Clinical trials: Sleep Problems, open to volunteers
Substance Abuse, Sleep Disturbances
Exploring Substance Use, Sleep Disturbances and Reward Sensitivity
According to foreign medical studies, substance use is closely related to reward sensitivity and sleep patterns. The purpose of this research is to understand the relationship between these three factors, which will help improve…
- Trial name
- NCT07028346
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Volunteers
- 154 people
- Sponsor
- Kwai Chung Hospital
Delirium - Postoperative, Sleep Problems
Preoperative Sleep Intervention on Postoperative Delirium in School-aged Children Undergoing Congenital Heart Surgery
This is a multicenter, randomized, controlled clinical trial aimed to determine whether preoperative sleep interventions could reduce the incidence of adverse outcomes, such as postoperative delirium, in sleep-disordered…
- Conditions
- Delirium - Postoperative, Sleep Problems, Congenital Heart Disease (CHD)
- Trial name
- NCT06879431
- Testing
- cognitive-behavioral intervention
- Where
- China
- Volunteers
- 544 people
- Sponsor
- Yan Fuxia
Non Restorative Sleep, Sleep Disorder (Disorder)
Sleep Promoting Properties of a Botanical Extract in a Population Complaining From Non-Restorative Sleep (NRS)
The goal of this clinical trial is to evaluate the effect of the Botanical Extract in improving sleep symptoms of nonrestorative sleep (NRS) in healthy adults.
- Trial name
- NCT07085819
- Testing
- Botanical Extract, 125mg, Botanical Extract, 250mg, Botanical Extract, 500mg
- Where
- Ireland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kerry Group P.L.C
Restless Legs Syndrome (RLS)
Intravenous Iron in the Management of Drug-resistant Restless Legs syndromeI
The pathophysiology of restless legs syndrome (RLS) is not well understood: it is thought to involve intracerebral iron deficiency and dopaminergic dysregulation.
- Trial name
- IRON-RLS (NCT07822607)
- Testing
- Ferric Carboxymaltose Injection [Ferinject], Randomization, Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Montpellier
Polycystic Ovarian Syndrome
Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Polycystic Ovarian Syndrome.
The study will be a non-blinded randomized controlled trial, consisting of two groups. Non-probability Convenience sampling will be used to recruit participants who will meet the inclusion criteria.
- Trial name
- NCT07645014
- Testing
- Neurodynamic stretches, myofascial pain release technique Interventions:
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Menopause Syndrome, Sleep Disturbance
Exercise as Medicine: A Non-Pharmacological Approach to Menopausal Symptoms
The aim of this clinical trial is to evaluate the effects of different forms of physical exercise in women experiencing menopausal symptoms.
- Trial name
- NCT07351006
- Testing
- Strength training, Dance-based training
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Linnaeus University
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Cannabis Gummy for the Improvement of Sleep and Quality of Life in Patients With Cancer, Pillow Trial
This clinical trial tests how well a cannabis gummy works in improving sleep and quality of life in patients with cancer. Many people with cancer (about 60%) have trouble sleeping, which can lower their quality of life.
- Trial name
- NCT07658677
- Testing
- Actigraphy, Best Practice, Biospecimen Collection
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Theodore Brasky PhD
Kidney Transplant Recipients, Old Age
Neurocognitive Function Changes With Extended-Release Tacrolimus Among Older Kidney Transplant Recipients
The objective of this randomized controlled study is to assess the neurocognitive outcomes between individuals using immediate-release (IR) tacrolimus (Prograf®) and those who were converted to extended-release tacrolimus…
- Trial name
- Neuro-KTR (NCT06751992)
- Testing
- Conversion to extended-release tacrolimus, Maintenance of immediate-release tacrolimus
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Massachusetts General Hospital
Sleep Quality, Meal Timing
This Trial Examines How Last Meal Composition and Timing Affect Sleep Quality and Circadian Gene Expression Among Medical Residents. Recruitment Not Yet Started; Study Begins Dec 2025 and Ends Dec 2026.
This randomized controlled trial aims to evaluate the effects of last meal composition and timing on sleep quality and circadian gene expression among medical residents in Jordanian hospitals.
