Clinical trials: Sleep Wake Disorders, open to volunteers
Obstructive Sleep Apnea, Hypertension
Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension
This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function.
- Trial name
- HRV-OSA-HTN (NCT07603583)
- Testing
- Polysomnography
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Kaohsiung Armed Forces General Hospital
4-7-8 Breathing Technique
The Effects of the 4-7-8 Breathing Technique on Sleep Quality, Pain, and Recovery Outcomes in Patients Undergoing Transurethral Resection of the Bladder
The aim of this study was to determine the effects of the 4-7-8 breathing technique on sleep quality, pain, and recovery quality in patients undergoing transurethral resection of the bladder (TUR-B).
- Trial name
- NCT07457086
- Testing
- 4-7-8 breathing technique
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Parkinson's Disease, Insomnia
Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's Disease
The aim of this study is to explore the effects of the dual orexin receptor antagonist Lemborexant on improving motor and sleep comorbidity in patients with Parkinson's disease.
- Conditions
- Parkinson's Disease, Insomnia, Motor Disorder
- Trial name
- NCT07384429
- Testing
- Lemborexant
- Where
- China
- Volunteers
- 44 people
- Sponsor
- YangPan
Obstructive Sleep Disordered Breathing
Characterization of the Tongue in Children With Obstructive Sleep-disordered Breathing
The tongue plays a key role in maintaining upper airway patency during sleep, mainly through the genioglossus, the principal pharyngeal dilator muscle.
- Trial name
- NCT07861230
- Testing
- Cross-sectional assessment
- Where
- Belgium
- Volunteers
- 39 people
- Sponsor
- Université Catholique de Louvain
Insomnia, Sleep Disturbance
Improving Sleep to Prevent Depression & Anxiety in Adolescents at High Risk
Emerging evidence has shown that sleep interventions such as Cognitive Behavioral Therapy for Insomnia (CBT-I) improve depressive and anxiety symptoms in adults, even when the intervention is brief, such as four to six sessions.
- Conditions
- Insomnia, Sleep Disturbance, Depressive Symptoms, Anxiety Symptoms
- Trial name
- NCT06358495
- Testing
- Cognitive Behavioral Therapy for Insomnia, Active Control
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Menopause, Menopause Hot Flashes
Haelan 951 for Menopause Symptoms in Peri- and Postmenopausal Women
This proof-of-concept, open-label, single-arm study is designed to evaluate the effects of daily consumption of Haelan 951, a fermented soy conventional food product, on self-reported menopausal vasomotor symptoms, sleep quality…
- Conditions
- Menopause, Menopause Hot Flashes, Menopause Related Conditions
- Trial name
- H951-MENO (NCT07751029)
- Testing
- Haelan 951
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Spectrum Clinical Research, LLC
Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea
Empirical CPAP Therapy for Suspected Obstructive Sleep Apnea in a Resource-Limited Setting
Obstructive sleep apnea (OSA) is a condition where a person's airway repeatedly collapses during sleep, causing them to stop breathing briefly and disrupting their rest.
- Conditions
- Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea, Sleep Apnea Syndromes
- Trial name
- NCT07693101
- Volunteers
- 80 people
- Sponsor
- Assiut University
Obstructive Sleep Apnea of Adult
Efficacy of Oropharyngeal Exercises for Patients With Obstructive Sleep Apnea Using Mandibular Advancement Device
Oropharyngeal muscle training has emerged as a novel adjunctive treatment approach, involving training of the swallowing muscle group and tongue muscles to prevent tongue collapse, reduce tongue base volume during sleep, and…
- Trial name
- NCT06103630
- Testing
- Oropharyngeal Exercises, Mandibular advancement device
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Cheng-Kung University Hospital
Sleep Disturbances, PMDD
Evaluating the Impact of Psychoeducation and Sleep-informed Workshop Targeting Sleep Concerns in Women and Individuals With Premenstrual Dysphoric Disorder
Premenstrual Dysphoric Disorder (PMDD) is a cyclical mood disorder characterized by emotional, cognitive, physical, and sleep-related symptoms that occur in the days leading up to menstruation and improve shortly after…
- Conditions
- Sleep Disturbances, PMDD, PMS
- Trial name
- PMDD (NCT07554950)
- Testing
- Psychoeducation and Sleep-Informed Workshop
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Sleep, Sleep Quality
A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children
The main goal of this study is to evaluate the "SIESTA" intervention, a culturally and contextually tailored sleep hygiene intervention that has the potential to exert greater improvements in sleep hygiene and sleep outcomes for…
- Conditions
- Sleep, Sleep Quality, Intervention Study, Ethnic Minority
- Trial name
- SIESTA (NCT06942455)
- Testing
- SIESTA, Sleep education and health education control
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Sleep Disorder, Mental Health Issue
Improving Sleep in a Psychiatric Hospital
The purpose of this study is to examine effects of sleep promotion versus treatment as usual (TAU) on subjective, self-reported sleep while in inpatient psychiatric treatment, to examine effects of sleep promotion vs.
