Clinical trials: Sleep Hypopnea
Cardiovascular Diseases
Novel Strategies for Reducing Heart Disease Risk Disparities
This Western Pennsylvania-based study will (1) improve cardiovascular risk stratification to identify high-risk populations, (2) identify differences in cardiovascular risk, (3) evaluate mechanisms for population differences in…
- Trial name
- HeartSCORE (NCT00143923)
- Testing
- Nutrition, Exercise, Stress Management Counseling, usual care
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obstructive Sleep Apnea
Fentanyl Test in Children's Adenotonsillectomy
The purpose of this study is to discuss the relationship between the result of fentanyl test and required dosage of morphine for children with OSAS after adenotonsillectomy；and to evaluate the ability of predicting requested…
- Trial name
- NCT02484222
- Testing
- Fentanyl
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Obstructive Sleep Apnea Syndrome
Efficacy of Additional Titration During Oral Appliance Treatment for Sleep-disordered Breathing.
In the protocol "Predicting therapeutic outcome of mandibular advancement device treatment in obstructive sleep apnea (PROMAD)", 100 patients with obstructive sleep apnea are included and started MAD treatment at 75% of maximal…
- Trial name
- NCT01666886
- Testing
- Mandibular Advancement Device (MAD)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Obstructive Sleep Apnea Syndrome
Study to Investigate Sleep Apnea Patients at Altitude
The purpose of the study is to investigate the effect of an altitude sojourn on patients with the obstructive sleep apnea syndrome
- Trial name
- NCT00514826
- Testing
- altitude exposure
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Obstructive Sleep Apnea
Study of Effects of Sutures on Results of Palate Surgery for Obstructive Sleep Apnea
In this study we will examine whether suture repair of the palate, or roof of mouth, has any effect on results of palate surgery performed for treatment of obstructive sleep apnea.
- Trial name
- NCT00205543
- Testing
- uvulopalatopharyngoplasty with or without sutures
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Virginia Commonwealth University
Healthy, Healthy Adult
Sleep-Assessment in Patients Between High Altitude HA vs. Sea Level LA in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level on sleeping parameters by polygraphy in healthy individuals, who live permanently >2600m.
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07801950
- Testing
- Descent from 2850m to sea level and re-ascent back to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
OSA
Continuous Positive Airway Pressure (CPAP) for Primary Care
The objective of the study is to compare the results of a follow-up and treatment coordinate and interactive program performed by the General Practitioners (GP) for Obstructive Sleep Apnea (OSA) patients treated with positive…
- Trial name
- CPAP-SU-MAP (NCT02459548)
- Testing
- Follow up in Sleep Unit Group, Follow up in Primary Care Group
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Hospital Universitario Araba
Obstructive Sleep Apnea Syndrome
Air Leakage Under Continuous Positive Airway Pressure
The software embedded in recent continuous positive pressure devices enables the analysis of the level of leakage that occurs during treatment around the mask or from the mouth.
- Trial name
- SAS-leak-1 (NCT03381508)
- Testing
- Brizzy continuous positive pressure device
- Where
- 3 sites in France
- Volunteers
- 79 people
- Sponsor
- University Hospital, Montpellier
Diabetes, Obstructive Sleep Apnea
Impact of CPAP Treatment on Arterial Stiffness in Patients With T2DM and Newly Diagnosed Obstructive Sleep Apnoea
The purpose of the trial is to investigate the effects of three months' treatment with a CPAP-device versus control group on change in arterial stiffness in type 2 diabetes (T2D) patients with newly detected Obstructive Sleep…
- Trial name
- NCT02482584
- Testing
- CPAP, Control
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Nordsjaellands Hospital
Obstructive Sleep Apnea
Automated Graduated CPAP (AGPAP) for Improved Adherence in Newly Diagnosed Obstructive Sleep Apnea (OSA) Patients
Although positive airway pressure (PAP) is a highly effective treatment for sleep apnea, adherence to therapy remains an obstacle.
