Clinical trials: Sleep Disturbances and Insomnia
Physical Inactivity
The Effect of Brain Breaks on People With Mental Health Problems
Regular physical activity (PA) and adopting an active lifestyle protect against non-communicable diseases such as diabetes, cardiovascular diseases, hypertension, obesity, and colon cancer in the general population.
- Trial name
- NCT05783674
- Testing
- Brain Breaks® Video Exercises, Posture training
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Istinye University
Insomnia
Effects of Ramelteon on Driving Ability
The primary purpose of this study is to investigate the effects of bedtime administration of a single dose of ramelteon (8 mg), zopiclone (7.5 mg), and placebo on next-morning on-road driving performance.
- Trial name
- NCT00319215
- Testing
- Ramelteon 8 mg, Zopiclone 7.5 mg
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Lymphedema
Effects of Inspiratory Muscle Training on Lymphedema
The aim of this study is to examine the effect of inspiratory muscle training on lymphedema volume, subcutaneous tissue thickness, upper extremity functionality and sleep quality in the treatment of upper extremity lymphedema.
- Trial name
- NCT06521268
- Testing
- Inspiratory muscle training, Decongestive treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Biruni University
Dysbiosis, Cardiometabolic Health Indicators
Almonds, Gut Microbiome and Kids
This 8-week parallel-arm randomized controlled trial (N=70; ages 6-13) will determine the impact of daily almond butter consumption on gut microbiome composition and function, intestinal barrier integrity, and cardiometabolic…
- Trial name
- NCT07636850
- Testing
- Creamy Richards 100% Almonds! Creamy Natural Almond Butter, Cadbury Milk Chocolate Spread
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Florida State University
Restless Leg Syndrome (RLS)
Combined Effects of Near-Infrared Light and Vibration on Diabetic Patients With Restless Leg Syndrome
This Randomized Clinical Trial, titled "Combined Effects of Near-Infrared Light and Vibration on Pain, Sleep Quality and Symptom Severity in Diabetic Patients with Restless Leg Syndrome," aims to evaluate a non-pharmacological…
- Trial name
- NCT07308080
- Testing
- Near-Infrared Light Therapy, Vibration, Conventional Physical Therapy
- Volunteers
- 42 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Insomnia Disorder, Cognitive Functioning
Assessing Modified CBTi in Adults With Insomnia Disorder
Cognitive Behavioral Therapy for Insomnia (CBTi) is the gold-standard, first line recommended treatment for insomnia, and has considerably better long-term outcomes than medications.
- Trial name
- NCT06600516
- Testing
- CBTi: Stimulus Control Core, CBTi: Sleep Restriction Core, CBTi: Sleep Compression Core
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Idaho State University
Depression, Sleep Quality
Sleep to Activate Mood Promotion
The investigators are aiming to examine the acceptability and feasibility of a portable bright light therapy instrument to improve sleep disturbance in a preventive intervention for depression.
- Trial name
- STAMP (NCT02413294)
- Testing
- Re-Timer glasses
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Insomnia
Video-Based Cognitive Behavioral Therapy for Insomnia in Adults Cancer Patients and Survivors
SLEEP-4-ALL-1 is a pilot and ecological study corresponding to the developpement phase of a randomized controlled multicentric trial SLEEP-4-ALL-2.
- Trial name
- SLEEP-4-ALL (NCT03981666)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 177 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Primary Insomnia
Sleep Laboratory Study of MK0928 in Adult Patients With Primary Insomnia (0928-041)(TERMINATED)
A study to evaluate the efficacy, safety and tolerability of MK-0928 in Primary Insomnia.
- Trial name
- NCT00266357
- Testing
- MK0928, gaboxadol / Duration of Treatment: 6 days for treatment periods (2 days/dose)
- Volunteers
- 50 people
- Sponsor
- H. Lundbeck A/S
Advanced Cancer, Anorexia
Effects of Mirtazapine on Appetite in Advanced Cancer Patients
Primary objective: This is a preliminary study to determine if Mirtazapine in comparison to placebo will improve appetite in advanced cancer patients with anorexia and weight loss.
