Clinical trials: Sleep Disorders, Intrinsic
Diabetes, Depression
e-Pharmacovigilance II - Surveillance for Safety and Effectiveness - Calling for Earlier Detection of Adverse Reactions
Specific Aim 1: To develop a patient-reported, EHR-integrated system to actively monitor the safety and effectiveness of treatment for patients taking FDA-approved medications for one of four common chronic conditions (diabetes…
- Conditions
- Diabetes, Depression, Insomnia, Hypertension
- Trial name
- CEDAR (NCT02087293)
- Testing
- Intervention arm - automated call and phone-based pharmacist counseling
- Where
- United States
- Volunteers
- 38,400 people
- Sponsor
- Brigham and Women's Hospital
Anxiety Disorders, Major Depression
CBT vs RTW Intervention for Patients With Common Subclinical Mental Illness in Primary Care
Background: Common mental illness, such as anxiety disorders and depression, is the main cause for sick leave in Sweden. Cognitive behavior therapy (CBT) has been shown to be effective in alleviating target symptoms of these…
- Conditions
- Anxiety Disorders, Major Depression, Stress Disorders, Primary Insomnia
- Trial name
- NCT01667809
- Testing
- Cognitive behavior therapy, Return to work
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Karolinska Institutet
Obstructive Sleep Apnea
Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy
Obstructive sleep apnea (OSA) is a disorder where a person has recurrent choking episodes during sleep. Surgery can treat OSA and drug induced sleep endoscopy (DISE) is a procedure that surgeons use to evaluate the throat while a…
- Trial name
- DISE-Pulm (NCT05350332)
- Testing
- Negative Pressure Ventilator, Pulmonary Function Testing (PFT), Transcutaneous Phrenic Nerve Stimulation
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Emory University
Insomnia
E-aid Cognitive Behavior Therapy for Insomnia to Prevent Transition From Acute Insomnia to Chronic Insomnia in China
Acute insomnia is one of the most common sleep disorders. Online cognitive behavioral therapy for insomnia (e-aid Cognitive Behavioral Therapy for Insomnia, eCBTI) has received wide attention in recent years.
- Trial name
- NCT03302455
- Testing
- eCBTI
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Sildenafil, Sleep Apnea
The Effect of Sildenafil on Sleep-Disordered Breathing in Obese Patients With Sexual Dysfunction
Sildenafil has been shown to aggravate sleep-disordered breathing in patients with severe obstructive sleep apnea. The aim of the present study is to examine the frequency of sleep-disordered breathing in obese patients who are…
- Conditions
- Sildenafil, Sleep Apnea, Sexual Dysfunction, Obesity
- Trial name
- NCT00893191
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Obstructive Sleep Apnea Syndrome
Cost-utility Study of Continuous Positive Airway Pressure Treatment in Obstructive Sleep Apnea Syndrome Patients
The purpose of this study is to estimate the cost-utility of continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea (OSA) patients in Sao Paulo city, Brazil, after 3 years of treatment and to estimate the…
- Trial name
- NCT01590420
- Testing
- CPAP S8- Scape / Resmed
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Sleep-disordered Breathing, Chronic Heart Failure
Validation of the "ApneaScan" Algorithm for the Detection of Sleep Disordered Breathing in Chronic Heart Failure
A prospective observational multi-centre study for the validation of the ApneaScan algorithm (integrated in ICD devices (with or without cardiac resynchronization therapy function) of the "Incepta" series for the screening of…
- Trial name
- VASA (NCT01979120)
- Where
- 14 sites in Austria, Germany and 2 more
- Volunteers
- 200 people
- Sponsor
- Dr. Christoph Schukro
Sleep Disturbance, Insomnia
The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS
This two-phase pilot study will test the feasibility of a "combined chronotherapy" (CC) intervention consisting of morning bright light therapy (BLT) and evening blue light blocking (BLB), administered daily for 4 weeks in…
- Conditions
- Sleep Disturbance, Insomnia, Acute Coronary Syndrome
- Trial name
- NCT05299723
- Testing
- BLT Intervention, BLB Intervention, Sleep Hygiene Education
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Columbia University
OSAHS, Gastrointestinal Endoscopy
Observation of Clinical Effect of New Oropharyngeal Airway in Patients With OSHAS During Painless Gastroenteroscopy
the(obstructivesleepapneahypoapneasyndromeOSAHS) is a kind of to sleep appear periodically in the process of syndrome characterized by partial or complete obstruction of upper respiratory tract.Patients with obstruction during…
- Conditions
- OSAHS, Gastrointestinal Endoscopy, Airway Complication of Anesthesia
- Trial name
- NCT06594380
- Testing
- Group using new oropharyngeal airway (experimental group), Endoscopic bite group (control group)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Obstructive Sleep Apnea, Snoring
A Disposable Device NAS to Treat Obstructive Sleep Apnea and Snoring
The purpose of this research study is to test a new approach for treating patients with obstructive sleep apnea and/or snoring. The new nasal device, nastent (NAS: nasal airway stent), appears to be a useful alternative or…
- Trial name
- NCT02928770
- Testing
- Nastent
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obstructive Sleep Apnea
Fentanyl Test in Children's Adenotonsillectomy
The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested…
- Trial name
- NCT02484222
- Testing
- Fentanyl
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Mild Obstructive Sleep Apnea, Snoring
Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea.
