Clinical trials: Sleep Disorders, Intrinsic
Hemodialysis-Associated Pruritus, Malnutrition-Inflammation-Cachexia Syndrome
Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients
In this study, the investigators aimed to observe the effects of medium cut-off dialysis filters and high-flux dialysis filters on malnutrition inflammation score, uremic itching, restless leg syndrome, anemia, and ESA treatment…
- Conditions
- Hemodialysis-Associated Pruritus, Malnutrition-Inflammation-Cachexia Syndrome, Restless Legs Syndrome, Anemia of Chronic Kidney Disease
- Trial name
- NCT05698420
- Testing
- Dialysis using the Theranova-400 device., Dialysis using the FX80 device.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Insomnia
A Long Term Safety Study of Suvorexant in Participants With Primary Insomnia (MK-4305-009 AM3)
This study will establish the safety and tolerability of suvorexant (MK-4305) when administered for up to 14 months. Participants will be randomized to receive suvorexant or placebo for a 12-month double-blind (DB) Treatment…
- Trial name
- NCT01021813
- Testing
- Suvorexant
- Volunteers
- 781 people
- Sponsor
- Merck Sharp & Dohme LLC
Restless Legs Syndrome
Drug Drug Interaction Study With Gabapentin Enacarbil and Morphine
This double-blind study will evaluate the pharmacokinetics of a single dose of morphine or gabapentin derived from gabapentin enacarbil (GEn) after administration of morphine and GEn alone and in combination as well as the…
- Trial name
- NCT01476124
- Testing
- GEn 600 mg, Morphine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- XenoPort, Inc.
Heart Failure With Normal Ejection Fraction, Sleep Apnea
Adherence to ASV Therapy in Heart Failure With Preserved Ejection Fraction Feasibility Study
This study is designed to demonstrate feasibility of study conduct and that acceptable adherence to adaptive servo-ventilation (ASV) therapy can be achieved in recently hospitalized HFpEF patients with moderate to severe sleep…
- Trial name
- CAT-PEF (NCT03195660)
- Testing
- ASV Therapy
- Where
- 4 sites in United States, Germany
- Volunteers
- 6 people
- Sponsor
- ResMed
Intertrochanteric Fractures, Hip Fractures
Liposomal Bupivacaine Fascia Iliaca Block for Perioperative Sleep Quality in Elderly Patients With Intertrochanteric Fracture
Older adults with hip fracture often experience severe pain before and after surgery. This pain can cause anxiety and poor sleep, and may increase the risk of postoperative delirium (sudden confusion after surgery).
- Conditions
- Intertrochanteric Fractures, Hip Fractures, Sleep Disturbance, Postoperative Delirium
- Trial name
- NCT07892859
- Testing
- Liposomal Bupivicaine, Saline Solution (NaCl 0,9%)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Li Xiaoyuan
Sleep Apnea
The Roles of Prostanoids in Patients With Sleep Apnea Syndrome
The purpose of this study is to evaluate the relationships between prostanoids and various outcomes such as sleep disturbance, hypertension and arteriosclerosis in patients with sleep apnea syndrome(SAS).
- Trial name
- NCT01015872
- Testing
- CPAP treatment
- Where
- Japan
- Volunteers
- 46 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Fatigue, Occupational Stress or Workplace Stress
Effect of Agarwood (Aquilaria Sinensis) Inhalation Aromatherapy on Workplace Fatigue and Sleep Quality Among Hospital Employees: A Randomized Controlled Trial
Hospital staff often experience workplace fatigue and poor sleep quality, which can harm their health, reduce job performance, and increase risks to patient safety.
- Conditions
- Fatigue, Occupational Stress or Workplace Stress, Sleep Quality
- Trial name
- NCT07188831
- Testing
- Agarwood Aromatherapy Inhalation
- Volunteers
- 78 people
- Sponsor
- Da-Yeh University
Insomnia
Cognitive Behavioral Therapy for Insomnia: Face-to-Face Versus Telemedicine
The purpose of this study is to compare the effectiveness of Cognitive-Behavioral Therapy (CBT) for insomnia conducted face-to-face with a therapist versus CBT for insomnia conducted using Internet-based videoconference…
- Trial name
- NCT03293745
- Testing
- Face to Face CBT-I (F2F), Telemedicine CBT-I (TM)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Michigan
Older Adults (65 Years and Older), Older Adults Without Any Specific Clinical Condition
The Effect of Virtual Reality in Older Adults
This research will be conducted to examine the effects of virtual reality on sleep quality and comfort in older adults. This research will be conducted as a single-blind, randomized controlled experimental study with a…
- Trial name
- NCT07499245
- Testing
- using virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kafkas University
Postoperative Complications, Fatigue
Melatonin Treatment After Laparoscopic Cholecystectomy
Circadian disturbances occur after surgery. A double blinded, placebo controlled randomized clinical trial was made to investigate effects of melatonin on postoperative fatigue, sleep disturbances and general wellbeing.
