Clinical trials: Sleep Problems, open to volunteers
Obstructive Sleep Apnea, Down Syndrome
Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)
The overall objective of this randomized clinical trial is to test the effectiveness of a personalized approach to the surgical treatment of OSA in children with Down syndrome (DS).The estimated prevalence of obstructive sleep…
- Trial name
- TOPS-DS (NCT05508971)
- Testing
- DISE-Directed Surgery, Adenotonsillectomy
- Where
- 7 sites in United States
- Volunteers
- 304 people
- Sponsor
- Oregon Health and Science University
Histamine, Cowhage
Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity
In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep deprivation on itch: To investigate similarity and differences between itch and pain by comparing the effect of sleep…
- Conditions
- Histamine, Cowhage, Sleep Deprivation
- Trial name
- NCT06081998
- Testing
- Histamine, Cowhage
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Depression, Insomnia
Implementation of Internet-based Psychotherapy for Symptoms of Depression, Insomnia and Anxiety in Primary Care in the Cities of Indaiatuba and Jaguariuna
The main objective of this study is to evaluate the effectiveness and success of implementing internet-based cognitive behavioral psychotherapy (iCBT) guided by a therapist for symptoms of depression, insomnia and anxiety in…
- Conditions
- Depression, Insomnia, Anxiety
- Trial name
- NCT06817109
- Testing
- interactive technological intervention for improvement of mental health symptoms in Primary Care users Health
- Where
- 2 sites in Brazil
- Volunteers
- 268 people
- Sponsor
- University of Sao Paulo General Hospital
Lumbopelvic Pain, Insomnia
Effects of Progressive Muscle Relaxation Exercises During Pregnancy.
Lumbopelvic pain (LPP) during pregnancy is defined as pregnancy-related low back, or pelvic girdle pain. Pregnancy is a significant time for sleep disruptions as well.PMR involves systematically tensing and relaxing different…
- Trial name
- NCT06536764
- Testing
- Progressive Muscle Relaxation Exercises, Conventional Therapy(Hot pack,TENS,Patient Education)
- Where
- Pakistan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Restless Legs Syndrome (RLS)
Optimizing Extended-Duration (XD-) TOMAC Therapy for Restless Legs Syndrome (RLS)
This study assesses the tolerability, safety, and impact of an investigational medical device on restless legs syndrome symptoms. The IRB has established that the investigational device is non-significant risk.
- Trial name
- NCT07675109
- Testing
- Investigational Extended Duration (XD-) TOMAC Therapy, Tonic Motor Activation (TOMAC) Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Noctrix Health, Inc.
Chronic Insomnia
Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR)
In France, the treatment of chronic insomnia relies mainly on hypnotic drugs in routine care, despite the high level of iatrogenicity.
- Trial name
- HypERR (NCT06898099)
- Testing
- "Standard care" control group (without hypnosis), Experimental group: "E2R hypnosis"
- Where
- 35 sites in France
- Volunteers
- 136 people
- Sponsor
- Rennes University Hospital
Autism Spectrum Disorder
Sleep Disturbance in Subjects With Autism Spectrum Disorders (ASD) in Preschool Age (18-60 Months)
An observational study is one that aims to collect data from routine clinical practice, without altering a patient's standard diagnostic and therapeutic pathway (no additional instrumental or laboratory tests beyond those…
- Trial name
- NCT07470138
- Testing
- follow up
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Eugenio Medea
Snoring, Sleep Fragmentation
Improving Sleep Quality During Pregnancy Using an Oral Appliance
Many pregnant women suffer from poor sleep quality and snoring. Evidence shows an increasing association between (1) sleep disordered breathing and (2) maternal cardiovascular disease and in-hospital death.
- Trial name
- PREGNCCT (NCT03646214)
- Testing
- Midline traction oral appliance
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Temporomandibular Disorders (TMD)
Effects of a Biopsychosocial Approach Added to Physiotherapy in Temporomandibular Disorders
Temporomandibular disorders are conditions that affect the jaw joint and surrounding muscles and may cause pain, limited jaw movement, stress, sleep problems, and teeth grinding.
- Trial name
- TMD-BPS (NCT07320144)
- Testing
- Physiotherapy Program, Biopsychosocial Intervention
- Volunteers
- 40 people
- Sponsor
- Betül Özata
Sleep Apnea, Obstructive, Polycythemia
CPAP Effect on the Polycythemia in Patients With Obstructive Sleep Apnea
Objectives: To compare the response of polycythemia in terms of hematocrit decrease in patients treated with positive airway pressure (CPAP) versus patients not treated with CPAP.
