Clinical trials: Sleep Obstructive Apnea
Obesity, Class III, Sleep Apnea, Obstructive
High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea
The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg/m²) and obstructive sleep…
- Conditions
- Obesity, Class III, Sleep Apnea, Obstructive, Inspiratory Muscle Training
- Trial name
- NCT07469280
- Testing
- High-Intensity Progressive Inspiratory Muscle Training (IMT)
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of the State of Santa Catarina
Obstructive Sleep Apnea
Effects of Different Treatment Modalities for Obstructive Sleep Apnea on Temporomandibular Joint
this study aims to evaluate the subjective symptoms, clinical and radiographic signs of temporomandibular disorders related to the use of CPAP, MAD and physical therapy in the treatment of patients with obstructive sleep apnea.
- Trial name
- NCT05510882
- Testing
- different treatment modalities for OSA
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gastroesophageal Reflux, Sleep Apnea
Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea
Patients with a clinically indicated sleep study will be enrolled in this study. They will have a diagnostic and a therapeutic sleep study with continuous positive airway pressure ventilation.
- Trial name
- NCT00194376
- Testing
- Continuous positive airway pressure ventilation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea Syndrome
Inflammatory Markers in Infants With Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) is a common disorder in children (2-3%). OSAS in turn, is associated with significant behavioral, learning, and heart problems.
- Trial name
- NCT01058590
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Obstructive Sleep Apnea
Airway Muscle Training for Obstructive Sleep Apnea
The purpose of this research study is to determine if muscle training will improve snoring and obstructive sleep apnea. Subjects will receive a sleep study to determine the severity of their apnea.
- Trial name
- OSA (NCT02259660)
- Testing
- Respiratory muscle strength training
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Florida
Respiratory Failure, Neuromuscular Disease
Ventilator Monitoring in Early Exacerbation Detection
The aim of this study is to determine whether respiratory disease exacerbations (a sudden worsening of symptoms) can be predicted by variables that are monitored by non-invasive ventilators (small machines that assist breathing)…
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01644162
- Testing
- iVAPS ventilation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- ResMed
Obstructive Sleep Apnea
Crossover Trial of AD182 and AD504 in Obstructive Sleep Apnea
This is a randomized, 3-period, placebo-controlled, crossover study to examine the efficacy and safety of AD182 and AD504 versus placebo in patients with obstructive sleep apnea.
- Trial name
- NCT04645524
- Testing
- AD182, AD504, Polysomnography
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Apnimed
Difficult Intubation, Airway Obstruction
Risk Prediction of Difficult Tracheal Intubation in OSAHS Patient
This study evaluates the risk factors for difficult tracheal intubation in in obstructive sleep apnea hypopnea syndrome(OSAHS) patients undergoing uvulo-palato-pharyngoplast(UPPP)
- Trial name
- OSAHS (NCT04506346)
- Testing
- difficult tracheal intubation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Lung Cancer, Obstructive Sleep Apnea
OSA in Never Smokers With Lung Cancer
Previous studies have yielded inconsistent findings regarding the association between obstructive sleep apnea and the prevalence and mortality of lung cancer.
- Trial name
- NCT05224180
- Where
- South Korea
- Volunteers
- 77 people
- Sponsor
- Seoul National University Hospital
Obstructive Sleep Apnea, Neurocognitive Disorders
Postoperative Neurocognitive Disorders
The purpose of this study is to examine the mechanisms of brain injury contributing to postoperative neurocognitive disorders (PNCD) in an at-risk population (obstructive sleep apnea (OSA)) undergoing surgery.
