Clinical trials: Sleep Disturbances and Insomnia
Depressive Symptoms Mild to Moderate in Severity, Anxiety
Effects of Intranasal Ketamine on Depression and Anxiety in Palliative Care Cancer Patients
With progression of cancer, patients and their caregivers experience challenging emotional distress, which can make them feel depressed and very anxious. Patients with advanced cancer often do not have long to live.
- Conditions
- Depressive Symptoms Mild to Moderate in Severity, Anxiety, Quality of Life (QOL), Caregiver Burden
- Trial name
- Keta-Care (NCT06665568)
- Testing
- Intranasal ketamine hydrochloride
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
COPD, Sleep Quality of ICU Patients
Virtual Reality in ICU Patients With COPD
This study aims to evaluate the effect of a virtual reality glasses application on sleep quality, anxiety, and vital signs in patients with chronic obstructive pulmonary disease hospitalized in the intensive care unit.
- Conditions
- COPD, Sleep Quality of ICU Patients, Anxiety
- Trial name
- VR-ICU-COPD (NCT07475650)
- Testing
- virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Aging, Age Problem
Technologies for Participatory Medicine and Health Promotion in the Elderly Population
Introduction: The progressive aging of the population is a socio-demographic phenomenon experienced by most countries in the world in recent decades, especially in Japan and in many European Union countries.
- Trial name
- GERIATIC (NCT03504813)
- Testing
- Physical activities program, Relaxation training, Training of the pelvic floor
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- Universidade da Coruña
Physical Activity, Sleep Apnea
Examining the Association Between Physical Activity and Sleep Quality in Children With Autism Spectrum Disorder
This study aims to investigate whether physical activity intervention would be effective to improve sleep quality in children with ASD, and investigate how physical activity impacts on sleep in children with ASD through…
- Conditions
- Physical Activity, Sleep Apnea, Autism Spectrum Disorder
- Trial name
- NCT03348982
- Testing
- Jogging program
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
COVID-19, Long COVID
Effectiveness of Transcranial Direct Current in Patients With Persistent COVID-19 With Headaches and Chronic Pain.
This study aims to verify the efficacy/effectiveness of treatment with transcranial direct current stimulation (TDCS) in patients with Long Covid who experience headaches, migraines, and chronic pain, such as arthralgia and…
- Conditions
- COVID-19, Long COVID, Long Covid19, SARS CoV 2 Infection
- Trial name
- NCT05780450
- Testing
- Transcranial Direct Current Therapy (tDCS)
- Where
- 2 sites in Spain
- Volunteers
- 87 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Fibromyalgia
The Effect of Digital Cognitive Behavioural Therapy for Insomnia on Physical Activity in Fibromyalgia
The goal of this clinical trial is to learn if a digital sleep therapy program (digital Cognitive Behavioural Therapy for Insomnia or dCBT-I) works to improve quality of life and movement in adults with fibromyalgia who also have…
- Trial name
- PainLESS-2 (NCT07465991)
- Testing
- Digital Cognitive Behavioural Therapy for Insomnia, Sleep Hygiene Education Materials
- Where
- 2 sites in United Kingdom
- Volunteers
- 142 people
- Sponsor
- University of Oxford
Sleep Quality, Psychological Health
Efficacy of Parent-child Sleep Intervention
Background: Parents of healthy neonates commonly face sleep disruptions and disturbances after delivery. Notably, increasing challenges are evident among parents of ill infants who required clinical care after birth .
- Conditions
- Sleep Quality, Psychological Health, Infant Health
- Trial name
- NCT06143917
- Testing
- parent-child sleep intervention
- Where
- Taiwan
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Caregivers
Mobile Technology and Data Analytics to Identify Real-time Predictors of Caregiver Well-Being
The purpose of this study is to test whether personalized messages from an easy-to-use mobile app improve mood and stress among care partners and to see if care partners like using the app.
- Trial name
- NCT04556591
- Testing
- Just-in-time adaptive intervention (JITAI), Control
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Insomnia Chronic
Mindfulness Meditation and Insomnia in Alzheimer Disease Caregivers
Treatment of insomnia in caregivers is needed given that 60% of Alzheimer disease caregivers report sleep complaints, and insomnia may add to the burden of AD caregiving and contribute to morbidity and mortality risk.
- Trial name
- CARES (NCT03538574)
- Testing
- CBT-I, MAP-I
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- University of California, Los Angeles
Burn Injury
Effects of Non-Invasive Vagus Nerve Stimulation in Adolescent Burn Patients
This study will evaluate the effects of non-invasive vagus nerve stimulation in adolescents aged 12 to 18 years who have burn injuries.