Snoring is a common problem caused by vibration of tissues in the throat region during sleep. Although snoring is sometimes dismissed as a minor nuisance rather than a medical disorder, several studies indicate that snoring can…
- Trial name
- MTASSA (NCT06587256)
- Testing
- Mouth Tape
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Neurologically Impaired, Irritable Mood
Effectiveness of Gabapentin on Chronic Irritability in Neurologically Impaired Children
This study is a prospective, randomized, double blind, placebo controlled, crossover clinical trial looking at whether gabapentin can provide symptom relief for chronic irritability in neurologically impaired children.
- Conditions
- Neurologically Impaired, Irritable Mood, Signs and Symptoms, Digestive, Sleeplessness
- Trial name
- NCT01675960
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Gillette Children's Specialty Healthcare
Post-Traumatic Stress Disorder
Evaluation of a Yoga Intervention for Post-Traumatic Stress Disorder
The main objective of this preliminary randomized controlled clinical trial is to establish efficacy and feasibility of a yoga-based treatment for PTSD in military veterans as compared to a delayed yoga treatment (waitlist…
- Trial name
- EYIPTSD (NCT00962403)
- Testing
- Yoga treatment
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Solid Tumors, Chemotherapy-induced Neutropenia
G-CSF-Related Bone Pain and Supportive Care Strategies in Patients With Solid Tumors
This prospective two-center observational cohort study evaluated G-CSF-related bone pain and multidimensional symptom burden in adults with solid tumors receiving chemotherapy and filgrastim prophylaxis.
- Trial name
- GCSF-PAIN (NCT07192770)
- Testing
- Filgrastim (G-CSF), Naproxen, Loratadine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 190 people
- Sponsor
- Ankara Etlik City Hospital
Heart Failure, Sleep Disorder
Prognostic Impact of Sleep Disorders in Patients : Pro-TSIC Study
Heart failure (HF) is a common and progressive condition associated with significant morbidity and mortality. Only 25-35% of patients survive 5 years after diagnosis.Sleep disorders are frequently found in this population with up…
- Conditions
- Heart Failure, Sleep Disorder, Insomnia
- Trial name
- Pro-TSIC (NCT04653883)
- Where
- France
- Volunteers
- 115 people
- Sponsor
- University Hospital, Montpellier
Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h), Intracranial Aneurysm Size
Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms
Patients with intracerebral aneurysm will be screened for sleep apnea using out of center polysomnography/polygraphy. Baseline blood pressure and medication will be assessed.
- Conditions
- Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h), Intracranial Aneurysm Size, Blood Pressure Medication, Comorbidities
- Trial name
- IESA (NCT02880059)
- Testing
- Cardiorepiratory Polygraphy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bonn
Alzheimer's Disease, Insomnia
Quetiapine for the Treatment of Insomnia in Alzheimer's Disease
The primary hypothesis is that quetiapine will improve sleep in persons with Alzheimer's Disease (AD), with higher doses producing greater total sleep time and sleep efficiency.
- Trial name
- NCT00232570
- Testing
- quetiapine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Vermont
Major Depressive Disorder, Insomnia
A Study of Eszopiclone Co-administered With Venlafaxine in Subjects With Major Depressive Disorder and Insomnia
To evaluate the antidepressant effect of adjunctive treatment with Eszopiclone in subjects receiving venlafaxine for the treatment of Major Depressive Disorder (MDD).
- Trial name
- NCT00435279
- Testing
- Eszopiclone, Venlafaxine
- Where
- 69 sites in Austria, Croatia and 8 more
- Volunteers
- 678 people
- Sponsor
- Sumitomo Pharma America, Inc.
Insomnia
Playing Cognitive Games For Older Adults With Insomnia
The purpose of this research is to look at the effects of computerized cognitive training on sleep, mental abilities (cognition), and other aspects of daytime functioning, such as mood, and arousal
- Trial name
- PLAY (NCT04282642)
- Testing
- Cognitive Training, WLC (Waitlist Control)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
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