Clinical trials: Sleep Obstructive Apnea
Obstructive Sleep Apnea
Immunological Consequences of Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a medical problem whose importance is increasing in recognition and awareness. OSA is associated with the development of hypertension and other cardiovascular diseases (1,2).
- Trial name
- NCT00214071
- Testing
- Influenza vaccine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Obstructive Sleep Apnea, End Stage Renal Disease
Effect of Beginning a Renal Replacement Therapy on Obstructive Sleep Apnea in End Stage Renal Disease Patients
The purpose of this study is to investigate the effect of beginning a renal replacement therapy on fluid overload and its consequence on the severity of obstructive sleep apnea, in patients with end stage chronic kidney disease.
- Trial name
- SASinHD_005 (NCT02073344)
- Testing
- Renal replacement therapy, no intervention
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Obstructive Sleep Apnea of Adult
Effects of Rehabilitation for Patients With Obstructive Sleep Apnea
In previous review study, it was hypothesized that a comprehensive rehabilitation can combine both local pharyngeal muscle exercise and systemic cardiopulmonary rehabilitation for the OSA patients with oropharyngeal muscle…
- Trial name
- NCT03940781
- Testing
- comprehensive rehabilitation
- Where
- Taiwan
- Volunteers
- 33 people
- Sponsor
- National Cheng-Kung University Hospital
Sleep Apnea Syndrome, Obstructive Sleep Apnea
Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
Obstructive sleep apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD) are highly prevalent chronic respiratory diseases in the Veteran population.
- Conditions
- Sleep Apnea Syndrome, Obstructive Sleep Apnea, COPD, Overlap Syndrome
- Trial name
- NCT04179981
- Testing
- Positive airway pressure, Conservative care (control arm)
- Where
- United States
- Volunteers
- 668 people
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea, Mild Cognitive Impairment
Mild Cognitive Impairment and Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) has been linked to increased risk for Alzheimer's disease (AD), but little prospective evidence exists on the effects of OSA treatment in preclinical AD.
- Trial name
- MEMORIES (NCT01482351)
- Testing
- CPAP adherence intervention, Attention control intervention
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- George Mason University
Sleep Apnea Syndrome, Oxidative Stress
NADPH Oxidase Polymorphisms in Obstructive Sleep Apnea Syndrome (OSAS)
Obstructive Sleep Apnea (OSA) is associated with increased oxidative stress. The major sources of Reactive Oxygen Species (ROS) in the vasculature are the NADPH oxidases.
- Conditions
- Sleep Apnea Syndrome, Oxidative Stress, Single Nucleotide Polymorphism
- Trial name
- NCT01141829
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep Apnea Syndrome, Obstructive, Drowsiness
Ocular Parameters in Patients With Sleep Apnea
The aim of this study is to assess the ocular parameters of drowsiness in patients with diagnosed Obstructive Sleep Apnea Syndrome through objective methods of ocular imaging and subjective evaluation methods (questionnaire)
- Conditions
- Sleep Apnea Syndrome, Obstructive, Drowsiness, Blinking, Concentration Ability Impaired
- Trial name
- NCT05911737
- Testing
- Short video and Questionnaire
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Pediatric Obstructive Sleep Apnea Syndrome
Investigating the Safety of Post-surgical Analgesics in Children With Obstructive Sleep Apnea
Every year thousands of young children with obstructive sleep apnea undergo surgery which requires them to be prescribed pain medication.
- Trial name
- NCT01680939
- Testing
- Morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Obstructive Sleep Apnea
The Impact of Venlafaxine on Apnea Hypopnea Index in Obstructive Sleep Apnea
The investigators hypothesis is that obstructive sleep apnea (OSA) patients with a low arousal threshold may wake up too early during a respiratory event, before upper airway muscles can be activated to achieve stable…
- Trial name
- NCT02714400
- Testing
- Venlafaxine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Obstructive Sleep Apnea Syndrome
The Use of Heliox in Obstructive Sleep Apnea Syndrome
The goals of the project is to evaluate the effects of Heliox therapy on obstructive sleep apnea syndrome (OSAS).
- Trial name
- HOSA (NCT02135900)
- Testing
- Heliox
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Northwell Health
Sickle Cell Disease
Sleep Study in Adult Patients With Major Sickle Cell Disease With Paroxysmal Nocturnal Events
Hypothesis is that the occurrence of nocturnal Vaso-Occlusive Crisis (VOC) and priapism in adults might be related to episodes of nocturnal desaturation secondary to a sleep apnea syndrome.
