Clinical trials: Sleep Problems, open to volunteers
Knee Osteoarthritis
Effect of Combined Quadriceps and Calf Strengthening Program on Gait in Knee Osteoarthritis Patients
The aim of this study is to determine the effects of a combined quadriceps and calf strengthening program on gait, strength, pain, disability, functional mobility, and sleep quality in patients with knee osteoarthritis.
- Trial name
- NCT07402447
- Testing
- Group A (Combined Quadriceps and Calf Strengthening), Group B( Conventional)
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Transient Global Amnesia
PRevalence Of Transient Global Amnesia in Obstructive Sleep Apnea Syndrome
Amnesic stroke is an amnestic syndrome lasting less than 24 hours characterized by the occurrence of anterograde amnesia often associated with retrograde amnesia, the pathophysiology of which is still poorly understood at…
- Trial name
- PROTOS (NCT06903026)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Strasbourg, France
Delayed Sleep-Wake Phase Disorder, Sleep Disorder
Sleep in Psychiatric Care (SIP): Treatment for Comorbid Delayed Sleep-Wake Phase Disorder (DSWPD)
Sleep disorders commonly co-occur with psychiatric disorders. Sleep disorders are often treated with medication or not at all in psychiatric care, although there exist a plethora of documentation of the effectiveness of sleep…
- Conditions
- Delayed Sleep-Wake Phase Disorder, Sleep Disorder, Psychiatric Disorder
- Trial name
- SIP (NCT05177055)
- Testing
- Group-based light therapy at gradually advanced timing for DSWPD, Group-based light therapy at gradually advanced timing for DSWPD and additive bb-glasses, 6-week wait list for sleep-school
- Where
- 2 sites in Norway
- Volunteers
- 60 people
- Sponsor
- Haukeland University Hospital
Insomnia Chronic, Insomnia
Assessment of Usability and Preliminary Effectiveness of a Digital Sleep Aid in an Italian Sample
Chronic insomnia affects approximately 30% of the Italian population, leading to significant impairments in daily functioning and overall health.
- Trial name
- REST (NCT06926348)
- Testing
- Digital Health Technology for Chronic Insomnia, Treatment as Usual (TAU)
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Universita di Verona
Insomnia, Sleep
Artificial Intelligence (AI)-Assisted Sleep Intervention for Insomnia in Older Adults With Subjective Cognitive Decline
To assess the feasibility and acceptability of Artificial Intelligence (AI)-assisted sleep intervention on improving the insomnia of older adults with subjective cognitive decline.
- Trial name
- NCT07588035
- Testing
- Artificial Intelligence (AI)-assisted sleep intervention, Usual Care
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting
The Effect of White and Pink Noise in Patients Undergoing Total Hip and Knee Arthroplasty
This study aims to investigate the effects of preoperative white noise and pink noise interventions on sleep quality, anxiety, postoperative pain, nausea, and physiological parameters in patients undergoing elective total hip…
- Conditions
- Arthroplasty, Replacement, Knee, Hip, Postoperative Nausea and Vomiting, Anxiety, Postoperative Pain After Arthroscopic Knee Surgery
- Trial name
- NCT07858058
- Testing
- White Noise Intervention, Pink Noise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Ataturk University
Psychological Stress, Sleep Disturbance
Sleep More, Stress Less: 90-Day Trial of Neuralli Mood
This decentralized, single-arm study evaluates the effects of 90 days of daily Neuralli Mood supplementation on perceived stress, sleep disturbance, mood, anxiety, depressive symptoms, happiness, and occupational burnout in…
- Conditions
- Psychological Stress, Sleep Disturbance, Anxiety Symptoms, Depressive Symptoms
- Trial name
- NM90 (NCT07717385)
- Testing
- Neuralli Mood
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Obstructive Sleep Apnea (OSA), CPAP
Sleep Apnea Biomarkers and Adherence to Continuous Positive Airway Pressure
Obstructive sleep apnea (OSA) is commonly assessed using the apnea-hypopnea index, although this measure does not fully reflect cardiovascular risk or the physiological impact of the disease.
- Conditions
- Obstructive Sleep Apnea (OSA), CPAP, Biomarkers for Prediction of OA Treatment Efficacy
- Trial name
- BIOSA (NCT07792746)
- Testing
- Continuous Positive Airway Pressure
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Millenaire
Obstructive Sleep Apnea (OSA)
Intermittent-Hypoxia Inhibits Neutrophil Extracellular Traps Formation: Role of Cathelicidins
The study will enroll 80 moderate-to-severe Obstructive sleep apnea (OSA) patients (40 obese) and 40 age-, gender-, and body mass index-matched controls.
