Clinical trials: Sleep Disturbances and Insomnia
Insomnia, Adults
A Theory-based Sleep Hygiene Education for Insomnia Patients
Insomnia is a prevalent sleep disorder associated with substantial negative health consequences, including fatigue, irritability, and impaired daytime functioning.
- Trial name
- NCT07559305
- Testing
- Sleep Hygiene Education
- Where
- Hong Kong
- Volunteers
- 11 people
- Sponsor
- The Hong Kong Polytechnic University
Insomnia
Efficacy and Safety of the Herbal Medicine Sominex ® (Passiflora Incarnata L., Valeriana Officinalis L. and Crataegus Oxyacantha L.), Manufactured by the Laboratory EMS S / A in Patients With Psychophysiological Insomnia
The main objective of this study is to evaluate the clinical efficacy of the drug Sominex (Valeriana officinalis L., 40 mg, 30 mg Crataegus oxyacantha L. and Passiflora incarnata L.
- Trial name
- NCT01100645
- Testing
- Sominex
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Azidus Brasil
Insomnia
Sounds for Sleep Study in Patients Suffering From Moderate to Severe Insomnia
Assess the effect of a customized audio track delivered via standard commercially-available bone conduction headsets on the quality of sleep
- Trial name
- NCT06021795
- Testing
- Sound Treatment
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Third Wave Therapeutics
Mental Health Issue, Physical Inactivity
Effect of Chen Taichi on College Students' Physical and Psychological Health.
Tai Chi is a kind of traditional martial arts in China, which has a remarkable function in healthcare. It has been used in many diseases as a complementary theory.
- Trial name
- NCT05379075
- Testing
- 26 styles of Chen Taichi training based on Relaxation guidelines, 26 styles of Chen Taichi training based on Coordination guidelines
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Insomnia
Fifty Two Week Extension Trial of Org 50081 (Esmirtazapine) in the Treatment of Insomnia (P05708)
This trial is a 52-week, open-label extension trial to investigate safety and to explore efficacy of Org 50081 (Esmirtazapine) in participants who completed Protocol 176001 (P05706) (NCT00482612) or 176002 (P05707) (NCT00506389).
- Trial name
- NCT00610675
- Testing
- Org 50081
- Volunteers
- 346 people
- Sponsor
- Merck Sharp & Dohme LLC
Arthritis, Rheumatoid
Effectiveness and Safety of Physical Exercises in the Improvement of the Sleep Quality. Regarding Rheumatoid Arthritis
Physical exercise programs are effective and safe for the improvement of the sleep efficiency in patients with Rheumatoid Arthritis.
- Trial name
- SRA (NCT01919645)
- Testing
- Combined Training ( Strength + Aerobics)
- Where
- Brazil
- Volunteers
- 43 people
- Sponsor
- Federal University of São Paulo
Tinnitus
FR-taVNS Tinnitus Tria
Tinnitus is a common neurosensory symptom affecting 12-30% of adults and is closely associated with anxiety, sleep disturbance, and autonomic dysregulation.
- Trial name
- NCT07711639
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Cancer, Insomnia Chronic
Device Feasibility and Acceptability to Improve Insomnia in Cancer
Sleep disruption is common among young adult cancer survivors for a variety of reasons. Cognitive behavioral therapy for insomnia (CBT-I) has been shown to improve chronic sleep disorders.
- Trial name
- NCT05875129
- Testing
- VAVA prototype
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medstar Health Research Institute
Rheumatic Diseases
A Study on Health - Related Quality of Life in Patients With Rheumatic Diseases Taking Tramadol 37.5mg/Acetaminophen 325mg Tablets
The objective of this observational study is to assess improvement of quality of life in the patients who are administered Tramadol 37.5mg/Acetaminophen 325mg tablets for 10~14 weeks according to the investigator's discretion in…
- Trial name
- NCT00642837
- Testing
- Tramadol/acetaminophen
- Volunteers
- 982 people
- Sponsor
- Janssen Korea, Ltd., Korea
Chronic Pelvic Pain Syndrome (CPPS)
Kinesiophobia, Physical Activity, Sleep, and Quality of Life in Women With Chronic Pelvic Pain
The study will include women who present to the Obstetrics and Gynecology outpatient clinic of Kırşehir Ahi Evran Training and Research Hospital with complaints of pelvic pain and are diagnosed with PCAS after a detailed…
- Trial name
- NCT07833280
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ahi Evran University Education and Research Hospital
Advanced Malignant Solid Neoplasm, Delirium
Suvorexant for Insomnia to Prevent Delirium in Hospitalized Cancer Patients
This phase IV trial compares suvorexant with standard of care to standard of care alone for improving difficulty sleeping (insomnia) and reducing confusion (delirium) in hospitalized cancer patients.
