Clinical trials: Sleep Problems, open to volunteers
Sleep Apnea
Personalized Obstructive Sleep Apnea Treatment and Effects on Alzheimer's Disease Biomarkers and Cognition Among Blacks
The purpose of this research is to see how effective the Personalized obstructive sleep apnea (OSA) Treatment Adherence Model called PRAISE is in helping the patient stick to the physician recommended OSA treatment plan Positive…
- Trial name
- PRAISE (NCT06089161)
- Testing
- Standard of Care, Personalized OSA Treatment
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of Miami
Chronic Pain, Obstructive Sleep Apnea
Clinical Outcomes of Continuous Positive Airway Pressure Treatment in People With Obstructive Sleep Apnea and Chronic Pain
The bidirectional link between sleep and pain is a widely accepted concept. While there has been much focus on this in recent years, studies investigating obstructive sleep apnoea (OSA) and chronic pain are still not very common…
- Trial name
- NCT06834724
- Testing
- Standard OSA care
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Vrije Universiteit Brussel
Obstructive Sleep Apnea (OSA)
Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Not Treated With Positive Airway Pressure (PAP) Therapy
This study is a multicenter, randomized, double-blind, parallel, placebo-controlled Phase III clinical trial evaluating the efficacy and safety of GZR18 injection in obese subjects with moderate to severe obstructive sleep apnea…
- Trial name
- NCT07493057
- Testing
- GZR18 injection
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Gan & Lee Pharmaceuticals.
Insomnia
A Multicenter Observational Study of Daridorexant in the Treatment of Insomnia
This study aims to evaluate the effectiveness and safety of daridorexant, a novel dual orexin receptor antagonist (DORA), in patients with insomnia.
- Trial name
- NCT07847021
- Testing
- Daridorexant 50 mg
- Where
- 25 sites in China
- Volunteers
- 500 people
- Sponsor
- Shanghai Mental Health Center
Obstructive Sleep Apnea
Orofacial Myofunctional Therapy and Positive Airway Pressure-CPAP Trial for Mild-to-Moderate Obstructive Sleep Apnea
The goal of this clinical trial is to evaluate the isolated and combined effects of orofacial myofunctional therapy (OMT) and continuous positive airway pressure (CPAP) in adults with mild-to-moderate obstructive sleep apnea.
- Trial name
- OMPACT-OSA (NCT07539870)
- Testing
- Orofacial Myofunctional Therapy, Continuous Positive Airway Pressure, Standard of Care Sleep-Hygiene and Lifestyle Counseling
- Volunteers
- 168 people
- Sponsor
- Saint-Joseph University
Breast Neoplasm Malignant Female, Exercise
Step Count and Treatment Response in Neoadjuvant Breast Cancer
This prospective multicenter observational study (NEOBRE-STEP) investigates the impact of daily step counts, measured by Huawei Fit 2 smartwatches, on treatment response in patients with non-metastatic Human Epidermal Growth…
- Conditions
- Breast Neoplasm Malignant Female, Exercise, Breast Cancer Females, Wearable Technology
- Trial name
- NEOBRE-STEP (NCT07162675)
- Testing
- Huawei Fit 2 Smartwatch
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ankara Etlik City Hospital
Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Background: Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever syndrome of childhood.
- Conditions
- Periodic Fever, Aphthous Stomatitis, Pharyngitis, And Cervical Adenitis (Pfapa), Obstructive Sleep Apnea, Tonsillitis, Tonsil Disorder
- Trial name
- NCT05656365
- Where
- 3 sites in United States
- Volunteers
- 1,500 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
OSA - Obstructive Sleep Apnea
Effects of Eszopiclone and Lemborexant in People With OSA With a Low Arousal Threshold Who Have Difficulty Sleeping
Insomnia and obstructive sleep apnoea (OSA) are very common conditions, collectively estimated to affect 2 billion people globally, and share many of the same symptoms.
- Trial name
- ELOSA (NCT06928766)
- Testing
- Eszopiclone 3 mg, Lemborexant 10mg
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Flinders University
Obstructive Sleep Apnea, Pre-diabetes
CPAP and Glucose Metabolism in Non-Diabetic OSA Subjects
The purpose of the current study is to investigate whether alleviation of OSA by CPAP positively impacts glucose metabolism in non-diabetic patients.
- Trial name
- NCT05335083
- Testing
- CPAP
- Where
- 2 sites in Australia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Woolcock Institute of Medical Research
Sleep Disturbance, Cognitive Change
Integrating Systematic Data of Medicine to Explore the Solution for Healthy Aging (ISDHA) Phase 4
This project aims to build up the comprehensive health database of geriatric medicine for middle-aged and elderly people in Taiwan.