- Trial name
- NCT07129486
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kun-Ta Chou
Sleep Apnea, Obstructive
Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep
This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is…
- Trial name
- Nasal vs Oral (NCT06789770)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Insomnia Disorder
Compound Ciwujia Granules in the Treatment of Insomnia
The goal of this multicenter, double-blind, double-dummy, randomized controlled trial was to examine the efficacy and safety of Compound Ciwujia Granules in the treatment of chronic insomnia.
- Trial name
- NCT07306494
- Testing
- Compound Ciwujia Granules group, Estazolam, Compound Ciwujia Granules and estazolam
- Volunteers
- 1,200 people
- Sponsor
- Hui Zhu
Insomnia
The PSP Sleep Course: An Online Sleep Intervention for Public Safety Personnel With Self-reported Sleep Difficulties.
This study evaluates an internet-delivered cognitive behavioural therapy for insomnia (ICBTi) intervention, known as the PSP Sleep Course, adapted for public safety personnel (PSP) experiencing sleep difficulties.
- Trial name
- NCT07021183
- Testing
- Sleep Course
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Regina
Obstructive Sleep Apnea
Device-Assisted Oropharyngeal Rehabilitation in Obstructive Sleep Apnea Patients Using Continuous Positive Airway Pressure
The goal of this clinical trial is to evaluate the effectiveness of device-assisted oropharyngeal rehabilitation (OPR) in improving upper airway muscle function and reducing obstructive sleep apnea (OSA) severity in adult…
- Trial name
- NCT06999746
- Testing
- Control, Oropharyngeal Exercise, Continuous positive airway pressure
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Cheng-Kung University Hospital
Obstructive Sleep Apnea, Hypertension
Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension
This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function.
- Trial name
- HRV-OSA-HTN (NCT07603583)
- Testing
- Polysomnography
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Armed Forces General Hospital
Musculoskeletal Discomfort, Ergonomic Risk Perception
Musculoskeletal Discomfort and Ergonomic Factors in Midwifery Students
The aim of this observational study is to assess regional musculoskeletal discomfort, ergonomic risk perception, and protective ergonomic behaviors among undergraduate midwifery students at Mardin Artuklu University, Türkiye.
- Conditions
- Musculoskeletal Discomfort, Ergonomic Risk Perception, Protective Ergonomic Behaviours, Clinical Task Exposure
- Trial name
- NCT07873567
- Where
- Turkey (Türkiye)
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Insomnia Chronic
Treatment of Insomnia in Primary Care Study
The goal of this clinical trial is to learn about insomnia treatment among primary care patients with chronic insomnia. The main question it aims to answer is: Does Sleep School (a therapy for insomnia) work well to decrease harm…
- Trial name
- TIP (NCT06149273)
- Testing
- Sleep School, Treatment as usual
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- University of Turku
Stressor, Individual, Alcohol Impairment
Neurobehavioral Changes Following Spaceflight Stressors
This study aims to investigate the impairing effects of known central nervous system (CNS) stressors in a controlled environment in order to predict and mitigate analogous risks in spaceflight.
- Conditions
- Stressor, Individual, Alcohol Impairment, Sleep Deprivation, Impairment, Cognitive
- Trial name
- NeuroSTAR (NCT07293494)
- Testing
- Alcohol Administration, Sleep Deprivation, Control
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Narcolepsy, Social Cognition
Evaluation of Social Cognition in Patient With Type 1 or Type 2 Narcolepsy Versus Patients With Idiopathic Hypersomnia
Narcolepsy is a chronic disabling neurologic disorder mainly characterised by excessive daytime sleepiness. Type 1 narcolepsy is associated with a deficit of hypocretin in the cerebrospinal fluid responsible for the cataplexy…
- Trial name
- COGNAR (NCT05773872)
- Testing
- Questionary
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Sleep Apnea, Obstructive
Pediatric Obstructive Sleep Apnea Diagnosis by Respiratory Polygraphy
Respiratory polygraphy (RP) can be used to detect obstructive sleep apnea syndrome in children (OSA) , but it underestimates the obstructive apnea-hypopnea index (OAHI) because hypopneas associated with cortical arousals are not…
- Trial name
- NCT06754800
- Testing
- Polysomnography in routine care
- Where
- France
- Volunteers
- 95 people
- Sponsor
- Central Hospital, Nancy, France
Autism Spectrum Disorder, Sleep Disturbance
Internet-delivered Cognitive Behaviour Therapy for Sleep Problems in ASD
This trial investigates the behavioural effects of Internet-based Cognitive behaviour therapy for insomnia (CBT-I) in adolescents with autism spectrum disorder with sleep problems. This is a randomised controlled trial.
- Conditions
- Autism Spectrum Disorder, Sleep Disturbance, Insomnia
- Trial name
- NCT03624400
- Testing
- Internet-based CBT-I, Internet-based psychoeducation
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Stockholm University
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