Clinical trials: Sleep Disorders, Intrinsic
Mood, Cognitive Performance
The Effects of A Proprietary Spearmint Extract on Cognitive Performance
This study was designed to evaluate the chronic effects of a proprietary spearmint extract over 90 days of supplementation on aspects of cognitive performance (cognitive function and active reaction time), subjective mood, and…
- Conditions
- Mood, Cognitive Performance, Sleep
- Trial name
- NCT02518165
- Testing
- Proprietary spearmint extract
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Insomnia, Depressive Disorder, Major
A Study of Eszopiclone in Subjects With Insomnia Related to Major Depressive Disorder
The purpose of this study is to evaluate subjective sleep efficacy in subjects with insomnia related to major depressive disorder.
- Trial name
- NCT00368030
- Testing
- Eszopiclone
- Where
- 65 sites in United States
- Volunteers
- 545 people
- Sponsor
- Sumitomo Pharma America, Inc.
Sleep Initiation and Maintenance Disorders, Stress Disorders, Posttraumatic
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Post-traumatic stress disorder (PTSD) is a common consequence of combat that can result in trauma-related hyperarousal and sleep disturbances.
- Trial name
- NCT03642028
- Testing
- Suvorexant
- Where
- 4 sites in United States
- Volunteers
- 190 people
- Sponsor
- VA Office of Research and Development
Stroke, Sleep Apnea Syndrome (OSAS)
Sleep and Stroke Rehabilitation Study
The study aims to map sleep disorders and their impact on the ability to engage in an active daily life among people who have had a stroke, with particular focus on how sleep apnea can be identified.
- Conditions
- Stroke, Sleep Apnea Syndrome (OSAS), Insomnia, Excessive Daytime Sleepiness
- Trial name
- SnSRehabS (NCT07579871)
- Where
- Sweden
- Volunteers
- 226 people
- Sponsor
- Malin Eleonora av Kák Gustafsson, MD, PhD
Obstructive Sleep Apnea
Obstructive Sleep Apnea Treatment With CPAP With and Without the Use of Expiratory Pressure Relief Technology
Expiratory pressure relief (EPR) is a technology designed to improve patient comfort during continous positive airway pressure (CPAP) treatment for obstructive sleep apnea (OSA).
- Trial name
- OSAEPR (NCT05219591)
- Testing
- EPR
- Where
- Brazil
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Sleep Initiation and Maintenance Disorders, Breast Cancer
Acupuncture for Sleep Disruption in Cancer Survivors
The proposed study will recruit 60 women with breast cancer who finished undergoing treatment who complain of persistent insomnia problems that began with onset of their cancer diagnosis.
- Trial name
- NCT01162018
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Stanford University
COPD (Chronic Obstructive Pulmonary Disease), Obesity Hypoventilation Syndrome (OHS)
The Effect of Mask Design on Ventilation Parameters in COPD and OHS Patients on Long-term Home Non-invasive Ventilation. An Experimental Study.
Chronic obstructive pulmonary disease (COPD) and obesity hypoventilation syndrome (OHS) are respiratory conditions that disrupt normal breathing.
- Trial name
- NCT06972589
- Testing
- Investigational Mask, Conventional mask
- Where
- New Zealand
- Volunteers
- 20 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea, Postoperative Respiratory Complications
A Multicenter Retrospective Analysis of Postoperative Respiratory Complications in Children With Obstructive Sleepapnea
This retrospective observational study aims to evaluate postoperative respiratory complications (PORC) after (adeno)tonsillectomy in children with OSA.
- Conditions
- Obstructive Sleep Apnea, Postoperative Respiratory Complications, Adenotonsillectomy, Child Obesity
- Trial name
- MRA PORC (NCT07305168)
- Where
- 2 sites in Belgium, Hungary
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Insomnia, Primary, Major Depressive Disorder
Sleep To Reduce Incident Depression Effectively
This project will assess the effectiveness of a stepped-care model (i.e. digital Cognitive Behavioral Therapy for Insomnia (dCBT-I) followed by face-to-face CBT-I) in improving severity of insomnia and sleep outcomes in an…
- Conditions
- Insomnia, Primary, Major Depressive Disorder, Rumination
- Trial name
- STRIDE (NCT03322774)
- Testing
- digital Cognitive Behavioral Therapy for Insomnia, face-to-face Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education Control
- Where
- United States
- Volunteers
- 1,237 people
- Sponsor
- Henry Ford Health System
Posttraumatic Stress Disorder, Insomnia
Stress, Sleep and Cardiovascular Risk
We are evaluating a model where trauma exposure and threatening environments elicit nocturnal vigilance and sleep-related fears that compromise the healthy reduction of autonomic arousal during sleep which in turn stimulates…
- Trial name
- NCT03487991
- Testing
- Personalized sleep intervention
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Howard University
Sleep Apnea
Mapping for Acute Transvenous Phrenic Nerve Stimulation Study
The Mapping for Transvenous Phrenic Nerve Stimulation Study (MAPS) is being conducted to evaluate the feasibility of transvascular stimulation of phrenic nerves via an electrophysiology (EP) catheter advanced into the great veins.
