Clinical trials: Sleep Disorders, Intrinsic
Restless Legs Syndrome
REST Study (CompRESsion Therapy for RLS)
This study in patients with restless leg syndrome (RLS) will evaluate the use of Cirvo™ therapy for the treatment of this disorder when applied to both legs.
- Trial name
- REST (NCT03852771)
- Testing
- Cirvo(TM) therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Radial Medical, Inc.
Temporomandibular Disorders (TMD)
Effects of a Biopsychosocial Approach Added to Physiotherapy in Temporomandibular Disorders
Temporomandibular disorders are conditions that affect the jaw joint and surrounding muscles and may cause pain, limited jaw movement, stress, sleep problems, and teeth grinding.
- Trial name
- TMD-BPS (NCT07320144)
- Testing
- Physiotherapy Program, Biopsychosocial Intervention
- Volunteers
- 40 people
- Sponsor
- Betül Özata
Insomnia, Traumatic Brain Injury
University of Colorado - Restoring Efficient Sleep After TBI
Sleep disturbance is a common condition following traumatic brain injury (TBI) and impairs recovery and quality of life. While efficacious interventions exist many are not accessible to all patients due to a variety of factors…
- Trial name
- CU-REST (NCT05683145)
- Testing
- Computerized Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Eastern Colorado Health Care System
COPD, Insomnia
Progressive Relaxation for COPD: Effects on Insomnia and Satisfaction
In the life model based on the activities of living developed by nursing theorists Roper, Logan, and Tierney, sleep is identified as one of the twelve essential activities.
- Trial name
- NCT06933602
- Testing
- relaxin
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ceylan Aksoy
Heart Failure, Sleep Apnea
Treatment of Cheyne Stocks Respiration With Adaptive Servo Ventilation and Bilevel Ventilators in Patients With Chronic Heart Failure
The overall purpose of this study is to determine the effects of adaptive servo ventilation (ASV) and bi-level ventilators on Cheyne-Stocks respiration (CSR).
- Trial name
- NCT00725595
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Apnea, Obstructive Sleep, Obesity
Association of Body Fluid Distribution With Obstructive Sleep Apnea in Pregnant Women With Body Mass Index ≥ 40 kg/m2
Obstructive Sleep apnea (OSA) is a common and underdiagnosed condition in obese pregnant women with serious and life-threatening complications to the mother and baby.
- Trial name
- NCT04187612
- Testing
- Bioelectrical Impedance Analysis (BIA)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Insomnia
Schumann Resonance and Insomnia
The double-blinded and randomized study evaluated the effectiveness and side effects of a novel non-invasive treatment, Schumann resonance (SR), in treating insomnia.
- Trial name
- NCT05053919
- Testing
- Schumann resonance sleep device
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Narcolepsy
Observational Study to Evaluate Risks of Side Effects, Drug Abuse and Dependence in Patients Who Received Xyrem ® on Prescription
Patients will be followed up for max 18 months. Information on the Adverse Events and potential misuse or abuse of Xyrem ® will be collected.
- Trial name
- NCT00244465
- Where
- 41 sites in Austria, Belgium and 7 more
- Volunteers
- 750 people
- Sponsor
- UCB Pharma
Transient Insomnia
A Trial to Assess Consumer Self-Selection and Use of Gabapentin for Occasional Sleeplessness in an Over-the-Counter Environment
The purpose of this study is to assess consumers' behaviors related to gabapentin self- selection and use, relative to warnings and directions for use, as described in the proposed over-the-counter (OTC) product label.
- Trial name
- NCT00659100
- Testing
- Gabapentin
- Where
- 35 sites in United States
- Volunteers
- 1,254 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Sleep Disordered Breathing
Evaluation of Sleep Disordered Breathing Following Ambulatory Surgery
Obstructive sleep apnea (OSA) is a relatively common medical condition that includes upper-airway obstruction and consequent cessation of breathing during sleep with significant associated other medical problems.
