Clinical trials: Sleep Hypopnea
Asthma, Sleep Apnea Syndromes
Service Development: Assessing Non-attendance Rates in Outpatient Clinics
Many studies have shown a high non-attendance rate in hospital outpatient clinics. The investigators have found a non-attendance rate of 25% in their asthma clinics and would like to investigate whether a reminder phone call will…
- Conditions
- Asthma, Sleep Apnea Syndromes, Tuberculosis, COPD
- Trial name
- NCT00129649
- Testing
- Telephone reminder call
- Where
- United Kingdom
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Obstructive Sleep Apnea
Lifestyle Interventions for Seniors With Apnea
The overall goal of this study is to determine the efficacy of a lifestyle intervention, consisting of a weight loss diet and exercise on sleep apnea in older adults.
- Trial name
- NCT01422863
- Testing
- Lifestyle Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sleep Apnea, Obstructive
Safety Study of Quickclot for Bleeding Control After Adenotonsillectomy
Hemostasis will be achieved during Pediatric Tonsillectomy/Adenoidectomy with the use of QuickClot.
- Trial name
- NCT01863563
- Testing
- QuickClot
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Eastern Virginia Medical School
Obstructive Sleep Apnea, Restless Leg Syndrome
New Data Analysis Methods for Actigraphy in Sleep Medicine
The purpose of this study is to develop statistical and informatics tools for analyzing and visualizing Actical™ (actigraphy) data linked to fatigue in Sleep Medicine Center patients.
- Conditions
- Obstructive Sleep Apnea, Restless Leg Syndrome, Insomnia
- Trial name
- NCT00949858
- Where
- United States
- Volunteers
- 635 people
- Sponsor
- Washington University School of Medicine
Hypertension, Resistant to Conventional Therapy, Obstructive Sleep Apnea
CPAP Effect on Blood Pressure and Arterial Stiffness in Obstructive Sleep Apnea Patients With Resistant Hypertension
Resistant hypertension is defined as uncontrolled blood pressure (BP ≥ 140/90mmHg) despite the current use of three or more antihypertensive drugs at full doses, including a diuretic.
- Trial name
- POP-ART (NCT02385864)
- Where
- 4 sites in France
- Volunteers
- 166 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
Respiratory Drive on Obstructive Apnea
This study is being conducted to determine whether inhaling exhaled carbon dioxide is effective for the treatment of sleep apnea.
- Trial name
- NCT01961648
- Testing
- Rebreathing bag, Mask
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- University of Manitoba
Sleep Apnea, Obstructive
Effect of Dalfampridine (4-AP) on Genioglossus Muscle Activity in Healthy Adults
In this protocol the investigators will test the effect of dalfampridine (a potassium channel blocker) on genioglossus muscle activity (EMG GG) during wakefulness and sleep in healthy control subjects.
- Trial name
- APIGLOSS (NCT02656160)
- Testing
- Dalfampridine
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea, Obstructive, Obesity
Life-style Changes in Obstructive Sleep Apnea
The primary aim is to study whether a tailored behavioural medicine intervention addressing physical activity and eating habits have additional effects to continuous positive airways pressure (CPAP) in patients with moderate or…
- Trial name
- NCT01102920
- Testing
- Behavioural strategies to promote physical activity and weight loss, CPAP
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Uppsala University
Obstructive Sleep Apnea
Oropharyngeal Exercises to Treat Obstructive Sleep Apnea
The goal of this study is to determine whether a randomized controlled trial using oropharyngeal exercises to treat sleep apnea is feasible.
- Trial name
- NCT05678088
- Testing
- Oropharyngeal Exercises
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Sunnybrook Health Sciences Centre
Obstructive Sleep Apnea
Workflow Validation of an In-Home Feedback Controlled Mandibular Positioner
The purpose of the study is to test the workflow of the MATRx and MATRx plus feedback controlled mandibular positioner in its intended setting and considerations related to decision making by the care provider.
