Clinical trials: Sleep Hypopnea
Obstructive Sleep Apnea
Enhancing PAP Adherence Among Spanish-speaking Hispanic Adults With OSA
This study seeks to enhance long-term positive airway pressure (PAP) adherence among Spanish-speaking Hispanic adults, a group with known PAP outcomes disparities.
- Trial name
- NCT05618444
- Testing
- Automated Management (AM)
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Geisinger Clinic
Obstructive Sleep Apnea (OSA)
IOS Parameters and PAP Titration Pressure in Obstructive Sleep Apnea
This prospective observational study aims to investigate whether impulse oscillometry (IOS)-a non-invasive lung function test-can help predict the specific pressure settings needed for positive airway pressure (PAP) therapy in…
- Trial name
- IOS-PAP (NCT07554430)
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Mustafa Kemal University
Sleep Apnea, Obstructive
The Induction of IL-6 by NF-kB in PBMC in OSA
Aim of study: 1. To compare the level of IL-6 mRNA expression in peripheral blood monocytes between normal subjects and patients with OSAS 2.
- Trial name
- OSA (NCT00498381)
- Testing
- CPAP
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Obstructive Sleep Apnea
Effect of Upper Airway Stimulation on Vascular Function in Obstructive Sleep Apnea
This study will evaluate the effect of hypoglossal nerve stimulation (HGNS) on different measures of cardiovascular function in patients with obstructive sleep apnea (OSA).
- Trial name
- NCT03051165
- Testing
- Hypoglossal Nerve Stimulation Treatment Withdrawal
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Emory University
Sleep Apnea, Obstructive
Virtual Surgery of the Upper Airways
Obstructive sleep apnea (OSA) is a sleep related breathing disorder caused by repetitive collapses of the upper airways resulting in impaired breathing, oxygen desaturation and sleep disturbances.
- Trial name
- VirtuOSA (NCT04829201)
- Testing
- functional septorhinoplasty or oropharyngeal/orthognathic surgery
- Where
- 2 sites in Norway
- Volunteers
- 30 people
- Sponsor
- Norwegian University of Science and Technology
Obstructive Sleep Apnea
Evaluation of Treatment Efficacy of a Modified Positive Airway Pressure Device to Treat Obstructive Sleep Apnea
This study will investigate the efficacy of the FPH modified positive airway pressure (PAP) device with or without SensAwake; and with different pressure support in OSA participants; in both an in-home and in-lab environment.
- Trial name
- NCT02971436
- Testing
- FPH Device with SensAwake On + Pressure Support A, FPH Device with SensAwake Off + Pressure Support A, FPH Device with SensAwake On + Pressure Support B
- Where
- 2 sites in New Zealand
- Volunteers
- 29 people
- Sponsor
- Fisher and Paykel Healthcare
Narcotic Use, Central Sleep Apnea
Diagnosis of Sleep-Related Respiratory Disorders in Patients With Narcotic Medications
The present study is a prospective, single cohort study involving patients on narcotic medications, undergoing overnight sleep studies in the clinical sleep laboratory.
- Trial name
- WP-NARC001 (NCT03670914)
- Testing
- WatchPAT 200
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
OSA, Adherence, Patient
Adherence to CPAP in Patients With OSA. Ten Year Follow up
The management of OSA is aimed to improve symptoms and mitigate reduce other health consequences. Continuous Positive Airway Pressure (CPAP) is the recognized treatment for OSA, able to reverse the pathophysiology of OSA and…
- Conditions
- OSA, Adherence, Patient, CPAP
- Trial name
- NCT03644121
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- Maugeri Foundation
Obstructive Sleep Apnea
Effect of Montelukast Therapy in Obstructive Sleep Apnea(OSA) Children
The investigators leading hypotheses are: Oral therapy with montelukast may lead to improved sleep study findings in children with mild to moderate Obstructive Sleep Apnea Syndrome (OSAS) who require surgical removal of adenoids…
- Trial name
- 32543 (NCT01027806)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Chicago
Obstructive Sleep Apnea (OSA)
Effects of Audiovisual Distraction on Desaturation and Airway Intervention in OSA-patients
Patients will be randomly assigned to either one of two groups: 1. Standard of care sedation 2. Audiovisual distraction during surgery and in the recovery room using video goggles and headphones; patients can choose a movie from…
- Trial name
- AVD (NCT03020914)
- Testing
- Audiovisual Distraction
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
OSA
Ambulatory Versus Conventional Approach Diagnosing OSA
Very few studies have examined different models of care involving initial ambulatory home-based diagnosis in diagnosing obstructive sleep apnea (OSA), identifying patients who benefit from continuous positive airway pressure…
- Trial name
- NCT01828216
- Testing
- Home sleep study, conventional polysomnography
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Chinese University of Hong Kong
Heart Failure, Congestive, Sleep Apnea Syndromes
Evaluation of a Portable Device for Assessing Sleep Disordered Breathing in Congestive Heart Failure
The purpose of this study is to evaluate an approved, portable device for assessing Sleep Disordered Breathing in Congestive Heart Failure.