- Conditions
- Sleep Quality, Meal Timing, Circadian Rhythm, Medical Residents
- Trial name
- CHRONO-MED (NCT07339592)
- Testing
- High-Carbohydrate Last Meal, High-Protein Last Meal, Balanced Standard Dinner
- Where
- Jordan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Obstructive Sleep Apnea
A Study Of Synthetic THC And Sleep
The purpose of this study is to determine if oral dronabinol prior to sleep can improve CPAP adherence and sleep quality in humans.
- Trial name
- NCT07570953
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Mayo Clinic
Obstructive Sleep Apnea of Adult
A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea
Studies show that sleep apnea increases the risk of cardiovascular disease and is associated with obesity. However, it is unclear how sleep apnea affects fat tissue.
- Trial name
- NCT03307330
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Insomnia
Photobiomodulation for Reducing Sedative-Hypnotic Use:Clinical Trial of a Light-Therapy Device
Background: Insomnia is a prevalent and growing public health issue, with one in three adults affected globally and one in five Taiwanese adults reporting significant sleep disturbances.
- Trial name
- NCT07764107
- Testing
- PBM intervention
- Volunteers
- 60 people
- Sponsor
- National Health Research Institutes, Taiwan
Epilepsy
Effects of Exercise on Functional Performance, BDNF, Executive Functions and Sleep Quality in Children with Epilepsy
According to the definition of the International League for the Control of Epilepsy, a seizure is the emergence of temporary symptoms and/or findings as a result of abnormal, excessive and simultaneous stimulation of neurons in…
- Trial name
- BDNF (NCT06677034)
- Testing
- Exercise
- Volunteers
- 50 people
- Sponsor
- Inonu University
Apnea Syndrome, Apnea, Obstructive
Effect of Hypnosis on Adherence to Continuous Positive Airway Pressure.
The prevalence of sleep-disordered breathing is high, with an apnea-hypopnea index of over 15 per hour found in 49.7% of men and 23.4% of women in the general population (1).
- Trial name
- HypnOSA (NCT06397365)
- Testing
- medical hypnosis
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Solelhac Geoffroy
Obstructive Sleep Apnea (OSA)
IOS Parameters and PAP Titration Pressure in Obstructive Sleep Apnea
This prospective observational study aims to investigate whether impulse oscillometry (IOS)-a non-invasive lung function test-can help predict the specific pressure settings needed for positive airway pressure (PAP) therapy in…
- Trial name
- IOS-PAP (NCT07554430)
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Mustafa Kemal University
Obstructive Sleep Apnea, Sleep-disordered Breathing
Combination Upper-Airway Electrical and Pharmacological Stimulation for Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a common condition in which the airway repeatedly collapses during sleep, leading to poor sleep quality and reduced oxygen levels.
- Trial name
- NCT07577661
- Testing
- Combination device and drug: Unilateral hypoglossal nerve stimulation & atomoxetine-plus-oxybutynin (HGNS+AtoOxy), Unilateral hypoglossal nerve stimulation (HGNS), active comparator condition, Atomoxetine-plus-oxybutynin (80/5 mg) (AtoOxy), active comparator condition
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Brigham and Women's Hospital
Auricular Acupressure 、Nurses、Sleep Quality
Effect of Auricular Acupressure on Sleep Quality in Nurses
The purpose of this study is to explore Effect of Auricular Acupressure on Improving Sleep Quality in Nurses. Adopting a quasi-experimental research design and convenience sampling, nursing staff from a northern medical center…
- Trial name
- NCT06833710
- Testing
- Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Mental Health, Insomnia
Mindfulness for Informal Caregivers
The goal of this single-arm pilot clinical trial is to evaluate whether a group-based mindfulness intervention can improve mental health and sleep among parents who are informal caregivers of children with autism spectrum…
- Trial name
- NCT07496138
- Testing
- Mindfulness
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Insomnia
Model-Driven Individualized Transcranial Direct Current Stimulation for the Treatment of Insomnia Disorders
This study is designed to evaluate the efficacy and to explore the best individualized stimulus paradigm of transcranial Electrical Stimulation for insomnia patients.
- Trial name
- NCT06671457
- Testing
- Active transcranial direct current stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhen Wang
Narcolepsy Type 1 (NT 1)
Extended-release Sodium Oxybate in Children
The main objectives of this study are to determine the treatment preferences of children with narcolepsy type 1 between Extended-release sodium oxybate and Non-extended-release oxybates (Sodium oxybate or a medication with the…
- Trial name
- NCT06809803
- Testing
- Extended-release sodium oxybate, Non-extended-release oxybates
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Stanford University
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