Clinical trials: Sleep Problem, open to volunteers
Airway Inflammation, Chronic Obstructive Pulmonary Disease (COPD)
Immune Status and Disease Control of Inflammatory Airway Diseases
The goal of this study is to learn how the body's immune system affects disease control in people with different airway inflammatory diseases.We want to understand: 1.Whether specific immune cell patterns in the blood are linked…
- Conditions
- Airway Inflammation, Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis), Bronchiectasis
- Trial name
- ISDC-IAD (NCT07493629)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Diabetic Neuropathy
Effect of Reiki on Neuropathic Pain Severity and Sleep Quality in Patients With Diabetic Neuropathy
The study is planned to be conducted in a mixed research design with quantitative and qualitative types. The quantitative phase of the study was planned as a single-blind, randomized controlled study with Reiki group, Sham Reiki…
- Trial name
- NCT06668623
- Testing
- Reiki Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Smoking, Nicotine
Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking
Tobacco use is the leading cause of preventable death in the U.S., with 480,000 deaths per year and 7.7 million deaths globally.
- Conditions
- Smoking, Nicotine, Tobacco, Addiction
- Trial name
- NCT07328594
- Testing
- Daridorexant 50 mg
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Legacy Health System
Sleep Disturbance
Sleep Disturbances and Delirium
Delirium is a frequent and serious problem in hospitalized patients; it is associated with multiple hospital-acquired complications.
- Trial name
- SLEEP (NCT05402280)
- Testing
- Sleep protocol
- Where
- Czechia
- Volunteers
- 3,240 people
- Sponsor
- University of Ostrava
ICU, Sleep Deprivation
Evolution of Sleep in Intensive Care Unit Patients
Sleep plays a key role in immune, metabolic, and neurological regulation, particularly in critically ill patients. However, the intensive care environment significantly disrupts sleep due to noise, light exposure, and frequent…
- Trial name
- SOMNOREA (NCT07867912)
- Testing
- Sleep monitoring using Sleepscan®, Actigraphy
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Musculoskeletal Diseases, Depression
Physical Activity Levels and Musculoskeletal Health Among Health Science Academicians at Istanbul Aydin University
This study aims to investigate the relationship between physical activity levels and posture, sleep quality, depression, and musculoskeletal system problems among academic staff working in the health sciences field at Istanbul…
- Conditions
- Musculoskeletal Diseases, Depression, Sleep Wake Disorders, Posture
- Trial name
- PA-ACAD-IAU (NCT07445100)
- Testing
- Observational Data Collection
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Obstructive Sleep Apnea (OSA), Sleep Apnea - Obstructive
Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea (OASIS)
The objective of this study is to evaluate the safety and effectiveness of the Cryosa System when used as intended to perform the Cryosa Procedure.
- Conditions
- Obstructive Sleep Apnea (OSA), Sleep Apnea - Obstructive, OSA
- Trial name
- (OASIS) (NCT07720219)
- Testing
- Cryosa Procedure
- Volunteers
- 130 people
- Sponsor
- Cryosa, Inc.
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Chronic Insomnia, Chronic Pain
Lemborexant vs Clonidine vs Sedatives to Treat Insomnia in Chronic Pain Patients
Prospective observational crossover study of 250 adults undergoing chronic pain management. For insomnia treatment, patients alternate their usual prescribed sedative versus Lemborexant or Clonidine; on alternate nights.
- Conditions
- Chronic Insomnia, Chronic Pain, Restless Leg Syndrome (RLS), Substance Abuse
- Trial name
- NCT05618002
- Testing
- Lemborexant
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Salem Anaesthesia Pain Clinic
Eveningness, Insomnia
Digital Insomnia and Circadian Therapy for Reducing Depression Symptoms in College Students
Depression is a leading cause of global disease burden, poor quality of life, disability and suicide, and commonly occurs in adolescence and early adulthood.
- Conditions
- Eveningness, Insomnia, Circadian Rhythm, Depressed Mood
- Trial name
- NCT07677930
- Testing
- digital cognitive behavioral therapy for insomnia and digital circadian intervention, digital cognitive behavioral therapy for insomnia, digital health education
- Volunteers
- 195 people
- Sponsor
- Chinese University of Hong Kong
Frailty, Sleep Quality
Acupoint Stimulation and Exercise for Taiwanese Pre-frail Older Adults
This study aims to explore the relationships between frailty, daily physical activity, sleep quality, and Traditional Chinese Medicine (TCM) constitutions among older adults in Taiwan.