- Conditions
- Postoperative Complications, Fatigue, Dyssomnias
- Trial name
- NCT00113906
- Testing
- melatonin
- Where
- 2 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Insomnia, Depression
The Sleep Course: An Online Sleep Intervention for Adults With Self-reported Sleep Difficulties
This study evaluates an internet-delivered cognitive behavioural therapy for insomnia (ICBTi) intervention, known as the Sleep Course, within a routine online therapy clinic (the Online Therapy Unit).
- Conditions
- Insomnia, Depression, Anxiety
- Trial name
- NCT06745349
- Testing
- Sleep Course
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Regina
Pregnancy, Obstructive Sleep Apnea
The Effect of OSA on Pregnancy and Fetal Outcomes
This cohort study aims to investigate the impact of obstructive sleep apnea hypopnea syndrome (OSA) on pregnancy and fetal outcomes.
- Trial name
- NCT06391138
- Testing
- Continuous Positive Airway Pressure
- Volunteers
- 500 people
- Sponsor
- Peking University First Hospital
Obstructive Sleep Apnea, Diabetes Mellitus
The Effect of Lifestyle Intervention Versus Gastric Bypass on Various Comorbidities in Morbidly Obese Subjects
This follow up study (>1 year) aims to compare the effects of lifestyle intervention and gastric by pass surgery on various comorbidities associated with morbid obesity.
- Conditions
- Obstructive Sleep Apnea, Diabetes Mellitus, Hypertension
- Trial name
- NCT00273104
- Testing
- Bariatric surgery, Intensive lifestyle intervention
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- The Hospital of Vestfold
Olfactory Disorder, Olfaction Disorders
Intranasal Injection of PRP Versus Saline for Treatment of Olfactory Dysfunction
This randomized clinical trial will evaluate the benefit of platelet-rich plasma (PrP) in the treatment of olfactory dysfunction.
- Conditions
- Olfactory Disorder, Olfaction Disorders, Olfactory Nerve Injuries, Olfactory Nerve Disorder
- Trial name
- NCT04406584
- Testing
- Injection into olfactory cleft
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Sleep Bruxism, Adult, Splints
Occlusal Splints in the Treatment of Sleep Bruxism
Occlusal splints are employed in the treatment of sleep bruxism. These appliances decrease sleep-related actions and damages bruxism, like grinding, tooth-wear, headache, and temporomandibular joint disorders.
- Conditions
- Sleep Bruxism, Adult, Splints, Sleep
- Trial name
- bruxism (NCT04934449)
- Testing
- Occlusal splint
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Obesity Hypoventilation Syndrome (OHS), Chronic Obstructive Lung Disease
Telemedical Assistance in Automatic Titration of Oxygen for Intensive Care Patients
The goal of this clinical trial is to clinically validate a system for the monitoring of patients' respiratory function and automated oxygen treatment proposal using non-invasive ventilation devices in the treatment of intensive…
- Conditions
- Obesity Hypoventilation Syndrome (OHS), Chronic Obstructive Lung Disease, Interstitial Lung Disease, Pneumonia
- Trial name
- Smartassistant (NCT06090149)
- Testing
- PHASE 1 Lowenstein medical BiLevel Prisma 25ST device: withount oxygen support., PHASE 2. Continous/Bilevel positive airway presure with additional oxygen support by Devilbiss 525 KS oxygen concentrator
- Where
- Latvia
- Volunteers
- 30 people
- Sponsor
- Pauls Stradins Clinical University Hospital
Sleep Apnea, End Stage Renal Disease
Impact of Different Dialysis on Sleep Apnea in Patients With Renal Failure
The purpose of this study is to determine whether hemodiafiltration, a new form of hemodialysis can improve sleep apnea in patients with end stage kidney disease.
- Trial name
- NCT00380848
- Testing
- Hemodiafiltration
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Iron Deficiency
Intravenous High Dose Iron in Blood Donors
2-3% of the population participates in blood donation programmes. Traditionally, safety issues in transfusion medicine have been concentrating on product and recipient safety.
- Trial name
- IronWoMan (NCT01787526)
- Testing
- ferric carboxymaltose, oral iron
- Where
- Austria
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Sleep Apnea
Validation of the Diagnostic Performance of the Sleep Apnea Syndrome by the Withings HWA09 Device
Sleep Apnea Syndrome (SAS) is a common pathology affecting between 4 and 8% of the general population. It aggravates morbidity and cardio-metabolic mortality and is responsible for accidents related to vigilance disorders.
- Trial name
- VPASH (NCT04496843)
- Testing
- HWA09 Measurement
- Where
- 2 sites in Belgium, France
- Volunteers
- 220 people
- Sponsor
- Withings
Insomnia
Efficacy and Safety of Two Doses of Hipnos in the Treatment of Adults With Insomnia
The purpose of this study is to evaluate the efficacy and safety of three doses of Hipnos medication in adults with insomnia.
- Trial name
- NCT03814135
- Testing
- Hipnos 3, Hipnos 5
- Sponsor
- EMS
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