Clinical trials: Sleep Hypopnea
Obstructive Sleep Apnea (OSA)
Post-extubation Boussignac CPAP System in Adults With Moderate to Severe Obstructive Sleep Apnea
The purpose of this study is to assess the efficacy of the Boussignac positive airway pressure system (a mask) applied immediately following post-operative extubation in improving lung function in patients with obstructive sleep…
- Trial name
- NCT01877928
- Testing
- Boussignac CPAP device, standard CPAP
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Queen's University
Obstructive Sleep Apnea
Effect of CPAP Treatment in Women With Moderate-to-severe OSA.
The purpose of this study is to determine whether Continuous Positive Airways Pressure (CPAP) improves quality of life, cardiovascular (blood pressure) and metabolic profile (glucose and lipid metabolism) in females with…
- Trial name
- NCT02047071
- Testing
- Continuous positive airways pressure
- Where
- Spain
- Volunteers
- 307 people
- Sponsor
- Francisco Campos-Rodriguez
Obstructive Sleep Apnea
Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy
Obstructive sleep apnea (OSA) is a disorder where a person has recurrent choking episodes during sleep. Surgery can treat OSA and drug induced sleep endoscopy (DISE) is a procedure that surgeons use to evaluate the throat while a…
- Trial name
- DISE-Pulm (NCT05350332)
- Testing
- Negative Pressure Ventilator, Pulmonary Function Testing (PFT), Transcutaneous Phrenic Nerve Stimulation
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Emory University
Sildenafil, Sleep Apnea
The Effect of Sildenafil on Sleep-Disordered Breathing in Obese Patients With Sexual Dysfunction
Sildenafil has been shown to aggravate sleep-disordered breathing in patients with severe obstructive sleep apnea. The aim of the present study is to examine the frequency of sleep-disordered breathing in obese patients who are…
- Conditions
- Sildenafil, Sleep Apnea, Sexual Dysfunction, Obesity
- Trial name
- NCT00893191
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Obstructive Sleep Apnea Syndrome
Cost-utility Study of Continuous Positive Airway Pressure Treatment in Obstructive Sleep Apnea Syndrome Patients
The purpose of this study is to estimate the cost-utility of continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea (OSA) patients in Sao Paulo city, Brazil, after 3 years of treatment and to estimate the…
- Trial name
- NCT01590420
- Testing
- CPAP S8- Scape / Resmed
- Where
- Brazil
- Volunteers
- 1,000 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Sleep-disordered Breathing, Chronic Heart Failure
Validation of the "ApneaScan" Algorithm for the Detection of Sleep Disordered Breathing in Chronic Heart Failure
A prospective observational multi-centre study for the validation of the ApneaScan algorithm (integrated in ICD devices (with or without cardiac resynchronization therapy function) of the "Incepta" series for the screening of…
- Trial name
- VASA (NCT01979120)
- Where
- 14 sites in Austria, Germany and 2 more
- Volunteers
- 200 people
- Sponsor
- Dr. Christoph Schukro
OSAHS, Gastrointestinal Endoscopy
Observation of Clinical Effect of New Oropharyngeal Airway in Patients With OSHAS During Painless Gastroenteroscopy
the(obstructivesleepapneahypoapneasyndromeOSAHS) is a kind of to sleep appear periodically in the process of syndrome characterized by partial or complete obstruction of upper respiratory tract.Patients with obstruction during…
- Conditions
- OSAHS, Gastrointestinal Endoscopy, Airway Complication of Anesthesia
- Trial name
- NCT06594380
- Testing
- Group using new oropharyngeal airway (experimental group), Endoscopic bite group (control group)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Obstructive Sleep Apnea, Snoring
A Disposable Device NAS to Treat Obstructive Sleep Apnea and Snoring
The purpose of this research study is to test a new approach for treating patients with obstructive sleep apnea and/or snoring. The new nasal device, nastent (NAS: nasal airway stent), appears to be a useful alternative or…
- Trial name
- NCT02928770
- Testing
- Nastent
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obstructive Sleep Apnea
Fentanyl Test in Children's Adenotonsillectomy
The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested…
- Trial name
- NCT02484222
- Testing
- Fentanyl
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Mild Obstructive Sleep Apnea, Snoring
Study to Examine the Effect of Silicone Mouth Tape on Snoring and Mild Sleep Apnea.
Snoring is a common problem caused by vibration of tissues in the throat region during sleep. Although snoring is sometimes dismissed as a minor nuisance rather than a medical disorder, several studies indicate that snoring can…
- Trial name
- MTASSA (NCT06587256)
- Testing
- Mouth Tape
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Obstructive Sleep Apnea of Adult, Screening
Smartwatch-Based AI Model for OSA Prediction (SWOSA)
This study aims to develop an artificial intelligence (AI) model for more accurately diagnosing obstructive sleep apnea (OSA) by collecting blood oxygen saturation and other health information during sleep using a smartwatch.
