Clinical trials: Sleep Obstructive Apnea
Sleep Apnea, Obstructive
Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep
This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is…
- Trial name
- Nasal vs Oral (NCT06789770)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea (OSA)
Digital-supported Orofacial Myofunctional Therapy in OSA
This pilot study explores the feasibility, acceptability, and preliminary effectiveness of Digital-supported Orofacial Myofunctional Therapy (d-MFT), an innovative program combining facial recognition technology with…
- Trial name
- NCT07292922
- Testing
- Digital-supported Orofacial Myofunctional Therapy
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Hong Kong Metropolitan University
Sleep Apnea Syndromes, Insomnia Disorder
Apnea and Insomnia Relief Study
The purpose of this study is to determine whether a behavioral sleep treatment improves functioning and sleep in Veterans with posttraumatic stress disorder (PTSD).
- Conditions
- Sleep Apnea Syndromes, Insomnia Disorder, Stress Disorders, Post-Traumatic
- Trial name
- AIR (NCT04007796)
- Testing
- Apnea and Insomnia Relief (AIR), Sleep Education (SE)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea, Obstructive
NPA-OSA Device Tolerability, Usability and Acclimation Clinical Study in Adult Obstructive Sleep Apnea (OSA) Patients
This pilot study is being done to determine if the nasopharyngeal airway obstructive sleep apnea (NPA-OSA) device can be used in the treatment of OSA in adults.
- Trial name
- NCT06677151
- Testing
- nasopharyngeal airway obstructive sleep apnea (NPA-OSA) device
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Obstructive Sleep Apnea, Sleep Apnea
Validity and Reliability of the 6-Minute Pegboard and Ring Test (6PBRT) in Adults With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder characterized by recurrent upper airway obstruction during sleep, leading to intermittent hypoxia and sleep fragmentation.
- Trial name
- NCT07465874
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Obstructive Sleep Apnea (OSA), Snoring
Effects of Frequency Adjustment in Functional Electrical Stimulation on Genioglossus Muscle Activity
This single-group interventional study investigates the safety and physiologic effects of functional electrical stimulation (FES) applied to the tongue and submental muscles in adults at high risk for sleep apnea.
- Trial name
- NCT07466888
- Testing
- Functional Electrical Stimulation Device
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Obstructive Sleep Apnea (OSA)
Telemonitoring With CPAP in Severe Obstructive Sleep Apnea in Primary Health Care
Obstructive sleep apnea (OSA) is a prevalent sleep disorder associated with cardiovascular, metabolic, cognitive, and psychological complications.
- Trial name
- CPAP-APS (NCT07464262)
- Testing
- CPAP Telemonitoring, CPAP Therapy
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Federal University of São Paulo
Sleep-Disordered Breathing, Obstructive Sleep Apnea
Managing Opioid Related Sleep Apnea With Acetazolamide
Patients with chronic pain who use opioids appear to be at increased risk for breathing issues during sleep, termed sleep disordered breathing (SDB).
- Conditions
- Sleep-Disordered Breathing, Obstructive Sleep Apnea, Central Sleep Apnea, Chronic Pain
- Trial name
- MORPHO (NCT06043830)
- Testing
- Acetazolamide
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Diego
Heart Failure, OSA - Obstructive Sleep Apnea
Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure
Heart failure with reduced ejection fraction (HFrEF) is a serious condition that limits daily activities and often leads to hospital stays and early death.
- Trial name
- MARVEL-HF (NCT07460505)
- Testing
- Mandibular advancement device
- Where
- Singapore
- Volunteers
- 328 people
- Sponsor
- National University Hospital, Singapore
Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea
Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF
This study will evaluate the effect of CPAP therapy on esophageal pH and lung inflammation in patients with idiopathic pulmonary fibrosis (IPF) and sleep apnea.
- Conditions
- Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea, Gastro Esophageal Reflux
- Trial name
- NCT05359965
- Testing
- Positive Airway Pressure
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Arizona
Obstructive Sleep Apnea (OSA), Polysomnography
Multimodal Deep Learning Model for Predicting the Apnea-Hypopnea Index in Obstructive Sleep
This study aims to develop a multimodal deep learning model that integrates noninvasive signals to predict the severity of obstructive sleep apnea.
