Clinical trials: Sleep Problems, open to volunteers
Obstructive Sleep Apnea
Diurnal Evaluation of OSA Upper Airway Collapsibility and Muscle Responsiveness
In the framework of pathophysiological trait in obstructive sleep apnea (OSA) patients, a simplified method is proposed to measure upper airway (UA) collapsibility and muscle responsiveness during wakefulness.
- Trial name
- Muscle-OSA (NCT06334601)
- Testing
- Tests of upper airway collapsibility and muscle responsiveness.
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Istituto Auxologico Italiano
Postoperative Sleep Disturbance, Thoracoscopic Surgery
Lemborexant on Perioperative Sleep Quality in Patients Undergoing Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is the mainstream minimally invasive procedure in thoracic surgery; However, the high-stress state during the perioperative period and severe postoperative pain often lead to…
- Trial name
- NCT07811401
- Testing
- Lemborexant 5 mg
- Volunteers
- 130 people
- Sponsor
- Beijing Tiantan Hospital
Insomnia
Understanding the Role of the Locus Coeruleus in Insomnia
This research project aims to better understand the neurobiological mechanistic underpinnings of insomnia disorder. The main question is whether cortical hyperarousal in individuals with insomnia disorder, measured by…
- Trial name
- LOCUSleep (NCT07392177)
- Testing
- Dexmedetomidine
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Woolcock Institute of Medical Research
Normal Tension Glaucoma, Obstructive Sleep Apnea
Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness
The purpose of this research study is to learn more about the relationship between Obstructive Sleep Apnea (OSA) and Normal Tension Glaucoma (NTG).
- Trial name
- NCT06023927
- Testing
- Clinical observation, diagnostic testing
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Northwell Health
Perimenopause, Postmenopause
Effect of Lifestyle Intervention on Menopausal Symptoms, Sleep Quality, and Anxiety in Peri- and Postmenopausal Women
Menopause is a biological process characterized by the permanent cessation of menstruation, often accompanied by vasomotor symptoms, sleep disturbances, anxiety, and impaired quality of life.
- Conditions
- Perimenopause, Postmenopause, Menopause
- Trial name
- NCT07860645
- Testing
- Structured Lifestyle Education, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Anorexia Nervosa
Sleep Quality and Biomarkers in Adolescent Girls With Anorexia Nervosa
The purpose of this observational study is to systematically evaluate how a 12-month multimodal psychiatric treatment program affects sleep quality, inflammatory and hormonal biomarkers, eating disorder psychopathology, and…
- Trial name
- NCT07644728
- Testing
- Longitudinal Fasting Blood Sampling for Biomarker Assessment, Multimodal Psychiatric Treatment Program, Home Polysomnography - NOX A1
- Volunteers
- 25 people
- Sponsor
- University of Split, School of Medicine
Insomnia, Digestive Endoscopy
Changes in Etomidate Dosage in Patients With Insomnia Undergoing Intravenous Anesthesia
To compare the dosage requirement of etomidate under intravenous anesthesia between patients with insomnia and those with normal sleep pattern.
- Trial name
- NCT07028177
- Testing
- No interventions, it is a observational study
- Where
- China
- Volunteers
- 840 people
- Sponsor
- Beijing Tiantan Hospital
Insomnia, Healthy Adult
The Impact of Insomnia on Pain Sensitivity and the Trajectory of Exercise-induced Muscular Pain
Sleep is a critical determinant of physiological recovery and pain regulation. Growing evidence suggests that sleep disruption directly heightens central and peripheral pain sensitivity to sensory stimuli (e.g., mechanical…
- Conditions
- Insomnia, Healthy Adult, Musculoskeletal Pain, Pain Sensitivity
- Trial name
- NCT07827664
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Sleep Apnea, Chronic Nasal Congestion
Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea
The addition of intranasal oxymetazoline for two weeks to already instituted optimal doses of intranasal fluticasone propionate will decrease the total number of obstructive apneas and hypopneas per hour of sleep in subjects with…
- Trial name
- NCT02630121
- Testing
- Oxymetazoline Hydrochloride
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of South Florida
Chronic Insomnia Disorder, Chronic Insomnia
A Randomized, Single-Blind Study Evaluating the Efficacy and Cost-Effectiveness of Brief Behavioral Therapy for Chronic Insomnia Patients Under Medication Treatment At Nguyen Trai Hospital, Ho Chi Minh City
Insomnia disorder is considered quite common and is recognized as a risk factor for psychiatric disorders. In industrialized countries, chronic insomnia disorder is estimated to affect about 5-10% of the population, with some…
- Conditions
- Chronic Insomnia Disorder, Chronic Insomnia, BBT-I, CBT-I
- Trial name
- NCT06727916
- Testing
- BBT-I, Non BBT-I
- Volunteers
- 100 people
- Sponsor
- Nguyen Trai Hospital
Primary Dysmenorrhea (PD)
Pelvic Floor and Diaphragmatic Breathing Exercises for Primary Dysmenorrhea
This study investigates whether combining pelvic floor muscle exercises with diaphragmatic breathing exercises can reduce menstrual pain in women with primary dysmenorrhea.
