Clinical trials: Sleep Disorders, Intrinsic
Obstructive Sleep Apnea, Diabetes Mellitus
Rapid Eye Movement Related OSA in Diabetic Versus Non-Diabetic Patients Treated With PCI
The primary objective of the Sleep and Stent II is to determine the prevalence of REM-OSA in DM versus non-DM patients undergoing clinically indicated PCI.
- Conditions
- Obstructive Sleep Apnea, Diabetes Mellitus, Coronary Artery Disease
- Trial name
- NCT03479788
- Where
- Singapore
- Volunteers
- 204 people
- Sponsor
- National University of Singapore
Obstructive Sleep Apnea Syndrome
Validation of Sleep Monitoring Algorithm Based on Smart Watches
In recent years, wearable devices are booming to enable not only the health monitoring but also the sleep efficiency assessment.
- Trial name
- NCT06696196
- Testing
- smart watches(wearable devices)
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Insomnia, Sleep Initiation and Maintenance Disorders
Zolpidem (Myslee) Post Marketing Study in Adolescent Patients With Insomnia - Evaluation With Polysomnography
To evaluate the efficacy of zolpidem for adolescent insomniacs with polysomnography
- Trial name
- NCT00653562
- Testing
- zolpidem
- Where
- 4 sites in Japan
- Volunteers
- 11 people
- Sponsor
- Astellas Pharma Inc
Chronic Obstructive Pulmonary Disease
Effects of Temazepam in Patients With Chronic Pulmonary Obstructive Disease
The purpose of this study is to evaluate the effects of temazepam during sleep and in daytime on dyspnea, gas exchange and sleep quality in patients with chronic obstructive pulmonary disease.
- Trial name
- NCT00245661
- Testing
- Temazepam
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Rijnstate Hospital
Restless Legs Syndrome
Simulated Driving Study in Restless Legs Syndrome
This study was a multi center, randomized, double blind, active and placebo controlled, parallel group study to assess simulated driving performance in XP13512 treated subjects with Restless Legs Syndrome (RLS).
- Trial name
- XP083 (NCT01332318)
- Testing
- XP13512, Diphenhydramine
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- XenoPort, Inc.
Sleep Apnea
Mapping for Acute Transvenous Phrenic Nerve Stimulation Study
The Mapping for Transvenous Phrenic Nerve Stimulation Study (MAPS) is being conducted to evaluate the feasibility of transvascular stimulation of phrenic nerves via an electrophysiology (EP) catheter advanced into the great veins.
- Trial name
- MAPs (NCT01981590)
- Testing
- Stimulating the phrenic nerve intravenously using high frequency electrical pulses using an EP catheter connected to external pulse stimulator.
- Where
- 2 sites in Netherlands, Sweden
- Volunteers
- 15 people
- Sponsor
- Medtronic BRC
Sleep Apnea Syndromes
Effectiveness of VistaO2 Device in Screening of Sleep Apnea/Hypopnea Syndrome
The high prevalence (9% in men and 4% in women) of sleep apnea / hypopnea syndrome (SAHS) in adults is now well documented as well as its cardiovascular repercussions.
- Trial name
- VISTAO2 (NCT01135303)
- Testing
- VistaO2 device
- Where
- 2 sites in France
- Volunteers
- 182 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Depression, Insomnia
Cognitive Behavioral Therapy for Insomnia with RTMS
Depression and insomnia occur together in a substantial number of patients. Transcranial magnetic stimulation (TMS) is an effective treatment for depression, but does not help insomnia symptoms in depressed patients.
- Trial name
- NCT04258618
- Testing
- CBT-I (Cognitive Behavioral Therapy for Insomnia) with rTMS, Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Medical University of South Carolina
Major Depressive Disorder (MDD) With Insomnia
Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia
Major Depressive Disorder (MDD) affects 5% of the global population and is the second leading cause of disability worldwide. Despite the widespread use of antidepressants, 50-60% of patients do not respond adequately after 8…
- Trial name
- CombiChronoS (NCT07120880)
- Testing
- AD + SHR + active LT and extended-release melatonin 2mg
- Where
- France
- Volunteers
- 184 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Bariatric Surgery Candidate
Impact of Bariatric Surgery in Obese Patients With and Without Obstructive Sleep Apnea Syndrome
It has been shown to date that obesity is associated with increased mortality and that weight loss significantly improves cardiovascular risk factors.