- Conditions
- Advanced Cancer, Anorexia, Weight Loss, Insomnia
- Trial name
- NCT00488072
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- M.D. Anderson Cancer Center
Dementia, Alzheimer Disease
The Healthy Patterns Sleep Study
The Healthy Patterns Study intervention is a home-based activity intervention designed to improve symptoms of circadian rhythm disorders (CRD) and quality of life (QOL) in home-dwelling persons with dementia.
- Conditions
- Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder
- Trial name
- NCT03682185
- Testing
- Attention-Control Condition, Timed Activity Intervention
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Insomnia
Study to Investigate the Effects of Melatonin, Temazepam & Zolpidem on Sleep EEG in Men and Women
This study has been designed to compare the effects of melatonin with those of drugs (temazepam and zolpidem) regularly prescribed for the treatment of insomnia, in healthy, middle-aged volunteers.
- Trial name
- NCT00940550
- Testing
- Prolonged-release melatonin, Temazepam, Zolpidem
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Insomnia, Psychosis
CBT-I for Psychosis: Guidelines, Preliminary Efficacy, and Functional Outcomes
The goal of this project is to develop guidelines for the clinical tailoring of Cognitive Behavioral Therapy for Insomnia (CBT-I) for Veterans with psychotic disorders and insomnia, and to test the acceptability, feasibility, and…
- Trial name
- CBT-I (NCT02535923)
- Testing
- Cognitive Behavioral Therapy-Insomnia, Health and Wellness
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- VA Office of Research and Development
Hepatitis B
The Effect of Hot Foot Bath on Sleep Quality and Fatigue
This study will be conducted to investigate the effects of hot foot baths on patients' sleep quality and fatigue severity levels.The study will be conducted in the Gastroenterology clinic of a university hospital in Türkiye.
- Trial name
- NCT06864923
- Testing
- Hot foot bath application group
- Volunteers
- 60 people
- Sponsor
- Uludag University
Insomnia, Depression
Cognitive-Behavioral Therapy for Sleep Disturbance in Patients Undergoing Hemodialysis
Background More than 50% of dialysis patients experience sleep disturbances that significantly affect quality of life, overall morbidity, and mortality.
- Conditions
- Insomnia, Depression, Inflammation
- Trial name
- NCT01159197
- Testing
- cognitive behavioral therapy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Far Eastern Memorial Hospital
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Mild Cognitive Impairment, Cognitive Function
Binaural Beats for Cognitive Function in Older Adults With Mild Cognitive Impairment in Nursing Homes
This study will evaluate whether binaural beats can improve cognitive function in older adults with mild cognitive impairment living in nursing homes.
- Trial name
- BB-MCI (NCT07735910)
- Testing
- Binaural Beats Embedded in Old Songs, Old Songs
- Where
- 3 sites in China
- Volunteers
- 60 people
- Sponsor
- China Medical University, China
Chronic Insomnia
The Study of Combination Use of Melatonin Receptor Agonist for Dose Reduction or Interruptions of Benzodiazepine (BZD) and Non-BZD Hypnotics on Chronic Insomnia
To investigate effects on combination use of Ramelteon in the dose reduction or interruption process of (non-)BZD hypnotics during the dose reduction or interruption algorithm.
- Trial name
- BRED (NCT03461042)
- Testing
- Ramelteon 8mg
- Where
- Japan
- Volunteers
- 17 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Attachment, Mother-Infant Interaction
The Effect of Affirmation and Massage on Babies
The research was designed as a randomized controlled trial model to examine the effects of affirmation and infant massage taught to the parents of 0-6 month-old infants registered in a Family Health Center and a Private Medical…
- Conditions
- Attachment, Mother-Infant Interaction, Sleep Quality
- Trial name
- NCT05489861
- Testing
- M-AM, F-AM
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
PTSD - Post Traumatic Stress Disorder, Insomnia
Suvorexant 3 - PE-PC
The goal of this clinical trial is to learn if combining suvorexant (a sleep medication) with a shorter form of prolonged exposure therapy called PE-PC works to treat PTSD symptoms and improve sleep in Veterans and military…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Insomnia, TBI (Traumatic Brain Injury)
- Trial name
- NCT07686731
- Testing
- Suvorexant, Prolonged Exposure Therapy for Primary Care (PE-PC)
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Northern California Institute of Research and Education
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