS) undergoing physical therapy treatment. Existing literature presents a gap regarding longitudinal studies evaluating the impact of physical therapy…
- Conditions
- Rotator Cuff Syndrome, Rotator Cuff Injury, Sleep Disorder (Disorder)
- Trial name
- NCT07376811
- Testing
- Physical Therapy, Physical Therapy + Sleep Guidance
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Federal University of São Paulo
Effect of Kefir on Healthy Adults
Effects of Kefir Consumption on Health Outcomes: Gastrointestinal System, Immunity, Biochemical Parameters, Body Composition, Sleep Quality and Mental Well Being in Healthy Adults
The goal of this clinical trial is to evaluate the effects of the administration of kefir on gastrointestinal system, mental health, biochemical parameters, immunity and inflammation processes as well as the sleep quality…
- Trial name
- KefirCons (NCT06612164)
- Testing
- kefir
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Medipol University
Sleep Disordered Breathing, Able Bodied
Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment
Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive…
- Trial name
- CSA (NCT04118387)
- Testing
- Acetazolamide + supplemental oxygen + PAP therapy, Zolpidem + PAP therapy, Buspirone + PAP therapy
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Insomnia Disorder
Safety and Efficacy Study of YZJ-1139 Tablets in Insomnia Disorder
The main purpose of this study is to assess efficacy of YZJ-1139 for 28 days in adult subjects with insomnia disorder. Efficacy will be evaluated on objective and subjective sleep parameters.
- Trial name
- NCT06975514
- Testing
- YZJ-1139, Zolpidem
- Where
- 16 sites in China
- Volunteers
- 61 people
- Sponsor
- Shanghai Haiyan Pharmaceutical Technology Co., Ltd.
Insomnia
A Multicenter Observational Study of Daridorexant in the Treatment of Insomnia
This study aims to evaluate the effectiveness and safety of daridorexant, a novel dual orexin receptor antagonist (DORA), in patients with insomnia.
- Trial name
- NCT07847021
- Testing
- Daridorexant 50 mg
- Where
- 25 sites in China
- Volunteers
- 500 people
- Sponsor
- Shanghai Mental Health Center
POST-Covid 19, Anxiety
Effects of Cranial Electrotherapy Stimulation on Anxiety of Patients After COVID-19
The aim of the study is to investigate the effect of cranial electrotherapy stimulation (CES), for one hour a day over 3 weeks pulmonary rehabilitation (PR) program on symptoms of anxiety in post-Covid patients.
- Trial name
- NCT05126511
- Testing
- Application of CES via ear clips
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Schön Klinik Berchtesgadener Land
Obstructive Sleep Apnea
Study of AD128 Versus Placebo in Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) is the most common and serious of the sleep disorders. Long-term, OSA is associated with increased morbidity and mortality, with a number of adverse cardiovascular, neurocognitive, metabolic, and…
- Trial name
- NCT04449133
- Testing
- AD128
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Istituto Auxologico Italiano
Insomnia
Evaluation of Spa Treatment on Insomnia
Persistant insomnia is a common sleep disorder that affects approximately 20% of the French population. The standard treatment for chronic insomnia is Cognitive-Behavioral Therapy (CBT).
- Trial name
- SOMNOTHERM (NCT03991247)
- Testing
- Computerized behavioral therapy program delivered by internet for insomnia management, Spa treatment
- Where
- France
- Volunteers
- 178 people
- Sponsor
- Association Francaise pour la Recherche Thermale
Mood and Sleep Quality
A Study to Evaluate the Efficacy of VL-NL-02 on Sleep Quality.
The goal of this clinical trial is to study the impact of VL-NL-02 in improving sleep quality, restorative sleep complaints, quality of life, stress levels, and sleep stages.