- Conditions
- Obesity, Bariatric Surgery Candidate, Apnea, Obstructive
- Trial name
- COLOSS (NCT04179188)
- Testing
- Bariatric surgery
- Where
- France
- Volunteers
- 400 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Insomnia
Study on the Efficacy and Safety of Anesthesia-Induced Sleep Therapy for Refractory Insomnia
The incidence of refractory insomnia is rising annually, with traditional therapies offering limited efficacy. Anesthesia-Induced Sleep (AIS), involving anesthetic infusion like dexmedetomidine, is emerging.
- Trial name
- NCT07255027
- Testing
- Dexmedetomidine and conventional oral drug, Conventional oral drug therapy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Insomnia, Metacognitive Beliefs
Insomnia After the COVID-19 Pandemic
The aim of this study is to investigate the levels of insomnia 3 months after (T2) the strict physical distancing government initiated physical distancing protocols related to the COVID-19 pandemic (T1).
- Conditions
- Insomnia, Metacognitive Beliefs, Anxiety, Depression
- Trial name
- NCT04443361
- Volunteers
- 5,000 people
- Sponsor
- University of Oslo
Mild Cognitive Impairment, Sleep Apnea, Obstructive
MCI: CPAP Treatment of OSA (Memories2)
The purpose of this project is to determine whether obstructive sleep apnea (OSA) treatment with positive airway pressure therapy (CPAP) can delay the progression of cognitive impairment in patients with amnestic Mild Cognitive…
- Trial name
- MCI:OSA (NCT03113461)
- Testing
- CPAP
- Where
- 4 sites in United States
- Volunteers
- 327 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea, Obesity (BMI>30)
Hypercapnic Burden in Adults With Obesity Undergoing Diagnostic Polysomnography for Suspected Obstructive Sleep Apnea
Obesity-related sleep hypoventilation represents a continuum ranging from isolated nocturnal hypoventilation to obesity hypoventilation syndrome.
- Conditions
- Obstructive Sleep Apnea, Obesity (BMI>30), Obesity Hypoventilation Syndrome (OHS), Sleep Hypoventilation
- Trial name
- HBO-POSA (NCT07809061)
- Testing
- Sleep Inertia Questionnaire (SIQ)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hospices Civils de Lyon
Insomnia, Depression
E-aid Sleep-focused TrEatment for Prevention of Major Depression (STEP-MD)
In the past, there were studies on relationship between insomnia and depression, and those studies found that depression can be the result of untreated insomnia.
- Conditions
- Insomnia, Depression, Self Harm
- Trial name
- NCT03309527
- Testing
- e-aid Cognitive Behavior Therapy, e-aid Sleep Hygiene Education
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Breast Cancer Female, Insomnia
Comparative Effectiveness Feasibility Trial for Insomnia Among Breast Cancer Survivors
Women with breast cancer who report insomnia that started or worsened during breast cancer diagnosis and treatment will be enrolled in a group behavioral trial to one of two arms testing cognitive behavioral therapy for insomnia…
- Trial name
- NCT03328169
- Testing
- Mindfulness-Based Therapy, Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- George Washington University
Excessive Daytime Sleepiness, Narcolepsy
A Study Of A Novel Compound For Excessive Daytime Sleepiness Associated With Narcolepsy
Histaminergic agents are known to be involved with the sleep/wake cycle. This compound is a histaminergic agent which therefore may improve alertness and awakeness in patients with excessive daytime sleepiness (EDS) associated…
- Trial name
- NCT01006122
- Testing
- PF-03654746
- Where
- 21 sites in United States
- Volunteers
- 95 people
- Sponsor
- Pfizer
Sleep Apnea, Obstructive
The Influence of the Sleep Apnea on the Neurological and Functional Recovery
The sleep respiratory troubles (central apnea or CHEYNES-Stokes dyspnea) are frequent after stroke. The association of the sleep respiratory troubles with a reserved functional prognosis is debated.
- Trial name
- SAS-AVC (NCT01321229)
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Refractory Hypertension
Study of the Relationships Between Refractory Hypertension, Overweight/Obesity and Sleep Apnea Syndrome
The purpose of the study is to investigate the links between blood pressure (BP), overweight or obesity, and sleep apnea syndrome (SAS), by studying a large cohort of subjects suffering from refractory hypertension.
- Trial name
- RHOOSAS (NCT00746902)
- Testing
- nCPAP
- Where
- France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Grenoble
Breast Neoplasm Female, Symptom Cluster
Somatic Acupressure for Symptom Cluster Management in Breast Cancer Survivors
This study is designed following the updated Medical Research Council (MRC) Framework for Developing and Evaluating Complex Interventions.
- Trial name
- NCT06412107
- Testing
- True acupressure, Usual care
- Where
- 2 sites in China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Charles Darwin University
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