Clinical trials: Sleep Problem, open to volunteers
Insomnia, Dementia
Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial
Insomnia is a highly common, chronic disorder that is distressful for the patient but also for caregivers and can give rise to a heavy burden on the healthcare team.
- Conditions
- Insomnia, Dementia, Frontotemporal Dementia
- Trial name
- NCT06093126
- Testing
- Lemborexant 5 MG
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Nova Scotia Health Authority
Chronic Insomnia
Effects of Cognitive Correction and Stimulus Control in Chronic Insomnia Patients
This study aims to validate the effect of cognitive correction and stimulus control on correcting sleep cognitive distortions and improving maladaptive sleep behaviors.
- Trial name
- NCT06658158
- Testing
- Cognitive correction and stimulus control, Sleep hygiene education
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xuanwu Hospital, Beijing
Obstructive Sleep Apnea (OSA)
DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.
The goal of this randomized, double-blind, multi-dose crossover clinical trial is to determine the safety and efficacy of IHL-42X in subjects with obstructive sleep apnea.
- Trial name
- DReAMzz (NCT07635563)
- Testing
- IHL-42X: 2.5 mg dronabinol + 125 mg acetazolamide, IHL-42X: 5 mg dronabinol + 125 mg acetazolamide, IHL-42X: 7.5 mg dronabinol + 125 mg acetazolamide
- Where
- 13 sites in United States
- Volunteers
- 120 people
- Sponsor
- Incannex Healthcare Ltd
Stress, Anxiety
Effect of Ear Massage on Stress, Anxiety, and Sleep Quality in Parents of Children With Type 1 Diabetes
The purpose of this clinical trial is to determine the effect of self-administered ear massage on stress, anxiety levels, and sleep quality in parents of children diagnosed with Type 1 diabetes.
- Conditions
- Stress, Anxiety, Sleep Quality
- Trial name
- NCT06829251
- Testing
- Effective Ear Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Mersin University
Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Interoceptive Awareness
Interoception and Symptom Perception in Acute COPD Exacerbation
Interoception refers to the process of perceiving and interpreting internal physiological signals and plays a central role in symptom perception.
- Trial name
- NCT07719231
- Testing
- No Intervention: Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Insomnia Chronic
Efficacy of Synchronous, Virtual Cognitive Behavioral Therapy for Insomnia Across Phases of Cancer Survivorship
This project is a single center, prospective randomized controlled trial (N=198) primarily evaluating the efficacy of the Survivorship Sleep Program vs. Enhanced Usual Care on insomnia severity among cancer survivors.
- Trial name
- NCT06807086
- Testing
- Cognitive Behavioral Therapy - Insomnia, Enhanced Usual Care
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Massachusetts General Hospital
Insomnia, Insomnia (Moderate)
ASV Therapy for Insomnia
This will be a single center, prospective study designed to evaluate the effect of adaptive servo ventilation therapy on insomnia severity among patients with moderate to severe chronic insomnia.
- Trial name
- NCT07011966
- Testing
- ASV therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- ResMed
Idiopathic Hypersomnia
Efficacy and Tolerance of Solriamfetol in Patients Affected with Idiopathic Hypersomnia.
This Phase II clinical trial is a monocenter, double-blind, randomized, placebo-controlled study aimed at evaluate the efficacy and safety of solriamfetol from 75 to 300 mg per day in IH patients.
- Trial name
- SOLR-IH (NCT06590662)
- Testing
- Solriamfetol
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Insufficient Sleep, Hypertension
Sleep Promotion and Pediatric Hypertension
Determine the effectiveness and feasibility of a mobile health sleep extension approach in the pediatric nephrology setting, to increase sleep duration and reduce systolic and diastolic blood pressure.
- Trial name
- NCT06642246
- Testing
- Intervention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Sleep Wake Disorders, Sleep Initiation and Maintenance Disorders
AI-Powered Sleep Hygiene Mentor for Adults Living With HIV
Poor sleep is common among people living with HIV and is linked to fatigue, psychological distress and poorer adherence to antiretroviral therapy.
- Conditions
- Sleep Wake Disorders, Sleep Initiation and Maintenance Disorders, HIV Infections
- Trial name
- NCT07894042
- Testing
- AI-powered sleep hygiene mentor
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Indonesia
Parkinson Disease (PD), Sleep Initiation and Maintenance Disorders
Lemborexant on Perioperative Sleep Quality in Patients With Parkinson's Disease Undergoing Deep Brain Stimulation
This study tests whether lemborexant, an approved sleep medicine, can improve sleep and recovery in people with Parkinson's disease undergoing deep brain stimulation (DBS) surgery.