- Trial name
- NCT01450540
- Testing
- REMstar Auto A-Flex, modified REMstar Auto A-Flex with AGPAP
- Where
- 5 sites in United States
- Volunteers
- 241 people
- Sponsor
- Philips Respironics
Sleep Apnea, Obstructive
Obstructive Sleep Apnea and Biomarkers of Alzheimer's Disease
Clinical trial on the effect of continuous positive pressure (CPAP). Objectives: 1) To compare biomarkers of Alzheimer's disease in plasma samples from patients with Obstructive sleep apnea (OSA) and without OSA.
- Trial name
- NCT04905238
- Testing
- Continuous positive airway pressure
- Where
- 2 sites in Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Alberto Alonso Fernandez
Obstructive Sleep Apnea
Follow-up of Apneic Patients by Visio-consultation
Prospective multicenter open-label randomized clinical trial comparing videoconsultation to a face-to-face consultation during the follow-up of apneic patients treated by continuous positive pressure (CPAP) .
- Trial name
- VISIOSAS (NCT04547543)
- Testing
- Videoconsultation
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea, Obesity
Cardiovascular Risk Stratification in Patients With Obstructive Sleep Apnea
The purpose of this study is: 1. To determine the frequency of cardiovascular diseases in patients with OSA, obese, overweight, and lean (BMI<25) 2. To analyze the CPAP treatment over the clinical evolution of OSA patients 3.
- Trial name
- ERA (NCT00768625)
- Where
- Brazil
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Associacao Fundo de Incentivo a Psicofarmcologia
Obstructive Sleep Apnea
Treatment of Obstructive Sleep Apnea (OSA) With the da Vinci® SP™ Surgical System
It is a prospective, single center, single-arm clinical study to enroll a maximum of 25 subjects.
- Trial name
- NCT04795817
- Testing
- Transoral Robotic Surgery
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Intuitive Surgical
Sleep Apnea
Undiagnosed Sleep Apnea and Bypass OperaTion
Sleep apnea is a prevalent disorder in patients with coronary artery disease. Previous studies suggested sleep apnea was associated with coronary plaque burden and future adverse cardiovascular events after percutaneous coronary…
- Trial name
- SABOT (NCT02701504)
- Where
- Singapore
- Volunteers
- 1,000 people
- Sponsor
- National University of Singapore
Obstructive Sleep Apnea (OSA)
The Improving Sleep in African American Couples Study (ISAAC)
The goal of this randomized study is to compare a combined behavioral intervention (remote tele-monitoring and feedback, virtual cognitive behavioral couple therapy, and couple-oriented peer support) on continuous positive airway…
- Trial name
- ISAAC (NCT07447284)
- Testing
- CPAP Training and Education, Virtual Disease Support Group Sessions, Couple CPAP Training and Education
- Where
- 2 sites in United States
- Volunteers
- 440 people
- Sponsor
- MetroHealth Medical Center
Sleep Apnea, Obstructive
Heated Humidified High Flow Nasal Cannula for Children With Obstructive Sleep Apnea
The purpose of this study is to determine whether heated humidified high flow nasal cannula (HHHFNC) is effective as a treatment of obstructive sleep apnea syndrome (OSAS) compared to continues positive airway pressure (CPAP)…
- Trial name
- NCT02515409
- Testing
- HHHFNC, CPAP
- Volunteers
- 40 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Sleep Apnea, Obstructive
Humidity Under Continuous Positive Airway Pressure
Heated humidification in CPAP therapy is often not enough to prevent side effects like dryness of nasal mucosa and xerostomia, especially in cases of mouth breathing or mask leakage.
- Trial name
- NCT01462409
- Testing
- RESMed S9 with humidifier H5i and heated tube Climate Line, CPAP without humidification, CPAP with heated humidification
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- Institut für Pneumologie Hagen Ambrock eV
Sleep Apnea
Sleep Apnea. Concordance Between Non-reference and Reference Centres
When a disorder is as prevalent as sleep apnea hypopnea syndrome various medical levels and strategies should be implicated. We to evaluate the degree of concordance in management between a sleep reference centre and…
- Trial name
- NCT00424658
- Testing
- SAHS diagnosis
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Clinic of Barcelona
Obstructive Sleep Apnea
Obstructive Sleep Apnea Among Somali-Americans
The investigators seek to advance the understanding of obstructive sleep apnea as it relates to different ethnic origins as well as sex differences.
- Trial name
- Somali OSA (NCT04124848)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
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