- Trial name
- PoliAOS (NCT06089603)
- Testing
- Continuous positive airway pressure, Conventional pharmacological treatment, Sleep ,diet and life style recomendations
- Where
- Spain
- Volunteers
- 182 people
- Sponsor
- Hospital Universitario Ramon y Cajal
Moderate to Severe Insomnia
HALO Clarity™ Cranial Alternating Current Stimulation Therapy for Adults With Moderate-to-Severe Insomnia
A prospective, decentralized, individually-randomized, triple-blind* sham-controlled, superiority trial to evaluate the safety and efficacy of HALO Clarity™ device in reducing insomnia severity.
- Trial name
- NCT07659366
- Testing
- Transcranial alternating current stimulator
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Nexalin Technology
Obstructive Sleep Apnea of Adult
Effect of Inspiratory Muscle Training in Obstructive Sleep Apnea Syndrome.
Sleep apnea-hypopnea syndrome is a sleep-related respiratory disorder characterized by partial or total interruptions in breathing during sleep.
- Trial name
- NOCTURNE (NCT06117579)
- Testing
- Inspiratory muscle training
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Obstructive Sleep Apnea (OSA), Mild Cognitive Impairment
CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial
Obstructive sleep apnea (OSA) is a prevalent condition that significantly impacts the sleep health and overall well-being of millions of adults worldwide.
- Trial name
- CRESCENDO (NCT06983769)
- Testing
- MAD, CPAP
- Where
- Singapore
- Volunteers
- 260 people
- Sponsor
- National University Hospital, Singapore
Critical Illness, Delirium in the Intensive Care Unit
Digital and Plasma Biomarkers in Delirium
The goal of this observational study is to learn if there are potential digital and plasma-based biomarkers that could help detect, predict, and prognosticate delirium in older adult patients who are admitted to the intensive…
- Conditions
- Critical Illness, Delirium in the Intensive Care Unit, Sleep Quality
- Trial name
- DELTA (NCT07694206)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Scripps Health
Critical Illness, Sleep Deprivation
Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle
More than 5 million patients are admitted to the intensive care unit every year in the United States; most of these patients experience profound sleep and circadian disruption.
- Conditions
- Critical Illness, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Unspecified
- Trial name
- ReAlign-ICU (NCT05551325)
- Testing
- Chronobundle - light, chronobundle - feeding, chronobundle - mobility
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Yale University
Loneliness, Fear of Missing Out
Social Media Diet and Psychological Outcomes in University Students
This study aims to examine the effect of a social media diet intervention on loneliness, fear of missing out (FoMO), and sleep quality among university students.
- Conditions
- Loneliness, Fear of Missing Out, Sleep Quality
- Trial name
- The Effect of (NCT07473791)
- Testing
- Social Media Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Apnea, Obstructive Sleep
Associations Apnoea Hypopnoea Index (AHI) and Malocclusions in Growing Patients With Maxillary Constriction
The aim of this prospective clinical study is to evaluate the association between the Apnoea Hypopnoea Index (AHI) and the type of malocclusion in pediatric patients with maxillary constriction.
- Trial name
- NCT07009535
- Testing
- Polysomnography
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Pavia
Insomnia, Chronic Insomnia
Effects of Accelerated rTMS on Sleep Architecture in Chronic Insomnia Disorder
Chronic insomnia disorder is a common condition in which people have ongoing difficulty falling asleep, staying asleep, or waking too early.
- Conditions
- Insomnia, Chronic Insomnia, Chronic Insomnia Disorder, Sleep Disturbance
- Trial name
- NCT07595185
- Testing
- TMS
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- San Francisco Neurology and Sleep Center
Insomnia Disorders, Physical Inactivity
Internet-Based Cognitive Behavioral Therapy and Physical Activity for Insomnia
Internet-based cognitive behavioural therapy for insomnia (iCBT-I) has shown promise for reducing insomnia symptoms. Additionally, physical activity has long been known to contribute to better sleep.
- Trial name
- INSOMNIAC (NCT07794943)
- Testing
- Internet-based cognitive behavioral therapy & physical ACtivity for INSOMNIa (iCBT-I-PA), Behavioral: Internet-based cognitive behavioral therapy & physical ACtivity for INSOMNIa (iCBT-I)
- Where
- Sweden
- Volunteers
- 355 people
- Sponsor
- Uppsala County Council, Sweden
Obstructive Sleep Apnea
Automated vs Manual Polysomnography Scoring in Adults With Obstructive Sleep Apnea
This prospective study aims to compare automated polysomnographic scoring with manual scoring in adult patients with Obstructive Sleep Apnea (OSA).
- Trial name
- NCT07826143
- Testing
- Polysomnographic Scoring (Automated vs. Manual)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
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