- Trial name
- NCT07566923
- Testing
- Non-Invasive Vagus Nerve Stimulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Fenerbahce University
Anxiety
Effects of Tai Chi Chuan on Psychobiological Indicators of Anxiety and Sleep Quality in Young Adults
The purpose of this study is to determine the feasibility of a 10-week tai chi chuan intervention as a treatment for anxiety and sleep quality in young adults.
- Trial name
- NCT01624168
- Testing
- Anxiety Management Education, 10 week tai chi intervention, Enhanced tai chi instruction
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Intertrochanteric Fractures, Hip Fractures
Liposomal Bupivacaine Fascia Iliaca Block for Perioperative Sleep Quality in Elderly Patients With Intertrochanteric Fracture
Older adults with hip fracture often experience severe pain before and after surgery. This pain can cause anxiety and poor sleep, and may increase the risk of postoperative delirium (sudden confusion after surgery).
- Conditions
- Intertrochanteric Fractures, Hip Fractures, Sleep Disturbance, Postoperative Delirium
- Trial name
- NCT07892859
- Testing
- Liposomal Bupivicaine, Saline Solution (NaCl 0,9%)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Li Xiaoyuan
Coronary Artery Disease, Sleep Disorder; Breathing-Related
Comorbid Insomnia and Sleep Disordered Breathing in Patients Undergoing Cardiac Rehabilitation
The purpose of this research is to determine how frequently sleep disorders such as sleep disordered breathing and insomnia occur in patients with coronary artery disease enrolled in cardiac rehabilitation.
- Conditions
- Coronary Artery Disease, Sleep Disorder; Breathing-Related, Sleep Disorder; Insomnia Type
- Trial name
- NCT04992676
- Testing
- Polysomnograpy, actigraphy
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Mayo Clinic
Insomnia
Transcranial Magnetic Stimulation for Treatment of Insomnia
Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique that has been approved as a treatment of depression in patients that have not responded to a trial of one antidepressant medication.
- Trial name
- TMSI (NCT02196025)
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Florida
Obesity Hypoventilation Syndrome (OHS), Hypoventilation
Effects of Exercise Training on Exercise Capacity and Sleep Quality in Patients With Obesity Hypoventilation Syndrome
Obesity Hypoventilation Syndrome is defined as a combination of obesity (BMI ≥ 30 kg/m2) and daytime hypercapnia in arterial blood gas analysis (PaCO2 > 45 mmHg) without other pathologies that cause hypoventilation.
- Conditions
- Obesity Hypoventilation Syndrome (OHS), Hypoventilation, Obesity, Respiration Disorders
- Trial name
- NCT05398068
- Testing
- Exercises and Diet, Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Insomnia
Online or Face-to-face Treatment for Insomnia?
The object of this study is to compare internet-delivered treatment for insomnia to face-to-face treatment and a waiting-list. In this study participants are randomized to: 1) online cognitive-behavioral intervention; 2)…
- Trial name
- NCT01955850
- Testing
- Cognitive behavioral treatment for insomnia
- Where
- Netherlands
- Volunteers
- 90 people
- Sponsor
- VU University of Amsterdam
Creutzfeldt-Jakob Syndrome
The Role of the Coagulation Pathway at the Synapse in Prion Diseases
The study hypothesis is that that the deleterious effect of prions on the brain may be mediated (at least partially) by activation of serine proteases involved in the coagulation system.
- Trial name
- NCT02480725
- Testing
- collect CSF (Cerebrospinal fluid) sample
- Volunteers
- 50 people
- Sponsor
- Sheba Medical Center
Insomnia
Group Cognitive Behavioral Therapy (CBT I) Vs. Quetiapine for Residual Insomnia Impairing Recovery Among Elderly With Stable Major Affective Disorders
The purpose of this pilot study is to assess feasibility and patient accessibility in order to design an adequately powered study to compare group cognitive behavioral therapy for insomnia (CBT-I) to quetiapine in non-demented…
- Trial name
- NCT00462618
- Testing
- Quetiapine, Cogntive behavioral therapy
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Insomnia
The Complementary Effect of Ear Acupressure on Older Patients With Chronic Insomnia
Ear acupressure is commonly applied to treat insomnia in Oriental clinical practice but lacking the evidence of the randomized controlled trial (RCT)of ear acupressure on insomnia.
- Trial name
- NCT00832468
- Testing
- ear acupressure
- Where
- Taiwan
- Volunteers
- 72 people
- Sponsor
- National Yang Ming Chiao Tung University
Insomnia Chronic, Pain, Chronic
Sleep Intervention for Chronic Insomnia Using Virtual Reality Pilot Study
Sleep disturbances are common among chronic pain patients, with reports typically ranging from 50-70% of patients reporting sleep difficulties.
- Trial name
- iVR (NCT04253691)
- Testing
- Virtual Reality Mediated Relaxation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Missouri-Columbia
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