- Trial name
- NCT06056258
- Testing
- VL-NL-02
- Where
- 5 sites in India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Primary Dysmenorrhea
Yoga Effects in Primary Dysmenorrhea
The goal of this clinical trial was to assess whether a yoga-based exercise program could improve aerobic endurance, sleep quality, and reduce menstrual symptoms and pain in young women aged 18-25 with primary dysmenorrhea.
- Trial name
- NCT07020338
- Testing
- Yoga Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Obstructive Sleep Apnea
Can Postoperative Outcomes be Predicted From Asking OSA Screening Questions Pre-operatively?
The proposed research will determine whether a 6-item screening questionnaire previously shown to correlate with moderate or severe OSA is useful for predicting postoperative outcomes in children undergoing surgery under general…
- Trial name
- NCT02930538
- Testing
- Survey
- Where
- United States
- Sponsor
- Nationwide Children's Hospital
Sleep, Sleep Apnea
Research Framework Exploring Sleep Health
This is a digital health study in which participants are recruited to collect sleep and activity data from digital activity trackers.
- Conditions
- Sleep, Sleep Apnea, Obesity, Mood
- Trial name
- REFRESH (NCT05197738)
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Obstructive Sleep Apnea
A Pilot Study of Biomarkers in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is common and is a risk factor for postoperative complications, including respiratory and cardiac events and delirium.
- Trial name
- Cytokine OSA (NCT02325687)
- Testing
- Lumbar Puncture (Standard-of-Care)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hospital for Special Surgery, New York
Insomnia, Sleep Initiation and Maintenance Disorders
Efficacy and Safety Study of Org 50081 (Esmirtazapine) in Elderly Participants (P05709)
This study was conducted to investigate the efficacy of treatment with Org 50081 (Esmirtazapine) compared to placebo in elderly participants with chronic primary insomnia.
- Conditions
- Insomnia, Sleep Initiation and Maintenance Disorders, Mental Disorders, Dyssomnias
- Trial name
- NCT00561821
- Testing
- Esmirtazapine
- Volunteers
- 538 people
- Sponsor
- Merck Sharp & Dohme LLC
Obstructive Sleep Apnea
Domiciliary Diagnosis and Follow up in Obstructive Apnoea Syndrome
The aim of the investigators study was to evaluate the effectiveness of a home programme (diagnosis and follow-up) in patients with Obstructive Sleep Apnea (OSA) syndrome treated with CPAP and to analyze the cost of this approach.
- Trial name
- NCT01001858
- Testing
- Diagnosis and monitoring of OSA patients
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Hospital Universitario San Juan de Alicante
Idiopathic Hypersomnia
A Study of TAK-360 in Adults With Idiopathic Hypersomnia
Idiopathic Hypersomnia (IH) is a condition where people feel extremely sleepy during the day, especially in the morning, even if they sleep a lot at night.
- Trial name
- NCT06812078
- Testing
- TAK-360
- Where
- 29 sites in United States, France and 4 more
- Volunteers
- 96 people
- Sponsor
- Takeda
Sleep Apnea Syndromes
Left Atrial Volume and Function Evaluation in Patients With Obstructive Sleep Apnea
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in left atrial morphology and function evaluated by echocardiography three dimensional
- Trial name
- NCT00570115
- Where
- Brazil
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Lung Diseases, Sleep Apnea Syndromes
Sleep Apnea in Elderly Male Twins
To conduct a genetic analysis of anatomic risk factors for sleep apnea in a well-characterized United States population-based registry of elderly male twins who have been successfully followed for the past 30 years.
- Conditions
- Lung Diseases, Sleep Apnea Syndromes, Obesity
- Trial name
- NCT00005525
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Sleep Apnea, Obstructive, Hypertension
Epidemiology and Intervention of Obstructive Sleep Apnea Based on Community
This observational study in a real-world community was designed to perform epidemiological investigation and assess effect of CPAP intervention of obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive, Hypertension, Obesity, Diabetes
- Trial name
- NCT03280914
- Testing
- Auto-CPAP
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Guangdong Provincial People's Hospital
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