Clinical trials: Sleep Obstructive Apnea
Alzheimer's Disease, Obstructive Sleep Apnea
Sleep in Adults With Down Syndrome and Alzheimer's Disease
RATIONALE of the project. Adults with Down syndrome (DS) present severe sleep disorders that are under recognized by caregivers.
- Conditions
- Alzheimer's Disease, Obstructive Sleep Apnea, Sleep Disturbances
- Trial name
- NCT03942341
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Analgesia, Recovery, Psychological
Enhanced Recovery After Uvulopalatoplasty
Obstructive sleep apnea is a prevalent condition often treated surgically with palatoplasty, which improves airway patency and reduces apneic events.
- Trial name
- NCT07246694
- Testing
- Glossopharyngeal nerve block, Standard multimodal analgesia
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zagazig University
Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease
The primary purpose of the study is to determine whether lemborexant increases the apnea hypopnea index (AHI) on Day 8 of treatment in adult and elderly participants (adults greater than or equal to [>=] 45 to less than [<] 65…
- Conditions
- Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive, Respiration Disorders
- Trial name
- NCT04647383
- Testing
- Lemborexant 10 mg
- Where
- 11 sites in United States
- Volunteers
- 63 people
- Sponsor
- Eisai Inc.
Obstructive Sleep Apnea
Effects of Mandibular Advancing Device in Obstructive Sleep Apnea
The goal of this clinical trial is to learn if Mandibular advancing devices work to treat obstructive sleep apnea in adults. Selected Participants have a mild or moderate degree of obstructive sleep apnea.The main questions it…
- Trial name
- (MADs) (NCT07003854)
- Testing
- Mandibular advancement device
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Ain Shams University
Endometriosis, Obstructive Sleep Apnea-hypopnea
Assessment of the Occurrence of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) in Women Suffering from Endometriosis
This observational study aims at establishing the proportion of patients suffering from endometriosis and for whom an Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) diagnosis is established.
- Trial name
- ENDOSAS (NCT06060756)
- Testing
- questionnaires completion
- Volunteers
- 80 people
- Sponsor
- Elsan
Metabolism and Nutrition Disorder, Obesity
Effect of Liraglutide in Obese Subjects With Moderate or Severe Obstructive Sleep Apnoea: SCALE™ - Sleep Apnoea
This trial is conducted in North America. The aim of the trial is to investigate the effect of liraglutide in obese subjects with sleep apnoea.
- Conditions
- Metabolism and Nutrition Disorder, Obesity, Obstructive Sleep Apnoea
- Trial name
- NCT01557166
- Testing
- liraglutide
- Where
- 42 sites in United States, Canada
- Volunteers
- 359 people
- Sponsor
- Novo Nordisk A/S
Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS), Postoperative Care
Health Belief Model Nursing for Moderate to Severe OSAHS Post-Surgery
This study aimed to investigate the long-term preventive and therapeutic effects of a health belief model (HBM)-based nursing intervention compared to routine care in patients with moderate to severe Obstructive Sleep…
- Trial name
- NCT07050602
- Testing
- Health Belief Model Nursing Intervention, Routine Care
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Hospital of Hebei Medical University
Obstructive Sleep Apnea of Adult
Endothelial Function in Obstructive Sleep Apnea
Obstructive sleep apnea (OSA), a condition that affects a quarter of the Western adults, triples the risk for cardiovascular diseases and increases all-cause mortality.
- Trial name
- NCT03122639
- Testing
- Atorvastatin 10mg
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Columbia University
Bstructive Sleep Apnea (OSA) and Obesity
A Phase III Study Evaluating the Efficacy and Safety of HRS9531 Injection in Subjects With Obstructive Sleep Apnea (OSA) and Obesity
A Phase III Study Evaluating the Efficacy and Safety of HRS9531 Injection in Subjects with Obstructive Sleep Apnea (OSA) and Obesity
- Trial name
- NCT06974851
- Testing
- HRS9531
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
OSA
OSA Recurrence in CPAP Withdrawal
Continuous positive airway pressure (CPAP) therapy is the most effective Treatment for obstructive sleep apnoea (OSA ). However, adherence to CPAP is often limited.
