Clinical trials: Sleep Disturbances and Insomnia
Insomnia, Pain
Treatment of Insomnia Secondary to Chronic Pain
Several studies have shown that behavioral therapy for chronic pain can be beneficial for chronic pain and that behavioral therapy for insomnia can be beneficial for insomnia.
- Trial name
- NCT00127790
- Testing
- CBT for Insomnia (CBT-I), CBT for Pain (CBT-P)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Rochester
Insomnia Due to Mental Disorder
Evaluation of the ChronoS Therapy on the Severity of Sleep Disturbances Among Patients With Mood Disorders: A Within-subjects Study
A new psychotherapy has been developed within the Psychiatry, Sleep and Chronobiology Reference Center (ChronoS) since January 2022.Results have shown relevant clinical interest on insomnia symptoms, as well on mood, anxiety and…
- Trial name
- CRHONOS (NCT07180290)
- Testing
- Psychotherapy
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Centre Hospitalier St Anne
Neck Pain Chronic, Insomnia Chronic
Effect of Acupuncture on Chronic Nonspecific Neck Pain and Insomnia
The study aims to assess the efficacy and safety of acupuncture among patients with chronic nonspecific neck pain and insomnia, compared with sham acupuncture.
- Trial name
- NCT06996210
- Testing
- Acupuncture
- Volunteers
- 124 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Insomnia
Internet-Based Cognitive-Behavioral Therapy for Insomnia
The aim of this study is to develop an Internet-based self-help therapy program for insomnia in Chinese language, and to conduct a randomized waiting-list controlled trial on the efficacy of Internet-based self-help therapy for…
- Trial name
- NCT01719120
- Testing
- Cognitive-Behavioral Therapy
- Where
- Hong Kong
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Chronic Pain, Anxiety
Nu-V3 Non-Invasive Nerve Stimulation Device Trial for Chronic Pain, Anxiety, Depression, Sleeplessness
The Nu-V3 Clinical Study is a prospective, single-arm, open-label, multi-center study using the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3 (NCT05335980)
- Testing
- Nu-V3
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Nu-Life Solutions
Healthy Individuals
Impact Of Aerobic Exercise on Sleep Quality and Postural Control Interplay Among University Students
The purpose of this study is to investigate the impact of moderate-intensity aerobic treadmill exercise on sleep quality and postural control interplay among university students with poor sleep quality.
- Trial name
- NCT07909980
- Testing
- Aerobic exercise Training, Sleep hygiene education
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Insomnia, Alzheimers Disease Related Dementias
Enhanced CBTi for Older Adult Sleep and Cognition
This randomized clinical trial on 60+ aged and independent-living healthy individuals with symptoms of insomnia will attempt to improve sleep and health outcomes related to sleep with enhancement of a clinical intervention…
- Trial name
- R44 (NCT05015803)
- Testing
- CBTi with Application, CBTi, Sleep Hygiene Education
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Penn State University
Sleep Initiation and Maintenance Disorders
Traditional Chinese Medicine Herbal Sachet for Insomnia in Older Adults
The goal of this clinical trial was to determine whether nightly exposure to a Traditional Chinese Medicine herbal sachet could reduce insomnia symptoms and improve sleep quality in adults aged 60 years or older.
- Trial name
- NCT07788547
- Testing
- Traditional Chinese Medicine Herbal Sachet
- Where
- China
- Volunteers
- 154 people
- Sponsor
- Macao Polytechnic University
Insomnia
Study to Compare the Awakening Threshold Effects of Belsomra 10 mg and 20 mg to Placebo in Non-elderly Insomniacs
Phase IV 3-Way Double-blind, Randomized, Crossover Study to Compare the Awakening Threshold Effects (responsivity) of Belsomra 10 mg and 20 mg to Placebo in non-elderly Insomniacs
- Trial name
- NCT03312517
- Testing
- Suvorexant 10 mg, Suvorexant 20 mg
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Henry Ford Health System
Insomnia
Effects of Resistance Physical Exercise in Patients With Chronic Primary Insomnia
INTRODUCTION: The primary insomnia, according to the concepts of the DSM IV, is a disorder characterized by difficulty initiating or maintaining sleep, waking early or by non-restorative sleep, resulting in losses in the daily…
- Trial name
- IER (NCT01571115)
- Testing
- Physical Exercise
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Chronic Insomnia
Transcranial Temporal Interference Stimulation (tTIS) for Chronic Insomnia
The purpose of this exploratory randomized controlled clinical trial is to evaluate the efficacy and safety of transcranial temporal interference stimulation (tTIS) in the treatment of chronic insomnia.
