Clinical trials: Sleep Wake Disorders, open to volunteers
Autism, Sleep Disturbances in Children
Differences in Rest, Emotion, and Arousal Modulation in Youth
The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10).
- Conditions
- Autism, Sleep Disturbances in Children, Sleep
- Trial name
- DREAMY-Autism (NCT07476937)
- Testing
- Power Down bedtime manipulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Patient Education, Surgical Fear and Worrying
The Effect of Video-Supported Online Preoperative Education on Fear, Anxiety, Sleep, and Stress
Gallbladder stone disease is among the most common digestive system problems worldwide. The global incidence of gallstones is estimated to be 10-20%. In Europe, this rate is approximately 20%.
- Conditions
- Patient Education, Surgical Fear and Worrying, Surgical Stress Response, Medical-surgical Nursing
- Trial name
- NCT07100275
- Testing
- Patient education, Follow-up via Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Bingol University
Insomnia, Insomnia Chronic
SHADES Mechanistic Trial
Cardiovascular disease (CVD) is common, deadly, and costly, and adults with insomnia represent a large group of people at elevated risk of developing CVD in the future.
- Conditions
- Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance
- Trial name
- SHADES (NCT06041581)
- Testing
- Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Core Temperature, Telomere Length, Mean Leukocyte
Mitigating Heat Stress Among Rickshaw Drivers in Bangladesh
The goal of the experimental study is to understand the impact of heat stress on core temperature and telomere length. Investigators will recruit rickshaw drivers who use manual power to push their rickshaws and randomly assign…
- Conditions
- Core Temperature, Telomere Length, Mean Leukocyte, Kidney Function Issue
- Trial name
- NCT06956430
- Testing
- Battery-powered rickshaw
- Volunteers
- 300 people
- Sponsor
- University of California, Berkeley
Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea
Empirical CPAP Therapy for Suspected Obstructive Sleep Apnea in a Resource-Limited Setting
Obstructive sleep apnea (OSA) is a condition where a person's airway repeatedly collapses during sleep, causing them to stop breathing briefly and disrupting their rest.
- Conditions
- Obstructive Sleep Apnea (OSA), Suspected Obstructive Sleep Apnea, Sleep Apnea Syndromes
- Trial name
- NCT07693101
- Volunteers
- 80 people
- Sponsor
- Assiut University
Sleep Apnea, Obstructives, Sleep Apnea Central
Development of a Torso Patch Sensor (C-TraQ) as a Companion Device to a Fingertip Sensor (TipTraQ) for Direct Monitoring of Respiratory Effort
The existing PranaQ system utilizes a fingertip sensor that captures PPG(Photoplethysmography) and accelerometer data, and its clinical validation is well-established.
- Trial name
- NCT07744854
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- PranaQ Pte. Ltd.
Minor, Scoliosis; Juvenile
Evaluation of a Prehabilitation Program in Patients Requiring Scoliosis Surgery.
Scoliosis is a curvature of the spine that, in the most severe cases, may require surgical treatment. This surgery is invasive and complex, causing anxiety for children, adolescents, and their parents.
- Conditions
- Minor, Scoliosis; Juvenile, Scoliosis; Adolescence, Surgery
- Trial name
- PHYPSYSCOL (NCT07852286)
- Testing
- Pre-habilitation program
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Grenoble
Sleep Apnea, Spinal Cord Injury
Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury
This study will investigate potential therapeutic approaches for sleep-disordered breathing (SDB) in patients with chronic cervical spine injury (>6 months post-injury).
- Trial name
- NCT02922894
- Testing
- Acute episodic hypoxia, Supplemental oxygen, Trazodone
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- John D. Dingell VA Medical Center
Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
Suvorexant for Treatment of AUD and PTSD
This study is to determine if suvorexant (SUV) will reduce insomnia in 76 men and women veteran and non-veterans between the ages 21-65 with posttraumatic stress disorder (PTSD) symptoms and alcohol use disorder (AUD).
- Conditions
- Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD), Insomnia
- Trial name
- SUV (NCT06679062)
- Testing
- Suvorexant
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Obstructive Sleep Apnea (OSA), CPAP
Sleep Apnea Biomarkers and Adherence to Continuous Positive Airway Pressure
Obstructive sleep apnea (OSA) is commonly assessed using the apnea-hypopnea index, although this measure does not fully reflect cardiovascular risk or the physiological impact of the disease.