- Conditions
- Frailty, Sleep Quality, Aging
- Trial name
- NCT07732530
- Testing
- Vivifrail Exercise Program, Acupoint Stimulation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Tainan Hospital, Ministry of Health and Welfare
Menopause
Effect of Laughter Yoga on Menopausal Symptoms, Sleep, and Quality of Life in Menopausal Women
This study aims to provide meaningful contributions to both academic literature and clinical nursing practice by examining laughter yoga, a non-pharmacological, evidence-based, and feasible intervention for quality of life and…
- Trial name
- NCT07435545
- Testing
- Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Strength Training Adaptations, Stress
The Impact of 12-week Ashwagandha Supplementation Induced by Resistance Training on Strength, Levels of Neurotrophic and Stress Response Proteins, Oxidative and Psychological Stress, and Cognitive Function in Physically Active Male Adults
This clinical trial will study the effects of Ashwagandha (Withania somnifera), a natural plant extract, on physical and mental health in adult men.
- Conditions
- Strength Training Adaptations, Stress, Sleep Quality, Cognitive Functions
- Trial name
- NCT07803068
- Testing
- Ashwagandha, Resistance training
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Sleep, Postpartum Depression
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Insufficient and disrupted sleep are rarely addressed in expectant and new mothers, despite evidence that disturbed sleep is a modifiable risk factor for negative health outcomes for mothers and their children.
- Conditions
- Sleep, Postpartum Depression, Pregnancy Related, Insomnia
- Trial name
- NCT06737055
- Testing
- Education about behavioral strategies to improve sleep
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Unipolar Depression, Bipolar Disorder
Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression
Depressed mood is the main symptom of depression, but other symptoms like cognitive impairment, anhedonia or sleep disorders may also contribute to patients suffering and are difficult to treat.
- Trial name
- NCT06363981
- Testing
- Active rTMS over the left DLPFC and over the left DMPFC, Active rTMS over the left DLPFC
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Jakub Antczak
Dry Eye Disease (DED)
Correlation of Dry Eye Disease, Problematic Smartphone Use and Sleep Quality in Adolescents and Young Adults
The goal of this observational study is to learn about the status quo and relationship of dry eye, problematic smartphone use, bedtime procrastination, and sleep in adolescents and young adults.
- Trial name
- NCT07020871
- Where
- China
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Post Traumatic Stress Disorder, Obstructive Sleep Apnea
OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit
Substance use disorder (SUD) and posttraumatic stress disorder (PTSD) frequently co-occur and having both disorders is associated with greater psychological and functional impairment than having either disorder alone.
- Conditions
- Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program
- Trial name
- NCT05156112
- Testing
- Positive Airway Pressure Device
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- VA Office of Research and Development
Opioids, Obstructive Sleep Apnea (OSA)
Impacts of Opioids on Respiratory Drive During Sleep
The investigators are studying the impact that opioids have on breathing during sleep in healthy participants and those diagnosed with obstructive sleep apnea.
- Trial name
- OIRD (NCT06854211)
- Testing
- Morphine p.o.
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Sleep Quality, Mental Health
Effect of a Sleep Hygiene-based Intervention on Sleep Quality and Mental Health in Medical Students
The aim of the study is to investigate whether an online sleep hygiene programm is as effective as a face-to-face programm in improving sleep quality and mental health in medical students.
- Conditions
- Sleep Quality, Mental Health, Students, Medical
- Trial name
- NCT07043530
- Testing
- In-person sleep hygiene-based intervention, Online sleep hygiene-based intervention
- Where
- Mexico
- Volunteers
- 78 people
- Sponsor
- Universidad Autónoma de Yucatán
Insomnia
A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)
People with opioid use disorder (OUD) can have trouble falling or staying asleep. Researchers want to know if suvorexant will help people with OUD fall asleep and stay asleep.
- Trial name
- NCT06655883
- Testing
- Suvorexant
- Where
- 13 sites in United States
- Volunteers
- 300 people
- Sponsor
- Merck Sharp & Dohme LLC
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