- Trial name
- NCT00493948
- Testing
- ApneaLink
- Where
- Australia
- Volunteers
- 35 people
- Sponsor
- ResMed
Respiratory Disease, Substance-Related Disorders
Development of the Drug and Alcohol Respiratory Health Test
The goal of this study is to develop a brief Drug and Alcohol Respiratory Health Test (DARHT) and offer it for routine use in clinical assessment and medical reviews
- Conditions
- Respiratory Disease, Substance-Related Disorders, COPD, Asthma
- Trial name
- DARHT (NCT06921278)
- Where
- United Kingdom
- Volunteers
- 260 people
- Sponsor
- King's College London
Obstructive Sleep Apnea
Impact of Myofuntional Therapy Program on Increasing Tongue Strength and Improving Sleep Apnea
This Research studies for compare muscle strength among OSA patients who treat with myofunctional therapy program in Rajavithi hospital
- Trial name
- NCT05043389
- Testing
- myofunctional therapy program
- Where
- Thailand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Subarachnoid Hemorrhage, Sleep Apnea
Effect of Sleep Apnea on Blood Pressure Control and Outcome Early After Subarachnoid Hemorrhage
In this observational study patients with subarachnoid hemorrhage (SAH) will be screened for sleep apnea (SA) to investigate if SA is associated with impaired blood pressure control and worse clinical outcome early after SAH.
- Trial name
- NCT02724215
- Testing
- Sleep Apnea Screening (Out of Center Polysomnography Device)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bonn
OSA - Obstructive Sleep Apnea, Obesity
A Study of XW003 in Obese Participants With Obstructive Sleep Apnea Receiving Positive Airway Pressure Therapy
The aim of the study is to assess the efficacy and safety of XW003 injections in obese participants with OSA receiving PAP
- Trial name
- NCT07434050
- Testing
- XW003 injection
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Hangzhou Sciwind Biosciences Co., Ltd.
Obstructive Sleep Apnea
Increasing the Use of an Anti-snoring Mouth Guard (Mandibular Advancement Appliance) to Prevent Upper Airway Collapse During Sleep in Patients With Obstructive Sleep Apnoea.
Obstructive Sleep Apnoea (OSA) is a sleep-related breathing disorder that is characterized by the repeated collapse of the upper airway during sleep, resulting in sleep deprivation.
- Trial name
- IPOSAT (NCT04092660)
- Testing
- Behaviour change Intervention Based on Health Action Process Approach Model, Mandibular Advancement Appliance (MAA) or Anti-snoring mouth guard
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Queen Mary University of London
Obstructive Sleep Apnea (OSA)
The ATLAST Long-Term Study
The Study is a multi-center, prospective, open label, single-arm, three-month, long-term study of the Attune Sleep Apnea System for the treatment of obstructive sleep apnea (OSA).
- Trial name
- NCT01476917
- Testing
- Attune Sleep Apnea System
- Where
- 6 sites in United States
- Volunteers
- 39 people
- Sponsor
- ApniCure, Inc.
Obstructive Sleep Apnea-hypopnea Syndrome (OSAHS)
Study of the Effect of an Elastic Compression Medical Device, on Water Balance Change in Healthy Subjects
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is characterized by the occurrence of abnormally frequent episodes of interrupted ventilation (apnea) or significant reduction of ventilation (hypopnea) during sleep.
- Trial name
- NCT04911725
- Testing
- Elastic Compression Prototype
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Laboratoires Innothera
Obstructive Sleep Apnea of Child
Evidence-based Pediatric Obstructive Sleep Apnea Detection
The goal of this clinical trial is to test whether a health communication message (infographic about obstructive sleep apnea; OSA) seen by parents whose children have OSA symptoms will be helpful in identifying children with OSA.
- Trial name
- NCT05908110
- Testing
- Health Communication Message
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
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