- Trial name
- NCT07755852
- Testing
- Active Transcranial Temporal Interference Stimulation (tTIS)-Experimental
- Volunteers
- 30 people
- Sponsor
- Ruijin Hospital
Old Age, Knee Replacement Surgery
Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality
Sleep disturbances are prevalent in older patients with osteoarthrosis or fracture who are scheduled for knee or hip replacement surgery.
- Conditions
- Old Age, Knee Replacement Surgery, Hip Replacement Surgery, Dexmedetomidine
- Trial name
- NCT05950646
- Testing
- Dexmedetomidine, Esketamine, Normal saline
- Where
- 2 sites in China
- Volunteers
- 154 people
- Sponsor
- Peking University First Hospital
Occupational Stress, Sleep Quality
Curcumin Nano Patch and Autonomic Function in Shift-Working Healthcare Professionals
This randomized, open-label, placebo-controlled crossover study compares a curcumin-containing patch with a cooling placebo patch without curcumin in healthcare professionals who work rotating shifts.
- Trial name
- NCT07910279
- Testing
- Curcumin Nano Patch
- Where
- Taiwan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Insomnia, Sleep
Vestibular Nerve Stimulation to Improve Sleep
A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS) compared to a sham control a as a means of improving sleep as measured by ISI scores and EEG recordings The…
- Conditions
- Insomnia, Sleep, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT04219566
- Testing
- VeNS
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Obstructive Sleep Apnea (OSA), Snoring
The Impact of Technology in Obstructive Sleep Apnea Myofunctional Therapy
This is a study to test if performing airway exercises to improve snoring and sleep apnea using a mobile phone app is better than using a hardcopy guide.
- Conditions
- Obstructive Sleep Apnea (OSA), Snoring, Sleep Quality
- Trial name
- OSA (NCT06905951)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Case Western Reserve University
Sleep Initiation and Maintenance Disorders, Mental Disorders
A 6-Month Efficacy and Safety Study of Org 50081 in Adult Patients With Chronic Primary Insomnia (21106/P05701/MK-8265-002)
To investigate the long-term efficacy and safety of treatment with esmirtazapine (Org 50081, SCH 900265, MK-8265) compared to placebo, in participants with chronic primary insomnia.
- Conditions
- Sleep Initiation and Maintenance Disorders, Mental Disorders, Dyssomnias, Sleep Disorders
- Trial name
- NCT00631657
- Testing
- Esmirtazapine
- Volunteers
- 460 people
- Sponsor
- Merck Sharp & Dohme LLC
Rotator Cuff Injuries, Postoperative Pain
Effect of a Posterior Shoulder Pillow on Pain and Sleep Quality After Rotator Cuff Repair
The goal of this clinical study is to learn if using a special pillow placed behind the shoulder can help to reduce pain and improve sleep for patients after surgery to repair a torn rotator cuff.
- Conditions
- Rotator Cuff Injuries, Postoperative Pain, Sleep Quality
- Trial name
- NCT07372222
- Testing
- Posterior Shoulder Pillow, Conventional Rehabilitation Protocol
- Volunteers
- 126 people
- Sponsor
- Peking University Third Hospital
Asthma, Insomnia Chronic
Feasibility and Acceptability of an Internet-based Cognitive-behavioral Treatment for Insomnia in Adults With Asthma
The purpose of the proposed study are to explore changes in sleep and asthma outcomes from baseline to post-treatment in adults with asthma and comorbid insomnia who underwent Internet-based cognitive-behavioral treatment for…
- Trial name
- NCT03002402
- Testing
- Internet-based CBT-I
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Pittsburgh
Pregnancy Related, Depression
Effects of Digitally Delivered and Group-based CBT-I in Pregnant Women With Comorbid Insomnia and Depression
Major depressive disorder (MDD) is a debilitating and recurrent illness associated with a constellation of grave consequences and is among the most common psychiatric disorders during the pregnancy and postpartum periods.
- Conditions
- Pregnancy Related, Depression, Insomnia
- Trial name
- NCT06054256
- Testing
- Group CBT-I, App-based CBT-I, Health related psychoeducation
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- The University of Hong Kong
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