Clinical trials: Sleep Problems, open to volunteers
Sleep Quality, Cognitive Function
Effects of Walking Exercise on Sleep Quality in Older Adults
This study aims to explore whether increasing physical activity can improve sleep quality in older adults, particularly those with poor sleep, and whether such improvements positively influence cognitive functions such as memory…
- Trial name
- NCT07027176
- Testing
- walking exercise
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yea-Ru Yang
Insomnia
Examining the Effectiveness of Two Behavioral Interventions for Sleep Problems in Infants
Behavioral insomnia of childhood affects 15-30% of infants. Behavioral interventions, based on limiting parent-child bedtime and nighttime interactions, are effective in significantly improving infant sleep problems.
- Trial name
- NCT05726890
- Testing
- bedtime intervention for early childhood insomnia, bedtime and nighttime intervention for early childhood insomnia
- Where
- Israel
- Volunteers
- 270 people
- Sponsor
- Ben-Gurion University of the Negev
Knee Osteoarthritis, Insomnia
Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis
This research will compare the effectiveness of a remotely delivered personalized exercise coaching plus an evidence-based sleep improvement intervention to remotely delivered personalized exercise coaching alone for knee…
- Trial name
- NCT06580561
- Testing
- Personalized exercise coaching, Cognitive behavioral therapy for Insomnia
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- University of Michigan
Insomnia Disorders, Insomnia Disorder
Comparative Efficacy of BRT and CBT-I for Insomnia
This study evaluates two behavioral treatments for patients with insomnia disorder: Bedtime Restriction Therapy (BRT) and Cognitive Behavioral Therapy for Insomnia (CBT-I).
- Conditions
- Insomnia Disorders, Insomnia Disorder, Insomnia, Insomnia Chronic
- Trial name
- SLEEPwindow (NCT06767137)
- Testing
- Cognitive behavioral therapy for insomnia (CBT-I), Bedtime restriction (BRT)
- Where
- 2 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Christoph Nissen
Sleep Architecture, Mild Traumatic Brain Injury
Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)
This study will employ cognitive behavioral therapy for insomnia (CBT-I) among individuals with mild traumatic brain injury (mTBI) who experience sleep disturbances.
- Conditions
- Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
- Trial name
- NCT07385105
- Testing
- Cognitive behavioral Therapy for insomnia (CBT-I)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Minor, Scoliosis; Juvenile
Evaluation of a Prehabilitation Program in Patients Requiring Scoliosis Surgery.
Scoliosis is a curvature of the spine that, in the most severe cases, may require surgical treatment. This surgery is invasive and complex, causing anxiety for children, adolescents, and their parents.
- Conditions
- Minor, Scoliosis; Juvenile, Scoliosis; Adolescence, Surgery
- Trial name
- PHYPSYSCOL (NCT07852286)
- Testing
- Pre-habilitation program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Menopausal Women, Insomnia
Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms
The goal of this clinical trial is to learn how three current insomnia therapies (trazodone, daridorexant, cognitive behavioral therapy for insomnia) compare with each other in peri- and post-menopausal women.
- Trial name
- CELESTE (NCT07136415)
- Testing
- Cognitive behavioral therapy for insomnia (CBT-i), Trazodone, Daridorexant
- Where
- 5 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Brigham and Women's Hospital
Insomnia
Clinical Observation of Facial Acupuncture for Insomnia
Insomnia is one of the most common mental disorders and has shown an upward trend in recent years. The commonly used western medicine treatment methods are easy produce drug-related adverse reactions, and there are problems such…
- Trial name
- NCT07381647
- Testing
- facial acupuncture, facial scraping
- Volunteers
- 82 people
- Sponsor
- Pei Yuan
Sleep Quality, Menopause
Effect of ZenRest™ Lotus Seed & Rice Germ Extract Blend on Sleep Quality in Menopausal Women
The goal of this clinical trial is to learn if ZenRest™ (Lotus Seed \& Rice Germ Extract Blend) can help improve sleep quality in menopausal women aged 40-65 with mild-to-moderate sleep complaints.
- Trial name
- NCT07678359
- Testing
- Lotus Seed & Rice Germ Extract
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea
Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention
The investigators will conduct a Type I hybrid effectiveness-implementation study to test an integrated telehealth intervention among 400 overweight and obese patients with Chronic Obstructive Pulmonary Disease (COPD) and…
- Conditions
- Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea, Overweight and Obesity
- Trial name
- FOCuSEd (NCT06390345)
- Testing
- FOCuSEd Integrated Intervention, Enhanced Usual Care
- Where
- 5 sites in United States
- Volunteers
- 400 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Obstructive Sleep Apnea
Comparative Assessment of Sleep Positive Airway Pressure Modalities (CASPAM)
Obstructive sleep apnea (OSA) has been one of the topmost global health problems. It is an underdiagnosed disease which have a huge burden on healthcare if left untreated.