- Trial name
- PFDD (NCT07263516)
- Testing
- Pelvic Floor + Breathing Exercises, Diaphragmatic Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Gelisim University
Restless Leg Syndrome (RLS)
Study on the Efficacy of Spinal Cord Stimulation in Patients With Severe Refractory Primary or Secondary RLS
A Double-Blind Randomized Controlled Crossover Study to compare the short-efficacy of Burst-SCS with Sham Stimulation, in patients with severe to very severe RLS refractory or intolerant to standard available treatments and/or…
- Trial name
- REST-SCS (NCT07571733)
- Testing
- Spinal cord stimulation (SCS)
- Where
- 2 sites in Switzerland
- Volunteers
- 15 people
- Sponsor
- Clinica ARS Medica
Restless Leg Syndrome With Knee OA, Sleep Disorder
Comparative Effectiveness of Myofacial Release vs Cupping Therapy on Quality of Life in Restless Leg Syndrome With Knee O.A.
The aim of this study is to determine effectiveness of Myofascial Release and Cupping Therapy on Quality of Life in Restless Leg Syndrome with knee Osteoarthritis.
- Trial name
- RCT (NCT06918847)
- Testing
- Myofacial release, Dynamic cupping therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Dow University of Health Sciences
Diabetes Type 2
Perioperative Meditation Music Intervention in Patients With Type 2 Diabetes Undergoing Elective Surgery
Patients with type 2 diabetes mellitus undergoing elective surgery are at increased risk of perioperative hyperglycemia, anxiety, and poor sleep quality because of the physiological and psychological stress associated with…
- Trial name
- NCT07770204
- Testing
- Meditation Music Group
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Istanbul Aydın University
Restless Leg Syndrome Due to Uraemia
A Self-Controlled Study on the Treatment of Restless Legs Syndrome in Uremia With Dipyridamole
The purpose of this clinical trial is to determine whether dipyridamole can treat restless legs syndrome in patients with uremia. In addition, the safety of dipyridamole will also be evaluated.
- Trial name
- NCT07199504
- Testing
- Dipyridamole 50mg tid
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yunfeng Xia
Insomnia Chronic, Insomnia
Assessment of Usability and Preliminary Effectiveness of a Digital Sleep Aid in an Italian Sample
Chronic insomnia affects approximately 30% of the Italian population, leading to significant impairments in daily functioning and overall health.
- Trial name
- REST (NCT06926348)
- Testing
- Digital Health Technology for Chronic Insomnia, Treatment as Usual (TAU)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Universita di Verona
Sleep, Sleep Apnea
Research Framework Exploring Sleep Health
This is a digital health study in which participants are recruited to collect sleep and activity data from digital activity trackers.
- Conditions
- Sleep, Sleep Apnea, Obesity, Mood
- Trial name
- REFRESH (NCT05197738)
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Obstructive Sleep Apnea
Superimposition of Intra-oral Scans in MAD Therapy for OSA
Obstructive Sleep Apnea (OSA) affects quality of life and health. Mandibular Advancement Devices (MAD) can help with OSA but may cause dental and jaw changes.
- Trial name
- SIMT-OSA (NCT06612008)
- Testing
- Mandibular Advancement Device
- Volunteers
- 250 people
- Sponsor
- Amsterdam UMC, location VUmc
Psoriasis Arthritis, SAPHO Syndrome
Typological Study of Sleep Pathologies During Psoriatic Rheumatism and SAPHO Syndrome: Prospective Study Within the Paris Saint-Joseph Hospital Group"
Chronic inflammatory rheumatisms (CIR) are a source of motor disability and various comorbidities, particularly cardiovascular and metabolic. They also significantly impact patients' quality of life, including sleep disturbances.
- Conditions
- Psoriasis Arthritis, SAPHO Syndrome, Sleep Apnea Syndromes
- Trial name
- SleepSO2 (NCT07086599)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Multiple Sclerosis, Caregiver Burden
Multiple Sclerosis Severity and Caregiver Health Outcomes
This cross-sectional observational study aims to investigate the associations between multiple sclerosis (MS) severity and caregivers' sleep quality, physical activity, body awareness, perceived stress, and caregiver burden.
- Conditions
- Multiple Sclerosis, Caregiver Burden, Sleep Quality, Physical Activity
- Trial name
- NCT07842744
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Süleyman Korkusuz
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