Clinical trials: Sleep Disturbances and Insomnia
Sleep Quality
Effects of Biofeedback-based Music Program Using a Smart Device Application on Perioperative Sleep Quality
The purpose of this study is to investigate whether the effects of biofeedback-based music programs using a smart device application can improve perioperative sleep quality in patients undergoing breast cancer surgery.
- Trial name
- NCT05726162
- Testing
- biofeedback-based music program, Control
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Substance Abuse, Sleep Disturbances
Exploring Substance Use, Sleep Disturbances and Reward Sensitivity
According to foreign medical studies, substance use is closely related to reward sensitivity and sleep patterns. The purpose of this research is to understand the relationship between these three factors, which will help improve…
- Trial name
- NCT07028346
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Volunteers
- 154 people
- Sponsor
- Kwai Chung Hospital
Insomnia, Depression
Effects of Group Cognitive Behavioural Therapy on Comorbid Insomnia and Depression in Youth
Major depressive disorder (MDD) is among the most common psychiatric disorders among adolescents, and is associated with considerable psychosocial and functional impairments and an elevated risk of suicidal behaviour and…
- Trial name
- NCT03438331
- Testing
- Cognitive Behavioural Therapy for Insomnia (CBT-I), Cognitive Behavioural Therapy for Depression (CBT-D)
- Where
- Hong Kong
- Volunteers
- 133 people
- Sponsor
- The University of Hong Kong
Insomnia
Effects of Ramelteon on Driving Ability
The primary purpose of this study is to investigate the effects of bedtime administration of a single dose of ramelteon (8 mg), zopiclone (7.5 mg), and placebo on next-morning on-road driving performance.
- Trial name
- NCT00319215
- Testing
- Ramelteon 8 mg, Zopiclone 7.5 mg
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
CNS
2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly Subjects
This is a single-center, randomized, double-blind, placebo-controlled, sequential, multiple-dose study. The study will be conducted in two parts: Part A (6 cohorts of healthy adults receiving evening dosing) and Part B (one…
- Trial name
- NCT01673451
- Testing
- E2006
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Chronic Insomnia
FMT Capsules in Treatment of Patients With Insomnia Clinical Research
Objective: To investigate whether Fecal Microbiota Transplantation(FMT) can improve sleep in patients with insomnia, its effect on gut microbiota and its metabolites, and its effect on inflammatory factors, neurotransmitters and…
- Trial name
- NCT05427331
- Testing
- FMT capsule
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Third Military Medical University
Hepatic Encephalopathy, Covert Hepatic Encephalopathy
Affect of Melatonin on Sleep and Cognition in Cirrhosis
The goal of this clinical trial is to learn the affect of melatonin on sleep, cognitive function, and quality of life (QoL) in patients with cirrhosis and a complication called hepatic encephalopathy (HE).
- Conditions
- Hepatic Encephalopathy, Covert Hepatic Encephalopathy, Cirrhosis, Sleep Disturbances and Insomnia
- Trial name
- SNORE-HE (NCT07046429)
- Testing
- Melatonin tablet 3 mg once daily, Thiamine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Weill Medical College of Cornell University
Climacteric Syndrome
Efficiency of Placental Drug Melsmon® in Correction of Climacteric Symptoms in Premenopausal Women
The placental drug Melsmon® is effective for correction of insomnia and other climacteric symptoms in premenopausal women. Decrease of MMI is shown both in groups with Melsmon® and Placebo, but it was more significant in patients…
- Trial name
- NCT02749695
- Testing
- Melsmon
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Inna I. Kovalenko
Sleeping Disorders
Effects of Sesamin on Sleep Quality and Antioxidative Status
Sesame recognized as a common healthy food. Sesamin is extracted from sesame and has high antioxidant capacity which is commonly added in functional foods.
- Trial name
- NCT05678439
- Testing
- sesame extract
- Where
- 2 sites in Taiwan
- Volunteers
- 33 people
- Sponsor
- Taipei Medical University
Insomnia
Cognitive Behavioural Therapy for Insomnia for Chinese Adults: a RCT
Background: Insomnia is a common mental problem, where people experienced difficulty falling asleep, problem maintaining asleep and early morning awakening.
