Clinical trials: Sleep Disorders, Intrinsic
Sleep Apnea, Obstructive
Influence of Different Methods of Measurement in the Accuracy of DES-OSA and P-SAP Scores
DES-OSA and P-SAP scores have been validated to detect OSA (Obstructive Sleep Apnea). One item of P-SAP and DES-OSA is the measurement of neck circumference.
- Trial name
- NCT03047421
- Testing
- Comparison of accuracy of DES-OSA and P-SAP scores
- Where
- Belgium
- Volunteers
- 1,682 people
- Sponsor
- Astes
Narcolepsy, Narcolepsy Type 1
Decreasing Nightmares in Adults With Narcolepsy
The purpose of this clinical trial is learn whether a behavioral (non-medication) treatment can reduce nightmares in adults with narcolepsy. All participants will receive the treatment and will complete three assessments.
- Conditions
- Narcolepsy, Narcolepsy Type 1, Narcolepsy With Cataplexy, Narcolepsy Without Cataplexy
- Trial name
- DAWN (NCT06383806)
- Testing
- Imagery Rehearsal Therapy (IRT)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Sleep, Wearable Technology
Effects of PeptiSleep on Sleep Quality in Healthy Adults
Examining the effects of PeptiSleep, a plant-based sleep aid, on sleep quality in healthy adults
- Conditions
- Sleep, Wearable Technology, Cortisol, Healthy Participants
- Trial name
- NCT07258433
- Testing
- PeptiSleep, Micro-crystalline cellulose
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Obstructive Sleep Apnea
Pharmacological Activation of HMN for OSA
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. OSA patients show a marked reduction in upper airway (UA) dilator muscle activity at sleep onset and this phenomenon…
- Trial name
- OSA12 (NCT03640052)
- Testing
- LTM1201L, LTM1201LN, LTM1201LB
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Brigham and Women's Hospital
Sleep Quality
"Eye Masks and Post-Surgical Sleep Quality"
The aim of this study is to evaluate the impact of postoperative eye mask usage on sleep quality in patients who have undergone gynecological surgery.
- Trial name
- SEM (NCT05988164)
- Testing
- Eye Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Restless Legs Syndrome
Assess Efficacy and Safety of the Dopamine Agonist Pramipexole Versus Levodopa / Benserazide (Madopar® DR) in Patients With Restless Legs Syndrome
The primary objective of this study is to determine that pramipexole (Sifrol) 0.25 mg to 0.75 mg daily is not inferior to levodopa 100 mg to 300 mg (in combination with benserazide 25mg to 75mg = Madopar DR) daily in the…
- Trial name
- NCT00144209
- Testing
- pramipexole, levodopa in combination with benserazide
- Where
- 6 sites in Switzerland
- Volunteers
- 58 people
- Sponsor
- Boehringer Ingelheim
Cognitive Deficits, Mild
Microbiome-Targeted Enhancement of Neurocognition With Probiotics-Riboflavin Combination
This randomized, double-blind, placebo-controlled trial will evaluate whether 12 weeks of supplementation with the probiotic Lactobacillus rhamnosus GG combined with colon-delivered riboflavin will improve cognitive performance…
- Trial name
- MENTOR (NCT07410052)
- Testing
- Experimental 1, Experimental 2
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Obstructive Sleep Apnea
Positioning of Surgical Patients With Sleep Apnea
The study aims to evaluate the effect of non-supine positioning in the treatment of surgical patients with obstructive sleep apnea.
- Trial name
- NCT02123238
- Testing
- bed positioning
- Where
- United States
- Sponsor
- Englewood Hospital and Medical Center
Insomnia Related to Another Mental Condition
Association Between the Quality of the Therapeutic Alliance and the Response to ChronoS Therapy
PREDI-CHRONOS is an ancillary study of the CHRONOS project (NCT07180290) The goal of this study is to measure the association between therapeutic alliance and the clinical response to the CHRONOS therapy.
- Trial name
- PREDI-CHRONOS (NCT07202338)
- Testing
- CHRONOS therapy
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Centre Hospitalier St Anne
Narcolepsy 1, Kleine-Levin Syndrome
Microglial Activation in Narcolepsy Type 1 and Kleine-Levin Syndrome: Positron Emission Tomography (PET) Study in [18F] DPA-714
Type 1 narcolepsy (NT1) is a chronic sleep disorder caused by the selective and irreversible loss of neurons from the hypothalamus, which synthesizes a neurotransmitter: hypocretin (Hcrt) / orexin.