- Conditions
- Obstructive Sleep Apnea of Adult, Screening, Smart Watch
- Trial name
- NCT06792188
- Testing
- Galaxy Watch 4, Samsung Electronics Co., Ltd., South Korea
- Where
- South Korea
- Volunteers
- 147 people
- Sponsor
- Seoul National University Hospital
Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h), Intracranial Aneurysm Size
Incidence and Effects of Sleep Apnea on Intracerebral Aneurysms
Patients with intracerebral aneurysm will be screened for sleep apnea using out of center polysomnography/polygraphy. Baseline blood pressure and medication will be assessed.
- Conditions
- Sleep Apnea (Defined as Apnea Hypopnea Index > 5/h), Intracranial Aneurysm Size, Blood Pressure Medication, Comorbidities
- Trial name
- IESA (NCT02880059)
- Testing
- Cardiorepiratory Polygraphy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bonn
Obstructive Sleep Apnea of Adult
Acceptable Pressure Range for Continuous Positive Airway Pressure(CPAP) Treatment
Compliance of continuous positive airway pressure （CPAP） derived from auto-titration is similar to that derived from manual titration, although pressure derived from the former was usually 2-5 cmH2O higher than the latter.
- Trial name
- NCT04925466
- Testing
- CPAP at pressure of 10 cmH2O, CPAP at minimal effective pressure
- Where
- China
- Volunteers
- 40 people
- Sponsor
- State Key Laboratory of Respiratory Disease
Snoring, Obstructive Sleep Apnea
Intraoral Tongue Stimulation for Treatment of Primary Snoring
Intraoral Neuromuscular Training for Treatment of Snoring Objective Studies show that improving pharyngeal muscle tone can ameliorate obstructive sleep apnoea (OSA) and snoring.
- Trial name
- NCT03829956
- Testing
- Intraoral tongue stimulator (Snoozeal)
- Where
- United Kingdom
- Volunteers
- 115 people
- Sponsor
- Signifier Medical Technologies
Central Sleep Apnea
Post Approval Study of the remedē System
Prospective, single arm cohort study to evaluate the long-term safety, long-term effectiveness, and survival rate in subjects implanted with the remedē System.
- Trial name
- NCT03425188
- Where
- 17 sites in United States, Germany
- Volunteers
- 53 people
- Sponsor
- Respicardia, Inc.
Sleep-Disordered Breathing
Incorporating Flow Limitation Into the Diagnosis and Quantification of Sleep Disordered Breathing
The diagnosis and treatment of sleep disordered breathing have come to the forefront of clinical medicine following recognition of the high prevalence and associated morbidity of sleep apnea.
- Trial name
- NCT00004569
- Testing
- Non-invasive technique to diagnose and quantitate sleep-disordered breathing
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Obstructive Sleep Apnea, Sleep Apnea
Recording of Multiple Nights Using a New Contactless Device (Sleepiz One Connect) in Obstructive Sleep Apnea
The need for multiple night testing is well recognized in sleep medicine because of a considerable and relevant night-to-night variability.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Respiratory Tract Disease, Respiration Disorder
- Trial name
- NCT05134402
- Testing
- Sleepiz One Connect
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Samuel Tschopp
Obstructive Sleep Apnea (OSA)
Vent Flow Study of Prototype Nasal CPAP Mask
As continuous positive airway pressure is the treatment choice for OSA, a mask is vital in ensuring the effectiveness of therapy delivery. The study will evaluate the performance of a new mask system with diffuse vent technology.
- Trial name
- GVFECT (NCT02805777)
- Testing
- CPAP mask
- Sponsor
- ResMed
OBSTRUCTIVE SLEEP APNEA
Obstructive Apnea in Patients Submitted to Partial Laryngectomy
The investigators intend to study the prevalence of obstructive apnea in patients submitted to partial laryngectomy by larynx cancer. Volunteers will be evaluated using polissonografy.
- Trial name
- NCT01157286
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital do Servidor Publico Estadual
Obstructive Sleep Apnea
Promoting Continuous Positive Airway Pressure (CPAP) Adherence
The proposed research will evaluate new approaches to improving the ability of patients with obstructive sleep apnea (OSA), a breathing disorder during sleep, to use continuous positive airway pressure (CPAP), a medical device…
- Trial name
- NCT01335854
- Testing
- Web-based Access to CPAP Data, Web-based Access to CPAP Data with Financial Incentive
- Where
- 2 sites in United States
- Volunteers
- 135 people
- Sponsor
- University of Pennsylvania
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