- Trial name
- CBTI (NCT04653155)
- Testing
- Cognitive behavioural therapy for insomnia
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- Hospital Authority, Hong Kong
Insomnia Disorder
Study to Assess the Long Term Safety and Tolerability of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep
Study to assess the long term safety and tolerability of daridorexant in adult and elderly subjects suffering from difficulties to sleep
- Trial name
- NCT03679884
- Testing
- Daridorexant 10 mg, Daridorexant 25 mg, Daridorexant 50 mg
- Where
- 106 sites in United States, Belgium and 12 more
- Volunteers
- 804 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Covid19, Neurocognitive Dysfunction
Long-term Neurocognitive and Psychiatric Consequences in Severe COVID-19 Survivors.
Long-term neurocognitive and psychiatric consequences of COVID-19 remain mostly unknown to date. It has been reported that coronaviruses cause direct central nervous system infection (Needham et al. 2020).
- Trial name
- NPQCOVID (NCT05019300)
- Testing
- Exposure: COVID-19 severity
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Exercise Recovery
Training Health Recovery and Improvement Via Levagen+® Evaluation
INTRODUCTION: Sports supplements and ergogenic aids are widely used for performance enhancement in recreational and professional sports.
- Trial name
- THRIVE (NCT07359534)
- Testing
- Levagen+® Palmitoylethanolamide (PEA)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Westminster
Insomnia, Hepatic Impairment
Pharmacokinetics and Safety Study of YZJ-1139 in Subjects With Mild, Moderate and Normal Hepatic Impairment
Primary Objectives: To evaluate the effect of the subjects with mild (Child Pugh A), moderate (Child Pugh B) and normal hepatic impairment on the pharmacokinetics of YZJ-1139 Secondary Objectives: To evaluate the safety of a…
- Trial name
- NCT06671509
- Testing
- YZJ-1139
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Shanghai Haiyan Pharmaceutical Technology Co., Ltd.
Alzheimer's Disease
The Effect of rTMS Treatment on Alzheimer's and Sleep Quality
This research is being conducted to study whether rTMS (repetitive Transcranial Magnetic Stimulation) could be potentially used as a treatment for Alzheimer's disease.
- Trial name
- rTMS (NCT01894620)
- Where
- 2 sites in Canada
- Volunteers
- 11 people
- Sponsor
- Dr. Zahra Kazem-Moussavi
Sleep Quality
Sleep Quality Among HCWs
The novel coronavirus has brought the world into uncharted waters. Whole countries are on lockdown, the economy has ground to a halt, and many people are afraid for themselves and their loved ones.
- Trial name
- NCT04549350
- Testing
- PSQI
- Where
- Egypt
- Volunteers
- 217 people
- Sponsor
- Zagazig University
Chronic Renal Failure, Sleep Disorder
Light Therapy on Sleep Quality in Dialysis Patients
Sleep disorders are common in dialysis patients. At present, the management of insomnia in patients with chronic renal failure is not significantly different from that of the general population, which focuses on the management of…
- Conditions
- Chronic Renal Failure, Sleep Disorder, Hemodialysis, Light Therapy
- Trial name
- LUMIDIAL (NCT04089397)
- Testing
- Light Therapy
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Cancer, Insomnia
A Comparison of MBSR and CBT for the Treatment of Insomnia in Cancer
Sleep disturbance in cancer patients is often overlooked despite its documented high prevalence and negative impact. There are few empirically validated non-pharmacological treatments for insomnia and many patients are unwilling…
- Trial name
- I-CAN SLEEP (NCT01335776)
- Testing
- Mindfulness-Based Stress Reduction, Cognitive Behavior Therapy
- Where
- Canada
- Volunteers
- 111 people
- Sponsor
- University of Calgary
Insomnia, Alcohol Use Disorder
CBT-I on Alcohol Treatment Outcomes Among Veterans
Project SAVE aims to examine the feasibility, acceptability, and initial efficacy of a CBT-I supplement to alcohol treatment of Veterans.
- Trial name
- Project SAVE (NCT03806491)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene, Alcohol Use Disorder Treatment as Usual
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Insomnia
The Effects of Lactobacillus Plantarum PS128 in Self-Reported Insomniacs
To determine whether PS128 (1) reduces the severity of anxiety and depressive symptoms, (2) adjusts autonomic nervous system functioning, and (3) improves sleep quality.
- Trial name
- NCT04592276
- Testing
- PS128
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Yang Ming Chiao Tung University
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