Clinical trials: Sleep Obstructive Apnea
Apnea Syndrome, Apnea, Obstructive
Effect of Hypnosis on Adherence to Continuous Positive Airway Pressure.
The prevalence of sleep-disordered breathing is high, with an apnea-hypopnea index of over 15 per hour found in 49.7% of men and 23.4% of women in the general population (1).
- Trial name
- HypnOSA (NCT06397365)
- Testing
- medical hypnosis
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Solelhac Geoffroy
Snoring, Sleep Disturbances
Evaluating Sleep Quality With Emerging Technologies
To investigate the sleep quality of the adult orthodontic patient population at the Case Western Reserve University School of Dental Medicine using the NOSE Questionnaire, STOP-BANG Questionnaire, SleepCycle app, and Belun Ring.
- Conditions
- Snoring, Sleep Disturbances, Hypoxia, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT06900530
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Obstructive Sleep Apnea (OSA)
Biomarkers for Obstructive Sleep Apnea
The purpose of the study is to: recruit subjects with untreated sleep apnea; assess overnight changes in their blood and urine chemicals review the overnight changes in blood and urine chemicals after they have been treated for…
- Trial name
- BOSA (NCT00834509)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Arterial Hypertension
"Escape" Phenomenon of the Antihypertensive Therapy Efficacy
A little attention is paid to the AHT efficacy escaping problem, which can be explained by the AHT correction simplicity and rapid achievement of the target BP level.
- Trial name
- ESCAPE (NCT05436730)
- Testing
- Ambulatory blood pressure measurement device, Sphygmocor, VaSera-VS
- Where
- Russia
- Volunteers
- 165 people
- Sponsor
- Federal State Budgetary Institution NATIONAL MEDICAL RESEARCH CENTRE OF CARDIOLOGY NAMED AFTER ACADE
Obstructive Sleep Apnea
Continuous Positive Airway Pressure (CPAP) Promotion And Prognosis - the Army Sleep Apnea Program (ASAP)
The purpose of this study is to assess the efficacy of Eszopiclone in improving short and intermediate-term compliance with continuous positive airway pressure (CPAP) in patients newly diagnosed with obstructive sleep apnea (OSA).
- Trial name
- CPAPASAP (NCT00612157)
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Walter Reed Army Medical Center
Obstructive Sleep Apnea
Safety Monitoring for a Novel 3D Printed Mandibular Advancement Device
The purpose of this study is to evaluate the safety profile of the novel oral appliance (OA )device and to assess patient comfort of the novel OA device.
- Trial name
- NCT05018234
- Testing
- Noval Oral Appliance
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Sleep Apnea Syndromes
Sodium Channel Splicing in Obstructive Sleep Apnea (SOCS-OSA)
This study is designed to test whether SCN5A mRNA processing is altered in OSA patients, which may contribute to their increased arrhythmic risk, and whether processing of SCN5A mRNA is modulated by CPAP treatment.
- Trial name
- NCT02725632
- Testing
- CPAP
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rhode Island Hospital
Obstructive Sleep Apnea
Whitsundays (Nasal) Singapore External Clinical Study 1 Protocol
Each Whitsunday mask or AirFit N30i Quiet mask is worn for 7 nights. The overall purpose of this study is to evaluate the performance of the Whitsundays nasal mask system (a prototype mask) compared to the ResMed AirFit N30i…
- Trial name
- NCT05255744
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ResMed
Obstructive Sleep Apnea of Child
Endothelial Dysfunction and Oxidative Stress in Children With Sleep Disordered Breathing.
Sleep disordered breathing (SDB) is a common disease in both adults and children and is caused by the obstruction of the upper airway during sleep.
- Trial name
- NCT02247167
- Testing
- adenotonsillectomy
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Roma La Sapienza
Obstructive Sleep Apnea, Sleep Apnea
Recording of Multiple Nights Using a New Contactless Device (Sleepiz One Connect) in Obstructive Sleep Apnea
The need for multiple night testing is well recognized in sleep medicine because of a considerable and relevant night-to-night variability.