- Conditions
- Sleep Disturbance, Cognitive Change, Aging
- Trial name
- NCT07414680
- Where
- 2 sites in Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Vital Sign Evaluation, Vital Sign Monitoring
Effect of ANNE One-Wellue Device Array Use on Staff Bedside Vital Sign Measurement Activity
Randomized controlled trial of a time motion study of time spent obtaining and charting vital signs for inpatients, comparing use of a wireless Bluetooth vital sign array as intervention versus routine vital sign obtainment…
- Conditions
- Vital Sign Evaluation, Vital Sign Monitoring, Sleep Quality, Provider Behavior
- Trial name
- ANNE One TMRCT (NCT06995742)
- Testing
- Device Array Use, Routine Vital Sign Measurement
- Where
- 2 sites in United States
- Volunteers
- 270 people
- Sponsor
- Northwestern University
Sleep Quality and Psychological Well- Being
The Effect of Meditation Applied to Elderly Individulas on Sleep Quality and Psychological Well- Being
It is planned as a randomized controlled experimental study to examine the effect of theta healing meditation technique on sleep quality and psychological well- being of elderly individuals.
- Trial name
- Meditation (NCT06746987)
- Testing
- Meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mersin University
Chronic Insomnia
Effects of Cognitive Correction and Stimulus Control in Chronic Insomnia Patients
This study aims to validate the effect of cognitive correction and stimulus control on correcting sleep cognitive distortions and improving maladaptive sleep behaviors.
- Trial name
- NCT06658158
- Testing
- Cognitive correction and stimulus control, Sleep hygiene education
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xuanwu Hospital, Beijing
Obstructive Sleep Apnea
Head to Head Comparison of Upper Airway Stimulation and Continuous Positive Airway Pressure; a Pilot Study.
To date, there has been no head to head comparison of Upper Airway Stimulation (UAS) and Continuous Positive Airway Pressure (CPAP) utilizing a full night polysomnographic evaluation.
- Trial name
- NCT04191512
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Insomnia, Health Adult Subjects
Does Style Matter: Comparison of Moderate- to Low-intensity Styles of Yoga
The goal of this clinical trial is to learn if yoga works to improve sleep and heart health in adults with and without insomnia disorder.
- Conditions
- Insomnia, Health Adult Subjects, Insomnia Disorder, Heart Health Markers
- Trial name
- NCT07638267
- Testing
- Vinyasa yoga, Gentle yoga, Non-active control
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Caitlin Cheruka
Obstructive Apnea, Sleep Apnea Syndrome, Obstructive
Pilot Study of Negative Pressure Neck Therapy (NPNT)
Obstructive sleep apnea (OSA) is a serious, chronic sleep-related breathing disease in which the upper airway repeatedly collapses during sleep, leading to intermittent oxygen deprivation.
- Conditions
- Obstructive Apnea, Sleep Apnea Syndrome, Obstructive, Sleep Disorder (Disorder)
- Trial name
- NCT07301567
- Testing
- Negative Pressure Neck Therapy (NPNT)
- Where
- 2 sites in Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Insomnia
Evaluation of Digital Sleep Program to Improve Sleep Among New Parents
Sleep disturbances are highly prevalent during the postpartum period, with an estimated 40-60% of new parents experiencing inadequate sleep.
- Trial name
- NCT07302893
- Testing
- Digital CBT-I
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Udisense DBA Nanit
Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI)
Study of Bedroom Environment Sleep Intervention at Home for Older Adults Living Alone With Memory Concerns
This is an eight-week pilot research study designed to test whether simple changes to the bedroom environment along with brief sleep hygiene strategies, can improve sleep in older adults who live alone, have memory concerns, and…
- Conditions
- Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), Insomnia
- Trial name
- NCT07440498
- Testing
- Bedroom Environment Tailoring, Sleep Health Education
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Restless Leg Syndrome (RLS)
Observe Change in Nasal Swab DRD2 Gene Expression in Restless Legs Syndrome (RLS) Patients on Prolonged Dopamine Agonist Treatment
The study aims to observe changes in dopaminergic genes expression in peripheral tissue upon prolonged dopamine agonist treatment on patients with Restless Legs Syndrome (RLS).
- Trial name
- RLS-DRD2gene (NCT06726785)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- HBC Immunology Inc
Sleep Deprivation, Menstrual Cycle
The Effects of Night Shift Work on Health Across the Menstrual Cycle
The study aims to investigate the effects of sleep deprivation on women's health across different phases of the menstrual cycle.
- Conditions
- Sleep Deprivation, Menstrual Cycle, Brain Health, Metabolism
- Trial name
- MENSLEEP (NCT06683248)
- Testing
- Investigate sleep deprivation
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.