- Trial name
- NCT03616327
- Testing
- MATRx in-lab, MATRx plus
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Zephyr Sleep Technologies
Sleep Apnea
Rainbow Acoustic Monitoring (RAM) Clinical Engineering Data Collection
To capture high resolution waveform data and numerical data from investigational and FDA-released RAM sensors in the neonatal, infant, pediatric, and adult patient population
- Trial name
- NCT03120897
- Testing
- RAM sensor
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Masimo Corporation
Obstructive Sleep Apnea of Adult
Use of Intraoral Suction and Its Effects on Obstructive Sleep Apnea
To learn whether stabilization of the tongue using intraoral suction is tolerable and what effects this approach has on sleep parameters in obstructive sleep apnea.
- Trial name
- NCT05489562
- Testing
- Intraoral Suction
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Boston Healthcare System
Obesity Hypoventilation Syndrome
Prevalence of Obesity Hypoventilation Syndrome
Rationale of the "BIO-OHS" study (Prevalence of Obesity Hypoventilation Syndrome): The overall prevalence of Obesity Hypoventilation Syndrome (OHS) has never been directly assessed in the general population.
- Trial name
- BIO-OHS (NCT01903135)
- Testing
- Blood test analysis in the clinical labs, Pneumologist consult to establish the diagnosis of OHS
- Where
- 5 sites in France
- Volunteers
- 1,004 people
- Sponsor
- AGIR à Dom
Sleep Apnea Syndromes, Snoring
Screening for Sleep Disordered Breathing With Minimally Obtrusive Sensors
The purpose of this study is to learn more about breathing disorders during sleep. The investigators want to learn how breathing sounds made during sleep relate to breathing disorders during sleep.
- Trial name
- NCT02470182
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Apnea (Central and Obstructive)
Fluid Shift on Obstructive and Central Sleep Apnea
Fluid retention in the legs due to chronic heart failure (CHF) during the daytime may redistribute to neck when with supine positioning at night.
- Trial name
- NCT02349997
- Testing
- no interventions
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Nanjing Medical University
Obstructive Sleep Apnea of Child
The Effect of Self-care Emphasizing on Balloon-Blowing Exercise Program on Severity of Sleep Apnea and Respiratory Muscle Strength Among School Age Children With Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a common condition in school-age children, often leading to sleep disturbances and associated health issues.
- Trial name
- "SEES" (NCT06780982)
- Testing
- Balloon-Blowing exercise program, Standard nursing care
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Chulalongkorn University
Obstructive Sleep Apnea of Adult
Comparative Study of the ANNE™ One System to Diagnose Obstructive Sleep Apnea
The main objective of this study is to evaluate the accuracy of the ANNE Sleep system for the diagnosis of obstructive sleep apnea (OSA) in adults
- Trial name
- NCT04643782
- Testing
- ANNE Sleep
- Where
- 4 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obstructive Sleep Apnea
Validity of a Home Respiratory Polygraphy for the Diagnosis of Obstructive Sleep Apnea in Children (DINISAS)
To assess the diagnostic validity and cost-effectiveness of a home respiratory polygraphy (HRP) performed at home compared with the standard polysomnography (PSG) in children with clinically suspected Obstructive Sleep Apnea…
- Trial name
- DINISAS (NCT03449550)
- Testing
- Home Respiratory Polygraphy (HRP), Standard Polysomnography (PSG)
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- Hospital Universitario Araba
Obstructive Sleep Apnoea Syndrome, Nasal Obstruction
Nasal Obstruction in Sleep Apnea Patients Compared to the General Population
Recent clinical findings of research at Trondheim University Hospital suggest that surgical correction of the nose septum in addition to volume reduction of the nose cavity may be beneficial in patients who suffer from both nose…
- Trial name
- NCT01282125
- Where
- Norway
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Obstructive Sleep Apnea (OSA)
The ATLAST Long-Term Study
The Study is a multi-center, prospective, open label, single-arm, three-month, long-term study of the Attune Sleep Apnea System for the treatment of obstructive sleep apnea (OSA).
- Trial name
- NCT01476917
- Testing
- Attune Sleep Apnea System
- Where
- 6 sites in United States
- Volunteers
- 39 people
- Sponsor
- ApniCure, Inc.
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