Clinical trials: Sleep Hypopnea
Sleep Apnea, Obstructive, Type 1 Diabetes (T1D)
Type 1 Diabetes and Obstructive Sleep Apnea
The purpose of the study is to investigate the role of sleep apnea in glycemic dysregulation in adults with Type 1 diabetes.
- Trial name
- T1D and OSA (NCT06915831)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Sleep Apnea, Sleep Apnea, Obstructive
A Study to Investigate the Feasibility and Respiratory Effects of Stimulating Two Functional Targets (Neural and/or Muscular) for the Treatment of Obstructive Sleep Apnea
This proof-of-concept study is to collect acute and short-term sub-acute (if applicable) changes in respiratory parameters following the percutaneous placement of electrode arrays.
- Conditions
- Sleep Apnea, Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Sleep Disorder
- Trial name
- NCT06627127
- Testing
- Target stimulation (HGN, AC, GG, Strap muscles)
- Where
- 4 sites in Australia
- Volunteers
- 35 people
- Sponsor
- Invicta Medical Inc.
Obstructive Sleep Apnea (OSA)
Intermittent-Hypoxia Inhibits Neutrophil Extracellular Traps Formation: Role of Cathelicidins
The study will enroll 80 moderate-to-severe Obstructive sleep apnea (OSA) patients (40 obese) and 40 age-, gender-, and body mass index-matched controls.
- Trial name
- NCT07129486
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kun-Ta Chou
Pediatric Obstructive Sleep Apnea
Pediatric Obstructive Sleep Apnea Among Dental Interns in Egyptian Universities
Pediatric obstructive sleep apnea (OSA) is a common yet underdiagnosed sleep-related breathing disorder in children that may result in serious health and behavioral complications if left untreated.
- Trial name
- NCT07604831
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obstructive Sleep Apnea
Registry Study on Prescription, Patient Pathways, Therapy Efficacy and Usage of Mandibular Advancement Devices in Obstructive Sleep Apnea - PATT-OSA Registry
During sleep, the muscle tonus in the oropharyngeal space is lost, the tongue might fall back andthe volume of the pharynx decreases. Air cannot pass through as it would in the awake state and thus airflow limitations occur.
- Trial name
- PATT-OSA (NCT03924817)
- Where
- 4 sites in Germany
- Volunteers
- 500 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
Comparison of Two Oral Appliances in the Treatment of Sleep Apnea Syndrome
Monocentric comparative group study comparing the efficacy and short-term tolerance of a propulsion type oral appliance (Herbst) with a retention type device (ORM) used in the treatment of sleep apnea syndrome.
- Trial name
- NCT02763813
- Testing
- Herbst (propulsion type oral appliance), Retention type appliance (ORM)
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Hopital Foch
Obstructive Sleep Apnea
Optimizing Treatment Effects on OSA-related Clinical and Patient-centered Outcomes Among Blacks
The study is to maximize efficacy of message delivery to achieve desired Obstructive sleep apnea (OSA) adherence goal. Newly diagnosed black patients (n=390, all genders) from participating sleep clinics will be randomly exposed…
- Trial name
- NCT03354520
- Testing
- Tailored Videos, OSA Treatment, Standard Videos
- Where
- United States
- Sponsor
- NYU Langone Health
Hypertension, Obstructive Sleep Apnea
Renal Denervation in Patients With Resistant Hypertension and Obstructive Sleep Apnea
The purpose of this study is to investigate the clinical utility of renal denervation for the treatment of resistant hypertension coexisting with obstructive sleep apnea.
- Trial name
- NCT01366625
- Testing
- Renal denervation with a catheter-based procedure (Symplicity® Catheter System)
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Sleep Apnea, Obstructive
Establishment of a Diagnosis and Treatment System for Information Processing Damage in Children With OSAHS
Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common childhood sleep disorder with an incidence of 3% . Studies have confirmed that OSAHS can cause multiple systemic dysfunction in children, especially affecting…
- Trial name
- NCT04080089
- Testing
- Surgical treatment, drug therapy, remote cognitive training
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Obstructive Sleep Apnea
Effectiveness of an E-health Intervention in Patients With Obstructive Sleep Apnoea
Obstructive sleep apnoea is a highly burdensome condition that not only impairs function but also confers a risk of cardiovascular disease.