- Conditions
- Obstructive Sleep Apnea, Sleep Apnea, Respiratory Tract Disease, Respiration Disorder
- Trial name
- NCT05134402
- Testing
- Sleepiz One Connect
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Samuel Tschopp
Sleepiness, SARS-CoV2 Infection
Obstructive Sleep Apnoea Post Covid 19: Role of the Upper Airway Microbiome
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing coronavirus disease, Covid-19, has spread rapidly across the globe since its emergence in January 2020.
- Conditions
- Sleepiness, SARS-CoV2 Infection, Fatigue Syndrome, Chronic, Snoring
- Trial name
- NCT05116657
- Testing
- Nasal Lavage and Oral Wash
- Volunteers
- 50 people
- Sponsor
- Royal College of Surgeons, Ireland
Obstructive Sleep Apnea
High Flow Nasal Cannula for Obstructive Sleep Apnea
This study compare the efficacy of high flow nasal cannula with nasal continuous positive airway pressure. All of participants will be randomized to receive one night high flow nasal cannula therapy and another night for nasal…
- Trial name
- NCT03843372
- Testing
- High flow nasal cannula
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Chung-Chieh, Yu
Obstructive Sleep Apnea
The Evaluation of a Full Face Mask Seal for the Treatment of Obstructive Sleep Apnea
The investigation is a prospective, randomized, single blinded, crossover study. The investigation is designed to evaluate the performance, comfort and ease of use of the F\&P Trial Full Face Mask Seal amongst Obstructive Sleep…
- Trial name
- NCT03230877
- Testing
- Toffee full face mask with 'Improved Seal', Toffee full face mask with 'Normal Seal'
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Sleep Apnea : Diagnosis and Monitoring
This prospective study aims to evaluate a new medical screening method to detect and discriminate sleep apnea-hypopnea events. A new device called ApneaBand will be tested to propose a new screening method facilitating the…
- Trial name
- ApneaBand (NCT03571477)
- Testing
- ApneaBand
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Obstructive Sleep Apnea
Effectiveness of Stellate Ganglion Block for the Treatment of Obstructive Sleep Apnea
The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are: Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were…
- Trial name
- NCT06319612
- Testing
- routine rehabilitation treatment, Stellate ganglion block, Lidocaine Hydrochloride
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Obstructive Sleep Apnea
Phototherapy for Non-responders to Oral Appliance Therapy for Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a medical condition where a person has great difficulty with breathing, or stops breathing all together, while asleep.
- Trial name
- NCT06960200
- Testing
- Phototherapy
- Where
- Canada
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Obstructive Sleep Apnea
Assessing the Symptoms of Obstructive Sleep Apnea
The purpose of this study is to investigate the correlation between health outcomes associated with the severity of obstructive sleep apnea (OSA) symptomatology, the findings will guide the design of interventional studies.
- Trial name
- OSA (NCT01481636)
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- Bangor University
Excessive Daytime Sleepiness, Narcolepsy
Extension Study of the Safety and Efficacy of Armodafinil in the Treatment of Patients With Excessive Sleepiness
A 12 Month, Open-Label, Flexible Dosage Extension Study of the Safety and Efficacy of Armodafinil (CEP-10953) in the Treatment of Patients with Excessive Sleepiness Associated with Narcolepsy, Obstructive Sleep Apnea/Hypopnea…
- Conditions
- Excessive Daytime Sleepiness, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, Chronic Shift Work Sleep Disorder
- Trial name
- NCT00228553
- Testing
- Armodafinil 100 to 250 mg/day
- Where
- 100 sites in United States, Australia and 5 more
- Volunteers
- 743 people
- Sponsor
- Cephalon
Obstructive Sleep Apnea
Measuring Effectiveness in Sleep Apnea Surgery
The goal of this research is to improve our understanding of the effectiveness of surgical OSA treatment by evaluating its impact on these health-related and functional outcomes and comparing these effects to the changes in…
- Trial name
- NCT00518128
- Testing
- Surgical OSA treatment, Positive Airway Pressure Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Sleep Apnea
A Study of VI-0521 for the Treatment of Obstructive Sleep Apnea / Hypopnea Syndrome in Obese Adults
The primary objectives of this study are to evaluate the safety and efficacy of VI-0521 compared to placebo in the treatment of obese adults with obstructive sleep apnea (OSA) and to assess the relative contributions of weight…
- Trial name
- NCT00745251
- Testing
- VI-0521
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- VIVUS LLC