- Conditions
- Obstructive Sleep Apnea (OSA), CPAP, Biomarkers for Prediction of OA Treatment Efficacy
- Trial name
- BIOSA (NCT07792746)
- Testing
- Continuous Positive Airway Pressure
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Clinique du Millenaire
Insomnia, Cardiorespiratory Fitness
Insomnia´s Impact on DNA Stability, Cardio-metabolic Health and Lifestyle Behaviors
Insomnia is a highly prevalent sleep disorder worldwide, with an increasing incidence in athletes, older adults, university students, and individuals with metabolic syndrome.
- Conditions
- Insomnia, Cardiorespiratory Fitness, Metabolic Disease
- Trial name
- INSIGHTS (NCT06869486)
- Testing
- Exercise, Bioelectrical Impedance, Micronucleus Assay
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Ischemic Stroke, Obstructive Sleep Apnea
Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke
The study aims to evaluate whether early treatment of obstructive sleep apnea with continuous positive airway pressure in ischemic stroke patients has a favorable effect on functional recovery.
- Trial name
- ATACS (NCT07044830)
- Testing
- CPAP
- Where
- Brazil
- Volunteers
- 425 people
- Sponsor
- Hospital das Clínicas de Ribeirão Preto
Insomnia Chronic, Narcolepsy
The Impact of Light, Electrical, and Magnetic Neuroregulation Interventions on Sleep-wake Disorders
Carry out precise and effective neuromodulation interventions, and develop new neuromodulation technologies for sleep disorders.
- Conditions
- Insomnia Chronic, Narcolepsy, REM Sleep Behavior Disorder
- Trial name
- NCT06797284
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Internet Addiction Level, Quality of Sleep
Internet Addiction and Sleep Quality Among Medical Students
Internet addiction has become increasingly prevalent among medical students and may negatively affect sleep quality and academic performance.
- Conditions
- Internet Addiction Level, Quality of Sleep, Medical Students, Academic Performance
- Trial name
- NCT07609784
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Sohag University
Insomnia, Mild Traumatic Brain Injury
Behavioral Insomnia Treatment in Mild Traumatic Brain Injury
This is a single site, two-armed random controlled trials (RCT) comparing six sessions of Cognitive Behavioral Therapy for Insomnia (CBT-I) with four sessions of Brief Behavioral Therapy for Insomnia (BBT-I) in service members…
- Trial name
- NCT06551987
- Testing
- Cognitive Behavioral Therapy for Insomnia, Brief Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Obesity & Overweight, Respiratory Depression
Oxytocin for Respiratory Compromise and Hypoventilation Induced by Drugs
Drug overdose is a national crisis. The primary cause of death associated with opioids is opioid-induced respiratory depression.
- Conditions
- Obesity & Overweight, Respiratory Depression, Intranasal Drug Administration, Oxytocin
- Trial name
- ORCHID (NCT07902752)
- Testing
- Intranasal Oxytocin 40 i.u.
- Volunteers
- 100 people
- Sponsor
- George Washington University
Restless Legs Syndrome
Blood Changes After Exercise in Restless Legs Syndrome
The goal of this clinical trial is to learn how exercise changes molecules in the blood in people with restless legs syndrome (RLS) to better understand the cause(s) of RLS.
- Trial name
- PEARLS (NCT06481176)
- Testing
- 12-Week RLS Exercise Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Neuropathology, Cognitive Decline
Sleep Impairment in Subjects at Risk of Developing Alzheimer's Disease
Alzheimer's disease (AD) is characterised by a progressive loss of memory and cognitive function. In the early stages of AD, there is a progressive accumulation of molecules: β-amyloid peptides (Aβ) in the brain.
- Conditions
- Neuropathology, Cognitive Decline, Sleep Disorder
- Trial name
- WAVE-APOE4 (NCT05649514)
- Testing
- Polysomnography, Neuropsychological assessment, Questionnaires on sleep and behavioural problems
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Loneliness, Fear of Missing Out
Social Media Diet and Psychological Outcomes in University Students
This study aims to examine the effect of a social media diet intervention on loneliness, fear of missing out (FoMO), and sleep quality among university students.
- Conditions
- Loneliness, Fear of Missing Out, Sleep Quality
- Trial name
- The Effect of (NCT07473791)
- Testing
- Social Media Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Acute Myocardial Infarction, Insomina
Impact of New-onset Insomnia After Coronary Revascularization for Patients With Acute Myocardial Infarction
The present study aimed to evaluate the impact of acute insomnia on long-term clinical outcomes in patients underwent PCI or CABG for AMI using the Korean National Health Insurance Service (NHIS) database, and to identify the…
- Trial name
- MI-INSOMINA (NCT07416617)
- Testing
- Insomnia medication, No insomnia medication
- Where
- South Korea
- Volunteers
- 235,342 people
- Sponsor
- Samsung Medical Center