- Trial name
- NCT03472612
- Testing
- CPAP withdrawal
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Stroke, Sleep Apnea, Obstructive
Stroke and CPAP Outcome Study: A Sham-controlled Trial of CPAP Among Stroke Rehabilitation Patients
The purpose of this study is to assess the effect of continuous positive airway pressure (CPAP) on functional outcome in patients with acute stroke, the investigators conducted a sham-controlled, double-blind pilot trial during…
- Trial name
- SCOUTS (NCT02551757)
- Testing
- Auto-titrating CPAP
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Obstructive Sleep Apnea, Sleep-Disordered Breathing
Tongue Morphology and Posterior Airway Space as Predictors of Response in Patientswith Hypoglossal Nerve Stimulation Therapy
Hypoglossal nerve stimulation (HNS) plays an increasingly important role in managing patients with obstructive sleep apnea (OSA) who do not tolerate CPAP therapy and are not eligible for other alternative treatment options, such…
- Trial name
- NCT06154577
- Testing
- Ultrasonography
- Where
- 2 sites in Switzerland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital, Baselland
Hypertension (HTN), Sleep Apnea Syndrome, Obstructive
A Cohort Study on Increasing Blood Pressure Benefits in Sleep Apnea Patients After CPAP Treatment
Research Title "Quadruple-Blind Randomized Controlled Trial of the Effect of CPAP on Blood Pressure in Patients with Sleep Apnea" Why are we conducting this study? Sleep apnea (OSA) is very common, affecting approximately one in…
- Trial name
- NCT07357272
- Testing
- continuous positive airway pressure
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Obstructive Sleep Apnea
Severe Label Expansion for EVO Products Trial
Title: Severe Label Expansion for EVO Positioner (SLEEP) Study Description: Single-arm study to determine the safety and effectiveness of treating severe obstructive sleep apnea using the EVO Sleep and Snore Device (ProSomnus…
- Trial name
- SLEEP (NCT07090395)
- Testing
- EVO Sleep and Snore Device
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- ProSomnus Sleep Technologies
Obstructive Sleep Apnea Risk Management, Postoperative Complications
OSA Risk Level in Dental Patients and Correlation With Complications After General Anesthesia
Obstructive sleep apnea (OSA) is a sleep-related respiratory dysfunction. The prevalence of OSA is increasing with the increasing rates of obesity and elderly population worldwide.
- Conditions
- Obstructive Sleep Apnea Risk Management, Postoperative Complications, Dental Caries Under General Anesthesia, Obstructive Sleep Apnea of Adult
- Trial name
- NCT06430957
- Testing
- The STOP-BANG questionnaire for determining OSA risk level., ASA recommended criteria for determining OSA risk level., Record of postoperative complications
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Kırıkkale University
Sleep Apnea, Obstructive, Snoring
Different Forms of OMT as Methods for Reducing Snoring and Mild to Moderate Sleep Apnea
Objective the present project aims to assess the impact of 1) oral screen training, group training, and the use of neuromuscular electrical training (NMES) as orofacial myofunctional therapy (OMT) methods for reducing the…
- Trial name
- SNORT (NCT06330116)
- Testing
- IQoro, eXciteosa, Grouptraining
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 141 people
- Sponsor
- Region Västerbotten
Obstructive Sleep Apnea
Implant Supported Oral Appliance Treatment of OSA
Mandibular advancing oral appliances (OAm) are an effective and increasingly common treatment modality for the management of obstructive sleep apnea (OSA) in adults.
- Trial name
- BIMA (NCT03362671)
- Testing
- Implant Supported Mandibular Advancement Oral Appliance, Orthodontic Mini Implant
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of British Columbia
Obstructive Sleep Apnea, Sleep-disordered Breathing
Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a common condition in which the airway repeatedly collapses during sleep, leading to poor sleep quality and reduced oxygen levels.
- Trial name
- NCT07577661
- Testing
- Combination device and drug: Unilateral hypoglossal nerve stimulation & atomoxetine-plus-oxybutynin (HGNS+AtoOxy), Unilateral hypoglossal nerve stimulation (HGNS), active comparator condition, Atomoxetine-plus-oxybutynin (80/5 mg) (AtoOxy), active comparator condition
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brigham and Women's Hospital
Sleep Apnea/Hypopnea Syndrome
Automatic Estimation of the Apnea-hypopnea Index Using Neural Networks to Detect Sleep Apnea
The sleep apnea hypopnea syndrome (SAHS) is a respiratory disorder characterized by frequent breathing cessations (apneas) or partial collapses (hypopneas) during sleep.
- Trial name
- NCT02143297
- Where
- Spain
- Volunteers
- 322 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Respiratory Muscle Paralysis
Respiratory Muscle Strength and Function in Neuromuscular Disorders and Chronic Obstructive Pulmonary Disease
Using an extensive set of both volitional and non-volitional tests of respiratory muscle function and strength it is the aim of this study to identify disease-specific patterns of respiratory muscle impairment in different NMD…
- Trial name
- NCT03032562
- Testing
- Multimodal measurement of respiratory muscle function and strength
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Universität Münster
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