- Trial name
- CASPAM (NCT06564896)
- Testing
- CPAP Airsense 10 vs Air-Mini
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- National University of Malaysia
Asthma (Diagnosis), OSA - Obstructive Sleep Apnea
Obstructive Sleep Apnoea and Difficult Asthma (OSADA)
The OSADA (Obstructive Sleep Apnoea in Difficult Asthma) trial is an open-label, randomized control trial investigating the impact of diagnosing and treating obstructive sleep apnoea (OSA) on a asthma control in patients with…
- Conditions
- Asthma (Diagnosis), OSA - Obstructive Sleep Apnea, CPAP Treatment
- Trial name
- OSADA (NCT07160868)
- Testing
- Continuous positive airway pressure (CPAP)
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- St. James's Hospital, Ireland
Restless Leg Syndrome (RLS), Variant Restless Legs Syndrome
Novel Calcium Channel Modulators in RLS and Variants: Efficacy & Safety
The goal of this [study type: clinical trial] is to [primary purpose: evaluate the efficacy and safety of a novel calcium channel modulator in treating Restless Legs Syndrome (RLS) and its variant subtypes] in [describe…
- Trial name
- NCT07453862
- Testing
- Crisugabalin
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Beijing Friendship Hospital
Sleep Apnea, Obstructive
Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep
This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is…
- Trial name
- Nasal vs Oral (NCT06789770)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
OSAS (Obstructive Sleep Apneas Syndrome), DISE
The Use of Remimazolam Versus Dexmedetomidine for Patients Receiving Drug-Induced Sleep Endoscopy
This study seeks to compare the clinical efficacy and safety of the novel sedative Remimazolam with Dexmedetomidine in Drug-Induced Sleep Endoscopy (DISE), evaluating their performance in sedation depth stability, incidence of…
- Conditions
- OSAS (Obstructive Sleep Apneas Syndrome), DISE, Sedation
- Trial name
- NCT07459322
- Testing
- Remimazolam, Dexmedetomidine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fu Jen Catholic University Hospital
COPD (Chronic Obstructive Pulmonary Disease), Obesity Hypoventilation Syndrome (OHS)
Assessment of Breathing Pattern During NIV
COPD and OHS are respiratory conditions that disrupt normal breathing. Positive airway pressure, specifically Non-Invasive Ventilation (NIV), has been shown to improve breathing and reduce symptoms in patients with these…
- Trial name
- NCT06682286
- Testing
- NIV mask A, NIV mask B
- Where
- New Zealand
- Volunteers
- 40 people
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea
Effectiveness of NOA OATMAD
This study is looking at how well the OrthoApnea NOA appliance, a special custom-made mouthpiece, helps treat people with obstructive sleep apnea (OSA).
- Trial name
- NCT07111962
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Obstructive Sleep Apnea (OSA)
Inspire UAS High Apnea Hypopnea Index (AHI)/High Body Mass Index (BMI) Post-Approval Study
The purpose of this observational clinical study is to provide evaluation of long-term safety and effectiveness in a newly expanded patient population including patients with a higher AHI and a higher BMI.
- Trial name
- AHIBMI PAS (NCT07113288)
- Testing
- Inspire® UAS System
- Where
- 5 sites in United States
- Volunteers
- 70 people
- Sponsor
- Inspire Medical Systems, Inc.
Restless Leg Disorder, Restless Leg Syndrome (RLS)
Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome
The goal of this study is to evaluate whether peroneal electrical nerve stimulation (PNS) using the TOMAC™ device is a feasible, acceptable, and safe non-pharmacologic intervention for managing Restless Legs Syndrome (RLS) during…
- Conditions
- Restless Leg Disorder, Restless Leg Syndrome (RLS), Pregnancy, Sleep Disorder (Disorder)
- Trial name
- PENS-P (NCT07144631)
- Testing
- Peroneal Nerve Stimulation (PNS) Device
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Rhode Island Hospital
Insomnia, Stress
Racism-related Stress and Objective Short-sleep as Moderators of Treatment Effect in Cognitive Behavioral Therapy for Insomnia
The purpose of this study is to understand whether Black participants with insomnia with objective short-sleep (ISSD) experience less symptom improvement in response to Cognitive Behavioral Therapy for Insomnia (CBTi) than…
- Conditions
- Insomnia, Stress, Short Sleep Phenotype, Race
- Trial name
- NCT07445529
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBTi)
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
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