- Trial name
- NCT05380726
- Testing
- Patient education
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Universitat de Lleida
Obstructive Sleep Apnea Syndrome
Validation of Functional Imaging as Predictive Tool for Outcome of Mandibular Replacement Appliance Therapy in Obstructive Sleep Apnea Hypopnea Syndrome Patients
In this open prospective study 40 patients who received Mandibular Replacement Appliance (MRA) Therapy as treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) will be included.
- Trial name
- NCT01524510
- Testing
- CT scan, Alice PDx polygraphy
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Antwerp
Obesity, Class III, Sleep Apnea, Obstructive
High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea
The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg/m²) and obstructive sleep…
- Conditions
- Obesity, Class III, Sleep Apnea, Obstructive, Inspiratory Muscle Training
- Trial name
- NCT07469280
- Testing
- High-Intensity Progressive Inspiratory Muscle Training (IMT)
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of the State of Santa Catarina
Obstructive Sleep Apnea
Effects of Different Treatment Modalities for Obstructive Sleep Apnea on Temporomandibular Joint
this study aims to evaluate the subjective symptoms, clinical and radiographic signs of temporomandibular disorders related to the use of CPAP, MAD and physical therapy in the treatment of patients with obstructive sleep apnea.
- Trial name
- NCT05510882
- Testing
- different treatment modalities for OSA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Physical Activity, Sleep Apnea
Examining the Association Between Physical Activity and Sleep Quality in Children With Autism Spectrum Disorder
This study aims to investigate whether physical activity intervention would be effective to improve sleep quality in children with ASD, and investigate how physical activity impacts on sleep in children with ASD through…
- Conditions
- Physical Activity, Sleep Apnea, Autism Spectrum Disorder
- Trial name
- NCT03348982
- Testing
- Jogging program
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
Gastroesophageal Reflux, Sleep Apnea
Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea
Patients with a clinically indicated sleep study will be enrolled in this study. They will have a diagnostic and a therapeutic sleep study with continuous positive airway pressure ventilation.
- Trial name
- NCT00194376
- Testing
- Continuous positive airway pressure ventilation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea Syndrome
Inflammatory Markers in Infants With Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) is a common disorder in children (2-3%). OSAS in turn, is associated with significant behavioral, learning, and heart problems.
- Trial name
- NCT01058590
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Obstructive Sleep Apnea
Airway Muscle Training for Obstructive Sleep Apnea
The purpose of this research study is to determine if muscle training will improve snoring and obstructive sleep apnea. Subjects will receive a sleep study to determine the severity of their apnea.
- Trial name
- OSA (NCT02259660)
- Testing
- Respiratory muscle strength training
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Florida
Respiratory Failure, Neuromuscular Disease
Ventilator Monitoring in Early Exacerbation Detection
The aim of this study is to determine whether respiratory disease exacerbations (a sudden worsening of symptoms) can be predicted by variables that are monitored by non-invasive ventilators (small machines that assist breathing)…
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01644162
- Testing
- iVAPS ventilation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- ResMed
Sleep-disordered Breathing, Major Depressive Disorder
Sleep-Disordered Breathing and PAP in Perinatal Depression
The goal of this study is to understand the contribution of sleep-disordered breathing (SDB) to one of the most common and debilitating adverse pregnancy outcomes, perinatal depression.
- Trial name
- NCT02507297
- Testing
- Positive Airway Pressure (PAP)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Michigan
Obstructive Sleep Apnea
Crossover Trial of AD182 and AD504 in Obstructive Sleep Apnea
This is a randomized, 3-period, placebo-controlled, crossover study to examine the efficacy and safety of AD182 and AD504 versus placebo in patients with obstructive sleep apnea.
- Trial name
- NCT04645524
- Testing
- AD182, AD504, Polysomnography
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Apnimed
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