- Trial name
- NARCOGLIE (NCT03754348)
- Testing
- PET scan with tracer injection [18F] DPA-714
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Montpellier
Insomnia
Cognitive-Behavioural Therapy (CBT) for Insomnia Via Internet or Telehealth
Cognitive-Behavioural Therapy (CBT) is an effective treatment for chronic insomnia, which is a prevalent and costly problem. This pilot study will compare the effectiveness of two brief (6 week) psychological interventions…
- Trial name
- NCT01162655
- Testing
- Cognitive-behavioral therapy for Insomnia (CBT)
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- University of Manitoba
Obstructive Sleep Apnea
Precision Health and Smart Telerehabilitation in OSA
This study aims to improve treatment strategies for Obstructive Sleep Apnea (OSA), a disorder characterized by recurrent upper airway collapse during sleep, resulting in reduced oxygenation, sleep fragmentation, and excessive…
- Trial name
- NCT07254026
- Testing
- Surgery, Continuous positive airway pressure, Oropharyngeal Exercise with diary
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Cheng-Kung University Hospital
Sleep Quality, Sedentary Lifestlye
Impact of a Physical Activity Intervention on Sleep Quality, Mental and Physical Well-Being in Health Sciences Students
This randomized controlled trial aims to compare the effects of a regular weekly physical activity program versus a "Weekend Warrior" activity pattern on sleep quality, physical well-being, and mental well-being in sedentary…
- Conditions
- Sleep Quality, Sedentary Lifestlye, Physical Activity, Well-being
- Trial name
- NCT07140185
- Testing
- Regular Weekly Physical Activity Program, Weekend Warrior Physical Activity Program
- Where
- Tunisia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Sfax
Healthy Subjects, Restless Legs Syndrome
Infra-slow Oscillations During Sleep
In this study the investigators plan to systematically characterise infra-slow EEG oscillations during sleep, explore their relationship to the microstructure of sleep, and investigate its role in the physiology and…
- Conditions
- Healthy Subjects, Restless Legs Syndrome, Periodic Limb Movements During Sleep
- Trial name
- SleepD-ISO (NCT02532608)
- Testing
- Acute sleep deprivation
- Where
- Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Stephany Fulda
Labor Progression, Pregnancy
Effects of Sleep Quality, Anxiety, and Digital Behavior on Labor Progression in Term Primiparous Women: A Prospective Observational Study
This prospective observational study evaluates whether maternal sleep quality, anxiety levels, and nighttime digital behavior are associated with labor progression among term primiparous women.
- Trial name
- SAD-LABOR (NCT07299708)
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Primary Insomnia
Safety and Efficacy of Chronic Hypnotic Use
The purpose of the study is to determine how safe and effective it is for people with insomnia to use zolpidem on a nightly basis for one year.
- Trial name
- NCT01006525
- Testing
- zolpidem
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Obstructive Sleep Apnea
Change in C-reactive Protein (CRP) in Men and Women With Sleep Apnea After Continuous Positive Airway Pressure (CPAP)
C-reactive protein (CRP) is directly implicated in atherogenesis and associated cardiovascular morbidity in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT01365832
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Greece
- Volunteers
- 436 people
- Sponsor
- University of Crete
Insomnia
Brief Versus Standard Cognitive Behavioral Therapy for Insomnia in Veterans
Insomnia is a common condition in Veterans, with prevalence rates as high as 53% among treatment-seeking Veterans. Chronic untreated insomnia is associated with increased risk for functional impairment, psychiatric illness…
- Trial name
- NCT05724498
- Testing
- Brief CBT-I, Standard CBT-I
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea
Prospective Use of Awake Endoscopy for Inspire Activation
The aim of this study is to examine a new method of device configuration for the Inspire upper airway stimulator. First, the investigators will attempt to determine optimal configuration by quantifying changes in upper airway…
- Trial name
- NCT03990298
- Testing
- Awake endoscopy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pennsylvania
Sleep Apnea Syndromes, Oxidative Stress
Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea
Sleep-disordered breathing (SDB) is a condition in which a person experiences frequent breathing pauses during sleep, also known as sleep apnea.
- Conditions
- Sleep Apnea Syndromes, Oxidative Stress, Cardiovascular Diseases
- Trial name
- SASS (NCT00607893)
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
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