- Trial name
- NCT07010718
- Testing
- Scented Oil, Ear Plugs, Eye Mask
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Insomnia, ADHD
Efficacy of Cognitive Behavioural Therapy for Insomnia and Bright Light Therapy in Adolescents With ADHD, Insomnia, and Evening Chronotype
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterised by persistent inattention, hyperactivity, and impulsivity.
- Conditions
- Insomnia, ADHD, Eveningness, Chronotype
- Trial name
- NCT07767617
- Testing
- CBT-I with Bright Light Group
- Where
- Hong Kong
- Volunteers
- 150 people
- Sponsor
- The University of Hong Kong
Insomnia
WELT-REST: WELT Randomized Evaluation of Sleep Therapy
The goal of this clinical trial is to learn whether the SleepQ mobile app can help reduce insomnia symptoms in adults diagnosed with insomnia.
- Trial name
- WELT-REST (NCT07289217)
- Testing
- SleepQ Digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- WELT corp
Internet Addiction Level, Quality of Sleep
Internet Addiction and Sleep Quality Among Medical Students
Internet addiction has become increasingly prevalent among medical students and may negatively affect sleep quality and academic performance.
- Conditions
- Internet Addiction Level, Quality of Sleep, Medical Students, Academic Performance
- Trial name
- NCT07609784
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Sohag University
Idiopathic Hypersomnia
A Study of TAK-360 in Adults With Idiopathic Hypersomnia
Idiopathic Hypersomnia (IH) is a condition where people feel extremely sleepy during the day, especially in the morning, even if they sleep a lot at night.
- Trial name
- NCT06812078
- Testing
- TAK-360
- Where
- 29 sites in United States, France and 4 more
- Volunteers
- 96 people
- Sponsor
- Takeda
Insomnia Chronic
Treatment of Insomnia in Primary Care Study
The goal of this clinical trial is to learn about insomnia treatment among primary care patients with chronic insomnia. The main question it aims to answer is: Does Sleep School (a therapy for insomnia) work well to decrease harm…
- Trial name
- TIP (NCT06149273)
- Testing
- Sleep School, Treatment as usual
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- University of Turku
Insomnia, TBI (Traumatic Brain Injury)
Behavioral Treatment of Insomnia in Active-Duty Service Members With Traumatic Brain Injury
The objective of the study is to conduct a randomized controlled trial of Cognitive Behavioral Therapy for Insomnia (CBT-I) in a sample of active-duty sailors with a history of traumatic brain injury (TBI).
- Trial name
- CBTBI (NCT06867666)
- Testing
- In Person CBT-I, CBT-I via COAST
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Noctem, LLC
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Asthma Control, Pulmonary Function
Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study
The primary goal of this study is to investigate the comparative long-term (i.e., 1-year) effectiveness of energy recovery ventilators (ERVs) and portable air cleaners (PACs) in reducing indoor air pollutants and mold levels and…
- Conditions
- Asthma Control, Pulmonary Function, Quality of Life, Stress
- Trial name
- NCT07196436
- Testing
- Energy Recovery Ventilator, Portable Air Cleaner
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas at Arlington
Obstructive Sleep Apnea
Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy
Obstructive sleep apnea (OSA) is a disorder where a person has recurrent choking episodes during sleep. Surgery can treat OSA and drug induced sleep endoscopy (DISE) is a procedure that surgeons use to evaluate the throat while a…
- Trial name
- DISE-Pulm (NCT05350332)
- Testing
- Negative Pressure Ventilator, Pulmonary Function Testing (PFT), Transcutaneous Phrenic Nerve Stimulation
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Emory University
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