- Trial name
- MAPs (NCT01981590)
- Testing
- Stimulating the phrenic nerve intravenously using high frequency electrical pulses using an EP catheter connected to external pulse stimulator.
- Where
- 2 sites in Netherlands, Sweden
- Volunteers
- 15 people
- Sponsor
- Medtronic BRC
Insomnia
An Investigational Study of MK0928 in Adult Outpatients With Insomnia (0928-014)(COMPLETED)
The purpose of this study is to evaluate the safety and effectiveness of MK0928 for insomnia (a sleep disorder).
- Trial name
- NCT00103818
- Testing
- gaboxadol
- Volunteers
- 900 people
- Sponsor
- H. Lundbeck A/S
Bipolar Disorder (BD)
Pain, Sleep Quality, Eating Habits and Physical Activity Level in Patients With Bipolar Disorder
Bipolar disorder (BD) is a complex condition characterized by recurrence of mania, hypomania, and depression. It is characterized by changes in daily life activities, sleep status, focus problems, and cognitive fluctuations.
- Trial name
- NCT06954350
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kutahya Health Sciences University
Obstructive Sleep Apnea (OSA), Metabolic Dysfunction-Associated Steatotic Liver Disease
FIB-4 Index, Sleep Apnea Severity, and Nocturnal Hypoxemia
This retrospective study evaluates whether the Fibrosis-4 (FIB-4) index is associated with the severity of obstructive sleep apnea (OSA) and nighttime oxygen desaturation.
- Trial name
- FIB-4-OSA (NCT07798518)
- Where
- Turkey (Türkiye)
- Volunteers
- 373 people
- Sponsor
- Hisar Intercontinental Hospital
Depression, Insomnia
Sleep Therapy for Insomnia and Depression
In this study we are testing 2 different forms of sleep therapy to help people with insomnia and depression. As part of the study, you receive 1 of these 2 sleep therapies.
- Trial name
- NCT02943278
- Testing
- Intensive Sleep Retraining, Sleep Hygiene
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Michigan
Sleep Initiation and Maintenance Disorders
Mechanisms of Change in Cognitive Behavioral Therapy for Insomnia (CBTi)
The purpose of this study is to investigate the mechanisms of change in Cognitive Behavioral Therapy for insomnia (CBTi) in a sample of adults aged 50-65.
- Trial name
- CBTi (NCT05226585)
- Testing
- In-Person Cognitive Behavioral Therapy for Insomnia, Telehealth Cognitive Behavioral Therapy for Insomnia, Internet Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- University of Arizona
Sleep Disturbance, Insomnia
Brief Telehealth CBT-I Intervention in the Context of the COVID-19 Pandemic
The purpose of this study is to investigate whether an empirically validated treatment for insomnia (CBT-I) administered early in the course of sleep disturbance can prevent insomnia disorder or lessen negative mental health…
- Trial name
- NCT04409743
- Testing
- Remote Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Stanford University
Sleep Apnea, Central, Prader-Willi Syndrome
Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome
The aim of this study is to determine if treatment with Medical Air (21% oxygen in room air) compared to supplemental oxygen (100% oxygen) will lead to similar improvements in the central apnea-hypopnea index (CAHI) for infants…
- Trial name
- NCT03031626
- Testing
- Medical Air vs Oxygen
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- The Hospital for Sick Children
Chronic Insomnia, TBI (Traumatic Brain Injury)
The Effects of MBSR on Patients With TBI and Chronic Insomnia
To evaluate the effects of Mindfulness Based Stress Reduction (MBSR) as an adjunct to usual clinical care for treatment of stress and chronic insomnia for patients with mild to moderate traumatic brain injury (MTBI).
- Trial name
- NCT03560843
- Testing
- MBSR
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Lumbar Central Spinal Stenosis, Restless Legs Syndrome
Epidural Steroid Injection for Restless Legs Symptoms in Lumbar Stenosis
Lumbar central spinal stenosis (LCSS) is a common degenerative spinal disorder characterized by narrowing of the spinal canal, resulting in chronic low back pain, leg pain, and neurogenic claudication.
- Trial name
- NCT07637643
- Testing
- Lumbar Interlaminar Epidural Steroid Injection
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Saglik Bilimleri Universitesi
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.