- Conditions
- Parkinson Disease (PD), Sleep Initiation and Maintenance Disorders, Deep Brain Stimulation
- Trial name
- NCT07903038
- Testing
- Lemborexant 5 mg, Placabo
- Volunteers
- 128 people
- Sponsor
- Beijing Tiantan Hospital
Opioid Use Disorder, Sleep Disturbance
Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment
Opioid use disorder (OUD) is a treatable medical illness with three medications FDA approved for treatment. However, persons with OUD report significant sleep disturbance, even when treated with medications for opioid use…
- Trial name
- MOUD (NCT06104280)
- Testing
- Post-Illumination Pupillary Response (PIPR), Polysomnography, Multiple Sleep Latency Test
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obstructive Sleep Apnea, Mild Cognitive Impairment
Sleep Apnea and Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment
Obstructive sleep apnea (OSA) is recurrent episodes of partial or complete obstruction of the upper airway during sleep that causes intermittent hypoxia and sleep fragmentation and leads to cardiometabolic and neurocognitive…
- Conditions
- Obstructive Sleep Apnea, Mild Cognitive Impairment, Subjective Cognitive Impairment
- Trial name
- NCT06089096
- Testing
- Home Sleep Apnea test (HSAT)
- Where
- Hong Kong
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Parkinson's Disease, Sleep Fragmentation
Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)
Parkinson's Disease (PD) is the second most common of the age-related neurodegenerative disorders, affecting over 1,900 adults per 100,000 over the age of 80 in the US.
- Trial name
- NCT05070013
- Testing
- Deep Brain Stimulation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Morbid Obesity, Type2diabetes
Comorbidities Resolution After MGB Surgery and Change in Body Composition
This observational study aims to learn about the correlation between the improving comorbidities associated with obesity after MGB (Mini-Gastric Bypass) surgery and changes in body composition in morbidly obese patients.
- Conditions
- Morbid Obesity, Type2diabetes, Sleep Apnea, Hypothyroidism
- Trial name
- MOGAMBO (NCT06015620)
- Testing
- Mini gastric bypass surgery
- Where
- India
- Volunteers
- 35 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Insomnia, Traumatic Brain Injury
Effects of Nurse-Guided BBTi for Improving Insomnia : in Patients at the Recovery Following Traumatic Brain Injury
nsomnia is a frequent complaint reported by patients with TBI, and exacerbates their ability to return to productive activity, which subsequently elevate related healthcare costs and burden.
- Trial name
- NCT05402761
- Testing
- Nurse-guided BBTi group, Mobile-delivered BBTi group
- Where
- 2 sites in Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Autism Spectrum Disorder
Assessing the Impact of Probiotic Supplementation in Children Diagnosed With Autism Spectrum Disorder: the PROBI-O-TISM Study
Children with autism spectrum disorder (ASD) present with stereotyped behaviors and often with comorbidities including gastrointestinal symptoms and sleep disturbances.
- Trial name
- (PROBI-O-TISM) (NCT06906068)
- Testing
- Three strains of Lactobacillus: L. acidophilus CL1285®, L. casei LBC80R® and L. rhamnosus CLR2®
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Valérie Marcil
Sleep, Sleep Quality
The Effects of a Nutritional Supplement on Sleep Quality
This study is a randomized, double-blind, placebo-controlled study of N=140 adult men and women with sub-clinical sleep issues. This study to assess the effect of a novel dietary supplement on sleep related outcomes.
- Trial name
- NCT07345260
- Testing
- Novel powdered sleep supplement
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Athletic Greens International
Insomnia, Suicidal Ideation
Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior
This study will test the effectiveness of a sleep-related primary suicide prevention program entitled TAILOR (Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior), which includes specific behavior-change…
- Conditions
- Insomnia, Suicidal Ideation, Suicide, Attempted
- Trial name
- TAILOR (NCT05390918)
- Testing
- TAILOR, Enhanced Usual Care
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Jeff Bridge
Obstructive Sleep Apnea Syndrome
Trained Patient Involvement to Promote the Resumption of CPAP in Patients Who Have Discontinued Its Use
The primary objective of this randomized clinical trial is to evaluate the role of patient researchers in promoting the resumption of CPAP therapy in apneic patients who had previously stopped CPAP
- Trial name
- NCT04538274
- Testing
- peer-driven intervention
- Volunteers
- 208 people
- Sponsor
- AGIR à Dom
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