- Trial name
- DREPASOM (NCT02539771)
- Testing
- Polysomnography and blood sample
- Where
- France
- Volunteers
- 114 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
OSA
Ultrasonographic of Diaphragmatic Function in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is associated with altered respiratory mechanics, including diaphragmatic function. Ultrasonography provides a non-invasive tool to assess diaphragmatic structure and performance, which may correlate…
- Trial name
- NCT07370376
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Obstructive Sleep Apnea (OSA)
Wearable Device to Promote CPAP Adherence in Obstructive Sleep Apnea (OSA) Patients
The goal of this study type: clinical trial is to evaluate adherence for CPAP used with wearable device in OSA patients comparing with controlled group; could include any of the following: adult patients (≥ 19 yr of age) with…
- Trial name
- NCT07377968
- Testing
- garmin vivoactive 5 with self-monitoring data, Garmin vivoactive 5 without self-monitoring data
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Ramathibodi Hospital
Obstructive Sleep Apnea
The Effect of Pure Prone Positioning Therapy for the Patients With Mild to Moderate Obstructive Sleep Apnea
Efficacy of Pure Prone Positioning (PPP) treatment in improving apnea-hypopnea index (AHI) and nocturnal oxygen saturation was investigated in mild to moderate Obstructive Sleep Apnea.
- Trial name
- NCT01368952
- Testing
- Pure prone positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital
Obstructive Sleep Apnea
A Comparison of Surgical Outcome Following Drug-induced Sleep Endoscopic Diagnosis Using Propofol or Dexmedetomidine for Sedation : A Prospective Randomized Trial
Obstructive sleep apnea is a common disease, associated with cardiovascular disease, cerebrovascular disease, and many other medical conditions. Therefore the precise diagnosis and treatment are important.
- Trial name
- NCT01895348
- Testing
- Propofol, propofol-remifentanil, Dexmedetomidine-remifentanil
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Sleep Apnea Syndrome, Obstructive, Sleep Apnea Syndrome (OSAS)
The SNORE-trial: Analysis of Alterations in Sleep Stages Following Anesthesia and Their Relation to the Severity of Obstructive Sleep Apnea in the First 3 Nights After Surgery
The goal of this observational study is to learn about the relationship between sleep alterations following anesthesia and their relationship to a potential increase of obstructive sleep apnea (OSA) severity.
- Trial name
- SNORE (NCT06586268)
- Where
- 2 sites in Netherlands
- Volunteers
- 35 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
OSA
Validity of a Vibrating Postural Device for the Treatment of Positional Obstructive Sleep Apnea (Postural)
The objective of the study is validity of the effectiveness of a vibrating postural device in reduce the respiratory events (Apnea-Hypopnea Index-AHI) in patients with positional Obstructive Sleep Apnea (OSA).
- Trial name
- POSTURAL (NCT03336515)
- Testing
- Group C-Postural device activated, Group B-Postural device no activated, Group A-General Recommendation
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Hospital Universitario Araba
Overweight, Obstructive Sleep Apnea
The Influence of Bariatric Surgery on Patients With Obstructive Sleep Apnea (OSA)
Obesity is a very important risk-factor in obstructive sleep apnea (OSA) and other sleep breathing disorders in patients with extreme BMI. Candidates for bariatric surgery have a high OSA prevalence, ranging from 60-83%.
- Trial name
- OSA (NCT01573676)
- Volunteers
- 60 people
- Sponsor
- Hillel Yaffe Medical Center
Obstructive Sleep Apnea
Impact of Tele-visit on Patients Continous Positive Airway Pressure (CPAP) Follow-up by Home Care Provider
To determine the impact of telecare on continous positive airway pressure (CPAP) patients follow up by home care provider (HCP)
- Trial name
- i-tech PPC (NCT05653804)
- Testing
- tele-visit
- Where
- France
- Volunteers
- 320 people
- Sponsor
- AGIR à Dom
Obstructive Sleep Apnoea, Obesity
Peripheral Vascular Function in Obstructive Sleep Apnoea
Peripheral vascular function is impaired in people with obstructive sleep apnoea who are untreated compared with age-, weight- and sex-matched healthy controls.
- Trial name
- NCT01619748
- Where
- 2 sites in United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
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