- Conditions
- Advanced Malignant Solid Neoplasm, Delirium, Hematopoietic and Lymphatic System Neoplasm, Insomnia
- Trial name
- NCT06834386
- Testing
- Best Practice, Electronic Health Record Review, Interview
- Where
- United States
- Sponsor
- Mayo Clinic
Sleep Initiation and Maintenance Disorders, Depression
Improving Sleep and Psychological Functioning in People With Depression and Insomnia
This study will evaluate the safety and effectiveness of treatment with both a sleeping pill and antidepressant medication in improving sleep and psychological functioning in people with depression and insomnia.
- Trial name
- NCT00247624
- Testing
- Eszopiclone, Fluoxetine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Wake Forest University Health Sciences
Insomnia
Driving Performance After Middle of the Night Administration of 3.5 mg Zolpidem Tartrate Sublingual Tablet
A study in healthy volunteers of the next morning driving performance after middle-of-the-night dosing of 3.5 mg zolpidem tartrate sublingual tablet, a sleep aid.
- Trial name
- NCT01106859
- Testing
- zopiclone, zolpidem tartrate sublingual tablet
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Transcept Pharmaceuticals
Insomnia, Sleep Initiation and Maintenance Disorders
Zolpidem (Myslee) Post Marketing Study in Adolescent Patients With Insomnia - Evaluation With Polysomnography
To evaluate the efficacy of zolpidem for adolescent insomniacs with polysomnography
- Trial name
- NCT00653562
- Testing
- zolpidem
- Where
- 4 sites in Japan
- Volunteers
- 11 people
- Sponsor
- Astellas Pharma Inc
Chronic Obstructive Pulmonary Disease
Effects of Temazepam in Patients With Chronic Pulmonary Obstructive Disease
The purpose of this study is to evaluate the effects of temazepam during sleep and in daytime on dyspnea, gas exchange and sleep quality in patients with chronic obstructive pulmonary disease.
- Trial name
- NCT00245661
- Testing
- Temazepam
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Rijnstate Hospital
Depression, Insomnia
Cognitive Behavioral Therapy for Insomnia with RTMS
Depression and insomnia occur together in a substantial number of patients. Transcranial magnetic stimulation (TMS) is an effective treatment for depression, but does not help insomnia symptoms in depressed patients.
- Trial name
- NCT04258618
- Testing
- CBT-I (Cognitive Behavioral Therapy for Insomnia) with rTMS, Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Medical University of South Carolina
Major Depressive Disorder (MDD) With Insomnia
Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia
Major Depressive Disorder (MDD) affects 5% of the global population and is the second leading cause of disability worldwide. Despite the widespread use of antidepressants, 50-60% of patients do not respond adequately after 8…
- Trial name
- CombiChronoS (NCT07120880)
- Testing
- AD + SHR + active LT and extended-release melatonin 2mg
- Where
- France
- Volunteers
- 184 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Alzheimer Disease, Dementia
Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals With Alzheimer's Disease
This study seeks to evaluate the utility and efficacy of the Non-Contact Sleep Quality Monitor System when used to monitor the sleep quality of individuals living in long-term care (LTC) with either Alzheimer's Disease (AD) or…
- Conditions
- Alzheimer Disease, Dementia, Sleep Disturbance
- Trial name
- NCT06045988
- Testing
- Non-Contact Sleep Quality Monitor System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Insomnia
Study on the Efficacy and Safety of Anesthesia-Induced Sleep Therapy for Refractory Insomnia
The incidence of refractory insomnia is rising annually, with traditional therapies offering limited efficacy. Anesthesia-Induced Sleep (AIS), involving anesthetic infusion like dexmedetomidine, is emerging.
- Trial name
- NCT07255027
- Testing
- Dexmedetomidine and conventional oral drug, Conventional oral drug therapy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Insomnia, Metacognitive Beliefs
Insomnia After the COVID-19 Pandemic
The aim of this study is to investigate the levels of insomnia 3 months after (T2) the strict physical distancing government initiated physical distancing protocols related to the COVID-19 pandemic (T1).
- Conditions
- Insomnia, Metacognitive Beliefs, Anxiety, Depression
- Trial name
- NCT04443361
- Volunteers
- 5,000 people
- Sponsor
- University of Oslo
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