- Trial name
- NCT01851798
- Testing
- Home sleep test administered to all enrolled subjects
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Walter Reed National Military Medical Center
Chronic Pain, Insomnia
Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain
The purpose of this research study is to test whether Brief Behavioral Treatment for Insomnia (BBTI) delivered over the phone or Brief Mindfulness Training (BMT) delivered over the phone is better able to improve the symptoms of…
- Conditions
- Chronic Pain, Insomnia, HIV
- Trial name
- HIP HOP (NCT07270406)
- Testing
- Brief Behavioral Treatment for Insomnia (BBTI), Brief Mindfulness Training (BMT)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Washington University School of Medicine
Respiratory Insufficiency, Sleep Disordered Breathing
Adjustment of Mask Pressure, for Bilevel Positive Airways Pressure Therapy, by Automated Algorithm
The aim of the study is to test the hypothesis that an automated algorithm for desired mask pressure improves breathing pattern and sleep quality in patients with hypercapnic ventilatory failure.
- Trial name
- NCT01403584
- Testing
- AutoVPAP with addition of AutoEPAP, AutoVPAP with EPAP manually selected
- Where
- Germany
- Volunteers
- 21 people
- Sponsor
- ResMed
Rare Diseases, Fatigue
Fatigue, Depressive Disorders and Insomnia in Adult Patients with Marfan Syndrome and Ehlers-Danlos Syndrome: Survey
The goal of this observational study is to describe and assess the presence of perceived fatigue in subjects with MFS and EDS. the main question it aims to answer through the FSS instrument is: The relationship of fatigue with…
- Conditions
- Rare Diseases, Fatigue, Insomnia, Depression
- Trial name
- FAMED (NCT05712564)
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 282 people
- Sponsor
- IRCCS Policlinico S. Donato
Heart Failure, Obstructive Sleep Apnea
Sleep Apnea in Heart Failure With Preserved Ejection Fraction
This is a prospective interventional study to better understand i) the prevalence of Obstructive Sleep Apnea (OSA) in Heart Failure with preserved Ejection Fraction (HFpEF), ii) its hemodynamic correlates, and iii) the impact of…
- Trial name
- NCT05008432
- Testing
- Home sleep apnea testing
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Mayo Clinic
Neuropathic Pain, Insomnia
Sleep and Neuropathic Pain - Intervention Study on Pregabalin
The goal of this clinical study is to study sleep and its microstructure in neuropathic pain patients who have or who do not have a clinically significant sleep disturbance, before and during (after 1-month stabile dosage)…
- Conditions
- Neuropathic Pain, Insomnia, Sleep Disorder
- Trial name
- NCT06155916
- Testing
- Pregabalin
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Helsinki University Central Hospital
Obstructive Sleep Apnea
TipTraQ Home Sleep Test Validation Study, Duke
A validation study has been designed to assess the performance of a home sleep test device, TipTraQ, for screening sleep apnea. The study involves participants wearing the TipTraQ device on their fingertip during a traditional…
- Trial name
- NCT06351878
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- PranaQ Pte. Ltd.
Cardiovascular Diseases, Hypertension
Impact of Sleep Disordered Breathing in Older Adults
To test the hypothesis that clinically inapparent sleep-disordered breathing was associated with blood pressure elevation, impairment of health-related quality of life, and depression.
- Conditions
- Cardiovascular Diseases, Hypertension, Depression, Sleep Apnea Syndromes
- Trial name
- NCT00005378
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Snoring, Obstructive Sleep Apnea
Prospective Evaluation of a Palato-Pharyngeal Implant System (PPIS) Obstructive Sleep Apnea Syndrome (OSAS)
Prospective Evaluation of a Palato-Pharyngeal Implant System (PPIS) for the Treatment of Snoring and Obstructive Sleep Apnea Syndrome (OSAS): A Pilot Study.
- Trial name
- NCT03640793
- Testing
- Implantation
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Medartis AG
Anxiety, Intensive Care Unit Syndrome
Virtual Reality to Reduce the Anxiety in Critically Ill Patient
Anxiety and discomfort generated by repeated medical cares and invasive procedures can induce cognitive disorders in critical illness survivors as post-traumatic stress disorder.
- Trial name
- VRAI (NCT06747793)
- Testing
- Virtual Reality
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Toulouse
Postoperative Pain, Breast Cancer Surgery
Postoperative Pain, Central Sensitization, and Sleep Quality in Breast Cancer Surgery Patients
This prospective observational study aims to investigate whether preoperative central sensitization and sleep quality are associated with acute postoperative pain levels in patients undergoing breast cancer surgery.
- Conditions
- Postoperative Pain, Breast Cancer Surgery, Central Sensitization, Sleep Quality
- Trial name
- NCT07077421
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Istanbul University - Cerrahpasa
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