Clinical trials: Sleep Restriction
Sleep Restriction Then Total Sleep Deprivation, Total Sleep Deprivation Then Sleep Restriction
Phenotypic and Genotypic Markers of Performance Vulnerability to Sleep Loss
Insufficient sleep is common, affecting 20-40% of adults, and resulting from sleep disorders, medical conditions, work demands, stress/emotional distress, and social/domestic responsibilities.
- Trial name
- NCT02130791
- Testing
- Sleep
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sleep Deprivation, Sleep
Effects of Napping in Sleep-Restricted Adolescents
To examine the neurobehavioural responses to two successive cycles of sleep restriction and recovery in adolescents, and to determine the benefits of napping on cognitive performance, alertness, and mood.
- Trial name
- NCT02838095
- Testing
- Nap
- Where
- Singapore
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Obesity & Overweight
Effects of a 12-Week Individualized Energy-Restricted Diet on Perceived Stress and Serum Cortisol in Adults With Overweight or Obesity
This prospective interventional study investigated changes in perceived stress, serum cortisol concentrations, body weight, and body composition during a 12-week individualized energy-restricted dietary intervention in adults…
- Trial name
- NCT07873762
- Testing
- Energy-Restricted Mediterranean-Style Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Acibadem University
Sleep Deprivation
Physiologic Effects of Sleep Restriction
Evidence suggests a relationship between sleep deprivation and cardiovascular disease. The investigators wish to determine whether 9 nights of modest sleep restriction results in activation of cardiovascular disease mechanisms…
- Trial name
- NCT01433315
- Testing
- sleep restriction
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Non-Alcoholic Fatty Liver Disease, Obese
Fatty Liver in Obesity: Long-lifestyle Follow-up (FLiO)
Non-alcoholic fatty liver disease (NAFLD) is a condition of excessive hepatic lipid accumulation in subjects that consume less than 20g ethanol per day, without other known causes as drugs consumption or toxins exposure.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obese, Overweight
- Trial name
- FLiO (NCT03183193)
- Testing
- Control diet, FLiO diet
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Sleep, Cardiovascular Disease
Impact of Sleep Restriction in Women
The overall goal of this project is to test the hypothesis that long-term, sustained sleep restriction (SR), in women, will lead to increased cardio-metabolic risk.
- Conditions
- Sleep, Cardiovascular Disease, Obesity
- Trial name
- NCT02835261
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Columbia University
Sleep
Sleep and Food-based Decision Making
This study administers two prescribed sleep levels, each lasting one week, that participants will complete in their at-home environment.
- Trial name
- NCT05728983
- Testing
- Sleep levels
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Hypertension
Sleep Restriction and Parental History of Hypertension
The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal…
- Trial name
- NCT06482814
- Testing
- Partial sleep deprivation (sleep restriction), Normal sleep
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Mobility Limitation, Sleep Quality
Use Modular Medical Equipment Vehicle in Mobilization of Patient With Chest Tube
in this study, it was aimed to examine the effect of the modular carrying system on the outcomes of care in the mobilization of patients with a chest tube.
- Conditions
- Mobility Limitation, Sleep Quality, Pain, Comfort
- Trial name
- NCT05081856
- Testing
- mobilization with moduler medical equipment carring vehicle
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people
- Sponsor
- Istanbul Medipol University Hospital
Obstructive Sleep Apnea
Weight Loss and Obstructive Sleep Apnea
The purpose of this study is to evaluate the effects of moderate energy restriction on the body adiposity, severity of OSA, blood pressure, sympathetic activity, oxidative stress, inflammatory biomarkers, metabolic profile and…
- Trial name
- NCT02206126
- Testing
- Energy Restriction
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Autism Spectrum Disorder (ASD), Autism
Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism
The purpose of this open label trial is to examine the acceptability, tolerability, and feasibility and preliminary effectiveness of sleep restriction therapy for sleep problems in children with autism spectrum disorder (ASD).
- Trial name
- NCT06627205
- Testing
- Sleep Restriction Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Stanford University
Critical Illness, Sleep Disturbance
Mobilisation in the EveNing to TreAt Delirium
Patients with severe illness require lifesaving treatment in intensive care units. Around a third of patients admitted to intensive care develop delirium. This is a severe state of confusion.
- Conditions
- Critical Illness, Sleep Disturbance, Mobility Limitation, Intensive Care Unit Delirium
- Trial name
- MENTAL (NCT05401461)
- Testing
- Evening mobilisation
- Where
- 2 sites in United Kingdom
- Volunteers
- 58 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Sleep
Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults
This study aims to assess whether slow wave sleep enhancement using SmartSleep technology benefits daytime cognitive performance during periods of chronic sleep restriction.
- Trial name
- NCT03911154
- Testing
- Philips SmartSleep Technology--Continuous Fixed Interval modality, Philips SmartSleep Technology--Block modality, Philips SmartSleep Technology--In-Phase Adjustable modality
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Time Restricted Eating, Intermittent Fasting
Time-restricted Eating and Cognition
This study aims to investigate how time-restricted eating (TRE), more specifically TRE at different times (early vs late in the day), influences brain activity, behavior, decision-making, food intake, physical activity, the gut…
- Trial name
- NCT06508255
- Testing
- Early Time-Restricted Eating, Late Time-Restricted Eating
- Where
- Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Upper Airway Resistance Syndrome
Efficacy of Oral Appliance for Upper Airway Resistance Syndrome
Introduction: The Upper Airway Resistance Syndrome (UARS) is a sleep disorder characterized by airway resistance to breathing during sleep that leads to arousals and daytime sleepiness.
- Trial name
- NCT02636621
- Testing
- Brazilian Dental Appliance
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Sleep Restriction
Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women
The purpose of this study is to 1) determine how hypothalamic-pituitary-adrenal axis (HPA axis) activation occurs with sleep restriction and 2) evaluate how hypothalamic-pituitary-gonadal axis (HPG axis) deactivation occurs with…
- Trial name
- NCT04037605
- Testing
- Ketoconazole Pill (also known as nizoral), Ganirelix, Dexamethasone Pill
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Sleep, Appetitive Behavior
Time-restricted Eating, Appetite and Sleep
The goal of this clinical trial is to learn about the effect of time-restricted eating (TRE) to 10 hours per day on the regulation of appetite, the desire to eat, and the quality and duration of nocturnal sleep in adults with…
- Trial name
- SLEEPFAST (NCT06485037)
- Testing
- Time-restricted eating
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Chile
Sleep, Sleep Restriction
Effects of Sleep Restriction on Female Soccer Players: Physical Performance, Muscle Damage, Inflammation, and BDNF Levels.
This research aims to investigate the interplay between menstrual cycles, sleep patterns, and athletic performance. Before experimental sessions, participants will maintain menstrual diaries for three months and complete…
- Trial name
- NCT06251362
- Testing
- Sleep restriction
- Where
- 2 sites in Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Sleep Deprivation, Obesity
Sleep Restriction and Postprandial Lipemia
Sleep restriction increases overnight and early morning non-esterified fatty acids (NEFA) levels, which are correlated with whole-body decreases in insulin sensitivity, consistent with the observed impairment of intracellular…
- Trial name
- NCT05713370
- Testing
- high fat meal
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Overweight and Obesity
Time-restricted Feeding as a Dietary Strategy Against Metabolic Disturbances in Humans
This human dietary intervention study with a cross-over design aims to compare the effects of two isocaloric diets - early time-restricted feeding (TRF) vs.
- Trial name
- ChronoFast (NCT04351672)
- Testing
- Early Time-Restricted Feeding, Late Time-Restricted Feeding
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- German Institute of Human Nutrition