- Trial name
- PNCD (NCT04244162)
- Testing
- Brain Imaging, Cognitive testing, Blood Biomarkers
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital
Obstructive Sleep Apnea
Multimodal Postoperative Analgesia Following OSA Surgery
Assessment of the clinical efficacy and adverse effects of multimodal analgesic regimen consisting of nalbuphine combined with ketorolac using IV continuous infusion silicon device (Accufuser) for postoperative analgesia…
- Trial name
- NCT04483427
- Testing
- Nalbuphine, ketorolac, accufuser
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Bahaa Mohammed Refaie
Obstructive Sleep Apnea
Variable Negative External Pressure (vNEP) - An Alternative to Continuous Positive Airway Pressure (CPAP) for the Treatment of Obstructive Sleep Apnea (OSA): A Pilot Study
Non-compliance rates estimated at 50% pose a major issue for CPAP therapy, the primary treatment for OSA. Negative external pressure, applied over the anterior neck under the mandible, has shown encouraging results as an…
- Trial name
- NCT04718142
- Testing
- vNEP
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Somne, LLC
Obstructive Sleep Apnea
Testing Settings of NovaResp's cMAP® Software During Home PAP Therapy
The goal of this clinical trial is to identify which settings of proactive therapy work best in OSA patients who regularly adhere to PAP therapy at home.
- Trial name
- NCT07898254
- Testing
- Dynamic cMAP, Direct cMAP
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- NovaResp Technologies Inc
Obstructive Sleep Apnea
The Impact of Obstructive Sleep Apnea in Erectile Dysfunction
The syndrome of obstructive sleep apnea (OSA) is a common condition that affects 2-4% of the general population, causing an increase in sympathetic activity, changes in systemic blood pressure, and is associated with…
- Trial name
- NCT03086122
- Testing
- Continuous positive airway pressure
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Sleep Apnea Syndromes, Insomnia Disorder
Apnea and Insomnia Relief Study
The purpose of this study is to determine whether a behavioral sleep treatment improves functioning and sleep in Veterans with posttraumatic stress disorder (PTSD).
- Conditions
- Sleep Apnea Syndromes, Insomnia Disorder, Stress Disorders, Post-Traumatic
- Trial name
- AIR (NCT04007796)
- Testing
- Apnea and Insomnia Relief (AIR), Sleep Education (SE)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Sleep Apnea, Dyslipidemias
CPAP Effect on Lipid Profile and Hyperuricemia in Patients With Dyslipidemia and Moderate-severe Obstructive Sleep Apnea
Clinical Trial Phase IV Indication: Moderate-severe obstructive sleep apnea and dyslipidemia. Objectives: Main objective: To test whether 12 months of CPAP treatment associated with conventional pharmacological treatment improves…
- Conditions
- Sleep Apnea, Dyslipidemias, Hyperuricemia
- Trial name
- CPAPLIP (NCT06463561)
- Testing
- Continuous positive airway pressure, Hygienic-dietary recommendations and daily physical activity promotion
- Where
- Spain
- Volunteers
- 220 people
- Sponsor
- Hospital Universitario La Paz
Sleep Apnea, Obstructive, Children
Real Life Pediatric Obstructive Sleep Apnea
OBJECTIVES: PRIMARY: To analyze the cognitive alterations in children with Obstructive Sleep Apnea OSA in different age groups and changes at 12 months after treatment with a protocol based on usual clinical practice.
- Trial name
- RELIPOSA (NCT03950466)
- Where
- 2 sites in Spain
- Volunteers
- 1,200 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Obstructive Sleep Apnea
Role of Biomarkers to Screen for Obstructive Sleep Apnea
assess the relationship between obstructive sleep apnea and endocrine, inflammatory, and metabolic bio-markers in consecutively enrolled adult male patients with a clinical suspicion of obstructive sleep apnea.
- Trial name
- NCT04093102
- Testing
- biomarkers
- Volunteers
- 90 people
- Sponsor
- Assiut University
Normal Tension Glaucoma, Obstructive Sleep Apnea
Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness
The purpose of this research study is to learn more about the relationship between Obstructive Sleep Apnea (OSA) and Normal Tension Glaucoma (NTG).
- Trial name
- NCT06023927
- Testing
- Clinical observation, diagnostic testing
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Obstructive Sleep Apnea (OSA)
Atomoxetine and Oxybutynin in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is common and has major health implications but treatment options are limited. OSA patients show a marked reduction in upper airway (UA) dilator muscle activity at sleep onset and this phenomenon…
- Trial name
- ATOSA (NCT02908529)
- Testing
- Combination product of Atomoxetine and Oxybutynin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Brigham and Women's Hospital
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