- Trial name
- NCT07447999
- Testing
- electronic stethoscope, fingertip pulse oximeter, pressure-sensing mattresses
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Fu Jen Catholic University
Obstructive Sleep Apnea
A Post-market Clinical Follow up of the Genio® System for the Treatment of Obstructive Sleep Apnea in Adults
The primary objective of this study is to confirm the safety and clinical effectiveness of the Genio® system in moderate to severe Obstructive Sleep Apnea (OSA) adult patients over a period of 5 years post-surgery.
- Trial name
- EliSA (NCT04031040)
- Testing
- Genio® system therapy
- Where
- 19 sites in Belgium, France and 3 more
- Volunteers
- 110 people
- Sponsor
- Nyxoah S.A.
Obstructive Sleep Apnea (OSA)
Evaluation of the Diagnostic Capacity of a Smart Mattress Versus Conventional Polysomnography
This project aims to develop and evaluate an innovative, non-invasive diagnostic system based on a smart mattress for detecting obstructive sleep apnea (OSA), as well as assessing overall sleep quality and identifying periodic…
- Trial name
- NCT07432919
- Testing
- Integrated polysomnographic assessment with smart mattress.
- Where
- 2 sites in Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospital San Pedro de Logroño
Sleep Apnea, Obstructive
Maxillomandibular Advancement Surgery for Treatment of Obstructive Sleep Apnoea Syndrome
This study looks at how jaw surgery called maxillomandibular advancement with counterclockwise rotation affects breathing during sleep in people with moderate to severe obstructive sleep apnea who cannot tolerate standard…
- Trial name
- OSAS (NCT07446634)
- Testing
- Maxillomandibular advancement surgery with counterclockwise rotation
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Jani Talvilahti
Primary Open Angle Glaucoma, Obstructive Sleep Apnea
Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea
glaucoma is prevalent among obstructive sleep apnea (OSA). contnous passive airway pressure is main treatment of OSA. lifestyle corrections also recommended
- Conditions
- Primary Open Angle Glaucoma, Obstructive Sleep Apnea, Obesity
- Trial name
- NCT07447011
- Testing
- lifetyle corrections and CPAP, CPAP
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Obstructive Sleep Apnea, Obesity
Underlying Mechanisms of Obesity-induced Obstructive Sleep Apnea
Obesity is a common risk factor for the development of obstructive sleep apnea. However, not all subjects with obesity develop obstructive sleep apnea.
- Trial name
- Slim-OSA (NCT04793334)
- Testing
- sleeve gastectomy
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Brandon Nokes
Adenotonsillectomy, Obstructive Sleep Apnea (OSA)
Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstructive Sleep Apnea
Emphasize that the usage of multimodal analgesia in managing perioperative pain in children with mild to moderate Obstructive Sleep Apnea undergoing adenotonsillectomy may achieve the same efficacy of fentanyl with less…
- Conditions
- Adenotonsillectomy, Obstructive Sleep Apnea (OSA), Fentanyl, Opioid
- Trial name
- NCT07435493
- Testing
- Group A: Fentanyl-Based Analgesia, Group B: Opioid-Free Multimodal Analgesia
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Laparascopic Sleeve Gastrectomy, Obesity & Overweight
Impact Of Laparoscopic Sleeve Gastrectomy On Obesity-Related Comorbidities In Patients Over 65 Years
This study compares laparoscopic sleeve gastrectomy (a type of weight-loss surgery) with non-surgical care in adults aged 65 or older who have severe obesity and related health problems like type 2 diabetes, high blood pressure…
- Conditions
- Laparascopic Sleeve Gastrectomy, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07437716
- Testing
- Laparoscopic Sleeve Gastrectomy (LSG), Structured Dietary Counseling
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Sedative Effect During Drug-induced Sleep Endoscopy, Obstructive Sleep Apnea (OSA)
Combination of Remimazolam and Propofol During Drug-induced Sleep Endoscopy
This study helps patients find the optimal sedation regimen in drug-induced sleep endoscopy
- Trial name
- NCT06784479
- Testing
- Remimazolam and Propofol, Propofol, Midazolam and propofol
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Dan Liu
Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children
Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy
The goal of this treatment study is to determine if doing lateral pharyngoplasty with tonsillectomy is better for children than doing tonsillectomy alone.
- Conditions
- Sleep-Disordered Breathing, Sleep Apnea Syndromes in Children, Sleep Apnea, Obstructive, Tonsillitis
- Trial name
- NCT05575401
- Testing
- Lateral pharyngoplasty, Tonsillectomy
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Loma Linda University